Endocrine disruptors and gut microbiome interactions.

Abstract:

:Anthropogenic environmental pollutants affect many physiological, biochemical, and endocrine actions as reproduction, metabolism, immunity, behavior and as such can interfere with any aspect of hormone action. Microbiota and their genes, microbiome, a large body of microorganisms, first of all bacteria and co-existing in the host´s gut, are now believed to be autonomous endocrine organ, participating at overall endocrine, neuroendocrine and immunoendocrine regulations. While an extensive literature is available on the physiological and pathological aspects of both players, information about their mutual relationships is scarce. In the review we attempted to show various examples where both, endocrine disruptors and microbiota are meeting and can act cooperatively or in opposition and to show the mechanism, if known, staying behind these actions.

journal_name

Physiol Res

journal_title

Physiological research

authors

Hampl R,Stárka L

doi

10.33549/physiolres.934513

subject

Has Abstract

pub_date

2020-09-30 00:00:00

pages

S211-S223

issue

Suppl 2

eissn

0862-8408

issn

1802-9973

pii

934513

journal_volume

69

pub_type

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