Histopathologic correlates of a positive bone scan.

abstract：:Graft infection following prosthetic vascular reconstruction is an uncommon but severe complication. The clinical presentation is often subtle and nonspecific and may occur long after surgery. Although defining a prosthetic vascular graft infection can be difficult, early diagnosis and treatment are essential for the ...

journal_title：Seminars in nuclear medicine

authors： Keidar Z,Nitecki S

更新日期：2013-09-01 00:00:00

abstract：:The high-level expression of somatostatin receptors (SSTR) on various tumor cells has provided the molecular basis for successful use of radiolabeled peptide analogues as tumor tracers in nuclear medicine. The vast majority of human tumors seem to overexpress one or the other of 5 distinct hSSTR subtype receptors. Whe...

journal_title：Seminars in nuclear medicine

authors： Virgolini I,Britton K,Buscombe J,Moncayo R,Paganelli G,Riva P

更新日期：2002-04-01 00:00:00

abstract：:FDG is a tracer for visualizing glucose metabolism. PET/CT using FDG is widely used for the diagnosis of cancer, because glycolysis is elevated in cancer cells. Similarly, active inflammatory tissue also exhibits elevated glucose metabolism because of glycolysis in activated macrophages and proliferating fibroblasts. ...

journal_title：Seminars in nuclear medicine

authors： Kubota K,Yamashita H,Mimori A

更新日期：2017-07-01 00:00:00

abstract：:Computer processing can improve the quality of scintigrams in several ways. It can increase the accuracy with which the image approximates the activity distribution by reversing degradation. It can selectively enhance normal or abnormal structures of interest. It can optimize the use of the display system presenting t...

journal_title：Seminars in nuclear medicine

authors： Pizer SM,Todd-Pokropek AE

更新日期：1978-04-01 00:00:00

abstract：:Vital blue dyes were used to show the feasibility and accuracy of intraoperative lymphatic mapping of the sentinel node (SN) in patients with melanoma, breast cancer, and other solid tumors. Surgeons who have successfully completed an adequate number of cases of intraoperative mapping and sentinel lymph node dissectio...

journal_title：Seminars in nuclear medicine

authors： Bostick PJ,Giuliano AE

更新日期：2000-01-01 00:00:00

abstract：:The results of quantitative analysis of planar thallium-201 stress scintigraphy are superior to those of visual analysis. The increased sensitivity for detection of coronary artery disease is associated with maintenance of specificity. Consequently, we believe that quantitative analysis is the state-of-the-art for pla...

journal_title：Seminars in nuclear medicine

authors： Wackers FJ,Fetterman RC,Mattera JA,Clements JP

更新日期：1985-01-01 00:00:00

abstract：:The diphosphonate bone scan is ideally suited to assess many global, focal or multifocal metabolic bone disorders and there remains a role for conventional bone scintigraphy in metabolic bone disorders at diagnosis, investigation of complications, and treatment response assessment. In contrast, the role of bone scinti...

journal_title：Seminars in nuclear medicine

authors： Cook GJ,Gnanasegaran G,Chua S

更新日期：2010-01-01 00:00:00

abstract：:The role of labeled tracers in radioimmunoassay procedures (RIA) and the advantages of the iodine-labeled antigens over 14C or tritium-labeled antigens are discussed. Different methods of labeling with iodine isotopes are presented. The ease with which microgram amounts of hormonal proteins are tagged, achieving high...

journal_title：Seminars in nuclear medicine

authors： Chervu LR,Murty DR

更新日期：1975-04-01 00:00:00

abstract：:At the present time, there are three radiolabeled antibodies that have been approved by the US Food and Drug Administration (FDA) for imaging of cancer, a fourth commercially sponsored product recommended for approval (as of 10/29/96, cap romab pendetide (ProstaScint; Cytogen Corp., Princeton, NJ) was upgraded from re...

journal_title：Seminars in nuclear medicine

authors： Zuckier LS,DeNardo GL

更新日期：1997-01-01 00:00:00

abstract：:Computer tomography (CT) is a radiological imaging method which yields transverse tomographic images reflecting with high accuracy the spatial distribution of x-ray attenuation in the part examined. The contrast resolution achieved by CT permits the visualization of soft tissue structure heretofore invisible with conv...

journal_title：Seminars in nuclear medicine

authors： Ter-Pogossian MM

更新日期：1977-04-01 00:00:00

abstract：:While 99mTc sulfur colloid imaging, because of its availability and convenience, remains the initial procedure of choice for spleen imaging, selective spleen scanning with damaged 99mTc-labeled RBCs can provide additional information in some cases. These cases include overlapping left hepatic lobe and suspected spleni...

journal_title：Seminars in nuclear medicine

authors： Armas RR

更新日期：1985-07-01 00:00:00

abstract：:Blood cell labeling with 99mTc has progressed through various developmental phases. In the case of red cell labeling, the science seems to have matured sufficiently, although minor refinements in the procedures will no doubt continue to be made. During the last 3 to 5 years, there has been a resurgence of interest in ...

journal_title：Seminars in nuclear medicine

authors： Srivastava SC,Straub RF

更新日期：1990-01-01 00:00:00

abstract：:This review, examines the indications for and limitations of gallium-67 (67Ga) scanning in the evaluation of patients infected with human immunodeficiency virus (HIV). The imaging protocol, as well as the normal biodistribution of 67Ga and its normal variants are discussed. The diagnostic significance of the different...

journal_title：Seminars in nuclear medicine

authors： Bekerman C,Bitran J

更新日期：1988-10-01 00:00:00

abstract：:In epilepsy, a detailed history, blood chemistry, routine electroencephalography, and brain MRI are important for the diagnosis of seizure type or epilepsy syndrome for the decision of appropriate drug treatment. Although antiepileptic drugs are mostly successful for controlling epileptic seizures, 20%-30% patients ar...

journal_title：Seminars in nuclear medicine

authors： Ergün EL,Saygi S,Yalnizoglu D,Oguz KK,Erbas B

更新日期：2016-07-01 00:00:00

abstract：:Molecular imaging has revolutionized clinical oncology by imaging-specific facets of cancer biology. Through noninvasive measurements of tumor physiology, targeted radiotracers can serve as biomarkers for disease characterization, prognosis, response assessment, and predicting long-term response/survival. In turn, the...

journal_title：Seminars in nuclear medicine

authors： Gillman JA,Pantel AR,Mankoff DA,Edmonds CE

更新日期：2020-11-01 00:00:00

abstract：:Positron emission tomography (PET) makes it possible for the first time to examine in living humans the chemistry of the brain, which relates the structures of the brain to the functions of the mind. PET scans make it possible to assess the state of neurotransmitter receptors, such as the dopamine, serotonin, muscarin...

journal_title：Seminars in nuclear medicine

authors： Wagner HN Jr

更新日期：1986-01-01 00:00:00

abstract：:A radionuclide procedure, hysterosalpingo-radionuclide scintigraphy (HERS), was designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries as well as to image and functionally outline the patency of the pathways between these two extremes of the female r...

journal_title：Seminars in nuclear medicine

authors： Iturralde M,Venter PF

更新日期：1981-10-01 00:00:00

abstract：:Suspecting and diagnosing venous thrombosis and pulmonary embolism remain major clinical problems. For a variety of reasons, including the patient's pre-existing cardiac and pulmonary status and the release of humoral mediators, pulmonary emboli evoke varied responses in different patients. Symptoms and signs of pulmo...

journal_title：Seminars in nuclear medicine

authors： Palevsky HI

更新日期：1991-10-01 00:00:00

abstract：:Regional cerebral blood flow (rCBF) findings and their application to cerebrovascular disease are reviewed. Although the coupling of cerebral blood flow and metabolism are best studied with positron emission tomography, single-photon emission computed tomography measurements of rCBF can contribute to patient managemen...

journal_title：Seminars in nuclear medicine

authors： Hellman RS,Tikofsky RS

更新日期：1990-10-01 00:00:00

abstract：:Ventilation/Perfusion (V/Q) positron emission tomography computed tomography (PET/CT) is now possible by substituting Technetium-99m (99mTc) with Gallium-68 (68Ga), using the same carrier molecules as conventional V/Q imaging. Ventilation imaging can be performed with 68Ga-carbon nanoparticles using the same synthesis...

journal_title：Seminars in nuclear medicine

authors： Le Roux PY,Hicks RJ,Siva S,Hofman MS

更新日期：2019-01-01 00:00:00

abstract：:Compared with planar imaging, ventilation/perfusion scintigraphy performed with single-photon emission computed tomography (SPECT) has a greater sensitivity and specificity, greater accuracy, improved reproducibility, and a lower number of inconclusive reports in the detection of pulmonary embolism. Despite these impr...

journal_title：Seminars in nuclear medicine

authors： Roach PJ,Bailey DL,Schembri GP,Thomas PA

更新日期：2010-11-01 00:00:00

abstract：:Several antineuroblastoma monoclonal antibodies (MoAbs) have been described and two have been used in radioimmunoimaging and radioimmunotherapy in patients. MoAb 3F8 is a murine IgG3 antibody specific for the ganglioside GD2. Radioiodine-labeled 3F8 has been shown to specifically target human neuroblastoma in patients...

journal_title：Seminars in nuclear medicine

authors： Miraldi F

更新日期：1989-10-01 00:00:00

abstract：:Prostate cancer remains an important and growing health problem. Advances in imaging of prostate cancer may help to achieve earlier and more accurate diagnosis and treatment. We review the various strategies using reporter genes for molecular imaging of prostate cancer. These approaches are emerging as valuable tools ...

journal_title：Seminars in nuclear medicine

authors： Singh A,Massoud TF,Deroose C,Gambhir SS

更新日期：2008-01-01 00:00:00

abstract：:This review summarizes the role of SPECT/CT in patients with a painful postoperative knee and describes typical diagnostic criteria in these patients. Pain after knee surgery is common and is influenced by the underlying pathology, the type of surgery, and the patient. Knee joint-preserving surgery includes osteotomy,...

journal_title：Seminars in nuclear medicine

authors： van der Bruggen W,Hirschmann MT,Strobel K,Kampen WU,Kuwert T,Gnanasegaran G,Van den Wyngaert T,Paycha F

更新日期：2018-09-01 00:00:00

abstract：:The radionuclide bone scan is one of the most commonly performed pediatric nuclear medicine procedures. Bone scintigraphy is used as the diagnostic procedure of choice for diagnosis of bone and soft-tissue infection and can aid in the diagnosis of occult trauma without radiographic findings. There is a complimentary r...

journal_title：Seminars in nuclear medicine

authors： Nadel HR

更新日期：2007-09-01 00:00:00

abstract：:Radiolabeling of red cells and their clinical and research application in nuclear medicine constitute an area of continued interest and steady growth during the past two decades. Significant advances have been made so that at the present time, radiolabels with sufficient in vitro and in vivo stability are available fo...

journal_title：Seminars in nuclear medicine

authors： Srivastava SC,Chervu LR

更新日期：1984-04-01 00:00:00

abstract：:The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s. Today, despite the many advances in imaging instrumentation, radiopharmaceuticals, and methodology over these years, cholescintigraphy still plays an important role in confirming or excl...

journal_title：Seminars in nuclear medicine

authors： Ziessman HA

更新日期：2003-10-01 00:00:00

abstract：:According to SEER Cancer Statistics Review there are around 165,000 new prostate cancer cases estimated in 2018 accounting for 9.5% of all newly diagnosed cancers. Accurate staging of primary prostate cancer is important for therapy selection (local vs systemic). Recent developments in molecular imaging may significan...

journal_title：Seminars in nuclear medicine

authors： Pomykala KL,Farolfi A,Hadaschik B,Fendler WP,Herrmann K

更新日期：2019-07-01 00:00:00

abstract：:This review describes general concepts with regard to radiopharmaceuticals for diagnostic or therapeutic applications that help to understand the specific challenges encountered during the design, (radio)synthesis, in vitro and in vivo evaluation and clinical translation of novel radiopharmaceuticals. The design of a ...

journal_title：Seminars in nuclear medicine

authors： Vermeulen K,Vandamme M,Bormans G,Cleeren F

更新日期：2019-09-01 00:00:00

abstract：:Recent advances in the efficient production of high purity radioiodine (123I) and new efficient radiolabeling techniques have allowed the development of new classes of cardiovascular radiopharmaceuticals. These include 123I-labeled fatty acids to assess myocardial metabolism, 123I-metaiodobenzylguanidine (MIBG) for my...

journal_title：Seminars in nuclear medicine

authors： Kulkarni PV,Corbett JR

更新日期：1990-04-01 00:00:00