Abstract:
:Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigraphic approach defines the components of the lymphatic and vascular systems with the use of technetium-99m [99mTc] antimony sulfide colloid (99mTc Sb2S3) for lymphatic, 99mTc diethylenetriamine pentacetic acid (DTPA) for capillary-interstitial, and 99mTc-tagged red blood cells for venous systems.
journal_name
Semin Nucl Medjournal_title
Seminars in nuclear medicineauthors
Mandell GA,Alexander MA,Harcke HTdoi
10.1016/s0001-2998(05)80112-6subject
Has Abstractpub_date
1993-10-01 00:00:00pages
334-46issue
4eissn
0001-2998issn
1558-4623pii
S0001-2998(05)80112-6journal_volume
23pub_type
杂志文章,评审abstract::In the past, T3 suppression testing was often required to confirm the presence of autonomous thyroid function in patients with borderline clinical and laboratory findings suggestive of hyperthyroidism or in euthyroid patients with the stigmata of Graves' disease. Similarly, TSH stimulation testing was used to document...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(81)80043-8
更新日期:1981-04-01 00:00:00
abstract::The remarkable progress in immunologic techniques in the development of monoclonal antibodies offers the potential for powerful new tools for the detection of cardiovascular disorders, such as acute myocardial necrosis and acute deep venous thrombosis, in an accurate, safe, and noninvasive manner. Historically the use...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80094-7
更新日期:1993-04-01 00:00:00
abstract::We describe our all-digital, filmless, department of nuclear medicine, which has been fully operational for 3 years. The approach to the design and implementation of a nuclear medicine picture archiving and communication system (PACS) is discussed, as well as enhancements found to be necessary or desirable during our ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(05)80031-5
更新日期:1990-07-01 00:00:00
abstract::The advent of simultaneous PET/MRI brought a large amount of possibilities in research and clinical applications into hybrid imaging. Unlike in PET/CT protocols, the MR component provides an almost unlimited number of pulse sequences and possibilities of different protocols in PET/MRI. Nevertheless, there is an impera...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2015.03.007
更新日期:2015-07-01 00:00:00
abstract::Although planar radionuclide techniques provide accurate, noninvasive measurements of myocardial perfusion and function that are of proven clinical value in the evaluation of the cardiac patient, they are limited by poor object contrast and superimposition of surrounding structures. Due to incomplete angular sampling ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(87)80034-x
更新日期:1987-07-01 00:00:00
abstract::The use of gallium for pulmonary diseases is hampered by its relative lack of specificity, typical 1- to 3-day delay between injection and imaging time, and suboptimal imaging characteristics. Other nuclear and nonnuclear imaging modalities, such as (18)F-fluorodeoxyglucose positron emission tomography (PET) and high-...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/snuc.2002.124178
更新日期:2002-07-01 00:00:00
abstract::Neurochemical imaging is one of the most established "molecular" imaging techniques. There have been tremendous efforts expended to develop radioligands specific to each neurochemical system. Investigational applications of neurochemical imaging in dementing disorders are extensive. Cholinergic, dopaminergic, and sero...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2003.09.008
更新日期:2004-01-01 00:00:00
abstract::Holmium microspheres have recently become available in the European market as the third type of microspheres for radioembolization of unresectable liver malignancies. Holmium microspheres come with a dedicated administration system, and since these microspheres contain holmium-166 (166Ho) instead of yttrium-90, unique...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2019.01.008
更新日期:2019-05-01 00:00:00
abstract::Evaluation of ventricular performance is essential in the diagnosis and long-term management of patients with heart disease. This can be most easily performed clinically using simple tools. When more definitive objective assessment of cardiac function is indicated, the equilibrium gated blood pool study provides relia...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(79)80015-x
更新日期:1979-10-01 00:00:00
abstract::The results of quantitative analysis of planar thallium-201 stress scintigraphy are superior to those of visual analysis. The increased sensitivity for detection of coronary artery disease is associated with maintenance of specificity. Consequently, we believe that quantitative analysis is the state-of-the-art for pla...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(85)80043-x
更新日期:1985-01-01 00:00:00
abstract::Assessment of regional cerebral blood flow (rCBF) is useful in the evaluation of cerebral vascular disease. However, a single resting study has limitations in that a normal rCBF may be present with diminished cerebral vascular flow reserve and regions of decreased rCBF may be seen with diaschisis or selective neuronal...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80052-2
更新日期:1991-04-01 00:00:00
abstract::The radionuclide (99m)Tc-MDP bone scan is one of the most commonly performed nuclear medicine studies and helps in the diagnosis of different pathologies relating to the musculoskeletal system. With its increasing utility in clinical practice, it becomes more important to be aware of various limitations of this imagin...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2015.02.002
更新日期:2015-09-01 00:00:00
abstract::In the early 1970s, when Seminars in Nuclear Medicine started publication, little was known about the quality of reporting in biomedical journals. Senior scholars were invited to become scientific editors of journals based on their research credibility and stature. Their knowledge of journalology (publication science)...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2018.11.009
更新日期:2019-03-01 00:00:00
abstract::This review summarizes the role of SPECT/CT in patients with a painful postoperative knee and describes typical diagnostic criteria in these patients. Pain after knee surgery is common and is influenced by the underlying pathology, the type of surgery, and the patient. Knee joint-preserving surgery includes osteotomy,...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2018.05.003
更新日期:2018-09-01 00:00:00
abstract::Epilepsy is the most common serious brain disorder in children, occurring in all parts of the world and within every stratum of the population. Through its effects, it exerts a significant physical, psychological, economic, and social toll on children and their caregivers. Historically, the surgical treatment of epile...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2012.06.005
更新日期:2012-11-01 00:00:00
abstract::The short range and high linear energy transfer of α-particles offer the potential for efficient tumor killing while sparing normal bystander cells. Hematologic malignancies are ideally suited to targeted α-particle therapy (TAT) due to easy accessibility of malignant cells in blood, bone marrow, lymph nodes, and sple...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2019.09.002
更新日期:2020-03-01 00:00:00
abstract::Suspecting and diagnosing venous thrombosis and pulmonary embolism remain major clinical problems. For a variety of reasons, including the patient's pre-existing cardiac and pulmonary status and the release of humoral mediators, pulmonary emboli evoke varied responses in different patients. Symptoms and signs of pulmo...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80131-x
更新日期:1991-10-01 00:00:00
abstract::Blood cell labeling with 99mTc has progressed through various developmental phases. In the case of red cell labeling, the science seems to have matured sufficiently, although minor refinements in the procedures will no doubt continue to be made. During the last 3 to 5 years, there has been a resurgence of interest in ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80175-8
更新日期:1990-01-01 00:00:00
abstract::In epilepsy, a detailed history, blood chemistry, routine electroencephalography, and brain MRI are important for the diagnosis of seizure type or epilepsy syndrome for the decision of appropriate drug treatment. Although antiepileptic drugs are mostly successful for controlling epileptic seizures, 20%-30% patients ar...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2016.01.003
更新日期:2016-07-01 00:00:00
abstract::In the last few years there has been a remarkable increase in the amount of clinical data in the average hospital chart, and more and more problem-solving algorithms have been developed. We need better "thinking tools" to help us handle the flow of information. The term "clinical decision making" is used to describe a...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1053/j.semnuclmed.2010.05.001
更新日期:2010-09-01 00:00:00
abstract::Molecular medicine enhances the clinician's ability to accurately diagnose and treat disease, and many technological advances in diverse fields have made the translation of molecular medicine to the clinic possible. Nuclear medicine encompasses 2 technologies--single-photon emission computed tomography (SPECT) and pos...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2008.01.004
更新日期:2008-05-01 00:00:00
abstract::Much efficacy is gained in clinical practice if a single agent can be used for both diagnosis and therapy, a practice termed theranostics. Metaiodobenzylguanidine (mIBG), a norepinephrine analogue with high sensitivity and specificity for neuroblastoma, is an exemplar of theranostics. The physiologic biodistribution o...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2016.02.002
更新日期:2016-05-01 00:00:00
abstract::2-deoxy-2-[18F] fluoro-D-glucose (18FDG) was developed in 1976 in a collaboration between scientists at the National Institutes of Health, the University of Pennsylvania, and Brookhaven National Laboratory. It was developed for the specific purpose of mapping brain glucose metabolism in living humans, thereby serving ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/snuc.2002.29270
更新日期:2002-01-01 00:00:00
abstract::Radionuclide angiocardiography and myocardial perfusion imaging with exercise are valuable methods to assess patients undergoing percutaneous transluminal coronary angioplasty. Successful angioplasty results in improvement in ventricular systolic and diastolic function and regional perfusion. Complications of angiopla...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80048-0
更新日期:1991-04-01 00:00:00
abstract::Nuclear medicine imaging techniques continue to play a unique role in the evaluation of hepatic masses. Although many useful radiodiagnostic agents are available, the predominant nuclear medicine study used to evaluate hepatic masses in this decade is technetium-labeled red blood cell "blood-pool" scintigraphy. Hepati...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(96)80012-2
更新日期:1996-01-01 00:00:00
abstract::In this work, the methods of the Prospective Investigation of Pulmonary Embolism Diagnosis III (PIOPED III) are described in detail. PIOPED III is a multicenter collaborative investigation sponsored by the National Heart, Lung and Blood Institute. The purpose is to determine the accuracy of gadolinium-enhanced magneti...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,多中心研究,评审
doi:10.1053/j.semnuclmed.2008.06.003
更新日期:2008-11-01 00:00:00
abstract::Depending on the iodine supply of an area, the incidence of thyroid cancer ranges between 4 and 12/100,000 per year. To detect thyroid cancer in an early stage, the assessment of thyroid nodules includes ultrasonography, ultrasonography-guided fine-needle aspiration biopsy, and conventional scintigraphic methods using...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2006.03.002
更新日期:2006-07-01 00:00:00
abstract::This review describes the use of monoclonal antibodies (MoAbs) for immunoscintigraphic detection of thrombosis and thromboembolism. Two major groups of MoAbs have been tested: Antibodies directed against platelets and antibodies directed against fibrin. Several antiplatelet antibodies have been developed that are dire...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(89)80015-7
更新日期:1989-07-01 00:00:00
abstract::Myocardial perfusion imaging with 15O-water positron emission tomography (PET) is a validated tool for quantitative measurement of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Current scanner and software technology enable quantification of global and regional MBF in clinical PET myocardial perfusion...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2020.02.011
更新日期:2020-05-01 00:00:00
abstract::Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2016.04.002
更新日期:2016-09-01 00:00:00