An overview of the contribution of regional cerebral blood flow studies in cerebrovascular disease: is there a role for single photon emission computed tomography?

abstract：:Nuclear dacryocystography is simple, relatively harmless method of evaluating patients suspected of having abnormalities of the nasolacrimal drainage system. A group of normal saline containing approximately 100 muCi of 99mTc-pertechnetate is placed on the conjunctiva near the lateral canthus, and serial scintigrams a...

journal_title：Seminars in nuclear medicine

authors： Brown M,El Gammal TA,Luxenberg MN,Eubig C

更新日期：1981-10-01 00:00:00

abstract：:The results of quantitative analysis of planar thallium-201 stress scintigraphy are superior to those of visual analysis. The increased sensitivity for detection of coronary artery disease is associated with maintenance of specificity. Consequently, we believe that quantitative analysis is the state-of-the-art for pla...

journal_title：Seminars in nuclear medicine

authors： Wackers FJ,Fetterman RC,Mattera JA,Clements JP

更新日期：1985-01-01 00:00:00

abstract：:The past several years have seen marked advances in technetium/rhenium chemistry applicable to the preparation of new 99mTc-labeled radiopharmaceuticals. This article focuses on recent developments in technetium chemistry, including the preparation of "3 + 1" complexes, the preparation and use of (99mTc[CO]3)+ complex...

journal_title：Seminars in nuclear medicine

authors： Mease RC,Lambert C

更新日期：2001-10-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:Up to 25% of the diabetic population is at risk for developing a pedal ulcer. These ulcers serve as a portal of entry for osteomyelitis and overlie more than 90% of diabetic pedal osteomyelitis cases. The diagnosis of osteomyelitis often is overlooked, and imaging studies are an essential part of the evaluation. The m...

journal_title：Seminars in nuclear medicine

authors： Palestro CJ,Love C

更新日期：2009-01-01 00:00:00

abstract：:Ventilation/Perfusion (V/Q) positron emission tomography computed tomography (PET/CT) is now possible by substituting Technetium-99m (99mTc) with Gallium-68 (68Ga), using the same carrier molecules as conventional V/Q imaging. Ventilation imaging can be performed with 68Ga-carbon nanoparticles using the same synthesis...

journal_title：Seminars in nuclear medicine

authors： Le Roux PY,Hicks RJ,Siva S,Hofman MS

更新日期：2019-01-01 00:00:00

abstract：:The use of gallium for pulmonary diseases is hampered by its relative lack of specificity, typical 1- to 3-day delay between injection and imaging time, and suboptimal imaging characteristics. Other nuclear and nonnuclear imaging modalities, such as (18)F-fluorodeoxyglucose positron emission tomography (PET) and high-...

journal_title：Seminars in nuclear medicine

authors： Schuster DM,Alazraki N

更新日期：2002-07-01 00:00:00

abstract：:Carcinoma of the lung is one of the most frequent malignancies and a major cause of mortality. The use of positron emission tomography (PET) has been extensively investigated in patients with carcinoma of the lung and has established clinical utility and cost-effectiveness in characterization of solitary pulmonary nod...

journal_title：Seminars in nuclear medicine

authors： Shon IH,O'doherty MJ,Maisey MN

更新日期：2002-10-01 00:00:00

abstract：:The high-level expression of somatostatin receptors (SSTR) on various tumor cells has provided the molecular basis for successful use of radiolabeled peptide analogues as tumor tracers in nuclear medicine. The vast majority of human tumors seem to overexpress one or the other of 5 distinct hSSTR subtype receptors. Whe...

journal_title：Seminars in nuclear medicine

authors： Virgolini I,Britton K,Buscombe J,Moncayo R,Paganelli G,Riva P

更新日期：2002-04-01 00:00:00

abstract：:Most of the components of the thrombotic and fibrinolytic systems have at some time been evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have been promising enough to emerge from investigational status to routine clinical use. New approaches are being explored, including improv...

journal_title：Seminars in nuclear medicine

authors： Knight LC

更新日期：1990-01-01 00:00:00

abstract：:FDG-PET/CT has an established role in the initial staging of locally advanced cervical cancers, particularly in evaluation of nodal disease and distant metastases. It is common practice to perform FDG-PET/CT 3 months postcompletion of chemoradiotherapy as it can predict outcome and be used to tailor management, includ...

journal_title：Seminars in nuclear medicine

authors： Gandy N,Arshad MA,Park WE,Rockall AG,Barwick TD

更新日期：2019-11-01 00:00:00

abstract：:Identification of patients with renovascular hypertension (RVH) among the larger group of patients with essential hypertension has been aided by a wide variety of in vitro and in vivo nuclear medicine procedures. The most valuable in vitro procedure remains the radioimmunoassay (RIA) for renin activity obtained from i...

journal_title：Seminars in nuclear medicine

authors： Fine EJ,Sarkar S

更新日期：1989-04-01 00:00:00

abstract：:Adrenal scintigraphy is a unique nuclear medicine procedure that provides noninvasive, functional information concerning the status of the adrenal cortex. The uptake of iodocholesterol, in addition to localizing adrenal cortical abnormalities, can be manipulate to focus on adrenal cortical dysfunction in either the al...

journal_title：Seminars in nuclear medicine

authors： Gross MD,Valk TW,Swanson DP,Thrall JH,Grekin RJ,Beirewaltes WH

更新日期：1981-04-01 00:00:00

abstract：:Nuclear medicine imaging techniques continue to play a unique role in the evaluation of hepatic masses. Although many useful radiodiagnostic agents are available, the predominant nuclear medicine study used to evaluate hepatic masses in this decade is technetium-labeled red blood cell "blood-pool" scintigraphy. Hepati...

journal_title：Seminars in nuclear medicine

authors： Middleton ML

更新日期：1996-01-01 00:00:00

abstract：:We describe our all-digital, filmless, department of nuclear medicine, which has been fully operational for 3 years. The approach to the design and implementation of a nuclear medicine picture archiving and communication system (PACS) is discussed, as well as enhancements found to be necessary or desirable during our ...

journal_title：Seminars in nuclear medicine

authors： Cohen AM,Parker JA,Donohoe K,Jansons D,Kolodny GM

更新日期：1990-07-01 00:00:00

abstract：:Malignant endocrine disorders have been an enigma over the last few decades, from genetic, clinical, and imaging perspectives. The detection of the primary tumor and the identification of recurrent disease have been essentially based on various anatomic techniques, with localization procedures extensively developed fo...

journal_title：Seminars in nuclear medicine

authors： Krausz Y

更新日期：2001-07-01 00:00:00

abstract：:The use of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in prostate cancer depends on the phase of the disease along the natural history of this prevalent malignancy in men. Incidental high FDG uptake in the prostate gland, although rare, should prompt further investigation with at least a meas...

journal_title：Seminars in nuclear medicine

authors： Jadvar H

更新日期：2016-11-01 00:00:00

abstract：:The advent of simultaneous PET/MRI brought a large amount of possibilities in research and clinical applications into hybrid imaging. Unlike in PET/CT protocols, the MR component provides an almost unlimited number of pulse sequences and possibilities of different protocols in PET/MRI. Nevertheless, there is an impera...

journal_title：Seminars in nuclear medicine

authors： Barbosa Fde G,von Schulthess G,Veit-Haibach P

更新日期：2015-07-01 00:00:00

abstract：:Image registration is finding increased clinical use both in aiding diagnosis and guiding therapy. There are numerous algorithms for registration, which all involve maximizing a measure of similarity between a transformed floating image and a fixed reference image. The choice of the similarity measure depends, to some...

journal_title：Seminars in nuclear medicine

authors： Hutton BF,Braun M

更新日期：2003-07-01 00:00:00

abstract：:The basic principles of the use of radiation dosimetry in nuclear medicine are reviewed. The basic structure of the main mathematical equations are given and formal dosimetry systems are discussed. An extensive overview of the history and current status of anthropomorphic models (phantoms) is given. The sources and ma...

journal_title：Seminars in nuclear medicine

authors： Stabin M,Xu XG

更新日期：2014-05-01 00:00:00

abstract：:The definition of tumor involved volumes in patients with head and neck cancer poses great challenges with the increasing use of highly conformal radiotherapy techniques eg, volumetric modulated arc therapy and intensity modulated proton therapy. The risk of underdosing the tumor might increase unless great care is ta...

journal_title：Seminars in nuclear medicine

authors： Jensen K,Al-Farra G,Dejanovic D,Eriksen JG,Loft A,Hansen CR,Pameijer FA,Zukauskaite R,Grau C

更新日期：2021-01-01 00:00:00

abstract：:The process of discovering and developing a new pharmaceutical is a long, difficult, and risky process that requires numerous resources. Molecular imaging techniques such as PET have recently become a useful tool for making decisions along a drug candidate's development timeline. PET is a translational, noninvasive im...

journal_title：Seminars in nuclear medicine

authors： Donnelly DJ

更新日期：2017-09-01 00:00:00

abstract：:The advantage of immunoscintigraphy over autologous leukocyte techniques in the imaging of infection is the simplicity of its use compared with techniques that require the isolation of autologous white blood cells. The advantage over 99mTc- or 111In-labeled nonspecific human immunoglobulin is the excellent target-to-b...

journal_title：Seminars in nuclear medicine

authors： Becker W,Goldenberg DM,Wolf F

更新日期：1994-04-01 00:00:00

abstract：:The increasing use of automated blood chemistry screens for serum calcium levels along with improved methods in measuring parathyroid hormone (PTH) levels have made the diagnosis of parathyroid disease a common clinical problem. Parathyroid adenomas account for the majority of primary hyperparathyroidism with diffuse ...

journal_title：Seminars in nuclear medicine

authors： Winzelberg GG,Hydovitz JD

更新日期：1985-04-01 00:00:00

abstract：:Neurochemical imaging is one of the most established "molecular" imaging techniques. There have been tremendous efforts expended to develop radioligands specific to each neurochemical system. Investigational applications of neurochemical imaging in dementing disorders are extensive. Cholinergic, dopaminergic, and sero...

journal_title：Seminars in nuclear medicine

authors： Minoshima S,Frey KA,Cross DJ,Kuhl DE

更新日期：2004-01-01 00:00:00

abstract：:Detection of acute myocardial infarction as an area of increased activity has intrigued investigators for some time. Initial attempts with 203Hg-chlormerodrin and 203Hg-fluorescein analogues were successful in man. More recently, however, successful imaging of the acute myocardial infarct has been achieved with severa...

journal_title：Seminars in nuclear medicine

authors： Holman BL,Davis MA,Hanson RN

更新日期：1977-01-01 00:00:00

abstract：:This review is directed at the clinically useful highlights of ultrasound and radionuclide testing in adults with coronary and valvular heart disease, intracardiac shunts, and hypertrophic and congestive cardiomyopathies. As a clinical toto, the radionuclide procedures are currently more useful than ultrasound examina...

journal_title：Seminars in nuclear medicine

authors： Horowitz SF,Goldsmith SJ,Meller J,Patterson RE,Teichholz LE

更新日期：1980-01-01 00:00:00

abstract：:The accumulation of radioactive tracer is associated with specific histological changes. Awareness of these changes permits a more specific interpretation of a positive bone scan, especially when correlating the radionuclide image with the plain radiographs. Increased uptake in the flow phase of an imaging study usual...

journal_title：Seminars in nuclear medicine

authors： McCarthy EF

更新日期：1997-10-01 00:00:00

abstract：:Prostate cancer remains an important and growing health problem. Advances in imaging of prostate cancer may help to achieve earlier and more accurate diagnosis and treatment. We review the various strategies using reporter genes for molecular imaging of prostate cancer. These approaches are emerging as valuable tools ...

journal_title：Seminars in nuclear medicine

authors： Singh A,Massoud TF,Deroose C,Gambhir SS

更新日期：2008-01-01 00:00:00

abstract：:The role of labeled tracers in radioimmunoassay procedures (RIA) and the advantages of the iodine-labeled antigens over 14C or tritium-labeled antigens are discussed. Different methods of labeling with iodine isotopes are presented. The ease with which microgram amounts of hormonal proteins are tagged, achieving high...

journal_title：Seminars in nuclear medicine

authors： Chervu LR,Murty DR

更新日期：1975-04-01 00:00:00