Abstract：
:Vascular stenosis is often described only by its percentage in both clinical and scientific praxis. Previous studies gave inconclusive results regarding the effect of stenosis eccentricity on its hemodynamic effect. The aim of this experimental study was to investigate and quantify the effect of stenosis severity and eccentricity on the pressure drop. A combination of pressure and flow measurements by Particle Imaging Velocimetry (PIV) method was used. Models of the same stenosis significance but with different levels of eccentricity were studied in vitro by PIV. This study has shown that stenosis asymmetry is associated with more profound pressure drop and flow volume decrease. On the contrary, pressure drop and flow volume decrease were not further significantly influenced by the level of asymmetry. Hemodynamic changes associated with stenosis eccentricity must be taken into account in both clinical and scientific studies.
journal_name
Physiol Resjournal_title
Physiological researchauthors
Novakova L,Kolinsky J,Adamec J,Kudlicka J,Malik Jdoi
10.33549/physiolres.932944subject
Has Abstractpub_date
2016-01-01 00:00:00pages
63-9issue
1eissn
0862-8408issn
1802-9973pii
932944journal_volume
65pub_type
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