Endodermal sinus tumor of the mediastinum.

Abstract:

:Endodermal sinus tumor (EST) of the mediastinum is a rare germ-cell neoplasm affecting mainly young adult males. Ten patients with EST were treated with a multimodality approach that included surgery, chemotherapy, and radiotherapy. All patients had relapses after achieving a transient response except one who is still in complete remission more than five years following the diagnosis of the disease. Optimal therapy for this neoplasm has yet to be discovered. The disease is a subset of extragonadal germ cell tumors which appears to be lethal in most cases, particularly when the primary tumor is unresectable. The first case of five-year disease-free survival is described.

journal_name

Cancer

journal_title

Cancer

authors

Kuzur ME,Cobleigh MA,Greco FA,Einhorn LH,Oldham RK

doi

10.1002/1097-0142(19820815)50:4<766::aid-cncr28205

subject

Has Abstract

pub_date

1982-08-15 00:00:00

pages

766-74

issue

4

eissn

0008-543X

issn

1097-0142

journal_volume

50

pub_type

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