Abstract：
:Bone scintigraphy of the hands and wrists represents an important adjunct imaging technique that complements plain film radiographic examination. The use of the three-phase bone scan provides clinical information not only regarding osseous uptake but the blood flow and extravascular distribution of the radiotracer as well. Scintigraphic evaluation of the hands and wrists is employed in acute and chronic conditions. In the event of an equivocal or negative plain film, the bone scan can identify occult fractures. Of particular concern is the identification of scaphoid fractures due to the higher incidence of osteonecrosis. Work related injuries represent a significant health issue. The bone scan can be a part of the algorithm for evaluating chronic pain syndromes including reflex sympathetic dystrophy. The complimentary roles of bone scanning and imaging with gallium-67 citrate or radiolabeled leukocytes has proven useful in the evaluation of acute or chronic osteomyelitis. In addition, the diphosphonates are useful in identifying solitary and multiple primary bone tumors. In the case of primary bone tumor, thallium-201 can be used to evaluate response to therapy. Although uncommon in the hand and wrist, the bone scan can identify metastatic tumors or tumor-related conditions such as hypertrophic osteoarthropathy. Finally, bone scintigraphy may be useful in identifying location and extent in a variety of conditions such as fibrous dysplasia, histiocytosis X, and Paget's disease.
journal_name
Semin Nucl Medjournal_title
Seminars in nuclear medicineauthors
Vande Streek P,Carretta RF,Weiland FL,Shelton DKdoi
10.1016/s0001-2998(98)80016-0subject
Has Abstractpub_date
1998-01-01 00:00:00pages
14-24issue
1eissn
0001-2998issn
1558-4623pii
S0001-2998(98)80016-0journal_volume
28pub_type
杂志文章,评审abstract：:Myocardial perfusion imaging with 15O-water positron emission tomography (PET) is a validated tool for quantitative measurement of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Current scanner and software technology enable quantification of global and regional MBF in clinical PET myocardial perfusion...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2020.02.011
更新日期：2020-05-01 00:00:00
abstract：:Computer processing can improve the quality of scintigrams in several ways. It can increase the accuracy with which the image approximates the activity distribution by reversing degradation. It can selectively enhance normal or abnormal structures of interest. It can optimize the use of the display system presenting t...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(78)80036-1
更新日期：1978-04-01 00:00:00
abstract：:While 99mTc sulfur colloid imaging, because of its availability and convenience, remains the initial procedure of choice for spleen imaging, selective spleen scanning with damaged 99mTc-labeled RBCs can provide additional information in some cases. These cases include overlapping left hepatic lobe and suspected spleni...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(85)80004-0
更新日期：1985-07-01 00:00:00
abstract：:Tc-99m pyrophosphate is the grandfather of infarct avid agents. Its value is its clinical availability and ease of use. However, its shortcomings are the delay of 2 to 3 days for reliable interpretation in nonreperfused myocardial infarction (MI) and the overarching bone activity. Antimyosin provides exquisite specifi...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(99)80014-2
更新日期：1999-07-01 00:00:00
abstract：:Several antineuroblastoma monoclonal antibodies (MoAbs) have been described and two have been used in radioimmunoimaging and radioimmunotherapy in patients. MoAb 3F8 is a murine IgG3 antibody specific for the ganglioside GD2. Radioiodine-labeled 3F8 has been shown to specifically target human neuroblastoma in patients...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(89)80021-2
更新日期：1989-10-01 00:00:00
abstract：:Up to 25% of the diabetic population is at risk for developing a pedal ulcer. These ulcers serve as a portal of entry for osteomyelitis and overlie more than 90% of diabetic pedal osteomyelitis cases. The diagnosis of osteomyelitis often is overlooked, and imaging studies are an essential part of the evaluation. The m...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2008.08.006
更新日期：2009-01-01 00:00:00
abstract：:In the last few years there has been a remarkable increase in the amount of clinical data in the average hospital chart, and more and more problem-solving algorithms have been developed. We need better "thinking tools" to help us handle the flow of information. The term "clinical decision making" is used to describe a...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1053/j.semnuclmed.2010.05.001
更新日期：2010-09-01 00:00:00
abstract：:Concern about the spread of infections in the hospital setting has prompted regulatory agencies to mandate infection control standards. Each hospital department is required to have written policies and procedures which describe measures to prevent and control the spread of nosocomial infections (hospital acquired infe...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(88)80043-6
更新日期：1988-10-01 00:00:00
abstract：:Monoclonal antibody (MoAb) imaging has contributed greatly to the diagnosis and staging of both colorectal and ovarian cancers, and recently has been tested in patients with prostate cancer. Anatomic imaging modalities such as computed tomography, ultrasound, and magnetic resonance imaging have deficiencies in imaging...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(05)80019-4
更新日期：1994-10-01 00:00:00
abstract：:The process of discovering and developing a new pharmaceutical is a long, difficult, and risky process that requires numerous resources. Molecular imaging techniques such as PET have recently become a useful tool for making decisions along a drug candidate's development timeline. PET is a translational, noninvasive im...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2017.05.006
更新日期：2017-09-01 00:00:00
abstract：:The increasing use of automated blood chemistry screens for serum calcium levels along with improved methods in measuring parathyroid hormone (PTH) levels have made the diagnosis of parathyroid disease a common clinical problem. Parathyroid adenomas account for the majority of primary hyperparathyroidism with diffuse ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(85)80024-6
更新日期：1985-04-01 00:00:00
abstract：:The practice of nuclear medicine in children is well established for imaging practically all physiologic systems but particularly in the fields of oncology, neurology, urology, and orthopedics. Pediatric nuclear medicine yields images of physiologic and molecular processes that can provide essential diagnostic informa...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2016.10.006
更新日期：2017-03-01 00:00:00
abstract：:Autonomic innervation plays an important role in proper functioning of the cardiovascular system. Altered cardiac sympathetic function is present in a variety of diseases, and can be assessed with radionuclide imaging using sympathetic neurotransmitter analogues. The most studied adrenergic radiotracer is cardiac 123I...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2020.03.001
更新日期：2020-07-01 00:00:00
abstract：:The radioimmunoassay of digoxin is one of the most important services of the nuclear medicine laboratory. Precision and accuracy in the performance of the test are especially critical. A number of commerical kits are available and reliable. Pitfalls to be avoided includelimited availability or delay in performance of ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(75)80010-9
更新日期：1975-07-01 00:00:00
abstract：:This review describes general concepts with regard to radiopharmaceuticals for diagnostic or therapeutic applications that help to understand the specific challenges encountered during the design, (radio)synthesis, in vitro and in vivo evaluation and clinical translation of novel radiopharmaceuticals. The design of a ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2019.07.001
更新日期：2019-09-01 00:00:00
abstract：:Detection of acute myocardial infarction as an area of increased activity has intrigued investigators for some time. Initial attempts with 203Hg-chlormerodrin and 203Hg-fluorescein analogues were successful in man. More recently, however, successful imaging of the acute myocardial infarct has been achieved with severa...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(77)80005-6
更新日期：1977-01-01 00:00:00
abstract：:The diphosphonate bone scan is ideally suited to assess many global, focal or multifocal metabolic bone disorders and there remains a role for conventional bone scintigraphy in metabolic bone disorders at diagnosis, investigation of complications, and treatment response assessment. In contrast, the role of bone scinti...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2009.08.002
更新日期：2010-01-01 00:00:00
abstract：:Nuclear dacryocystography is simple, relatively harmless method of evaluating patients suspected of having abnormalities of the nasolacrimal drainage system. A group of normal saline containing approximately 100 muCi of 99mTc-pertechnetate is placed on the conjunctiva near the lateral canthus, and serial scintigrams a...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(81)80022-0
更新日期：1981-10-01 00:00:00
abstract：:Radionuclide renal studies are particularly well suited to pediatrics as renal problems in children usually are part of a dynamic process which requires serial assessment. The absence of side-effects and the low radiation dose has added to their popularity in pediatrics. A number of different renal parameters can be e...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(82)80015-9
更新日期：1982-10-01 00:00:00
abstract：:Radioimmunotherapy is a form of targeted radionuclide therapy that uses a monoclonal antibody to deliver localized radiation. It is most appropriate for treatment of multiple tumor sites that cannot be readily excised surgically or irradiated using external beam radiation or brachytherapy. At present, 2 products, Bexx...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2009.11.002
更新日期：2010-03-01 00:00:00
abstract：:Identification of patients with renovascular hypertension (RVH) among the larger group of patients with essential hypertension has been aided by a wide variety of in vitro and in vivo nuclear medicine procedures. The most valuable in vitro procedure remains the radioimmunoassay (RIA) for renin activity obtained from i...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(89)80005-4
更新日期：1989-04-01 00:00:00
abstract：:Breast cancer is the most common cause of bone metastases in women. Imaging studies are useful to identify bone involvement and associated complications, for follow-up of disease spread and for the assessment of response to therapy. Bone scintigraphy with (99m)technetium-labeled diphosphonates is most widely used, due...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2009.05.002
更新日期：2009-11-01 00:00:00
abstract：:Compared with planar imaging, ventilation/perfusion scintigraphy performed with single-photon emission computed tomography (SPECT) has a greater sensitivity and specificity, greater accuracy, improved reproducibility, and a lower number of inconclusive reports in the detection of pulmonary embolism. Despite these impr...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2010.07.004
更新日期：2010-11-01 00:00:00
abstract：:Computer tomography (CT) is a radiological imaging method which yields transverse tomographic images reflecting with high accuracy the spatial distribution of x-ray attenuation in the part examined. The contrast resolution achieved by CT permits the visualization of soft tissue structure heretofore invisible with conv...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章
doi：10.1016/s0001-2998(77)80013-5
更新日期：1977-04-01 00:00:00
abstract：:The use of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in prostate cancer depends on the phase of the disease along the natural history of this prevalent malignancy in men. Incidental high FDG uptake in the prostate gland, although rare, should prompt further investigation with at least a meas...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2016.07.004
更新日期：2016-11-01 00:00:00
abstract：:The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s. Today, despite the many advances in imaging instrumentation, radiopharmaceuticals, and methodology over these years, cholescintigraphy still plays an important role in confirming or excl...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(03)00032-1
更新日期：2003-10-01 00:00:00
abstract：:Regional cerebral blood flow (rCBF) findings and their application to cerebrovascular disease are reviewed. Although the coupling of cerebral blood flow and metabolism are best studied with positron emission tomography, single-photon emission computed tomography measurements of rCBF can contribute to patient managemen...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(05)80236-3
更新日期：1990-10-01 00:00:00
abstract：:Prospective delineation of viable from nonviable myocardium in patients with coronary artery disease in an important factor in deciding whether a patient should be revascularized or treated medically. Two common techniques--single-photon emission computed tomography (SPECT) and positron-emission computed tomography (P...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1016/s0001-2998(96)80007-9
更新日期：1996-10-01 00:00:00
abstract：:Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2016.04.002
更新日期：2016-09-01 00:00:00
abstract：:Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are now more and more available for clinical use. PET/MR combines the unique features of MR including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as we...
journal_title：Seminars in nuclear medicine
pub_type： 杂志文章,评审
doi：10.1053/j.semnuclmed.2018.02.003
更新日期：2018-05-01 00:00:00
