A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information.

abstract：:Forty-four marsupials, 77 rodents and 161 ticks were captured in an Atlantic Forest Reserve in Cotia county, State of São Paulo, where human cases of Lyme disease (LD) simile were reported. Twenty-one borrelia-like spirochete isolates were recovered from the mammals' blood and rodent livers or spleens, and triturated ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abel IS,Marzagão G,Yoshinari NH,Schumaker TT

更新日期：2000-09-01 00:00:00

abstract：:An epidemic of sporotrichosis, a subcutaneous mycosis caused by the fungus Sporothrix schenckii, is ongoing in Rio de Janeiro, Brazil, in which cases of human infection are related to exposure to cats. In an attempt to demonstrate the zoonotic character of this epidemic using molecular methodology, we characterised by...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Reis RS,Almeida-Paes R,Muniz Mde M,Tavares PM,Monteiro PC,Schubach TM,Gutierrez-Galhardo MC,Zancopé-Oliveira RM

更新日期：2009-08-01 00:00:00

abstract：:Schistosomiasis in America with the exception of Brazil, behaves as a chronic mild disease with few clinical manifestations due to low parasite burden. These features restrict the clinical and parasitological diagnosis. The most commonly used stool examination method, Kato-Katz, becomes insensitive when the majority o...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Noya BA,Noya O,Balzan C,Cesari IM

更新日期：1992-01-01 00:00:00

abstract：:A simple and rapid method for differentiating the sibling species Biomphalaria tenagophila and Biomphalaria occidentalis by agarose gel electrophoresis (AGE) is described. Snail hemolymph is used as the test sample and the red coloration of the hemoglobin fraction permits visualization of the migration patterns withou...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bailey JB,Michelson EH,Paraense WL

更新日期：1986-07-01 00:00:00

abstract：:Infusions of Aspidosperma nitidum (Apocynaceae) wood bark are used to treat fever and malaria in the Amazon Region. Several species of this family are known to possess indole alkaloids and other classes of secondary metabolites, whereas terpenoids, an inositol and the indole alkaloids harmane-3 acid and braznitidumine...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coutinho JP,Aguiar AC,dos Santos PA,Lima JC,Rocha MG,Zani CL,Alves TM,Santana AE,Pereira Mde M,Krettli AU

更新日期：2013-12-01 00:00:00

abstract：:In recent years, the development of new tools to gather field information about vector ecological parameters has increased. This report evaluated the BG-Sentinel Trap (BGS-Trap), a promising new attempt to improve collection of the dengue vector, Aedes aegypti. The efficacy of the BGS-Trap was compared with the CDC ba...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Maciel-de-Freitas R,Eiras AE,Lourenço-de-Oliveira R

更新日期：2006-05-01 00:00:00

abstract：:As in many areas of Brazil, the AIDS epidemic in Curitiba is relatively stable, but surveillance is important to support public policy. The molecular characteristics of HIV may be instrumental for monitoring epidemic trends. We evaluated plasma HIV-1 RNA (n = 37) from 38 cases presenting with positive serology, who we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira JL,Thomaz M,Rodrigues R,Harrad D,Oliveira CM,Oliveira CA,Batista JP,Ito TS,Brigido LF

更新日期：2008-12-01 00:00:00

abstract：:Lutzomyia evandroi Costa Lima and Antunes, 1936 is found in Rio Grande do Norte, northeastern Brazil, in areas of visceral and mucocutaneous leishmaniasis and follows the same geographic distribution of L. longipalpis. The biological cycle, oviposition, morphological and behavioral characteristics of the species were ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Melo Ximenes Mde F,Maciel JC,Jerônimo SM

更新日期：2001-08-01 00:00:00

abstract：:This study was undertaken to investigate the prevalence of Mansonella ozzardi infection and to estimate the parasitic infection rate (PIR) in simuliid black flies in the municipality of Pauini, Amazonas, Brazil. We used thick blood films to examine 921 individuals in 35 riverine communities along the Pauini and Purus ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Medeiros JF,Py-Daniel V,Barbosa UC,Izzo TJ

更新日期：2009-02-01 00:00:00

abstract：:A key is presented for the identification of the adults of 54 species of bloodsucking ceratopogonids, 51 of which are known inhabitants of Argentina, and Culicoides uruguayensis Ronderos, C. pifanoi Ortiz, and C. trilineatus Fox, which are known to occur in bordering Uruguay and Paraguay. Wing photographs are provided...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Spinelli GR,Ronderos MM,Díaz F,Marino PI

更新日期：2005-04-01 00:00:00

abstract：:A list of 41 Apoidea (Hymenoptera) type specimens deposited in the Entomological Collection of the Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brazil is presented. The types previously belonged to the Zikán and Schrottky private collections. A total of 11 holotypes and 30 paratypes are listed with their respective dat...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferraz MV

更新日期：1997-05-01 00:00:00

abstract：:In C57Bl/6 strain mice vaccinated with radiation-attenuated cercariae of Schistosoma mansoni immune elimination of challenge parasites occurs in the lungs. Leucocytes were recovered from the lungs of such mice by bronchoalveolar lavage and cultured in vitro with larval antigen; the profile of cytokines released was th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Wilson RA

更新日期：1992-01-01 00:00:00

abstract：:The objective of this work was to characterize, and compare different morphological types of hemocytes of Rhodnius prolixus, Rhodnius robustus, Rhodnius neglectus, Triatoma infestans, Panstrongylus megistus, and Dipetalogaster maximus. This information provides the basis for studying the cellular immune systems of the...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Azambuja P,Garcia ES,Ratcliffe NA

更新日期：1991-01-01 00:00:00

abstract：:Raoultella planticola is an emerging zoonotic pathogen that is associated with rare but life-threatening cases of bacteremia, biliary tract infections, and urinary tract infections. Moreover, increasing antimicrobial resistance in the organism poses a potential threat to public health. In spite of its importance as a ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Huang YT,Chuang WY,Ho BC,Wu ZY,Kuo RC,Ko M,Liu PY

更新日期：2018-08-27 00:00:00

abstract：:Coagulase-negative staphylococci (CNS) have been identified as the etiological agent in various infections and are currently the microorganisms most frequently isolated in nosocomial infections. However, little is known about the virulence factors produced by CNS that contribute to the pathogenesis of infections cause...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cunha Mde L,Rugolo LM,Lopes CA

更新日期：2006-09-01 00:00:00

abstract：:Chronic Chagas disease diagnosis relies on laboratory tests due to its clinical characteristics. The aim of this research was to review commercial enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) diagnostic test performance. Performance of commercial ELISA or PCR for the diagnosis of chron...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brasil PE,Castro R,Castro Ld

更新日期：2016-01-01 00:00:00

abstract：:From October 2000 to April 2001, insecticide bioassays were conducted in 18 ranches from 10 counties in the states of Mato Grosso and Mato Grosso do Sul, in Central Brazil. Horn flies from wild populations were exposed to diazinon-impregnated filter papers immediately after collection on cattle, and mortality was reco...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barros AT,Gomes A,Ismael AP,Koller WW

更新日期：2002-09-01 00:00:00

abstract：:In this work, a murine experimental model of toxocariasis has been developed in BALB/c, C57BL/10 and C3H murine strains orally inoculated with 4,000 Toxocara canis embryonated eggs, in order to investigate the isotype-specific immune responses against excretory-secretory antigens from larvae. T. canis specific IgG+M, ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cuéllar C,Fenoy S,del Aguila C,Guillén JL

更新日期：2001-05-01 00:00:00

abstract：:Sixty eight patients with localized cutaneous leishmaniasis from an area with Leishmania (Viannia) braziliensis transmission had cultures performed with a modified Marzochís vacuum aspiratory puncture technique to establish sensitivity and contamination rate with this new method. Overall sensitivity of three aspirates...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Romero GA,Sampaio RN,Macedo Vde O,Marsden PD

更新日期：1999-07-01 00:00:00

abstract：:The transference of the genetic markers and the presence of DNA plasmidial in 240 cultures of Escherichia coli was investigated. The strains were originated from Waste Treatment Plant (inffluent and effluents) located in Ilha do Governador, Rio de Janeiro. By conjugation analysis, E. coli K 12 allowed the isolation of...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vincente AC,Dias JC,Hofer E

更新日期：1988-01-01 00:00:00

abstract：:Acoustic signalling has been extensively studied in insect species, which has led to a better understanding of sexual communication, sexual selection and modes of speciation. The significance of acoustic signals for a blood-sucking insect was first reported in the XIX century by Christopher Johnston, studying the hear...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vigoder Fde M,Ritchie MG,Gibson G,Peixoto AA

更新日期：2013-01-01 00:00:00

abstract：:The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume d...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dagger F,Valdivieso E,Marcano AK,Ayesta C

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:CD64 (FcγR1) is a high-affinity receptor for monomeric IgG1 and IgG3. Circulating neutrophils express very low amounts of CD64 on their surface. OBJECTIVES:Our primary aim was to investigate the utility of neutrophil CD64 surface expression as a biomarker of active pulmonary tuberculosis (TB). We hypothesis...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Corrêa RDS,Rodrigues LS,Pereira LHL,Nogueira OC,Leung J,Sousa MDS,Hacker MA,Siqueira HR,Capone D,Alves RLR,Pessolani MCV,Schmitz V,Pereira GMB

更新日期：2019-01-01 00:00:00

abstract：:Patterns of parasite abundance and prevalence are thought to be influenced by several host characteristics such as size, sex, developmental stage, and seasonality. We examined two obligatory ectoparasites of the bat Noctilio leporinus (L.) (Chiroptera, Noctilionidae) to test whether prevalence and abundance of Noctili...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Moura MO,Bordignon MO,Graciolli G

更新日期：2003-09-01 00:00:00

abstract：:Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric oxide (NO) production. We previously demonstrated the correlation between serum levels of NO and the severity of renal disease in patients with severe leptospir...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos CS,Azevedo EC,Soares LM,Carvalho MO,dos Santos AC,das Chagas AD Jr,da Silva CL,Chagas UM,dos Reis MG,Athanazio DA

更新日期：2013-06-01 00:00:00

abstract：:Studies on natural infection by Leishmania spp of sandflies collected in endemic and nonendemic areas can provide important information on the distribution and intensity of the transmission of these parasites. This study sought to investigate the natural infection by Leishmaniain wild female sandflies. The specimens w...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira EF,Casaril AE,Mateus NL,Murat PG,Fernandes WS,Oshiro ET,Oliveira AG,Galati EA

更新日期：2015-12-01 00:00:00

abstract：:Gryllophila cephalobulata n. sp. (Nematoda, Thelastomatidae) a parasite of the mole cricket Neocurtilla claraziana (Orthoptera, Gryllotalpidae) isolated in Buenos Aires Province, is described and illustrated. It is characterized by cuticle annulated all along the length of the body; the first ring has 4 lobules, the s...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Camino NB,Maiztegui B

更新日期：2002-07-01 00:00:00

abstract：:Ketoconazole, an azole antifungic drug which is already in the market has also been demonstrated to be active against Trypanosoma cruzi experimental infections. In this paper we confirmed the drug effect and investigated its range of activity against different T. cruzi strains naturally resistant or susceptible to bot...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brener Z,Cançado JR,Galvão LM,da Luz ZM,Filardi Lde S,Pereira ME,Santos LM,Cançado CB

更新日期：1993-01-01 00:00:00

abstract：:Major emergency efforts are being mounted for each vector-borne disease epidemiological crisis anew, while knowledge about the biology of arthropods vectors is dwindling slowly but continuously, as is the number of field entomologists. The discrepancy between the rates of production of knowledge and its use and need f...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Casas J,Lazzari C,Insausti T,Launois P,Fouque F

更新日期：2016-11-01 00:00:00

abstract：:The nematode parasites of Rhinella marina include species of the genus Rhabdias (Rhabdiasidae: Rhabditoidea). The present study describes Rhabdias paraensis sp. nov., which parasitizes the lungs of R. marina in Brazilian Amazonia. Of the more than 70 known species of this genus, 18 are parasites of bufonids, of which,...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos JN,Melo FT,Nascimento Lde C,Nascimento DE,Giese EG,Furtado AP

更新日期：2011-06-01 00:00:00