Abstract：
:The mood and behavior of individuals result from an orchestra of many factors. Among them steroids play an important role; however, only several common hormones have been investigated in this respect. It has been demonstrated that some steroid metabolites long considered merely the products of steroid hormone metabolism in fact possess considerable activity in the CNS. For this reason we studied the steroid metabolome including 50 analytes in 20 men with depression, 20 men with anxiety and 30 healthy controls. Significant differences were found not only between controls and men with either depression or anxiety, but also between men with depression and anxiety. Particularly striking were those steroids until now not generally associated with depression or anxiety, namely conjugated steroid forms, especially sulfates.
journal_name
Physiol Resjournal_title
Physiological researchauthors
Dušková M,Hill M,Bičíková M,Šrámková M,Řípová D,Mohr P,Stárka Ldoi
10.33549/physiolres.933067subject
Has Abstractpub_date
2015-01-01 00:00:00pages
S275-82issue
Suppl 2eissn
0862-8408issn
1802-9973pii
933067journal_volume
64pub_type
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