The role of parmacologic manipulation in adrenal cortical scintigraphy.

abstract：:The results of quantitative analysis of planar thallium-201 stress scintigraphy are superior to those of visual analysis. The increased sensitivity for detection of coronary artery disease is associated with maintenance of specificity. Consequently, we believe that quantitative analysis is the state-of-the-art for pla...

journal_title：Seminars in nuclear medicine

authors： Wackers FJ,Fetterman RC,Mattera JA,Clements JP

更新日期：1985-01-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:2-deoxy-2-[18F] fluoro-D-glucose (18FDG) was developed in 1976 in a collaboration between scientists at the National Institutes of Health, the University of Pennsylvania, and Brookhaven National Laboratory. It was developed for the specific purpose of mapping brain glucose metabolism in living humans, thereby serving ...

journal_title：Seminars in nuclear medicine

authors： Fowler JS,Ido T

更新日期：2002-01-01 00:00:00

abstract：:This review describes general concepts with regard to radiopharmaceuticals for diagnostic or therapeutic applications that help to understand the specific challenges encountered during the design, (radio)synthesis, in vitro and in vivo evaluation and clinical translation of novel radiopharmaceuticals. The design of a ...

journal_title：Seminars in nuclear medicine

authors： Vermeulen K,Vandamme M,Bormans G,Cleeren F

更新日期：2019-09-01 00:00:00

abstract：:Recently, the lung has received increasing attention as a metabolic organ. In this role, the lung modulates the composition of the arterial blood by several mechanisms: removing active substances from the plasma, releasing substances into the plasma, temporarily holding substances from circulation, and activating or i...

journal_title：Seminars in nuclear medicine

authors： Touya JJ,Rahimian J,Corbus HF,Grubbs DE,Savala KM,Glass EC,Bennett LR

更新日期：1986-10-01 00:00:00

abstract：:In the early 1970s, when Seminars in Nuclear Medicine started publication, little was known about the quality of reporting in biomedical journals. Senior scholars were invited to become scientific editors of journals based on their research credibility and stature. Their knowledge of journalology (publication science)...

journal_title：Seminars in nuclear medicine

authors： Wilson M,Moher D

更新日期：2019-03-01 00:00:00

abstract：:The role of labeled tracers in radioimmunoassay procedures (RIA) and the advantages of the iodine-labeled antigens over 14C or tritium-labeled antigens are discussed. Different methods of labeling with iodine isotopes are presented. The ease with which microgram amounts of hormonal proteins are tagged, achieving high...

journal_title：Seminars in nuclear medicine

authors： Chervu LR,Murty DR

更新日期：1975-04-01 00:00:00

abstract：:The short range and high linear energy transfer of α-particles offer the potential for efficient tumor killing while sparing normal bystander cells. Hematologic malignancies are ideally suited to targeted α-particle therapy (TAT) due to easy accessibility of malignant cells in blood, bone marrow, lymph nodes, and sple...

journal_title：Seminars in nuclear medicine

authors： Jurcic JG

更新日期：2020-03-01 00:00:00

abstract：:Several antineuroblastoma monoclonal antibodies (MoAbs) have been described and two have been used in radioimmunoimaging and radioimmunotherapy in patients. MoAb 3F8 is a murine IgG3 antibody specific for the ganglioside GD2. Radioiodine-labeled 3F8 has been shown to specifically target human neuroblastoma in patients...

journal_title：Seminars in nuclear medicine

authors： Miraldi F

更新日期：1989-10-01 00:00:00

abstract：:While 99mTc sulfur colloid imaging, because of its availability and convenience, remains the initial procedure of choice for spleen imaging, selective spleen scanning with damaged 99mTc-labeled RBCs can provide additional information in some cases. These cases include overlapping left hepatic lobe and suspected spleni...

journal_title：Seminars in nuclear medicine

authors： Armas RR

更新日期：1985-07-01 00:00:00

abstract：:The convenience of (18)F-fluoride imaging is undeniable both because of its favorable tracer and because of its technical characteristics, including high image quality and short examination times leading to increased patient comfort. Depending on the activity administered, the radiation dose to patients is about compa...

journal_title：Seminars in nuclear medicine

authors： Fischer DR

更新日期：2013-11-01 00:00:00

abstract：:Rhenium-186 (tin)hydroxyethylidene diphosphonate (HEDP) is a new radiopharmaceutical that localizes in skeletal metastases in patients with advanced cancer. A single intravenous administration of approximately 34 mCi (1,258 MBq) resulted in significant improvement in pain in 33 of 43 evaluable patients (77%) following...

journal_title：Seminars in nuclear medicine

authors： Maxon HR 3rd,Thomas SR,Hertzberg VS,Schroder LE,Englaro EE,Samaratunga R,Scher HI,Moulton JS,Deutsch EA,Deutsch KF

更新日期：1992-01-01 00:00:00

abstract：:Sickling of erythrocytes in patients with S-hemoglobin causes marrow and bone infarction. The former can be demonstrated as a lack of 99mTc-sulfur colloid uptake on marrow imaging examination. These defects may resolve or persist long after the acute episode. If the bone is involved in the acute episode, imaging withi...

journal_title：Seminars in nuclear medicine

authors： Lutzker LG,Alavi A

更新日期：1976-01-01 00:00:00

abstract：:Much efficacy is gained in clinical practice if a single agent can be used for both diagnosis and therapy, a practice termed theranostics. Metaiodobenzylguanidine (mIBG), a norepinephrine analogue with high sensitivity and specificity for neuroblastoma, is an exemplar of theranostics. The physiologic biodistribution o...

journal_title：Seminars in nuclear medicine

authors： Parisi MT,Eslamy H,Park JR,Shulkin BL,Yanik GA

更新日期：2016-05-01 00:00:00

abstract：:The radioimmunoassay of digoxin is one of the most important services of the nuclear medicine laboratory. Precision and accuracy in the performance of the test are especially critical. A number of commerical kits are available and reliable. Pitfalls to be avoided includelimited availability or delay in performance of ...

journal_title：Seminars in nuclear medicine

authors： Shapiro B,Kollmann GJ,Heine WI

更新日期：1975-07-01 00:00:00

abstract：:New software methods that incorporate iterative reconstruction, resolution recovery, and noise compensation now provide the ability to maintain or improve myocardial perfusion SPECT image quality with conventional sodium iodide cameras. Despite lower image counting statistics associated with significantly decreased in...

journal_title：Seminars in nuclear medicine

authors： Gordon DePuey E 3rd

更新日期：2014-07-01 00:00:00

abstract：:The remarkable progress in immunologic techniques in the development of monoclonal antibodies offers the potential for powerful new tools for the detection of cardiovascular disorders, such as acute myocardial necrosis and acute deep venous thrombosis, in an accurate, safe, and noninvasive manner. Historically the use...

journal_title：Seminars in nuclear medicine

authors： Manspeaker P,Weisman HF,Schaible TF

更新日期：1993-04-01 00:00:00

abstract：:Ventilation/Perfusion (V/Q) positron emission tomography computed tomography (PET/CT) is now possible by substituting Technetium-99m (99mTc) with Gallium-68 (68Ga), using the same carrier molecules as conventional V/Q imaging. Ventilation imaging can be performed with 68Ga-carbon nanoparticles using the same synthesis...

journal_title：Seminars in nuclear medicine

authors： Le Roux PY,Hicks RJ,Siva S,Hofman MS

更新日期：2019-01-01 00:00:00

abstract：:Positron emission tomography (PET) using the radiotracer 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) can image cellular proliferation in human cancers in vivo. FLT uptake has been shown to correlate with pathology-based proliferation measurements, including the Ki-67 score, in a variety of human cancers. Unlike pathology...

journal_title：Seminars in nuclear medicine

authors： Salskov A,Tammisetti VS,Grierson J,Vesselle H

更新日期：2007-11-01 00:00:00

abstract：:The accumulation of radioactive tracer is associated with specific histological changes. Awareness of these changes permits a more specific interpretation of a positive bone scan, especially when correlating the radionuclide image with the plain radiographs. Increased uptake in the flow phase of an imaging study usual...

journal_title：Seminars in nuclear medicine

authors： McCarthy EF

更新日期：1997-10-01 00:00:00

abstract：:The use of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in prostate cancer depends on the phase of the disease along the natural history of this prevalent malignancy in men. Incidental high FDG uptake in the prostate gland, although rare, should prompt further investigation with at least a meas...

journal_title：Seminars in nuclear medicine

authors： Jadvar H

更新日期：2016-11-01 00:00:00

abstract：:Positron emission tomography (PET) makes it possible for the first time to examine in living humans the chemistry of the brain, which relates the structures of the brain to the functions of the mind. PET scans make it possible to assess the state of neurotransmitter receptors, such as the dopamine, serotonin, muscarin...

journal_title：Seminars in nuclear medicine

authors： Wagner HN Jr

更新日期：1986-01-01 00:00:00

abstract：:The radionuclide (99m)Tc-MDP bone scan is one of the most commonly performed nuclear medicine studies and helps in the diagnosis of different pathologies relating to the musculoskeletal system. With its increasing utility in clinical practice, it becomes more important to be aware of various limitations of this imagin...

journal_title：Seminars in nuclear medicine

authors： Agrawal K,Marafi F,Gnanasegaran G,Van der Wall H,Fogelman I

更新日期：2015-09-01 00:00:00

abstract：:The advent of simultaneous PET/MRI brought a large amount of possibilities in research and clinical applications into hybrid imaging. Unlike in PET/CT protocols, the MR component provides an almost unlimited number of pulse sequences and possibilities of different protocols in PET/MRI. Nevertheless, there is an impera...

journal_title：Seminars in nuclear medicine

authors： Barbosa Fde G,von Schulthess G,Veit-Haibach P

更新日期：2015-07-01 00:00:00

abstract：:Most positron emission tomography (PET) imaging studies in head and neck cancer are performed using the radiotracer 18-fluorodeoxyglucose ((18)FDG). PET with FDG has become a standard clinical imaging modality in patients with head and neck cancer. It contributes valuable information in localizing a primary tumor in p...

journal_title：Seminars in nuclear medicine

authors： Schöder H,Yeung HW

更新日期：2004-07-01 00:00:00

abstract：:Graft infection following prosthetic vascular reconstruction is an uncommon but severe complication. The clinical presentation is often subtle and nonspecific and may occur long after surgery. Although defining a prosthetic vascular graft infection can be difficult, early diagnosis and treatment are essential for the ...

journal_title：Seminars in nuclear medicine

authors： Keidar Z,Nitecki S

更新日期：2013-09-01 00:00:00

abstract：:This review describes the use of monoclonal antibodies (MoAbs) for immunoscintigraphic detection of thrombosis and thromboembolism. Two major groups of MoAbs have been tested: Antibodies directed against platelets and antibodies directed against fibrin. Several antiplatelet antibodies have been developed that are dire...

journal_title：Seminars in nuclear medicine

authors： Koblik PD,De Nardo GL,Berger HJ

更新日期：1989-07-01 00:00:00

abstract：:In order to assess the role of 99mTc-iminodiacetic acid (IDA) cholescintigraphy in evaluating postoperative patients, a total of 213 studies were performed in 189 patients over a 3-year time period. Of these, 130 studies were obtained in 125 cases with signs and/or symptoms suggesting postcholecystectomy syndrome. A n...

journal_title：Seminars in nuclear medicine

authors： Weissmann HS,Gliedman ML,Wilk PJ,Sugarman LA,Badia J,Guglielmo K,Freeman LM

更新日期：1982-01-01 00:00:00

abstract：:The best option for the treatment of end-stage renal disease is kidney transplantation. Prompt diagnosis and management of early posttransplantation complications is of utmost importance for graft survival. Biochemical markers, allograft biopsies, and imaging modalities are used for the timely recognition and manageme...

journal_title：Seminars in nuclear medicine

authors： Aktaş A

更新日期：2014-03-01 00:00:00

abstract：:Radionuclide renal studies are particularly well suited to pediatrics as renal problems in children usually are part of a dynamic process which requires serial assessment. The absence of side-effects and the low radiation dose has added to their popularity in pediatrics. A number of different renal parameters can be e...

journal_title：Seminars in nuclear medicine

authors： Ash JM,Antico VF,Gilday DL,Houle S

更新日期：1982-10-01 00:00:00