In vivo effects of serotonergic agents on alpha-melanocyte-stimulating hormone secretion.

abstract：:The effects of corticotropin-releasing factor (CRF) on GnRH release from the adult male rat mediobasal hypothalamus (MBH) and median eminence (ME) were studied in an in vitro incubation system. CRF induced a dose-related inhibition of GnRH release from both the MBH and the isolated ME, and this inhibition was blocked ...

journal_title：Neuroendocrinology

authors： Gambacciani M,Yen SS,Rasmussen DD

更新日期：1986-01-01 00:00:00

abstract：:Immunoreactive thyroid-stimulating hormone (IR-TSH) has been detected in the hypothalamus and is released in vitro by a calcium-dependent mechanism when the tissue is depolarized. Recently, immunocytochemical studies have revealed that IR-TSH is present in thyrotropes in the pars tuberalis. Therefore, because these th...

journal_title：Neuroendocrinology

authors： De Vito WJ,Connors JM,Hedge GA

更新日期：1985-07-01 00:00:00

abstract：:The effects of GABAa receptor activation on the secretion of alpha-melanocyte-stimulating hormone (alpha-MSH) from the superfused pars intermedia of the amphibian Xenopus laevis were examined. The GABAa receptor agonist isoguvacine inhibited secretion of alpha-MSH from the pars intermedia, an action completely antagon...

journal_title：Neuroendocrinology

authors： Jenks BG,de Koning HP,Valentijn K,Roubos EW

更新日期：1993-07-01 00:00:00

abstract：:Previous studies have shown that the stimulation of LH release by the opiate receptor blocker, naloxone, can be prevented by catecholamine synthesis inhibitors, suggesting opiate regulation of catecholamine release. The present study tested whether an opiate agonist and antagonist would affect the depletion of hypotha...

journal_title：Neuroendocrinology

authors： Adler BA,Crowley WR

更新日期：1984-03-01 00:00:00

abstract：:The effects of angiotensin II (AII) and natriuretic peptide (ANP), alone or in combination, on tuberoinfundibular dopaminergic (TIDA) neuronal activity and on serum PRL levels were examined in this study. The TIDA neuronal activity was determined by measuring 3,4-dihydroxyphenylacetic acid (DOPAC) concentration in the...

journal_title：Neuroendocrinology

authors： Yen SH,Pan JT

更新日期：1997-11-01 00:00:00

abstract：:The developmental pattern of hypophyseal luteinizing hormone (LH) during fetal and early postnatal life, and the capacity of fetal and early postnatal pituitaries to synthesize, release and store LH in the absence of any hypothalamic influence were investigated. Pituitary radioimmunoassayable LH was detectable by feta...

journal_title：Neuroendocrinology

authors： Nemeskéri A,Kurcz M,Halász B

更新日期：1984-05-01 00:00:00

abstract：:The sheep exhibits a marked sex difference in the timing of the pubertal increase in luteinizing hormone (LH). Male lambs undergo a reduction in sensitivity to inhibitory steroid feedback, leading to an increase in LH by 10 weeks of age, but females remain hypersensitive until 30 weeks of age. Endogenous opioids suppr...

journal_title：Neuroendocrinology

authors： Wood RI,I'Anson H,Ebling FJ,Foster DL

更新日期：1992-12-01 00:00:00

abstract：:Galanin-like peptide (GALP) is a 60-amino-acid peptide with structural similarities to galanin and a high affinity for galanin receptors. GALP is expressed by a discrete population of neurons in the arcuate nucleus (ARC) and median eminence of the hypothalamus of several species, including the rat. GALP neurons expres...

journal_title：Neuroendocrinology

authors： Shen J,Gundlach AL

更新日期：2004-01-01 00:00:00

abstract：:The hypothalamic preoptic area (POA) was electrically stimulated through permanently implanted electrodes in 4 unanesthetized sheep. Initiation of POA stimulation was followed witin 10-20 min by large increases in plasma levels of prolactin (PRL). The stimulation-induced discharges of PRL were consistently observed in...

journal_title：Neuroendocrinology

authors： Malven PV

更新日期：1975-01-01 00:00:00

abstract：:These studies investigated the effect of aging on thyroid hormone regulation of beta-endorphin in rat corpus striatum and hypothalamus. In both brain areas, basal levels of beta-endorphin declined with age. In addition, age modified the response of beta-endorphin to thyroid hormone status. Hypothyroid rats aged 6 mont...

journal_title：Neuroendocrinology

authors： Gambert SR

更新日期：1981-02-01 00:00:00

abstract：:Our laboratory has previously described the widespread distribution of an immunoreactive and bioactive rat growth hormone (rGH)-like protein in rat brain. It has also been demonstrated that regulation of pituitary rGH secretion is at least partly mediated by a short-loop negative feedback system. In such a system, inc...

journal_title：Neuroendocrinology

authors： Hojvat S,Emanuele NV,Kirsteins L,Lawrence AM

更新日期：1986-01-01 00:00:00

abstract：:We have studied some of the neuroendocrine and social correlates of dexamethasone resistance in a nonhuman primate population. Subjects were 51 male Macaca fascicularis monkeys with known behavioral histories and who had been given dexamethasone (DEX) suppression tests a week prior to killing. We compared the subset o...

journal_title：Neuroendocrinology

authors： Brooke SM,de Haas-Johnson AM,Kaplan JR,Manuck SB,Sapolsky RM

更新日期：1994-08-01 00:00:00

abstract：:There is a great deal of conflicting data regarding the issue of whether androgens influence opiate receptors in the whole male rat brain. Although Hahn and Fishman initially reported that long-term castration produced a large increase in the density of opiate-binding sites, relative to controls, no other independent ...

journal_title：Neuroendocrinology

authors： Cicero TJ,O'Connor LH,Bell RD

更新日期：1987-08-01 00:00:00

abstract：:A double immunocytochemical procedure, with two different chromogens, was used to compare the respective distribution of estrogen receptor-immunoreactive cells and tyrosine hydroxylase-immunoreactive neurons on the same sections of the preoptic region of adult female rainbow trout (Oncorhynchus mykiss). Estrogen recep...

journal_title：Neuroendocrinology

authors： Linard B,Anglade I,Corio M,Navas JM,Pakdel F,Saligaut C,Kah O

更新日期：1996-02-01 00:00:00

abstract：:Allopregnanolone is a neuroactive steroid present in the brain, but also measurable in systemic circulation. It exhibits anxiolytic and anticonvulsant effects and is able to produce hyperphagia. Since eating behavior disturbances and increased peripheral basal sympathetic activity have been reported in obese subjects,...

journal_title：Neuroendocrinology

authors： Menozzi R,Florio P,Bondi M,Luisi S,Cobellis L,Genazzani AR,Del Rio G,Petraglia F

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Synaptic plasticity is the neuronal capacity to modify the function and structure of dendritic spines (DS) in response to neuromodulators. Sex steroids, particularly 17β-estradiol (E2) and progesterone (P4), are key regulators in the control of DS formation through multiprotein complexes including WAVE1 prot...

journal_title：Neuroendocrinology

authors： Uzair ID,Flamini MI,Sanchez AM

更新日期：2020-01-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:The incidence of obesity is rapidly escalating and has reached epidemic proportions. In all species, including rodents, humans, and sheep, there is large variation in the degree of weight gain across individuals in response to an obesogenic environment. This individual variation is, at least in part, determined by inn...

journal_title：Neuroendocrinology

authors： Henry BA

更新日期：2017-01-01 00:00:00

abstract：:Pituitary transcription factor-1 (Pit-1 or GHF-1) is a transcription factor specific to the anterior pituitary and is involved in the expression and regulation of the growth hormone (GH), prolactin (PRL) and thyroid-stimulating hormone (TSH) beta-subunit genes. The expression of these three genes can be modulated by c...

journal_title：Neuroendocrinology

authors： González-Parra S,Chowen JA,García-Segura LM,Argente J

更新日期：1996-01-01 00:00:00

abstract：:Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more difficult to treat. Some 25% are associated with multiple endocrine neoplasia-1,...

journal_title：Neuroendocrinology

authors： Jia R,Sulentic P,Xu JM,Grossman AB

更新日期：2017-01-01 00:00:00

abstract：:Glucocorticoid hormones have important effects on brain function in the context of acute and chronic stress. Many of these are mediated by the glucocorticoid receptor (GR). GR has transcriptional activity which is highly context-specific and differs between tissues and even between cell types. The outcome of GR-mediat...

journal_title：Neuroendocrinology

authors： Viho EMG,Buurstede JC,Mahfouz A,Koorneef LL,van Weert LTCM,Houtman R,Hunt HJ,Kroon J,Meijer OC

更新日期：2019-01-01 00:00:00

abstract：:The polyphenol curcumin (diferuloylmethane) is the active componenet of the spice plant Curcuma longa and has been shown to exert multiple actions on mammalian cells. We have studied its effect on folliculostellate (FS) TtT/GF mouse pituitary cells, representative of a multifunctional, endocrine inactive cell type of ...

journal_title：Neuroendocrinology

authors： Schaaf C,Shan B,Onofri C,Stalla GK,Arzt E,Schilling T,Perone MJ,Renner U

更新日期：2010-01-01 00:00:00

abstract：:The purpose of the present study was to examine whether repetitive intravenous injections of L-glutamic acid (Glu), like those of N-methyl-D,L-aspartic acid (NMA), are able to elicit a sustained train of gonadotropin releasing hormone (GnRH) discharges from the hypothalamus of the prepubertal male monkey. In order to ...

journal_title：Neuroendocrinology

authors： Medhamurthy R,Gay VL,Plant TM

更新日期：1992-06-01 00:00:00

abstract：:In the present study we utilized the 7315a PRL- and ACTH-secreting tumor to induce a hyperprolactinemic (HP) state sufficient to profoundly suppress the postcastration LH rise in female rats. Tumor-induced prolactin levels which ranged 2,000-3,000 ng/ml substantially reduced the LH rise in both ovariectomized (OVX) an...

journal_title：Neuroendocrinology

authors： Shu C,Selmanoff M

更新日期：1991-09-01 00:00:00

abstract：:The role of endogenous opiate peptides in the mesencephalic central gray (MCG) and their possible interactions with gonadotropin-releasing hormone (GnRH) in the regulation of lordosis behavior was assessed in ovariectomized, estrogen-treated and estrogen-progesterone-treated female rats. Lordosis behavior triggered by...

journal_title：Neuroendocrinology

authors： Sirinathsinghji DJ

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Little information is available concerning prognostic factors for bronchopulmonary large cell neuroendocrine carcinomas (BP-LCNECs) and even less is known about combined LCNECs (Co-LCNECs). We investigated whether an integrated morphological, immunohistochemical, and molecular approach could be used for thei...

journal_title：Neuroendocrinology

authors： Milione M,Maisonneuve P,Grillo F,Mangogna A,Centonze G,Prinzi N,Pusceddu S,Garzone G,Cattaneo L,Busico A,Bossi P,Spaggiari P,Pellegrinelli A,Del Gobbo A,Ferrero S,Kankava K,Pruneri G,Rolli L,Roca E,Bercich L,Tiron

更新日期：2020-05-04 00:00:00

abstract：:Previous studies have shown that prepubertal olfactory bulbectomy will prevent the testicular regression associated with short photoperiod in golden hamsters. The gonadal regression which normally occurs in hamsters on short photoperiod is known to be due in part to an increased responsiveness of the reproductive neur...

journal_title：Neuroendocrinology

authors： Pieper DR,Unthank PD,Shuttie DA,Lobocki CA,Swann JM,Newman S,Subramanian MG

更新日期：1987-10-01 00:00:00

abstract：:The pineal gland in the rat exhibits a diurnal rhythm in activity of the enzyme serotonin N-acetyltransferase (N-AT) with peak values during the dark period of a diurnal lighting schedule approximately 100-fold those during the light period. After blinding the rhythm becomes free-running. It is abolished by partial hy...

journal_title：Neuroendocrinology

authors： Moore RY,Traynor ME

更新日期：1976-01-01 00:00:00

abstract：:The secretion of gonadotropins and the role exerted by the endogenous opioid system on luteinizing hormone (LH) secretion were investigated in 6 postmenopausal women affected by idiopathic Parkinson's disease (PD) as well as in 6 age- and weight-matched normal postmenopausal women as controls. The mean plasma follicle...

journal_title：Neuroendocrinology

authors： Cagnacci A,Melis GB,Soldani R,Bonuccelli U,Piccini P,Napolitano A,Muratorio A,Fioretti P

更新日期：1991-06-01 00:00:00

abstract：:We have previously reported that luteinizing hormone releasing hormone (LH-RH) levels in the medial basal hypothalamus (MBH) of adult male rats castrated for 2 weeks can be raised by testosterone (T) or estradiol (E2) treatment for 3-4 days. The present study was undertaken to determine the time after castration when ...

journal_title：Neuroendocrinology

authors： Kalra PS

更新日期：1985-09-01 00:00:00