Projections of auditory cortex onto the inferior colliculus in the rat.

Abstract:

:The organization of the neocortical projection to the inferior colliculus (IC) was studied in 36 rats using retrograde transport of horseradish peroxidase (HRP) or horseradish peroxidase conjugated with lectin (WGA-HRP). Projection to the external and dorsal cortices originates in the temporal neocortical areas Te 1, Te 2 and Te 3 and in the parietal area Par 2. The corticocollicular projection is predominantly ipsilateral with a weak contralateral contribution. Projection to the rostromedial and rostrolateral part of the external cortex (EC) of the IC arises mainly from the areas Par 2 and Te 1. The participation of the cortical areas Te 2 and Te 3 in this projection is only small. The fibres to the caudobasal part of the external cortex descend from the caudal parts of areas Te 1, Te 2, and Te 3. The corticocollicular projections to the dorsal part of the IC are more numerous than the projections to the EC and originate in all temporal areas, i.e. in area Te 1, Te 2 and Te 3. However, the topographical organization of the corticocollicular projection is more pronounced in the part which projects to the EC. We suggest that the topographical organization of the projections to the EC corresponds with the map of auditory space in the EC. The source of corticocollicular fibres are exclusively neurones of lamina V of all cortical areas sending their fibres to the IC.

journal_name

Physiol Res

journal_title

Physiological research

authors

Druga R,Syka J,Rajkowska G

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

215-22

issue

3

eissn

0862-8408

issn

1802-9973

journal_volume

46

pub_type

杂志文章
  • The role of non-aromatizable testosterone metabolite in metabolic pathways.

    abstract::Dihydrotestosterone (DHT) originates via irreversible reduction of testosterone by catalytic activity of 5alpha-reductase enzyme and it is demonstratively the most effective androgen. Androgens influence adipose tissue in men either directly by stimulation of the androgen receptor or indirectly, after aromatization, b...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:10.33549/physiolres.932080

    authors: Dušková M,Pospíšilová H

    更新日期:2011-01-01 00:00:00

  • Microarray analysis of normal and abnormal chick ventricular myocardial development.

    abstract::The left and right ventricle originate from distinct parts of the cardiac tube, and several genes are known to be differentially expressed in these compartments. The aims of this study were to determine developmental differences in gene expression between the left and right ventricle, and to assess the effect of alter...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932379

    authors: Krejčí E,Pesevski Z,DeAlmeida AC,Mrug M,Fresco VM,Argraves WS,Barth JL,Cui X,Sedmera D

    更新日期:2012-01-01 00:00:00

  • Effects of acoustic stimuli on neuronal activity in the auditory cortex of the rat.

    abstract::Spontaneous activity of cortical neurons exhibits alternative fluctuations of membrane potential consisting of phased depolarization called "up-state" and persistent hyperpolarization called "down-state" during slow wave sleep and anesthesia. Here, we examined the effects of sound stimuli (noise bursts) on neuronal ac...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932086

    authors: Zhang Y,Han L,Xiao X,Hu B,Ruan H,Xiong Y

    更新日期:2011-01-01 00:00:00

  • Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.

    abstract::Obstructive sleep apnea (OSA) has been demonstrated to be implicated in disorder of insulin secretion and diabetes mellitus. In this study, we aimed to evaluate the protective role of tempol, a powerful antioxidant, in chronic intermittent hypoxia (IH)-induced pancreatic injury. The rat model of OSA was established by...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934010

    authors: Wang Y,Ai L,Hai B,Cao Y,Li R,Li H,Li Y

    更新日期:2019-06-30 00:00:00

  • Purinoceptors, renal microvascular function and hypertension.

    abstract::Proper renal blood flow (RBF) and glomerular filtration rate (GFR) are critical for maintaining normal blood pressure, kidney function and water and electrolyte homeostasis. The renal microvasculature expresses a multitude of receptors mediating vasodilation and vasoconstriction, which can influence glomerular blood f...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934463

    authors: Guan Z,Makled MN,Inscho EW

    更新日期:2020-07-16 00:00:00

  • Mitochondrial adaptations in aged skeletal muscle: effect of exercise training.

    abstract::The aging process is associated with a decline in mitochondrial functions. Mitochondria dysfunction is involved in initiation and progression of many health problems including neuromuscular, metabolic and cardiovascular diseases. It is well known that endurance exercise improves mitochondrial function, especially in t...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:10.33549/physiolres.933329

    authors: Ziaaldini MM,Hosseini SR,Fathi M

    更新日期:2017-03-31 00:00:00

  • Effect of an increase in coronary perfusion on transmural ventricular repolarization.

    abstract::The effect of increased coronary flow on transmural ventricular repolarization was investigated in six pentobabital-anesthetized sheep. Fresh blood at 10 ml/min was injected into the left circumflex coronary artery (LCX) in addition to the normal coronary flow. Unipolar electrocardiograms were simultaneously registere...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Zhang YZ,He B,Wang LX

    更新日期:2007-01-01 00:00:00

  • Markers of oxidative stress and antioxidant status in the plasma, urine and saliva of healthy mice.

    abstract::Oxidative stress markers are usually measured in plasma, a stable environment for biomarkers. Blood collection is invasive, but the use of alternative biofluids is limited, due to high variability. In this study, we aimed to establish reference values for oxidative stress markers in plasma, urine and saliva of adult, ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.933866

    authors: Gyurászová M,Kovalčíková A,Janšáková K,Šebeková K,Celec P,Tóthová Ľ

    更新日期:2018-12-18 00:00:00

  • Analysis of relations between serum levels of epitestosterone, estradiol, testosterone, IGF-1 and prostatic specific antigen in men with benign prostatic hyperplasia and carcinoma of the prostate.

    abstract::Epitestosterone competes with testosterone for androgen receptors and inhibits several enzymes of steroidogenesis. Insulin-like growth factors (IGFs) stimulate the growth of prostate cells and directly activate androgen receptors in prostatic tumor cell lines. The prostate-specific antigen (PSA) decreases the affinity...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Hill M,Bílek R,Safarík L,Stárka L

    更新日期:2000-01-01 00:00:00

  • The effect of goldthioglucose on peroxidative processes in mice.

    abstract::Experiments were conducted to study the effect of goldthioglucose (GTG) upon the processes associated with lipid peroxidation. The glucose-6-phosphate dehydrogenase activity (G6PD; E.C. 1. 1.1.49) in red blood cells (RBC) and the amount of malonaldehyde precursors (MDA) per gram of brain, liver and kidney were determi...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Kostová D,Michnová E

    更新日期:1999-01-01 00:00:00

  • Vascular stenosis asymmetry influences considerably pressure gradient and flow volume.

    abstract::Vascular stenosis is often described only by its percentage in both clinical and scientific praxis. Previous studies gave inconclusive results regarding the effect of stenosis eccentricity on its hemodynamic effect. The aim of this experimental study was to investigate and quantify the effect of stenosis severity and ...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932944

    authors: Novakova L,Kolinsky J,Adamec J,Kudlicka J,Malik J

    更新日期:2016-01-01 00:00:00

  • Comparison of morphological changes of muscle fibers in response to dynamic electrical muscle contraction and dynamic hydraulic stimulation in a rat hindlimb disuse model.

    abstract::This study attempted to compare the muscle fiber morphological responses to dynamic electrical muscle stimulation (DEMS) and dynamic hydraulic stimulation (DHS) in rats under hindlimb suspension (HLS). DEMS at 1 Hz, 50 Hz and 100 Hz for 10 min/day, 5 days/week were introduced to the animals' right quadriceps. Static a...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.933101

    authors: Hu M,Lam H,Yeh R,Teeratananon M,Qin YX

    更新日期:2017-07-18 00:00:00

  • Ameliorative effect of sesamin in cisplatin-induced nephrotoxicity in rats by suppressing inflammation, oxidative/nitrosative stress, and cellular damage.

    abstract::Nephrotoxicity of cisplatin (CP) involves renal oxidative stress and inflammation, and sesamin (a major liganin in many plants) has strong antioxidant and antiinflammatory actions. Therefore, we investigated here the possible mitigative action of sesamin on CP nephrotoxicity in rats. Sesamin was given orally (5 mg/kg/...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934142

    authors: Ali BH,Al Salam S,Al Suleimani Y,Al Za'abi M,Ashique M,Manoj P,Sudhadevi M,Al Tobi M,Nemmar A

    更新日期:2020-02-19 00:00:00

  • Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.

    abstract::The present study was performed to evaluate the role of neuronal nitric oxide synthase (nNOS)-derived nitric oxide (NO) during the developmental phase of hypertension in transgenic rats harboring the mouse Ren-2 renin gene (TGR). The first aim of the present study was to examine nNOS mRNA expression in the renal corte...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Cervenka L,Kramer HJ,Malý J,Vanecková I,Bäcker A,Bokemeyer D,Bader M,Ganten D,Mitchell KD

    更新日期:2002-01-01 00:00:00

  • Lymphatic bioavailability of diazepam and desmethyldiazepam in the rat.

    abstract::The lymphatic bioavailability (FL) of diazepam (DZ) and its major metabolite desmethyldiazepam (DDZ) was studied. DZ was administered in intravenous and intraduodenal boluses, and in intravenous infusion in three groups of rats with different total lipid (TL) content in the central lymph. The effect of a) different li...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Lamka J,Jindrová O

    更新日期:1996-01-01 00:00:00

  • Effects of SERCA and PMCA inhibitors on the survival of rat cochlear hair cells during ischemia in vitro.

    abstract::An important mechanism underlying cochlear hair cell (HC) susceptibility to hypoxia/ischemia is the influx of Ca(2+). Two main ATP-dependent mechanisms contribute to maintaining low Ca(2+) levels: uptake of Ca(2+) into intracellular stores via smooth endoplasmic reticulum calcium ATPase (SERCA) and extrusion of Ca(2+)...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Amarjargal N,Mazurek B,Haupt H,Andreeva N,Fuchs J,Gross J

    更新日期:2008-01-01 00:00:00

  • The role of VEGF in the diabetic patients undergoing endovascular therapy of symptomatic aortic valve stenosis.

    abstract::The aim of this study was to explore changes in plasma vascular endothelial growth factor (VEGF) in aged patients who undergone transcatheter aortic valve implantation or balloon angioplasty for the treatment of aortic stenosis. Plasma VEGF was measured in subjects with diabetes mellitus type 2 (DM) (n=21, age 79.2+/-...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932857

    authors: Bláha V,Šťásek J,Bis J,Fortunato J,Andrýs C,Pavlík V,Polanský P,Brtko M,Sobotka L

    更新日期:2014-01-01 00:00:00

  • How to interpret elevated plasmatic level of high-sensitive troponin T in newborns and infants?

    abstract::Research and clinical implications on novel cardiac biomarkers has intensified significantly in the past few years. The high-sensitive troponin T (hscTnT) assay plays a dominant role in diagnostic algorithm regarding myocardial injury in adults. Despite generally accepted use of hscTnT there are no data about physiolo...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.933704

    authors: Jehlicka P,Huml M,Rajdl D,Mockova A,Matas M,Dort J,Masopustova A

    更新日期:2018-05-04 00:00:00

  • Startle stimuli exert opposite effects on human cortical and spinal motor system excitability in leg muscles.

    abstract::Increased excitability of the spinal motor system has been observed after loud and unexpected acoustic stimuli (AS) preceding H-reflexes. The paradigm has been proposed as an electrophysiological marker of reticulospinal tract activity in humans. The brainstem reticular formation also maintains dense anatomical interc...

    journal_title:Physiological research

    pub_type: 杂志文章,随机对照试验

    doi:10.33549/physiolres.932182

    authors: Ilic TV,Pötter-Nerger M,Holler I,Siebner HR,Ilic NV,Deuschl G,Volkmann J

    更新日期:2011-01-01 00:00:00

  • Allosteric activation of yeast enzyme neutral trehalase by calcium and 14-3-3 protein.

    abstract::Neutral trehalase 1 (Nth1) from Saccharomyces cerevisiae catalyzes disaccharide trehalose hydrolysis and helps yeast to survive adverse conditions, such as heat shock, starvation or oxidative stress. 14-3-3 proteins, master regulators of hundreds of partner proteins, participate in many key cellular processes. Nth1 is...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:10.33549/physiolres.933950

    authors: Alblova M,Smidova A,Kalabova D,Lentini Santo D,Obsil T,Obsilova V

    更新日期:2019-04-30 00:00:00

  • Retinoic acid attenuates the mild hyperoxic lung injury in newborn mice.

    abstract::Neonatal exposure to hyperoxia alters lung development in mice. We tested if retinoic acid (RA) treatment is capable to affect lung development after hyperoxic injury and to maintain structural integrity of lung. The gene of vascular endothelial growth factor A (VEGF-A) is one of the RA-responsive genes. Newborn BALB/...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Zimová-Herknerová M,Myslivecek J,Potmesil P

    更新日期:2008-01-01 00:00:00

  • Effects of aging on activities of mitochondrial electron transport chain complexes and oxidative damage in rat heart.

    abstract::Mitochondrial dysfunction and accumulation of oxidative damage have been implicated to be the major factors of aging. However, data on age-related changes in activities of mitochondrial electron transport chain (ETC) complexes remain controversial and molecular mechanisms responsible for ETC dysfunction are still larg...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932019

    authors: Tatarková Z,Kuka S,Račay P,Lehotský J,Dobrota D,Mištuna D,Kaplán P

    更新日期:2011-01-01 00:00:00

  • Serum leptin levels in septic men correlate well with C-reactive protein (CRP) and TNF-alpha but not with BMI.

    abstract::Leptin, an adipocyte-derived signaling factor, is a member of the IL-6 cytokine family. However there is no direct evidence of leptin stimulation of the acute phase protein (APP) synthesis which is typical for all other IL-6-like factors. The purpose of this study was to characterize the dynamics of circulating leptin...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Maruna P,Gürlich R,Frasko R,Haluzík M

    更新日期:2001-01-01 00:00:00

  • Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?

    abstract::Gain-of-function (GOF) mutations in ion channels are rare events, which lead to increased agonist sensitivity or altered gating properties, and may render the channel constitutively active. Uncovering and following characterization of such mutants contribute substantially to the understanding of the molecular basis of...

    journal_title:Physiological research

    pub_type: 杂志文章,评审

    doi:10.33549/physiolres.932658

    authors: Boukalova S,Touska F,Marsakova L,Hynkova A,Sura L,Chvojka S,Dittert I,Vlachova V

    更新日期:2014-01-01 00:00:00

  • Distinct response of fat and gastrointestinal tissue to glucose in gestational diabetes mellitus and polycystic ovary syndrome.

    abstract::Gestational diabetes mellitus (GDM) and polycystic ovary syndrome (PCOS) are distinct pathologies with impaired insulin sensitivity as a common feature. The aim of this study was to evaluate the response of fat tissue adipokines and gastrointestinal incretins to glucose load in patients diagnosed with one of the two d...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.933366

    authors: Vejrazkova D,Lischkova O,Vankova M,Stanicka S,Vrbikova J,Lukasova P,Vcelak J,Vacinova G,Bendlova B

    更新日期:2017-05-04 00:00:00

  • Effect of sialoadenectomy on stomach lesions induced by indomethacin and ethanol in relation to gastric vascular permeability, the gastrin level and HCl secretion in rats.

    abstract::Stomach lesions induced by indomethacin (20 mg.kg-1 i.p.) and ethanol (1 ml 95% intragastrically) were studied after a 24 hour fast in rats which had undergone sialoadenectomy. The size of the lesions was correlated with gastric HCl secretion, with gastric vascular permeability (determined from the Evans blue concentr...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Kohút A,Maheĺová O,Mojzís J,Mirossay L

    更新日期:1992-01-01 00:00:00

  • Noradrenaline reduces cardiovascular effects of the combined dipyridamole and AMP administration but preserves radioprotective effects of these drugs on hematopoiesis in mice.

    abstract::Recent results of the authors have demonstrated that the elevation of extracellular adenosine induced by the combined administration of dipyridamole, a drug inhibiting the cellular uptake of adenosine, and adenosine monophosphate (AMP), a soluble adenosine prodrug, mediates radioprotective effects in mice. Furthermore...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Pospísil M,Hofer M,Vacek A,Netíková J,Pipalová I,Viklická S

    更新日期:1993-01-01 00:00:00

  • MicroRNAs as potential markers of parenteral nutrition associated liver disease in adult patients.

    abstract::Parenteral nutrition-associated liver disease (PNALD) is a severe complication in patients completely dependent on parenteral nutrition (PN). The gold diagnostic standard, liver biopsy, is associated with significant health risk and therefore its use is limited. MicroRNAs (miRNAs) are small non-coding regulatory RNA m...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.934103

    authors: Cahová M,Daňková H,Heczková M,Brátová M,Ďásková N,Baštová H,Gojda J,Wohl P

    更新日期:2019-08-29 00:00:00

  • Effects of lower body negative pressure on cardiac and vascular responses to carotid baroreflex stimulation.

    abstract::The aim of this study was to assess carotid baroreflex responses during graded lower body negative pressure (LBNP). In 12 healthy subjects (age 29+/-4 years) we applied sinusoidal neck suction (0 to -30 mmHg) at 0.1 Hz to examine the sympathetic modulation of the heart and blood vessels and at 0.2 Hz to assess the eff...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:

    authors: Brown CM,Hecht MJ,Neundörfer B,Hilz MJ

    更新日期:2003-01-01 00:00:00

  • Subconvulsive dose of kainic acid transiently increases the locomotor activity of adult Wistar rats.

    abstract::Kainic acid (KA) is a potent neurotoxic substance valuable in research of temporal lobe epilepsy. We tested how subconvulsive dose of KA influences spontaneous behavior of adult Wistar rats. Animals were treated with 5 mg/kg of KA and tested in Laboras open field test for one hour in order to evaluate various behavior...

    journal_title:Physiological research

    pub_type: 杂志文章

    doi:10.33549/physiolres.932793

    authors: Riljak V,Marešová D,Pokorný J,Jandová K

    更新日期:2015-01-01 00:00:00