Abstract：
:In order to assess the role of 99mTc-iminodiacetic acid (IDA) cholescintigraphy in evaluating postoperative patients, a total of 213 studies were performed in 189 patients over a 3-year time period. Of these, 130 studies were obtained in 125 cases with signs and/or symptoms suggesting postcholecystectomy syndrome. A normal sized duct that emptied within an hour ruled out significant pathology with a high degree of accuracy (97%). A less reliable finding of normalcy was the combination of ductal dilatation with functional patency in that three of 20 patients (15%) who exhibited this pattern were proven to have nonobstructing calculi in their common bile duct. AZ spectrum of abnormal findings was encountered. Ductal dilatation was a most significant indicator of partial or intermittent ductal obstruction when it was associated with altered time-activity dynamics in the ducts and secondarily, delayed biliary-to-bowel transit time of the radiotracer. Patterns indicating complete common duct obstruction, cystic duct remnants, and bile leaks also proved to be very sensitive. Seventy-three studies in 56 patients very accurately evaluated the integrity of biliary-enteric bypass anastomosis. Complete and partial obstructive patterns were similar in appearance to those encountered in postcholecystectomy syndrome. Several leaks were also detected in this patient population. Ten studies were performed in eight patients who underwent Billroth II gastroenterostomies primarily to see if afferent loop obstruction was present. Three of these patients did demonstrate dilated A-loops with stasis, thereby making a positive diagnosis possible.
journal_name
Semin Nucl Medjournal_title
Seminars in nuclear medicineauthors
Weissmann HS,Gliedman ML,Wilk PJ,Sugarman LA,Badia J,Guglielmo K,Freeman LMdoi
10.1016/s0001-2998(82)80027-5subject
Has Abstractpub_date
1982-01-01 00:00:00pages
27-52issue
1eissn
0001-2998issn
1558-4623pii
S0001-2998(82)80027-5journal_volume
12pub_type
杂志文章,评审abstract：:Uneven distribution of ventilation, or ventilation heterogeneity, has been observed in asthma for over 60 years using multiple breath nitrogen washout (MBNW) studies. Ventilation heterogeneity has been known to predict airway hyperresponsiveness (the ability of the airways to constrict too easily and by too much) in a...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2018.10.007
更新日期：2019-01-01 00:00:00
abstract：:Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigr...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(05)80112-6
更新日期：1993-10-01 00:00:00
abstract：:The basic principles of the use of radiation dosimetry in nuclear medicine are reviewed. The basic structure of the main mathematical equations are given and formal dosimetry systems are discussed. An extensive overview of the history and current status of anthropomorphic models (phantoms) is given. The sources and ma...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2014.03.008
更新日期：2014-05-01 00:00:00
abstract：:This review is directed at the clinically useful highlights of ultrasound and radionuclide testing in adults with coronary and valvular heart disease, intracardiac shunts, and hypertrophic and congestive cardiomyopathies. As a clinical toto, the radionuclide procedures are currently more useful than ultrasound examina...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(80)80031-6
更新日期：1980-01-01 00:00:00
abstract：:Bone scintigraphy of the hands and wrists represents an important adjunct imaging technique that complements plain film radiographic examination. The use of the three-phase bone scan provides clinical information not only regarding osseous uptake but the blood flow and extravascular distribution of the radiotracer as ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(98)80016-0
更新日期：1998-01-01 00:00:00
abstract：:Holmium microspheres have recently become available in the European market as the third type of microspheres for radioembolization of unresectable liver malignancies. Holmium microspheres come with a dedicated administration system, and since these microspheres contain holmium-166 (166Ho) instead of yttrium-90, unique...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2019.01.008
更新日期：2019-05-01 00:00:00
abstract：:The past several years have seen marked advances in technetium/rhenium chemistry applicable to the preparation of new 99mTc-labeled radiopharmaceuticals. This article focuses on recent developments in technetium chemistry, including the preparation of "3 + 1" complexes, the preparation and use of (99mTc[CO]3)+ complex...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/snuc.2001.26182
更新日期：2001-10-01 00:00:00
abstract：:Positron emission tomography (PET) scanning has been a powerful research tool since its inception. Changes in the marketplace that have allowed PET to move into the clinical environment include the commercial availability of appropriate radiopharmaceuticals, reimbursement of procedures by insurance companies, and incr...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1053/snuc.2000.9544
更新日期：2000-10-01 00:00:00
abstract：:Positron emission tomography (PET) makes it possible for the first time to examine in living humans the chemistry of the brain, which relates the structures of the brain to the functions of the mind. PET scans make it possible to assess the state of neurotransmitter receptors, such as the dopamine, serotonin, muscarin...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(86)80004-6
更新日期：1986-01-01 00:00:00
abstract：:The introduction of in vivo imaging of Aβ-amyloid (Αβ) pathology more than a decade ago, transformed the assessment of Alzheimer disease (AD) allowing the evaluation of Aβ deposition over time by providing highly accurate, reliable, and reproducible quantitative statements of regional or global Aβ burden in the brain ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2016.09.006
更新日期：2017-01-01 00:00:00
abstract：:FDG is a tracer for visualizing glucose metabolism. PET/CT using FDG is widely used for the diagnosis of cancer, because glycolysis is elevated in cancer cells. Similarly, active inflammatory tissue also exhibits elevated glucose metabolism because of glycolysis in activated macrophages and proliferating fibroblasts. ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2017.02.005
更新日期：2017-07-01 00:00:00
abstract：:Suspecting and diagnosing venous thrombosis and pulmonary embolism remain major clinical problems. For a variety of reasons, including the patient's pre-existing cardiac and pulmonary status and the release of humoral mediators, pulmonary emboli evoke varied responses in different patients. Symptoms and signs of pulmo...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(05)80131-x
更新日期：1991-10-01 00:00:00
abstract：:Recently, the lung has received increasing attention as a metabolic organ. In this role, the lung modulates the composition of the arterial blood by several mechanisms: removing active substances from the plasma, releasing substances into the plasma, temporarily holding substances from circulation, and activating or i...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(86)80016-2
更新日期：1986-10-01 00:00:00
abstract：:Patients with previously treated thyroid carcinoma require lifelong monitoring for recurrent disease. Two diagnostic tests that play a central role in follow-up of these patients--radioiodine whole body scanning and serum thyroglobulin measurement--are most accurate during thyroid-stimulating hormone (TSH) stimulation...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/nm.2000.4599
更新日期：2000-04-01 00:00:00
abstract：:Assessment of regional cerebral blood flow (rCBF) is useful in the evaluation of cerebral vascular disease. However, a single resting study has limitations in that a normal rCBF may be present with diminished cerebral vascular flow reserve and regions of decreased rCBF may be seen with diaschisis or selective neuronal...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(05)80052-2
更新日期：1991-04-01 00:00:00
abstract：:The short range and high linear energy transfer of α-particles offer the potential for efficient tumor killing while sparing normal bystander cells. Hematologic malignancies are ideally suited to targeted α-particle therapy (TAT) due to easy accessibility of malignant cells in blood, bone marrow, lymph nodes, and sple...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2019.09.002
更新日期：2020-03-01 00:00:00
abstract：:(18)F-fluorodeoxyglucose (FDG) is the radiotracer used in the vast majority of positron emission tomography (PET) cancer studies. FDG is a powerful radiotracer that provides valuable data in many cancer types. Normal FDG biodistribution is easily identified. In the PET-only era, physiological uptake provided important...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2010.02.001
更新日期：2010-07-01 00:00:00
abstract：:In the last few years there has been a remarkable increase in the amount of clinical data in the average hospital chart, and more and more problem-solving algorithms have been developed. We need better "thinking tools" to help us handle the flow of information. The term "clinical decision making" is used to describe a...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1053/j.semnuclmed.2010.05.001
更新日期：2010-09-01 00:00:00
abstract：:Computer processing can improve the quality of scintigrams in several ways. It can increase the accuracy with which the image approximates the activity distribution by reversing degradation. It can selectively enhance normal or abnormal structures of interest. It can optimize the use of the display system presenting t...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(78)80036-1
更新日期：1978-04-01 00:00:00
abstract：:The increasing use of automated blood chemistry screens for serum calcium levels along with improved methods in measuring parathyroid hormone (PTH) levels have made the diagnosis of parathyroid disease a common clinical problem. Parathyroid adenomas account for the majority of primary hyperparathyroidism with diffuse ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(85)80024-6
更新日期：1985-04-01 00:00:00
abstract：:Although electronic imaging was performed in the early 1950s in nuclear medicine, it was the introduction of computed tomography in 1972 that caused a revolution in medical imaging in that it marked the beginning of the inevitable transformation to digital imaging. This transformation is now more or less complete. Whi...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2018.11.010
更新日期：2019-03-01 00:00:00
abstract：:Bone metastases are associated with increased morbidity and poor prognosis in castration-resistant prostate cancer. Since 2010, 5 systemic therapies for metastatic castration-resistant prostate cancer have been approved by the US Food and Drug Administration based on an improvement in overall survival, offering altern...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2014.07.006
更新日期：2015-01-01 00:00:00
abstract：:Molecular imaging has revolutionized clinical oncology by imaging-specific facets of cancer biology. Through noninvasive measurements of tumor physiology, targeted radiotracers can serve as biomarkers for disease characterization, prognosis, response assessment, and predicting long-term response/survival. In turn, the...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2020.07.002
更新日期：2020-11-01 00:00:00
abstract：:Tc-99m pyrophosphate is the grandfather of infarct avid agents. Its value is its clinical availability and ease of use. However, its shortcomings are the delay of 2 to 3 days for reliable interpretation in nonreperfused myocardial infarction (MI) and the overarching bone activity. Antimyosin provides exquisite specifi...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(99)80014-2
更新日期：1999-07-01 00:00:00
abstract：:Concern about the spread of infections in the hospital setting has prompted regulatory agencies to mandate infection control standards. Each hospital department is required to have written policies and procedures which describe measures to prevent and control the spread of nosocomial infections (hospital acquired infe...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(88)80043-6
更新日期：1988-10-01 00:00:00
abstract：:Prospective delineation of viable from nonviable myocardium in patients with coronary artery disease in an important factor in deciding whether a patient should be revascularized or treated medically. Two common techniques--single-photon emission computed tomography (SPECT) and positron-emission computed tomography (P...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(96)80007-9
更新日期：1996-10-01 00:00:00
abstract：:New software methods that incorporate iterative reconstruction, resolution recovery, and noise compensation now provide the ability to maintain or improve myocardial perfusion SPECT image quality with conventional sodium iodide cameras. Despite lower image counting statistics associated with significantly decreased in...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2014.04.001
更新日期：2014-07-01 00:00:00
abstract：:Nuclear dacryocystography is simple, relatively harmless method of evaluating patients suspected of having abnormalities of the nasolacrimal drainage system. A group of normal saline containing approximately 100 muCi of 99mTc-pertechnetate is placed on the conjunctiva near the lateral canthus, and serial scintigrams a...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(81)80022-0
更新日期：1981-10-01 00:00:00
abstract：:The accumulation of radioactive tracer is associated with specific histological changes. Awareness of these changes permits a more specific interpretation of a positive bone scan, especially when correlating the radionuclide image with the plain radiographs. Increased uptake in the flow phase of an imaging study usual...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(97)80003-7
更新日期：1997-10-01 00:00:00
abstract：:Positron emission tomography (PET) using the radiotracer 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) can image cellular proliferation in human cancers in vivo. FLT uptake has been shown to correlate with pathology-based proliferation measurements, including the Ki-67 score, in a variety of human cancers. Unlike pathology...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2007.08.001
更新日期：2007-11-01 00:00:00
