Abstract:
:Anthropogenic environmental pollutants affect many physiological, biochemical, and endocrine actions as reproduction, metabolism, immunity, behavior and as such can interfere with any aspect of hormone action. Microbiota and their genes, microbiome, a large body of microorganisms, first of all bacteria and co-existing in the host´s gut, are now believed to be autonomous endocrine organ, participating at overall endocrine, neuroendocrine and immunoendocrine regulations. While an extensive literature is available on the physiological and pathological aspects of both players, information about their mutual relationships is scarce. In the review we attempted to show various examples where both, endocrine disruptors and microbiota are meeting and can act cooperatively or in opposition and to show the mechanism, if known, staying behind these actions.
journal_name
Physiol Resjournal_title
Physiological researchauthors
Hampl R,Stárka Ldoi
10.33549/physiolres.934513subject
Has Abstractpub_date
2020-09-30 00:00:00pages
S211-S223issue
Suppl 2eissn
0862-8408issn
1802-9973pii
934513journal_volume
69pub_type
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pub_type: 临床试验,杂志文章
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