Adhesion of erythrocytes to endothelial cells after acute exercise: differences in red blood cells from juvenile and adult rats.

abstract：:To evaluate the role of chloride in the pathogenesis of salt-dependent deoxycorticosterone (DOC) hypertension, we studied young Wistar rats chronically loaded with sodium bicarbonate (NaHCO(3)) or sodium chloride (NaCl) which were administered either in the diet or in the drinking fluid. Selective sodium loading (with...

journal_title：Physiological research

authors： Kunes J,Zicha J,Jelínek J

更新日期：2004-01-01 00:00:00

abstract：:Monoaminergic neurotransmitter 5-hydroxytryptamine (5-HT), also known as serotonin, plays important roles in modulating the function of the olfactory system. However, thus far, the knowledge about 5-HT and its receptors in olfactory receptor neurons (ORNs) and their physiological role have not been fully characterized...

journal_title：Physiological research

authors： Gao S,Guo X,Liu T,Liu J,Chen W,Xia Q,Chen Y,Tang Y

更新日期：2013-01-01 00:00:00

abstract：:The paper presents an example of a new type of a structured model containing time delays in parallel branches. This model was selected as optimal to describe mathematically the lymphocyte migration between the venous blood and prescapular lymph in Merino ewes under physiological conditions. The model allowed to identi...

journal_title：Physiological research

authors： Dedík L,Durisová M,Srikusalanukul W,McCullagh P

更新日期：1999-01-01 00:00:00

abstract：:It is believed that omentin is secreted by stromal cells of adipose tissue and modulates insulin sensitivity. Data from a few studies have shown lower serum omentin in obese children and higher in anorexia nervosa. However, to date, there is lack of research on serum omentin concentrations in adolescent patients in a ...

journal_title：Physiological research

authors： Oświęcimska J,Suwała A,Świętochowska E,Ostrowska Z,Gorczyca P,Ziora-Jakutowicz K,Machura E,Szczepańska M,Kukla M,Stojewska M,Ziora D,Ziora K

更新日期：2015-01-01 00:00:00

abstract：:Hepcidin, a recently discovered antimicrobial peptide synthesized in the liver, was identified to be the key mediator of iron metabolism and distribution. Despite our knowledge of hepcidin increased in recent years, there are only limited data on hepcidin regulation during systemic inflammatory response in human subje...

journal_title：Physiological research

authors： Maruna P,Vokurka M,Lindner J

更新日期：2011-01-01 00:00:00

abstract：:Growth of the A549 cell line in a perfusion system suitable for use in a magnetic resonance study has been characterized and shown to be stable physiologically and hence appropriate for serial observations. Several methods of monitoring cell growth were compared to assess the behavior of the cells in this system. Comp...

journal_title：Physiological research

authors： Shankland EG,Livesey JC,Wiseman RW,Krohn KA

更新日期：2002-01-01 00:00:00

abstract：:Sodium borocaptate (BSH, Na2Bl2HllSH), a slow neutron-capture compound, was injected into the left forebrain ventricle of 1-week-old rats (150 microg BSH/3 microl phosphate buffered saline). After 90 min, the animals were irradiated by epithermal neutrons (LVR-15 nuclear reactor in Rez near Prague, flux density 8.8 x ...

journal_title：Physiological research

authors： Mares V,Lisá V,Bacáková L,Burian J

更新日期：1997-01-01 00:00:00

abstract：:Leptin and adiponectin, two adipocytokines, may work together in regulating energy homeostasis and insulin action. Leptin gene expression has been investigated in term placental tissue complicated by gestational diabetes mellitus (GDM), but never in conjunction with all isoforms of the leptin receptor (LEPR A-D), or w...

journal_title：Physiological research

authors： Meller M,Qiu C,Vadachkoria S,Abetew DF,Luthy DA,Williams MA

更新日期：2006-01-01 00:00:00

abstract：:Antagonists of GABA(B) receptors are expected to have proconvulsant action also in developing brain. Two antagonists (CGP55845 and CGP46381) were tested in a model of cortical epileptic afterdischarges (ADs) in 12-, 18- and 25-day-old rat pups with implanted electrodes. CGP55845 was dissolved in dimethylsulfoxide and ...

journal_title：Physiological research

authors： Mareš P

更新日期：2013-01-01 00:00:00

abstract：:The mood and behavior of individuals result from an orchestra of many factors. Among them steroids play an important role; however, only several common hormones have been investigated in this respect. It has been demonstrated that some steroid metabolites long considered merely the products of steroid hormone metaboli...

journal_title：Physiological research

authors： Dušková M,Hill M,Bičíková M,Šrámková M,Řípová D,Mohr P,Stárka L

更新日期：2015-01-01 00:00:00

abstract：:Senile dementia of Alzheimer's type (AD) is commonly characterized as a neurodegenerative disorder, which exhibits gradual changes of consciousness, loss of memory, perception and orientation as well as loss of personality and intellect. AD prevalence increases dramatically with age and is the fourth cause of death in...

journal_title：Physiological research

authors： Rípová D,Strunecká A

更新日期：2001-01-01 00:00:00

abstract：:Endometrial cancer is one of the most frequent gynecological malignancies present in more than 95 % of all uterine cancers. In spite of that, screening of such disease is not commonly performed in clinical practice due to enormous costs and relatively low sensitivity. Therefore, developing an effective screening test ...

journal_title：Physiological research

authors： Kacírová M,Bober P,Alexovič M,Tomková Z,Tkáčiková S,Talian I,Mederová L,Bérešová D,Tóth R,Andrašina I,Kožlejová Z,Kilík R,Divín R,Sabo J

更新日期：2019-12-30 00:00:00

abstract：:Exposure to hyperbaric oxygen leads to increased amount of reactive oxygen species (ROS) that are derived from various sources. After the discovery that ROS can function as signaling molecules, the idea of ROS being hazardous to biological tissues has been challenged. The aim of this study was to examine the changes i...

journal_title：Physiological research

authors： Gürdöl F,Cimşit M,Oner-Iyidoğan Y,Körpinar S,Yalçinkaya S,Koçak H

更新日期：2008-01-01 00:00:00

abstract：:A "pulse like" increase of cytoplasmic calcium concentration, which is proportional to ionophore concentration, is induced in red cells by exposure to A23187. Different Ca2+ levels are attained depending on cellular calcium buffering power and/or primary active calcium transport activation. We examined the effect of A...

journal_title：Physiological research

authors： Serrani RE,Gioia IA,Corchs JL

更新日期：1995-01-01 00:00:00

abstract：:Ubiquitination is a versatile tool used by all eukaryotic organisms for controlling the stability, function, and intracellular localization of a multitude of proteins. I will attempt to bring together our recent data on the down-regulation of two yeast model proteins, the galactose transporter Gal2 and fructose-1,6-bi...

journal_title：Physiological research

authors： Horák J

更新日期：2004-01-01 00:00:00

abstract：:We report that decreased expression of miR-30c in tumor compared to adjacent tissue is sex-dependent in colorectal cancer (CRC) patients. High expression of miR-30c was associated with better survival in the whole cohort. When the cohort was split into male and female subcohorts, decreased miR-30c expression in tumor ...

journal_title：Physiological research

authors： Herichova I,Reis R,Hasakova K,Vician M

更新日期：2020-12-31 00:00:00

abstract：:Resveratrol, which is a polyphenol present in red wines and vegetables included in human diets, exerts many biological effects. The aim of the present study was to investigate its effect on some activities of polymorphonuclear leukocytes, particularly the generation of superoxide anion ((O2)(-)) in whole blood, hypoch...

journal_title：Physiological research

authors： Cavallaro A,Ainis T,Bottari C,Fimiani V

更新日期：2003-01-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) has proven efficacious in reducing or even eliminating cardiac dyssynchrony and thus improving heart failure symptoms. However, quantification of mechanical dyssynchrony is still difficult and identification of CRT candidates is currently based just on the morphology and width o...

journal_title：Physiological research

authors： Kittnar O,Riedlbauchová L,Tomis J,LoŽek M,Valeriánová A,Hrachovina M,Mlček M,Huptych M,Janoušek J,Lhotská L

更新日期：2017-12-30 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) has an important role in the pathogenesis of retinopathy of prematurity (ROP) and inhibition of VEGF expression in the neovascular phase might prevent destructive neovascularization in ROP. It is suggested that retinoids exert a highly potent antiangiogenic activity by inhibit...

journal_title：Physiological research

authors： Ozkan H,Duman N,Kumral A,Kasap B,Ozer EA,Lebe B,Yaman A,Berk T,Yilmaz O,Ozer E

更新日期：2006-01-01 00:00:00

abstract：:We investigated and evaluated post-irradiation survival in cyclooxygenase-2-deficient (COX-2 KO) mice. Thirty-day survival following exposure of COX-2 KO mice to a lethal dose of 8.5 Gy of gamma-rays was observed to be statistically significantly lower in both males and females, as well as when the sexes were merged, ...

journal_title：Physiological research

authors： Hofer M,Hoferová Z,Gruzdev A,Dušek L,Falk M

更新日期：2018-11-14 00:00:00

abstract：:Numerous countermeasures have been proposed to minimize microgravity-induced physical deconditioning, but their benefits are limited. The present study aimed to investigate whether personalized aerobic exercise based on artificial gravity (AG) mitigates multisystem physical deconditioning. Fourteen men were assigned t...

journal_title：Physiological research

authors： Li XT,Yang CB,Zhu YS,Sun J,Shi F,Wang YC,Gao Y,Zhao JD,Sun XQ

更新日期：2017-09-22 00:00:00

abstract：:It was recognized that recombinant inbred strains are a very powerful system for the study of the genetics of hypertension, linkage analysis and gene mapping. Such set of recombinant inbred strains has been developed in the cooperation of Prof V. Kren and Dr. M. Pravenec in Prague. These recombinant inbred strains wer...

journal_title：Physiological research

authors： Kunes J,Zicha J

更新日期：1993-01-01 00:00:00

abstract：:Atrial fibrillation is associated with atrial remodeling, in which connexin 43 (Cx43) and cell hypertrophy play important roles. In this study, apelin-13, an aliphatic peptide, was used to explore the protective effects of the adenosine monophosphate-activated protein kinase (AMPK)/mTOR signaling pathway on Cx43 expre...

journal_title：Physiological research

authors： Chen Y,Qiao X,Zhang L,Li X,Liu Q

更新日期：2020-11-16 00:00:00

abstract：:The oxidative stress plays an important role in the development of cardiovascular diseases (CVD). In CVD progression an aberrant redox regulation was observed. In this regulation levels of reactive oxygen species (ROS) play an important role in cellular signaling, where Nrf2 is the key regulator of redox homeostasis. ...

journal_title：Physiological research

authors： Barančík M,Grešová L,Barteková M,Dovinová I

更新日期：2016-09-19 00:00:00

abstract：:TGF-beta superfamily members including bone morphogenetic proteins (BMPs) and their receptors (BMPR-1A, -1B and -2) have been shown to be important for reproductive function in both males and females, while information on the role of BMPs in males is limited. Functional studies on select BMPs and BMP receptors have de...

journal_title：Physiological research

authors： Ciller IM,Palanisamy SK,Ciller UA,McFarlane JR

更新日期：2016-11-08 00:00:00

abstract：:Hepcidin is a key regulator of iron metabolism and plays an important role in many pathologies. It is increased by iron administration and by inflammation, while erythropoiesis downregulates its expression. It decreases iron availability and thus contributes to anemia of chronic diseases. The aim of the study was to m...

journal_title：Physiological research

authors： Přikryl P,Hrušková Z,Konopásek P,Hladinová Z,Tesař V,Vokurka M

更新日期：2018-12-18 00:00:00

abstract：:Digitonin solubilizes mitochondrial membrane, breaks the integrity of the respiratory chain and releases two mobile redox-active components: coenzyme Q (CoQ) and cytochrome c (cyt c). In the present study we report the inhibition of glycerol-3-phosphate- and succinate-dependent oxygen consumption rates by digitonin tr...

journal_title：Physiological research

authors： Rauchová H,Vokurková M,Drahota Z

更新日期：2012-01-01 00:00:00

abstract：:The effect of suramin, an inhibitor of G protein regulated signalling, was studied on the membrane currents induced by noxious heat and by capsaicin in cultured dorsal root ganglia neurones isolated from neonatal rats. Whole-cell responses induced by a heat ramp (24-52 degrees C) were little affected by suramin. The n...

journal_title：Physiological research

authors： Vlachová V,Lyfenko A,Vyklický L,Orkand RK

更新日期：2002-01-01 00:00:00

abstract：:The effect of ethanol on the structural development of the central nervous system was studied in offspring of Wistar rats, drinking 20 % ethanol during pregnancy and till the 28th day of their postnatal life. The structural changes in the hippocampus and dentate gyrus were analyzed at the age of 18, 35 and 90 days. A ...

journal_title：Physiological research

authors： Milotová M,Riljak V,Jandová K,Bortelová J,Maresová D,Pokorný J,Langmeier M

更新日期：2008-01-01 00:00:00

abstract：:Sexually mature female Wistar rats were given daily intragastric doses of ethinylestradiol (EE) and levonorgestrel (LE) used normally in women: (1) 0.03 mg EE and 0.05 mg LE; (2) 0.04 mg EE and 0.075 mg LE; (3) 0.03 mg EE and 0.125 mg LE. All groups were treated for 6 months in 5-day cycles (four-day treatment with a ...

journal_title：Physiological research

authors： Nowaczyk-Dura G,Czekaj P

更新日期：1998-01-01 00:00:00