Advances in the diagnosis and treatment of epilepsy.

abstract：:Radioimmunotherapy is a form of targeted radionuclide therapy that uses a monoclonal antibody to deliver localized radiation. It is most appropriate for treatment of multiple tumor sites that cannot be readily excised surgically or irradiated using external beam radiation or brachytherapy. At present, 2 products, Bexx...

journal_title：Seminars in nuclear medicine

authors： Goldsmith SJ

更新日期：2010-03-01 00:00:00

abstract：:Bone scintigraphy of the hands and wrists represents an important adjunct imaging technique that complements plain film radiographic examination. The use of the three-phase bone scan provides clinical information not only regarding osseous uptake but the blood flow and extravascular distribution of the radiotracer as ...

journal_title：Seminars in nuclear medicine

authors： Vande Streek P,Carretta RF,Weiland FL,Shelton DK

更新日期：1998-01-01 00:00:00

abstract：:Prostate cancer (PCa) is one of the most common cancers in men and is the second leading cause of cancer-related deaths in the USA. In the United States, it is the second most frequently diagnosed cancer after skin cancer, and in Europe it is number one. According to the American Cancer Society, approximately 221,000 ...

journal_title：Seminars in nuclear medicine

authors： Evans-Axelsson S,Timmermand OV,Bjartell A,Strand SE,Elgqvist J

更新日期：2016-03-01 00:00:00

abstract：:Heart transplantation is an effective and life-saving therapy for patients with end-stage heart disease. Cardiac allograft vasculopathy (CAV) is a frequent complication after heart transplantation and a leading cause of graft failure and death. The diffuse involvement of the coronary macro- and microvasculature in CAV...

journal_title：Seminars in nuclear medicine

authors： Chih S,Wiefels CC,Beanlands RSB

更新日期：2021-01-19 00:00:00

abstract：:The introduction of in vivo imaging of Aβ-amyloid (Αβ) pathology more than a decade ago, transformed the assessment of Alzheimer disease (AD) allowing the evaluation of Aβ deposition over time by providing highly accurate, reliable, and reproducible quantitative statements of regional or global Aβ burden in the brain ...

journal_title：Seminars in nuclear medicine

authors： Villemagne VL,Doré V,Bourgeat P,Burnham SC,Laws S,Salvado O,Masters CL,Rowe CC

更新日期：2017-01-01 00:00:00

abstract：:Breast cancer is the most common cause of bone metastases in women. Imaging studies are useful to identify bone involvement and associated complications, for follow-up of disease spread and for the assessment of response to therapy. Bone scintigraphy with (99m)technetium-labeled diphosphonates is most widely used, due...

journal_title：Seminars in nuclear medicine

authors： Ben-Haim S,Israel O

更新日期：2009-11-01 00:00:00

abstract：:The advantage of immunoscintigraphy over autologous leukocyte techniques in the imaging of infection is the simplicity of its use compared with techniques that require the isolation of autologous white blood cells. The advantage over 99mTc- or 111In-labeled nonspecific human immunoglobulin is the excellent target-to-b...

journal_title：Seminars in nuclear medicine

authors： Becker W,Goldenberg DM,Wolf F

更新日期：1994-04-01 00:00:00

abstract：:The objective of this work is to compare the characteristics of various techniques for functional renal imaging, with a focus on nuclear medicine and magnetic resonance imaging. Even with low spatial resolution and rather poor signal-to-noise ratio, classical nuclear medicine has the advantage of linearity and good se...

journal_title：Seminars in nuclear medicine

authors： Durand E,Chaumet-Riffaud P,Grenier N

更新日期：2011-01-01 00:00:00

abstract：:Bone metastases are associated with increased morbidity and poor prognosis in castration-resistant prostate cancer. Since 2010, 5 systemic therapies for metastatic castration-resistant prostate cancer have been approved by the US Food and Drug Administration based on an improvement in overall survival, offering altern...

journal_title：Seminars in nuclear medicine

authors： Abi-Ghanem AS,McGrath MA,Jacene HA

更新日期：2015-01-01 00:00:00

abstract：:Suspecting and diagnosing venous thrombosis and pulmonary embolism remain major clinical problems. For a variety of reasons, including the patient's pre-existing cardiac and pulmonary status and the release of humoral mediators, pulmonary emboli evoke varied responses in different patients. Symptoms and signs of pulmo...

journal_title：Seminars in nuclear medicine

authors： Palevsky HI

更新日期：1991-10-01 00:00:00

abstract：:The practice of nuclear medicine in children is well established for imaging practically all physiologic systems but particularly in the fields of oncology, neurology, urology, and orthopedics. Pediatric nuclear medicine yields images of physiologic and molecular processes that can provide essential diagnostic informa...

journal_title：Seminars in nuclear medicine

authors： Fahey FH,Goodkind AB,Plyku D,Khamwan K,O'Reilly SE,Cao X,Frey EC,Li Y,Bolch WE,Sgouros G,Treves ST

更新日期：2017-03-01 00:00:00

abstract：:There seems little doubt that the ability to prepare antibodies with a unique specificity for surface tumor antigens will have a tremendous usefulness in the diagnostic and therapeutics of cancer. This usefulness will be wide-ranged when the antibodies are labeled with radioisotopes as tools for screening for primary ...

journal_title：Seminars in nuclear medicine

authors： Spar IL

更新日期：1976-10-01 00:00:00

abstract：:Lymphomas represent a diverse range of diseases with manifold presentations, outlook, and therapeutic approaches. Key to the modern management of lymphoma is accurate delineation of the extent of disease. The inability of computed tomography (CT) to identify the involvement of nonenlarged nodes and its relatively poor...

journal_title：Seminars in nuclear medicine

authors： Hicks RJ,Mac Manus MP,Seymour JF

更新日期：2005-07-01 00:00:00

abstract：:The role of labeled tracers in radioimmunoassay procedures (RIA) and the advantages of the iodine-labeled antigens over 14C or tritium-labeled antigens are discussed. Different methods of labeling with iodine isotopes are presented. The ease with which microgram amounts of hormonal proteins are tagged, achieving high...

journal_title：Seminars in nuclear medicine

authors： Chervu LR,Murty DR

更新日期：1975-04-01 00:00:00

abstract：:Positron emission tomography (PET) makes it possible for the first time to examine in living humans the chemistry of the brain, which relates the structures of the brain to the functions of the mind. PET scans make it possible to assess the state of neurotransmitter receptors, such as the dopamine, serotonin, muscarin...

journal_title：Seminars in nuclear medicine

authors： Wagner HN Jr

更新日期：1986-01-01 00:00:00

abstract：:Concern about the spread of infections in the hospital setting has prompted regulatory agencies to mandate infection control standards. Each hospital department is required to have written policies and procedures which describe measures to prevent and control the spread of nosocomial infections (hospital acquired infe...

journal_title：Seminars in nuclear medicine

authors： Adams A,Egan A

更新日期：1988-10-01 00:00:00

abstract：:Heart failure presents a significant problem in industrialized countries, with a high prevalence, morbidity, and mortality, where it is most frequently caused by coronary artery disease. Revascularization in patients with symptomatic heart failure has been associated with improved cardiovascular outcomes. Predictors o...

journal_title：Seminars in nuclear medicine

authors： Lim SP,Mc Ardle BA,Beanlands RS,Hessian RC

更新日期：2014-09-01 00:00:00

abstract：:The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s. Today, despite the many advances in imaging instrumentation, radiopharmaceuticals, and methodology over these years, cholescintigraphy still plays an important role in confirming or excl...

journal_title：Seminars in nuclear medicine

authors： Ziessman HA

更新日期：2003-10-01 00:00:00

abstract：:The radionuclide bone scan is one of the most commonly performed pediatric nuclear medicine procedures. Bone scintigraphy is used as the diagnostic procedure of choice for diagnosis of bone and soft-tissue infection and can aid in the diagnosis of occult trauma without radiographic findings. There is a complimentary r...

journal_title：Seminars in nuclear medicine

authors： Nadel HR

更新日期：2007-09-01 00:00:00

abstract：:Adrenal scintigraphy is a unique nuclear medicine procedure that provides noninvasive, functional information concerning the status of the adrenal cortex. The uptake of iodocholesterol, in addition to localizing adrenal cortical abnormalities, can be manipulate to focus on adrenal cortical dysfunction in either the al...

journal_title：Seminars in nuclear medicine

authors： Gross MD,Valk TW,Swanson DP,Thrall JH,Grekin RJ,Beirewaltes WH

更新日期：1981-04-01 00:00:00

abstract：:FDG is a tracer for visualizing glucose metabolism. PET/CT using FDG is widely used for the diagnosis of cancer, because glycolysis is elevated in cancer cells. Similarly, active inflammatory tissue also exhibits elevated glucose metabolism because of glycolysis in activated macrophages and proliferating fibroblasts. ...

journal_title：Seminars in nuclear medicine

authors： Kubota K,Yamashita H,Mimori A

更新日期：2017-07-01 00:00:00

abstract：:When serious infections are suspected, patients are often treated empirically with broad-spectrum antibiotics while awaiting results that provide information on the bacterial class and species causing the infection, as well as drug susceptibilities. For deep-seated infections, these traditional diagnostic techniques o...

journal_title：Seminars in nuclear medicine

authors： Ordonez AA,Jain SK

更新日期：2018-03-01 00:00:00

abstract：:Rhenium-186 (tin)hydroxyethylidene diphosphonate (HEDP) is a new radiopharmaceutical that localizes in skeletal metastases in patients with advanced cancer. A single intravenous administration of approximately 34 mCi (1,258 MBq) resulted in significant improvement in pain in 33 of 43 evaluable patients (77%) following...

journal_title：Seminars in nuclear medicine

authors： Maxon HR 3rd,Thomas SR,Hertzberg VS,Schroder LE,Englaro EE,Samaratunga R,Scher HI,Moulton JS,Deutsch EA,Deutsch KF

更新日期：1992-01-01 00:00:00

abstract：:In the past, T3 suppression testing was often required to confirm the presence of autonomous thyroid function in patients with borderline clinical and laboratory findings suggestive of hyperthyroidism or in euthyroid patients with the stigmata of Graves' disease. Similarly, TSH stimulation testing was used to document...

journal_title：Seminars in nuclear medicine

authors： Hurley JR,Becker DV

更新日期：1981-04-01 00:00:00

abstract：:Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...

journal_title：Seminars in nuclear medicine

authors： Hofman MS,Hicks RJ

更新日期：2016-09-01 00:00:00

abstract：:Most of the components of the thrombotic and fibrinolytic systems have at some time been evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have been promising enough to emerge from investigational status to routine clinical use. New approaches are being explored, including improv...

journal_title：Seminars in nuclear medicine

authors： Knight LC

更新日期：1990-01-01 00:00:00

abstract：:Recently, the lung has received increasing attention as a metabolic organ. In this role, the lung modulates the composition of the arterial blood by several mechanisms: removing active substances from the plasma, releasing substances into the plasma, temporarily holding substances from circulation, and activating or i...

journal_title：Seminars in nuclear medicine

authors： Touya JJ,Rahimian J,Corbus HF,Grubbs DE,Savala KM,Glass EC,Bennett LR

更新日期：1986-10-01 00:00:00

abstract：:A radionuclide procedure, hysterosalpingo-radionuclide scintigraphy (HERS), was designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries as well as to image and functionally outline the patency of the pathways between these two extremes of the female r...

journal_title：Seminars in nuclear medicine

authors： Iturralde M,Venter PF

更新日期：1981-10-01 00:00:00

abstract：:New software methods that incorporate iterative reconstruction, resolution recovery, and noise compensation now provide the ability to maintain or improve myocardial perfusion SPECT image quality with conventional sodium iodide cameras. Despite lower image counting statistics associated with significantly decreased in...

journal_title：Seminars in nuclear medicine

authors： Gordon DePuey E 3rd

更新日期：2014-07-01 00:00:00

abstract：:Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigr...

journal_title：Seminars in nuclear medicine

authors： Mandell GA,Alexander MA,Harcke HT

更新日期：1993-10-01 00:00:00