PET Assessment of Cardiac Allograft Vasculopathy.

abstract：:Prostate cancer (PCa) is one of the most common cancers in men and is the second leading cause of cancer-related deaths in the USA. In the United States, it is the second most frequently diagnosed cancer after skin cancer, and in Europe it is number one. According to the American Cancer Society, approximately 221,000 ...

journal_title：Seminars in nuclear medicine

authors： Evans-Axelsson S,Timmermand OV,Bjartell A,Strand SE,Elgqvist J

更新日期：2016-03-01 00:00:00

abstract：:Radionuclide angiocardiography and myocardial perfusion imaging with exercise are valuable methods to assess patients undergoing percutaneous transluminal coronary angioplasty. Successful angioplasty results in improvement in ventricular systolic and diastolic function and regional perfusion. Complications of angiopla...

journal_title：Seminars in nuclear medicine

authors： DePuey EG

更新日期：1991-04-01 00:00:00

abstract：:The objective of this work is to compare the characteristics of various techniques for functional renal imaging, with a focus on nuclear medicine and magnetic resonance imaging. Even with low spatial resolution and rather poor signal-to-noise ratio, classical nuclear medicine has the advantage of linearity and good se...

journal_title：Seminars in nuclear medicine

authors： Durand E,Chaumet-Riffaud P,Grenier N

更新日期：2011-01-01 00:00:00

abstract：:This review is directed at the clinically useful highlights of ultrasound and radionuclide testing in adults with coronary and valvular heart disease, intracardiac shunts, and hypertrophic and congestive cardiomyopathies. As a clinical toto, the radionuclide procedures are currently more useful than ultrasound examina...

journal_title：Seminars in nuclear medicine

authors： Horowitz SF,Goldsmith SJ,Meller J,Patterson RE,Teichholz LE

更新日期：1980-01-01 00:00:00

abstract：:Over the past several decades, PET has emerged as critical to accurate staging and restaging of lymphomas. Nonetheless, a number of critical issues regarding its optimal use remain. Whereas risk-adapted strategies appear to improve the outcome of patients with Hodgkin lymphoma, results are less convincing in non-Hodgk...

journal_title：Seminars in nuclear medicine

authors： Cheson BD

更新日期：2018-01-01 00:00:00

abstract：:The accumulation of radioactive tracer is associated with specific histological changes. Awareness of these changes permits a more specific interpretation of a positive bone scan, especially when correlating the radionuclide image with the plain radiographs. Increased uptake in the flow phase of an imaging study usual...

journal_title：Seminars in nuclear medicine

authors： McCarthy EF

更新日期：1997-10-01 00:00:00

abstract：:Autonomic innervation plays an important role in proper functioning of the cardiovascular system. Altered cardiac sympathetic function is present in a variety of diseases, and can be assessed with radionuclide imaging using sympathetic neurotransmitter analogues. The most studied adrenergic radiotracer is cardiac 123I...

journal_title：Seminars in nuclear medicine

authors： Wan N,Travin MI

更新日期：2020-07-01 00:00:00

abstract：:Long-awaited results from randomized clinical trials designed to test the validity of sentinel lymph node biopsy (SLNB) as replacement of axillary lymph node dissection (ALND) in management of early breast cancer have recently been published. All the trials conclude SLNB has survival rates comparable to those of ALND ...

journal_title：Seminars in nuclear medicine

authors： Moncayo VM,Aarsvold JN,Grant SF,Bartley SC,Alazraki NP

更新日期：2013-07-01 00:00:00

abstract：:Ventilation/Perfusion (V/Q) positron emission tomography computed tomography (PET/CT) is now possible by substituting Technetium-99m (99mTc) with Gallium-68 (68Ga), using the same carrier molecules as conventional V/Q imaging. Ventilation imaging can be performed with 68Ga-carbon nanoparticles using the same synthesis...

journal_title：Seminars in nuclear medicine

authors： Le Roux PY,Hicks RJ,Siva S,Hofman MS

更新日期：2019-01-01 00:00:00

abstract：:When serious infections are suspected, patients are often treated empirically with broad-spectrum antibiotics while awaiting results that provide information on the bacterial class and species causing the infection, as well as drug susceptibilities. For deep-seated infections, these traditional diagnostic techniques o...

journal_title：Seminars in nuclear medicine

authors： Ordonez AA,Jain SK

更新日期：2018-03-01 00:00:00

abstract：:The past several years have seen marked advances in technetium/rhenium chemistry applicable to the preparation of new 99mTc-labeled radiopharmaceuticals. This article focuses on recent developments in technetium chemistry, including the preparation of "3 + 1" complexes, the preparation and use of (99mTc[CO]3)+ complex...

journal_title：Seminars in nuclear medicine

authors： Mease RC,Lambert C

更新日期：2001-10-01 00:00:00

abstract：:The convenience of (18)F-fluoride imaging is undeniable both because of its favorable tracer and because of its technical characteristics, including high image quality and short examination times leading to increased patient comfort. Depending on the activity administered, the radiation dose to patients is about compa...

journal_title：Seminars in nuclear medicine

authors： Fischer DR

更新日期：2013-11-01 00:00:00

abstract：:Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigr...

journal_title：Seminars in nuclear medicine

authors： Mandell GA,Alexander MA,Harcke HT

更新日期：1993-10-01 00:00:00

abstract：:This review describes general concepts with regard to radiopharmaceuticals for diagnostic or therapeutic applications that help to understand the specific challenges encountered during the design, (radio)synthesis, in vitro and in vivo evaluation and clinical translation of novel radiopharmaceuticals. The design of a ...

journal_title：Seminars in nuclear medicine

authors： Vermeulen K,Vandamme M,Bormans G,Cleeren F

更新日期：2019-09-01 00:00:00

abstract：:Tc-99m pyrophosphate is the grandfather of infarct avid agents. Its value is its clinical availability and ease of use. However, its shortcomings are the delay of 2 to 3 days for reliable interpretation in nonreperfused myocardial infarction (MI) and the overarching bone activity. Antimyosin provides exquisite specifi...

journal_title：Seminars in nuclear medicine

authors： Khaw BA

更新日期：1999-07-01 00:00:00

abstract：:Radioimmunotherapy is a promising new therapeutic option for the treatment of B-cell non-Hodgkin's lymphoma. Several monoclonal antibody and radionuclide conjugates, including I-131 tositumomab and Y-90 ibritumomab, have been investigated in clinical trials. Yttrium 90 ibritumomab tiuxetan (Zevalin; Biogen Idec Inc, C...

journal_title：Seminars in nuclear medicine

authors： Zimmer AM

更新日期：2004-01-01 00:00:00

abstract：:Several antineuroblastoma monoclonal antibodies (MoAbs) have been described and two have been used in radioimmunoimaging and radioimmunotherapy in patients. MoAb 3F8 is a murine IgG3 antibody specific for the ganglioside GD2. Radioiodine-labeled 3F8 has been shown to specifically target human neuroblastoma in patients...

journal_title：Seminars in nuclear medicine

authors： Miraldi F

更新日期：1989-10-01 00:00:00

abstract：:There is little information in the literature concerning the role of bone scanning in benign bone neoplasms except for sporadic reports. Since the advent of 99mTc-polyphosphate, bone imaging has proven feasible and useful in locating the cause of bone pain, such as in osteoid osteomas, which are not always radiologica...

journal_title：Seminars in nuclear medicine

authors： Gilday DL,Ash JM

更新日期：1976-01-01 00:00:00

abstract：:Radiolabeling of red cells and their clinical and research application in nuclear medicine constitute an area of continued interest and steady growth during the past two decades. Significant advances have been made so that at the present time, radiolabels with sufficient in vitro and in vivo stability are available fo...

journal_title：Seminars in nuclear medicine

authors： Srivastava SC,Chervu LR

更新日期：1984-04-01 00:00:00

abstract：:In the 1980s, the (111)In-labeled somatostatin analog OctreoScan (Covidien, Hazelwood, MO) was developed for imaging of somatostatin receptor subtype 2 (sst(2)) overexpressing tumors. On the basis of this success, peptide receptor radionuclide therapy (PRRT) was developed using similar somatostatin analogs with differ...

journal_title：Seminars in nuclear medicine

authors： Pool SE,Krenning EP,Koning GA,van Eijck CH,Teunissen JJ,Kam B,Valkema R,Kwekkeboom DJ,de Jong M

更新日期：2010-05-01 00:00:00

abstract：:In the past 20 years there have been great advances in our understanding of the molecular genetics of gastrointestinal tumors. In general, cancers develop and proliferate due to: driver mutations or related alterations in the genome resulting in overactivity of oncogenes, underactivity of tumor suppressor genes allowi...

journal_title：Seminars in nuclear medicine

authors： Wahl RL

更新日期：2020-09-01 00:00:00

abstract：:Concern about the spread of infections in the hospital setting has prompted regulatory agencies to mandate infection control standards. Each hospital department is required to have written policies and procedures which describe measures to prevent and control the spread of nosocomial infections (hospital acquired infe...

journal_title：Seminars in nuclear medicine

authors： Adams A,Egan A

更新日期：1988-10-01 00:00:00

abstract：:More than 7 million stress perfusion studies are performed in the United States annually, 44% with pharmacological vasodilator stress agents. Both adenosine and dipyridamole are nonselective coronary vasodilators that are commonly used for stress perfusion imaging. These agents are safe and provide an effective means ...

journal_title：Seminars in nuclear medicine

authors： Druz RS

更新日期：2009-05-01 00:00:00

abstract：:Uneven distribution of ventilation, or ventilation heterogeneity, has been observed in asthma for over 60 years using multiple breath nitrogen washout (MBNW) studies. Ventilation heterogeneity has been known to predict airway hyperresponsiveness (the ability of the airways to constrict too easily and by too much) in a...

journal_title：Seminars in nuclear medicine

authors： Farrow C,King G

更新日期：2019-01-01 00:00:00

abstract：:Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are now more and more available for clinical use. PET/MR combines the unique features of MR including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as we...

journal_title：Seminars in nuclear medicine

authors： Sollini M,Berchiolli R,Kirienko M,Rossi A,Glaudemans AWJM,Slart R,Erba PA

更新日期：2018-05-01 00:00:00

abstract：:The concept of brain death has gained importance in the past few decades to prevent futile attempts to sustain ventilation and blood circulation when the brain has lost all function and to procure beneficial tissues or life-saving organs for transplantation. However, differences remain among professional societies and...

journal_title：Seminars in nuclear medicine

authors： Sinha P,Conrad GR

更新日期：2012-01-01 00:00:00

abstract：:The advent of simultaneous PET/MRI brought a large amount of possibilities in research and clinical applications into hybrid imaging. Unlike in PET/CT protocols, the MR component provides an almost unlimited number of pulse sequences and possibilities of different protocols in PET/MRI. Nevertheless, there is an impera...

journal_title：Seminars in nuclear medicine

authors： Barbosa Fde G,von Schulthess G,Veit-Haibach P

更新日期：2015-07-01 00:00:00

abstract：:Positron emission tomography (PET)/computed tomography (CT) is a rapidly expanding imaging modality, thanks to the availability of compact medical cyclotrons and automated chemistry synthesis modules for the production of PET radiopharmaceuticals. Despite the availability of many radiotracers, [(18)F]fluorodeoxyglucos...

journal_title：Seminars in nuclear medicine

authors： Vallabhajosula S,Solnes L,Vallabhajosula B

更新日期：2011-07-01 00:00:00

abstract：:Regional cerebral blood flow (rCBF) findings and their application to cerebrovascular disease are reviewed. Although the coupling of cerebral blood flow and metabolism are best studied with positron emission tomography, single-photon emission computed tomography measurements of rCBF can contribute to patient managemen...

journal_title：Seminars in nuclear medicine

authors： Hellman RS,Tikofsky RS

更新日期：1990-10-01 00:00:00

abstract：:In the past, T3 suppression testing was often required to confirm the presence of autonomous thyroid function in patients with borderline clinical and laboratory findings suggestive of hyperthyroidism or in euthyroid patients with the stigmata of Graves' disease. Similarly, TSH stimulation testing was used to document...

journal_title：Seminars in nuclear medicine

authors： Hurley JR,Becker DV

更新日期：1981-04-01 00:00:00