The problems of the clinical and laboratory diagnosis of pulmonary embolism.

abstract：:The practice of nuclear medicine in children is well established for imaging practically all physiologic systems but particularly in the fields of oncology, neurology, urology, and orthopedics. Pediatric nuclear medicine yields images of physiologic and molecular processes that can provide essential diagnostic informa...

journal_title：Seminars in nuclear medicine

authors： Fahey FH,Goodkind AB,Plyku D,Khamwan K,O'Reilly SE,Cao X,Frey EC,Li Y,Bolch WE,Sgouros G,Treves ST

更新日期：2017-03-01 00:00:00

abstract：:Nuclear medicine imaging techniques continue to play a unique role in the evaluation of hepatic masses. Although many useful radiodiagnostic agents are available, the predominant nuclear medicine study used to evaluate hepatic masses in this decade is technetium-labeled red blood cell "blood-pool" scintigraphy. Hepati...

journal_title：Seminars in nuclear medicine

authors： Middleton ML

更新日期：1996-01-01 00:00:00

abstract：:In spite of localization of gallium in the lungs in a large variety of inflammatory pulmonary diseases, the chest radiograph is and will continue to be the principal diagnostic tool for evaluation of pulmonary inflammatory disease. The 67Ga-citrate scan, however, serves as a study complementary to chest radiography be...

journal_title：Seminars in nuclear medicine

authors： Bekerman C,Hoffer PB,Bitran JD,Gupta RG

更新日期：1980-07-01 00:00:00

abstract：:The use of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in prostate cancer depends on the phase of the disease along the natural history of this prevalent malignancy in men. Incidental high FDG uptake in the prostate gland, although rare, should prompt further investigation with at least a meas...

journal_title：Seminars in nuclear medicine

authors： Jadvar H

更新日期：2016-11-01 00:00:00

abstract：:99mTc-PYP myocardial scintigrams represent a means to detect and localize acute myocardial necrosis. These scintigrams are expected to be abnormal with acute myocardial infarcts of at least 3 grams in weight if serial imaging is utilized and proper attention to technique is provided. Any etiology of myocardial necrosi...

journal_title：Seminars in nuclear medicine

authors： Willerson JT,Parkey RW,Bonte FJ,Lewis SE,Corbett J,Buja LM

更新日期：1980-01-01 00:00:00

abstract：:Patients with previously treated thyroid carcinoma require lifelong monitoring for recurrent disease. Two diagnostic tests that play a central role in follow-up of these patients--radioiodine whole body scanning and serum thyroglobulin measurement--are most accurate during thyroid-stimulating hormone (TSH) stimulation...

journal_title：Seminars in nuclear medicine

authors： Ladenson PW

更新日期：2000-04-01 00:00:00

abstract：:The objective of this work is to compare the characteristics of various techniques for functional renal imaging, with a focus on nuclear medicine and magnetic resonance imaging. Even with low spatial resolution and rather poor signal-to-noise ratio, classical nuclear medicine has the advantage of linearity and good se...

journal_title：Seminars in nuclear medicine

authors： Durand E,Chaumet-Riffaud P,Grenier N

更新日期：2011-01-01 00:00:00

abstract：:The remarkable progress in immunologic techniques in the development of monoclonal antibodies offers the potential for powerful new tools for the detection of cardiovascular disorders, such as acute myocardial necrosis and acute deep venous thrombosis, in an accurate, safe, and noninvasive manner. Historically the use...

journal_title：Seminars in nuclear medicine

authors： Manspeaker P,Weisman HF,Schaible TF

更新日期：1993-04-01 00:00:00

abstract：:Breast cancer is the most common cause of bone metastases in women. Imaging studies are useful to identify bone involvement and associated complications, for follow-up of disease spread and for the assessment of response to therapy. Bone scintigraphy with (99m)technetium-labeled diphosphonates is most widely used, due...

journal_title：Seminars in nuclear medicine

authors： Ben-Haim S,Israel O

更新日期：2009-11-01 00:00:00

abstract：:In the past, T3 suppression testing was often required to confirm the presence of autonomous thyroid function in patients with borderline clinical and laboratory findings suggestive of hyperthyroidism or in euthyroid patients with the stigmata of Graves' disease. Similarly, TSH stimulation testing was used to document...

journal_title：Seminars in nuclear medicine

authors： Hurley JR,Becker DV

更新日期：1981-04-01 00:00:00

abstract：:The advantage of immunoscintigraphy over autologous leukocyte techniques in the imaging of infection is the simplicity of its use compared with techniques that require the isolation of autologous white blood cells. The advantage over 99mTc- or 111In-labeled nonspecific human immunoglobulin is the excellent target-to-b...

journal_title：Seminars in nuclear medicine

authors： Becker W,Goldenberg DM,Wolf F

更新日期：1994-04-01 00:00:00

abstract：:Radionuclide angiocardiography and myocardial perfusion imaging with exercise are valuable methods to assess patients undergoing percutaneous transluminal coronary angioplasty. Successful angioplasty results in improvement in ventricular systolic and diastolic function and regional perfusion. Complications of angiopla...

journal_title：Seminars in nuclear medicine

authors： DePuey EG

更新日期：1991-04-01 00:00:00

abstract：:The process of discovering and developing a new pharmaceutical is a long, difficult, and risky process that requires numerous resources. Molecular imaging techniques such as PET have recently become a useful tool for making decisions along a drug candidate's development timeline. PET is a translational, noninvasive im...

journal_title：Seminars in nuclear medicine

authors： Donnelly DJ

更新日期：2017-09-01 00:00:00

abstract：:A comprehensive review of the effects of exposure to low levels of ionizing radiation, BEIR VII-Phase 2: Health Risks From Exposure to Low Levels of Ionizing Radiation, was published in 2006. The BEIR (Biological Effects of Ionizing Radiation) reports are a series of publications by the National Academy of Sciences. T...

journal_title：Seminars in nuclear medicine

authors： Royal HD

更新日期：2008-09-01 00:00:00

abstract：:Up to 25% of the diabetic population is at risk for developing a pedal ulcer. These ulcers serve as a portal of entry for osteomyelitis and overlie more than 90% of diabetic pedal osteomyelitis cases. The diagnosis of osteomyelitis often is overlooked, and imaging studies are an essential part of the evaluation. The m...

journal_title：Seminars in nuclear medicine

authors： Palestro CJ,Love C

更新日期：2009-01-01 00:00:00

abstract：:Image registration is finding increased clinical use both in aiding diagnosis and guiding therapy. There are numerous algorithms for registration, which all involve maximizing a measure of similarity between a transformed floating image and a fixed reference image. The choice of the similarity measure depends, to some...

journal_title：Seminars in nuclear medicine

authors： Hutton BF,Braun M

更新日期：2003-07-01 00:00:00

abstract：:Neurochemical imaging is one of the most established "molecular" imaging techniques. There have been tremendous efforts expended to develop radioligands specific to each neurochemical system. Investigational applications of neurochemical imaging in dementing disorders are extensive. Cholinergic, dopaminergic, and sero...

journal_title：Seminars in nuclear medicine

authors： Minoshima S,Frey KA,Cross DJ,Kuhl DE

更新日期：2004-01-01 00:00:00

abstract：:Prostate cancer (PCa) is one of the most common cancers in men and is the second leading cause of cancer-related deaths in the USA. In the United States, it is the second most frequently diagnosed cancer after skin cancer, and in Europe it is number one. According to the American Cancer Society, approximately 221,000 ...

journal_title：Seminars in nuclear medicine

authors： Evans-Axelsson S,Timmermand OV,Bjartell A,Strand SE,Elgqvist J

更新日期：2016-03-01 00:00:00

abstract：:Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...

journal_title：Seminars in nuclear medicine

authors： Hofman MS,Hicks RJ

更新日期：2016-09-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:Molecular imaging has revolutionized clinical oncology by imaging-specific facets of cancer biology. Through noninvasive measurements of tumor physiology, targeted radiotracers can serve as biomarkers for disease characterization, prognosis, response assessment, and predicting long-term response/survival. In turn, the...

journal_title：Seminars in nuclear medicine

authors： Gillman JA,Pantel AR,Mankoff DA,Edmonds CE

更新日期：2020-11-01 00:00:00

abstract：:Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are now more and more available for clinical use. PET/MR combines the unique features of MR including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as we...

journal_title：Seminars in nuclear medicine

authors： Sollini M,Berchiolli R,Kirienko M,Rossi A,Glaudemans AWJM,Slart R,Erba PA

更新日期：2018-05-01 00:00:00

abstract：:Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigr...

journal_title：Seminars in nuclear medicine

authors： Mandell GA,Alexander MA,Harcke HT

更新日期：1993-10-01 00:00:00

abstract：:Recent advances in the efficient production of high purity radioiodine (123I) and new efficient radiolabeling techniques have allowed the development of new classes of cardiovascular radiopharmaceuticals. These include 123I-labeled fatty acids to assess myocardial metabolism, 123I-metaiodobenzylguanidine (MIBG) for my...

journal_title：Seminars in nuclear medicine

authors： Kulkarni PV,Corbett JR

更新日期：1990-04-01 00:00:00

abstract：:Positron emission tomography (PET)/computed tomography (CT) is a rapidly expanding imaging modality, thanks to the availability of compact medical cyclotrons and automated chemistry synthesis modules for the production of PET radiopharmaceuticals. Despite the availability of many radiotracers, [(18)F]fluorodeoxyglucos...

journal_title：Seminars in nuclear medicine

authors： Vallabhajosula S,Solnes L,Vallabhajosula B

更新日期：2011-07-01 00:00:00

abstract：:Myocardial perfusion imaging with 15O-water positron emission tomography (PET) is a validated tool for quantitative measurement of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Current scanner and software technology enable quantification of global and regional MBF in clinical PET myocardial perfusion...

journal_title：Seminars in nuclear medicine

authors： Maaniitty T,Knuuti J,Saraste A

更新日期：2020-05-01 00:00:00

abstract：:Blood cell labeling with 99mTc has progressed through various developmental phases. In the case of red cell labeling, the science seems to have matured sufficiently, although minor refinements in the procedures will no doubt continue to be made. During the last 3 to 5 years, there has been a resurgence of interest in ...

journal_title：Seminars in nuclear medicine

authors： Srivastava SC,Straub RF

更新日期：1990-01-01 00:00:00

abstract：:In epilepsy, a detailed history, blood chemistry, routine electroencephalography, and brain MRI are important for the diagnosis of seizure type or epilepsy syndrome for the decision of appropriate drug treatment. Although antiepileptic drugs are mostly successful for controlling epileptic seizures, 20%-30% patients ar...

journal_title：Seminars in nuclear medicine

authors： Ergün EL,Saygi S,Yalnizoglu D,Oguz KK,Erbas B

更新日期：2016-07-01 00:00:00

abstract：:This review, examines the indications for and limitations of gallium-67 (67Ga) scanning in the evaluation of patients infected with human immunodeficiency virus (HIV). The imaging protocol, as well as the normal biodistribution of 67Ga and its normal variants are discussed. The diagnostic significance of the different...

journal_title：Seminars in nuclear medicine

authors： Bekerman C,Bitran J

更新日期：1988-10-01 00:00:00

abstract：:Positron emission tomography (PET) using the radiotracer 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) can image cellular proliferation in human cancers in vivo. FLT uptake has been shown to correlate with pathology-based proliferation measurements, including the Ki-67 score, in a variety of human cancers. Unlike pathology...

journal_title：Seminars in nuclear medicine

authors： Salskov A,Tammisetti VS,Grierson J,Vesselle H

更新日期：2007-11-01 00:00:00