FLT: measuring tumor cell proliferation in vivo with positron emission tomography and 3'-deoxy-3'-[18F]fluorothymidine.

abstract：:Identification of patients with renovascular hypertension (RVH) among the larger group of patients with essential hypertension has been aided by a wide variety of in vitro and in vivo nuclear medicine procedures. The most valuable in vitro procedure remains the radioimmunoassay (RIA) for renin activity obtained from i...

journal_title：Seminars in nuclear medicine

authors： Fine EJ,Sarkar S

更新日期：1989-04-01 00:00:00

abstract：:One of the major mechanisms of implementing the International Atomic Energy Agency's (IAEA) programs in nuclear medicine has been through coordinated research projects (CRPs). In recent years, the IAEA has initiated a new type of CRP, called Doctoral CRP, in an attempt to further improve the effectiveness of its progr...

journal_title：Seminars in nuclear medicine

authors： Padhy AK,Dondi M

更新日期：2008-03-01 00:00:00

abstract：:Although electronic imaging was performed in the early 1950s in nuclear medicine, it was the introduction of computed tomography in 1972 that caused a revolution in medical imaging in that it marked the beginning of the inevitable transformation to digital imaging. This transformation is now more or less complete. Whi...

journal_title：Seminars in nuclear medicine

authors： Yaffe MJ

更新日期：2019-03-01 00:00:00

abstract：:Molecular medicine enhances the clinician's ability to accurately diagnose and treat disease, and many technological advances in diverse fields have made the translation of molecular medicine to the clinic possible. Nuclear medicine encompasses 2 technologies--single-photon emission computed tomography (SPECT) and pos...

journal_title：Seminars in nuclear medicine

authors： Rowland DJ,Cherry SR

更新日期：2008-05-01 00:00:00

abstract：:(18)F-fluorodeoxyglucose (FDG) is the radiotracer used in the vast majority of positron emission tomography (PET) cancer studies. FDG is a powerful radiotracer that provides valuable data in many cancer types. Normal FDG biodistribution is easily identified. In the PET-only era, physiological uptake provided important...

journal_title：Seminars in nuclear medicine

authors： Cohade C

更新日期：2010-07-01 00:00:00

abstract：:The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s. Today, despite the many advances in imaging instrumentation, radiopharmaceuticals, and methodology over these years, cholescintigraphy still plays an important role in confirming or excl...

journal_title：Seminars in nuclear medicine

authors： Ziessman HA

更新日期：2003-10-01 00:00:00

abstract：:The process of discovering and developing a new pharmaceutical is a long, difficult, and risky process that requires numerous resources. Molecular imaging techniques such as PET have recently become a useful tool for making decisions along a drug candidate's development timeline. PET is a translational, noninvasive im...

journal_title：Seminars in nuclear medicine

authors： Donnelly DJ

更新日期：2017-09-01 00:00:00

abstract：:Malignant endocrine disorders have been an enigma over the last few decades, from genetic, clinical, and imaging perspectives. The detection of the primary tumor and the identification of recurrent disease have been essentially based on various anatomic techniques, with localization procedures extensively developed fo...

journal_title：Seminars in nuclear medicine

authors： Krausz Y

更新日期：2001-07-01 00:00:00

abstract：:Sickling of erythrocytes in patients with S-hemoglobin causes marrow and bone infarction. The former can be demonstrated as a lack of 99mTc-sulfur colloid uptake on marrow imaging examination. These defects may resolve or persist long after the acute episode. If the bone is involved in the acute episode, imaging withi...

journal_title：Seminars in nuclear medicine

authors： Lutzker LG,Alavi A

更新日期：1976-01-01 00:00:00

abstract：:Postsurgical bile leaks can be associated with significant morbidity and even mortality, if not identified and treated at an early phase. Hepatobiliary iminodiacetic acid (HIDA) scan is an important test for detection of bile leaks in the postoperative abdomen. However, the lack of anatomical details on planar images ...

journal_title：Seminars in nuclear medicine

authors： Matesan M,Bermo M,Cruite I,Shih CH,Elojeimy S,Behnia F,Lewis D,Vesselle H

更新日期：2017-11-01 00:00:00

abstract：:Radionuclide renal studies are particularly well suited to pediatrics as renal problems in children usually are part of a dynamic process which requires serial assessment. The absence of side-effects and the low radiation dose has added to their popularity in pediatrics. A number of different renal parameters can be e...

journal_title：Seminars in nuclear medicine

authors： Ash JM,Antico VF,Gilday DL,Houle S

更新日期：1982-10-01 00:00:00

abstract：:While 99mTc sulfur colloid imaging, because of its availability and convenience, remains the initial procedure of choice for spleen imaging, selective spleen scanning with damaged 99mTc-labeled RBCs can provide additional information in some cases. These cases include overlapping left hepatic lobe and suspected spleni...

journal_title：Seminars in nuclear medicine

authors： Armas RR

更新日期：1985-07-01 00:00:00

abstract：:In the past 20 years there have been great advances in our understanding of the molecular genetics of gastrointestinal tumors. In general, cancers develop and proliferate due to: driver mutations or related alterations in the genome resulting in overactivity of oncogenes, underactivity of tumor suppressor genes allowi...

journal_title：Seminars in nuclear medicine

authors： Wahl RL

更新日期：2020-09-01 00:00:00

abstract：:Molecular imaging has revolutionized clinical oncology by imaging-specific facets of cancer biology. Through noninvasive measurements of tumor physiology, targeted radiotracers can serve as biomarkers for disease characterization, prognosis, response assessment, and predicting long-term response/survival. In turn, the...

journal_title：Seminars in nuclear medicine

authors： Gillman JA,Pantel AR,Mankoff DA,Edmonds CE

更新日期：2020-11-01 00:00:00

abstract：:The high-level expression of somatostatin receptors (SSTR) on various tumor cells has provided the molecular basis for successful use of radiolabeled peptide analogues as tumor tracers in nuclear medicine. The vast majority of human tumors seem to overexpress one or the other of 5 distinct hSSTR subtype receptors. Whe...

journal_title：Seminars in nuclear medicine

authors： Virgolini I,Britton K,Buscombe J,Moncayo R,Paganelli G,Riva P

更新日期：2002-04-01 00:00:00

abstract：:New software methods that incorporate iterative reconstruction, resolution recovery, and noise compensation now provide the ability to maintain or improve myocardial perfusion SPECT image quality with conventional sodium iodide cameras. Despite lower image counting statistics associated with significantly decreased in...

journal_title：Seminars in nuclear medicine

authors： Gordon DePuey E 3rd

更新日期：2014-07-01 00:00:00

abstract：:Vital blue dyes were used to show the feasibility and accuracy of intraoperative lymphatic mapping of the sentinel node (SN) in patients with melanoma, breast cancer, and other solid tumors. Surgeons who have successfully completed an adequate number of cases of intraoperative mapping and sentinel lymph node dissectio...

journal_title：Seminars in nuclear medicine

authors： Bostick PJ,Giuliano AE

更新日期：2000-01-01 00:00:00

abstract：:Most positron emission tomography (PET) imaging studies in head and neck cancer are performed using the radiotracer 18-fluorodeoxyglucose ((18)FDG). PET with FDG has become a standard clinical imaging modality in patients with head and neck cancer. It contributes valuable information in localizing a primary tumor in p...

journal_title：Seminars in nuclear medicine

authors： Schöder H,Yeung HW

更新日期：2004-07-01 00:00:00

abstract：:In spite of localization of gallium in the lungs in a large variety of inflammatory pulmonary diseases, the chest radiograph is and will continue to be the principal diagnostic tool for evaluation of pulmonary inflammatory disease. The 67Ga-citrate scan, however, serves as a study complementary to chest radiography be...

journal_title：Seminars in nuclear medicine

authors： Bekerman C,Hoffer PB,Bitran JD,Gupta RG

更新日期：1980-07-01 00:00:00

abstract：:Heart transplantation is an effective and life-saving therapy for patients with end-stage heart disease. Cardiac allograft vasculopathy (CAV) is a frequent complication after heart transplantation and a leading cause of graft failure and death. The diffuse involvement of the coronary macro- and microvasculature in CAV...

journal_title：Seminars in nuclear medicine

authors： Chih S,Wiefels CC,Beanlands RSB

更新日期：2021-01-19 00:00:00

abstract：:Heart failure presents a significant problem in industrialized countries, with a high prevalence, morbidity, and mortality, where it is most frequently caused by coronary artery disease. Revascularization in patients with symptomatic heart failure has been associated with improved cardiovascular outcomes. Predictors o...

journal_title：Seminars in nuclear medicine

authors： Lim SP,Mc Ardle BA,Beanlands RS,Hessian RC

更新日期：2014-09-01 00:00:00

abstract：:99mTc-PYP myocardial scintigrams represent a means to detect and localize acute myocardial necrosis. These scintigrams are expected to be abnormal with acute myocardial infarcts of at least 3 grams in weight if serial imaging is utilized and proper attention to technique is provided. Any etiology of myocardial necrosi...

journal_title：Seminars in nuclear medicine

authors： Willerson JT,Parkey RW,Bonte FJ,Lewis SE,Corbett J,Buja LM

更新日期：1980-01-01 00:00:00

abstract：:A radionuclide procedure, hysterosalpingo-radionuclide scintigraphy (HERS), was designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries as well as to image and functionally outline the patency of the pathways between these two extremes of the female r...

journal_title：Seminars in nuclear medicine

authors： Iturralde M,Venter PF

更新日期：1981-10-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:Most of the components of the thrombotic and fibrinolytic systems have at some time been evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have been promising enough to emerge from investigational status to routine clinical use. New approaches are being explored, including improv...

journal_title：Seminars in nuclear medicine

authors： Knight LC

更新日期：1990-01-01 00:00:00

abstract：:FDG-PET/CT has an established role in the initial staging of locally advanced cervical cancers, particularly in evaluation of nodal disease and distant metastases. It is common practice to perform FDG-PET/CT 3 months postcompletion of chemoradiotherapy as it can predict outcome and be used to tailor management, includ...

journal_title：Seminars in nuclear medicine

authors： Gandy N,Arshad MA,Park WE,Rockall AG,Barwick TD

更新日期：2019-11-01 00:00:00

abstract：:Blood cell labeling with 99mTc has progressed through various developmental phases. In the case of red cell labeling, the science seems to have matured sufficiently, although minor refinements in the procedures will no doubt continue to be made. During the last 3 to 5 years, there has been a resurgence of interest in ...

journal_title：Seminars in nuclear medicine

authors： Srivastava SC,Straub RF

更新日期：1990-01-01 00:00:00

abstract：:Radiation and concurrent chemoradiation are essential in the treatment of head and neck cancers because they allow a potentially curative organ preservation approach in a manner that greatly affects quality of life. Greater doses of radiation to areas of gross disease have invariably led to greater loco-regional contr...

journal_title：Seminars in nuclear medicine

authors： Ahn PH,Garg MK

更新日期：2008-03-01 00:00:00

abstract：:Nuclear medicine procedures, including Ga-67 and labeled leucocyte SPECT/CT as well as PET/CT using 18F-FDG and recently Ga-68 tracers, have found extensive applications in the assessment of infectious and inflammatory processes in general and in soft tissues in particular. Recent published data focus on summarizing t...

journal_title：Seminars in nuclear medicine

authors： Arnon-Sheleg E,Israel O,Keidar Z

更新日期：2020-01-01 00:00:00

abstract：:Image registration is finding increased clinical use both in aiding diagnosis and guiding therapy. There are numerous algorithms for registration, which all involve maximizing a measure of similarity between a transformed floating image and a fixed reference image. The choice of the similarity measure depends, to some...

journal_title：Seminars in nuclear medicine

authors： Hutton BF,Braun M

更新日期：2003-07-01 00:00:00