Abstract：
:We determined and characterized the Mg2+-dependent, Ca2+-stimulated ATPase (Ca-ATPase) activity in cell plasma membranes from the myometrium of pregnant women, and compared these characteristics to those of the active Ca2+-transport already demonstrated in this tissue. Similarly to the Ca2+-transport system, the Ca2+-ATPase is Mg2+-dependent, stimulated by calmodulin, and inhibited by vanadate. The Km for Ca2+ activation is 0.40 microM, very similar to that found for active calcium transport, i.e. 0.25 microM. Consequently, this Ca2+-ATPase can be responsible for the active calcium transport across the plasma membranes of smooth muscle cells.
journal_name
Physiol Resjournal_title
Physiological researchauthors
Carrera F,Proverbio T,Marín R,Proverbio Fsubject
Has Abstractpub_date
2000-01-01 00:00:00pages
331-8issue
3eissn
0862-8408issn
1802-9973journal_volume
49pub_type
杂志文章abstract：:Continuous normobaric hypoxia (CNH) renders the heart more tolerant to acute ischemia/reperfusion injury. Protein kinase C (PKC) is an important component of the protective signaling pathway, but the contribution of individual PKC isoforms under different hypoxic conditions is poorly understood. The aim of this study ...
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journal_title：Physiological research
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journal_title：Physiological research
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