Three-dimensional electrogram in spherical coordinates: application to ischemia analysis.

Abstract:

:Three-dimensional electrogram was used for analysis of ischemia manifestation in isolated hearts. Three parameters based on spherical coordination system were used in this study - amplitude of electrical heart vector, its azimuth and elevation. The parameters were presented as a trend. This approach reflected ischemic changes in a manner which can be easily observed and evaluated. Ischemia was analysed in seven isolated hearts of New Zealand white rabbits. It was found that (a) ischemia changes heart electric vector, (b) ischemic preconditioning has a protective effect, and (c) both of these findings can be clearly observed by the proposed method.

journal_name

Physiol Res

journal_title

Physiological research

authors

Janousek O,Kolárová J,Nováková M,Provazník I

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

S51-8

eissn

0862-8408

issn

1802-9973

pii

932013

journal_volume

59 Suppl 1

pub_type

杂志文章,评审
  • Melatonin inhibits release of luteinizing hormone (LH) via decrease of [Ca2+]i and cyclic AMP.

    abstract::The role of [Ca2+]i and cAMP in transduction of the melatonin inhibitory effect on GnRH-induced LH release from neonatal rat gonadotrophs has been studied, because melatonin inhibits the increase of both intracellular messengers. Treatments increasing Ca2+ influx (S(-) Bay K8644 or KCI) or cAMP concentration (8-bromo-...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Vanecek J

    更新日期:1998-01-01 00:00:00

  • Glutathione reductase is inhibited by acetaminophen-glutathione conjugate in vitro.

    abstract::The aim of the present work was to investigate a new mechanism likely contributing to the toxic action of acetaminophen, especially to explore the possible inhibition of glutathione reductase through an acetaminophen-glutathione conjugate (APAP-SG). APAP-SG conjugate was synthesized by organic synthesis and purified b...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.931744

    authors: Rousar T,Pařík P,Kucera O,Bartos M,Červinková Z

    更新日期:2010-01-01 00:00:00

  • Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids.

    abstract::Plant-based n-3 polyunsaturated fatty acids (PUFA) possess a prospective antiatherogenic potential. Currant oil from Ribes nigrum L. is one of the few plant oils containing PUFAn-3 (15.3 mol%) in addition to PUFAn-6 (60.5 mol%). This study was aimed at comparing the effects of currant oil with those of lard fat, rich ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Vecera R,Skottová N,Vána P,Kazdová L,Chmela Z,Svagera Z,Walterá D,Ulrichová J,Simánek V

    更新日期:2003-01-01 00:00:00

  • Calcium intake and the outcome of short-term weight management.

    abstract::Experimental and epidemiological studies suggest that calcium intake is inversely related to weight gain. Calcium of dairy origin has been shown to be more effective in promoting weight loss. However, clinical studies yielded controversial results concerning the role of calcium intake in weight change. The aim of this...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Kabrnová-Hlavatá K,Hainer V,Gojová M,Hlavatý P,Kopský V,Nedvídková J,Kunesová M,Parízková J,Wagenknecht M,Hill M,Drbohlav J

    更新日期:2008-01-01 00:00:00

  • Transcriptomic analysis of left ventricle myocardium in an SHR congenic line with ameliorated cardiac fibrosis.

    abstract::Metabolic syndrome and one of its manifestations, essential hypertension, is an important cause of worldwide morbidity and mortality. Morbidity and mortality associated with hypertension are caused by organ complications. Previously we revealed a decrease of blood pressure and an amelioration of cardiac fibrosis in a ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934127

    authors: Mirchi LF,Chylíková B,Janků M,Šeda O,Liška F

    更新日期:2019-10-25 00:00:00

  • The increase in cAMP and cGMP levels in the oestrogenized rat hypophysis.

    abstract::Male and female rats were given oestradiol benzoate (1 mg s.c. twice a week for 3 weeks) and/or sodium nitroprusside (SN), a donor of nitric oxide (NO), which was administered in their food in amounts of 0.2 or 0.6 mg/rat/day. Neither oestradiol-induced hypertrophy of the hypophysis, nor the serum prolactin (PRL) leve...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Nedvídková J,Schreiber V

    更新日期:1992-01-01 00:00:00

  • Purinoceptors, renal microvascular function and hypertension.

    abstract::Proper renal blood flow (RBF) and glomerular filtration rate (GFR) are critical for maintaining normal blood pressure, kidney function and water and electrolyte homeostasis. The renal microvasculature expresses a multitude of receptors mediating vasodilation and vasoconstriction, which can influence glomerular blood f...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934463

    authors: Guan Z,Makled MN,Inscho EW

    更新日期:2020-07-16 00:00:00

  • Crowding-induced alterations in vascular system of Wistar-Kyoto rats: role of nitric oxide.

    abstract::The aim of this study was to determine the effect of chronic crowding on the cardiovascular system of Wistar-Kyoto (WKY) rats. Rats were randomly divided into the control (480 cm(2) per rat) or crowded (200 cm(2) per rat) group for eight weeks. Body weight, blood pressure (BP), heart rate and plasma nitrate/nitrite le...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Bernátová I,Púzserová A,Navarová J,Csizmadiová Z,Zeman M

    更新日期:2007-01-01 00:00:00

  • Long-term inhibition of NO synthase induces cardiac hypertrophy with a decrease in adrenergic innervation.

    abstract::Data concerning the effect of NO on the function and structure of the heart are controversial. We have studied two main questions: (i) Does the heart muscle reflect the hypertension induced by long-term inhibition of NO synthase? (ii) Since the arginine-NO pathway is also operative in the autonomic nervous system, the...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Gerová M,Hartmannová B,Dolezel S,Jezek L

    更新日期:1996-01-01 00:00:00

  • Research progress on flat epithelium of the inner ear.

    abstract::Sensorineural hearing loss and vertigo, resulting from lesions in the sensory epithelium of the inner ear, have a high incidence worldwide. The sensory epithelium of the inner ear may exhibit extreme degeneration and is transformed to flat epithelium (FE) in humans and mice with profound sensorineural hearing loss and...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934447

    authors: He L,Guo JY,Liu K,Wang GP,Gong SS

    更新日期:2020-11-16 00:00:00

  • Allosteric activation of yeast enzyme neutral trehalase by calcium and 14-3-3 protein.

    abstract::Neutral trehalase 1 (Nth1) from Saccharomyces cerevisiae catalyzes disaccharide trehalose hydrolysis and helps yeast to survive adverse conditions, such as heat shock, starvation or oxidative stress. 14-3-3 proteins, master regulators of hundreds of partner proteins, participate in many key cellular processes. Nth1 is...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:10.33549/physiolres.933950

    authors: Alblova M,Smidova A,Kalabova D,Lentini Santo D,Obsil T,Obsilova V

    更新日期:2019-04-30 00:00:00

  • Olfactory bulbectomy induced oxidative and cell damage in rat: protective effect of melatonin.

    abstract::In this study we analyzed the effects of melatonin (Mel, 1 mg/kg ip) on behavioral changes as well as cell and oxidative damage prompted by bilaterally olfactory bulbectomy. Olfactory bulbectomy caused an increase in lipid peroxidation products and caspase-3, whereas it prompted a decrease of reduced glutathione (GSH)...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.931684

    authors: Tasset I,Medina FJ,Peña J,Jimena I,Del Carmen Muñoz M,Salcedo M,Ruiz C,Feijóo M,Montilla P,Túnez I

    更新日期:2010-01-01 00:00:00

  • Radioprotective efficacy of dipyridamole and AMP combination in fractionated radiation regimen, and its dependence on the time of administration of the drugs prior to irradiation.

    abstract::We have recently demonstrated that the combined administration of dipyridamole and adenosine monophospate to mice induces radioprotective effects in terms of postirradiation haemopoietic recovery in animals irradiated with a single dose. The aim of the present experiments was to investigate the radioprotective ability...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Hofer M,Pospísil M,Netíková J,Znojil V,Vácha J,Holá J

    更新日期:1995-01-01 00:00:00

  • Glycation of myofibrillar proteins and ATPase activity after incubation with eleven sugars.

    abstract::Rat skeletal muscle myofibrils were incubated in the presence of D-glucose, D-fructose, D-galactose, D-ribose, D-tagatose, D-arabinose, D-xylose, D-mannose, L-sorbose, L-rhamnose or DL-glyceraldehyde and myofibrillar ATPase activity as well as the extent of glycation was measured. The attachment of sugars to proteins ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Syrový I

    更新日期:1994-01-01 00:00:00

  • The effect of HT-2 toxin on ovarian steroidogenesis and its response to IGF-I, leptin and ghrelin in rabbits.

    abstract::T-2 toxin and its metabolite HT-2 toxin are one of the most toxic mycotoxins of type A-trichothecenes, which are produced mainly by Fusarium species. Therefore, study of Fusarium toxins T-2 toxin and HT-2 toxin is an essential issue because they could also play role in failures of reproductive functions as well as end...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.933610

    authors: Kolesarova A,Maruniakova N,Kadasi A,Halenar M,Marak M,Sirotkin AV

    更新日期:2017-09-22 00:00:00

  • Restoration of Guyton´s diagram for regulation of the circulation as a basis for quantitative physiological model development.

    abstract::We present the current state of complex circulatory dynamics model development based on Guyton's famous diagram. The aim is to provide an open-source model that will allow the simulation of a number of pathological conditions on a virtual patient including cardiac, respiratory, and kidney failure. The model will also ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Kofránek J,Rusz J

    更新日期:2010-01-01 00:00:00

  • Arterial stiffening contributes to impairment of cerebrovascular reactivity in patients with coronary artery disease without carotid stenosis.

    abstract::Impaired cerebrovascular reactivity (CVR), an important risk factor for future stroke, is affected by a presence carotid stenosis. However, in some cases CVR can be impaired in the absence of carotid stenosis due to several poorly characterized mechanisms. We hypothesized that arterial stiffening as observed in corona...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932837

    authors: Rucka D,Marek J,Rucklova Z,Lubanda JC,Havranek S,Skvaril J,Varejka P,Chochola M,Karetova D,Korinek J,Linhart A

    更新日期:2015-01-01 00:00:00

  • Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats.

    abstract::Progressive compromise of antioxidant defenses and free radical-mediated lipid peroxidation, which is one of the major mechanisms of secondary traumatic brain injury (TBI), has also been reported in pediatric head trauma. In the present study, we aimed to demonstrate the effect of melatonin, which is a potent free rad...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Ozdemir D,Uysal N,Gonenc S,Acikgoz O,Sonmez A,Topcu A,Ozdemir N,Duman M,Semin I,Ozkan H

    更新日期:2005-01-01 00:00:00

  • Microcirculation in pregnancy.

    abstract::The microcirculation, like all physiological systems undergoes modifications during the course of pregnancy. These changes aid the adaption to the new anatomical and physiological environment of pregnancy and ensure adequate oxygen supply to the fetus. Even though the microcirculation is believed to be involved in maj...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:10.33549/physiolres.932511

    authors: Abdo I,George RB,Farrag M,Cerny V,Lehmann C

    更新日期:2014-01-01 00:00:00

  • Dyslipoproteinaemia in children with or without family history of premature myocardial infarction.

    abstract::In order to examine the relationship between certain risk factors for atherosclerosis and family history of myocardial infarction, we compared a group of children (n = 51) whose parents had survived myocardial infarction (n = 34) with a control group of children (n = 90) with a negative family history of atheroscleros...

    journal_title:Physiological research

    pub_type: 临床试验,杂志文章

    doi:

    authors: Raslová K,Hucková M

    更新日期:1995-01-01 00:00:00

  • Ca-ATPase of human myometrium plasma membranes.

    abstract::We determined and characterized the Mg2+-dependent, Ca2+-stimulated ATPase (Ca-ATPase) activity in cell plasma membranes from the myometrium of pregnant women, and compared these characteristics to those of the active Ca2+-transport already demonstrated in this tissue. Similarly to the Ca2+-transport system, the Ca2+-...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Carrera F,Proverbio T,Marín R,Proverbio F

    更新日期:2000-01-01 00:00:00

  • Composite hyaluronate-type I collagen-fibrin scaffold in the therapy of osteochondral defects in miniature pigs.

    abstract::The potential of novel scaffold containing sodium hyaluronate, type I collagen, and fibrin was investigated in the regeneration of osteochondral defects in miniature pigs. Both autologous chondrocyte-seeded scaffolds and non-seeded scaffolds were implanted into two defects located in the non-weight-bearing zone of the...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Filová E,Rampichová M,Handl M,Lytvynets A,Halouzka R,Usvald D,Hlucilová J,Procházka R,Dezortová M,Rolencová E,Kostáková E,Trc T,Stastný E,Kolácná L,Hájek M,Motlík J,Amler E

    更新日期:2007-01-01 00:00:00

  • Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.

    abstract::Obstructive sleep apnea (OSA) has been demonstrated to be implicated in disorder of insulin secretion and diabetes mellitus. In this study, we aimed to evaluate the protective role of tempol, a powerful antioxidant, in chronic intermittent hypoxia (IH)-induced pancreatic injury. The rat model of OSA was established by...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934010

    authors: Wang Y,Ai L,Hai B,Cao Y,Li R,Li H,Li Y

    更新日期:2019-06-30 00:00:00

  • Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.

    abstract::The present study was performed to evaluate the role of neuronal nitric oxide synthase (nNOS)-derived nitric oxide (NO) during the developmental phase of hypertension in transgenic rats harboring the mouse Ren-2 renin gene (TGR). The first aim of the present study was to examine nNOS mRNA expression in the renal corte...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Cervenka L,Kramer HJ,Malý J,Vanecková I,Bäcker A,Bokemeyer D,Bader M,Ganten D,Mitchell KD

    更新日期:2002-01-01 00:00:00

  • Low survival of mice following lethal gamma-irradiation after administration of inhibitors of prostaglandin synthesis.

    abstract::An impairment of the survival of mice subjected to whole-body gamma-irradiation with a lethal dose of 10 Gy and treated with a repeated postirradiation administration of prostaglandin synthesis inhibitors (PGSIs), indomethacin or diclofenac, was observed. Morphological examination of the gastrointestinal tract and the...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Hofer M,Pospísil M,Tkadlecek L,Viklická S,Pipalová I,Holá J

    更新日期:1992-01-01 00:00:00

  • Thyroid hormone receptor occupancy and biological effects of 3,5,3,-L-triiodothyronine (T3) in GH4C1 rat pituitary tumour cells.

    abstract::The GH4C1 pituitary cell line, an excellent model for a thyroid hormone action study, was used for determination of the relationship between thyroid hormone receptor occupancy and intensity of cell proliferation, prolactin (PRL) production, thyrotropin (TSH) inhibition and 3,5,3,-L-triiodothyronine (T3) receptor down-...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Filipcík P,Strbák V,Brtko J

    更新日期:1998-01-01 00:00:00

  • Monitoring of the boron neutron-capture reaction by a simple animal model.

    abstract::Sodium borocaptate (BSH, Na2Bl2HllSH), a slow neutron-capture compound, was injected into the left forebrain ventricle of 1-week-old rats (150 microg BSH/3 microl phosphate buffered saline). After 90 min, the animals were irradiated by epithermal neutrons (LVR-15 nuclear reactor in Rez near Prague, flux density 8.8 x ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Mares V,Lisá V,Bacáková L,Burian J

    更新日期:1997-01-01 00:00:00

  • ATP-binding cassette (ABC) transporters in human metabolism and diseases.

    abstract::The ATP-binding cassette (ABC) superfamily of active transporters involves a large number of functionally diverse transmembrane proteins. They transport a variety of substrates including amino acids, lipids, inorganic ions, peptides, saccharides, metals, drugs, and proteins. The ABC transporters not only move a variet...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:

    authors: Stefková J,Poledne R,Hubácek JA

    更新日期:2004-01-01 00:00:00

  • Effect of chronic cadmium exposure on antioxidant defense system in some tissues of rats: protective effect of selenium.

    abstract::The effects of selenium (Se) on antioxidant defense system in liver and kidneys of rats with cadmium (Cd)-induced toxicity were examined. Cd exposure (15 mg Cd/kg b.m./day as CdCl(2) for 4 weeks) resulted in increased lipid peroxidation (LP) in both organs (p<0.005 and p<0.01). Vitamin C (Vit C) was decreased in the l...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Ognjanović BI,Marković SD,Pavlović SZ,Zikić RV,Stajn AS,Saicić ZS

    更新日期:2008-01-01 00:00:00

  • Quaternary benzo[c]phenanthridine alkaloids as inhibitors of dipeptidyl peptidase IV-like activity baring enzymes in human blood plasma and glioma cell lines.

    abstract::Quaternary benzo[c]phenanthridine alkaloids (QBA), fagaronine (FA), sanguinarine (SA), chelerythrine (CHE) and the QBA extract from Macleya cordata (EX) exerted differential inhibitory effect on the hydrolytic activity of particular dipeptidyl peptidase (DPP)-like enzyme isolated from human blood plasma and from human...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Sedo A,Malík R,Vicar J,Simánek V,Ulrichová J

    更新日期:2003-01-01 00:00:00