Pitfalls in the application of digoxin determinations.

abstract：:There seems little doubt that the ability to prepare antibodies with a unique specificity for surface tumor antigens will have a tremendous usefulness in the diagnostic and therapeutics of cancer. This usefulness will be wide-ranged when the antibodies are labeled with radioisotopes as tools for screening for primary ...

journal_title：Seminars in nuclear medicine

authors： Spar IL

更新日期：1976-10-01 00:00:00

abstract：:Monoclonal antibody (MoAb) imaging has contributed greatly to the diagnosis and staging of both colorectal and ovarian cancers, and recently has been tested in patients with prostate cancer. Anatomic imaging modalities such as computed tomography, ultrasound, and magnetic resonance imaging have deficiencies in imaging...

journal_title：Seminars in nuclear medicine

authors： Neal CE,Meis LC

更新日期：1994-10-01 00:00:00

abstract：:While 99mTc sulfur colloid imaging, because of its availability and convenience, remains the initial procedure of choice for spleen imaging, selective spleen scanning with damaged 99mTc-labeled RBCs can provide additional information in some cases. These cases include overlapping left hepatic lobe and suspected spleni...

journal_title：Seminars in nuclear medicine

authors： Armas RR

更新日期：1985-07-01 00:00:00

abstract：:Recently, the lung has received increasing attention as a metabolic organ. In this role, the lung modulates the composition of the arterial blood by several mechanisms: removing active substances from the plasma, releasing substances into the plasma, temporarily holding substances from circulation, and activating or i...

journal_title：Seminars in nuclear medicine

authors： Touya JJ,Rahimian J,Corbus HF,Grubbs DE,Savala KM,Glass EC,Bennett LR

更新日期：1986-10-01 00:00:00

abstract：:The evaluation of primary brain tumor is challenging. Neuroimaging plays a significant role. At diagnosis, imaging is needed to establish a differential diagnosis, provide prognostic information, as well as direct biopsy. After the initial treatment, imaging is needed to distinguish recurrent disease from treatment-re...

journal_title：Seminars in nuclear medicine

authors： Chen W,Silverman DH

更新日期：2008-07-01 00:00:00

abstract：:Breast cancer is the most common cause of bone metastases in women. Imaging studies are useful to identify bone involvement and associated complications, for follow-up of disease spread and for the assessment of response to therapy. Bone scintigraphy with (99m)technetium-labeled diphosphonates is most widely used, due...

journal_title：Seminars in nuclear medicine

authors： Ben-Haim S,Israel O

更新日期：2009-11-01 00:00:00

abstract：:Most of the components of the thrombotic and fibrinolytic systems have at some time been evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have been promising enough to emerge from investigational status to routine clinical use. New approaches are being explored, including improv...

journal_title：Seminars in nuclear medicine

authors： Knight LC

更新日期：1990-01-01 00:00:00

abstract：:Evaluation of ventricular performance is essential in the diagnosis and long-term management of patients with heart disease. This can be most easily performed clinically using simple tools. When more definitive objective assessment of cardiac function is indicated, the equilibrium gated blood pool study provides relia...

journal_title：Seminars in nuclear medicine

authors： Strauss HW,McKusick KA,Boucher CA,Bingham JB,Pohost GM

更新日期：1979-10-01 00:00:00

abstract：:Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are now more and more available for clinical use. PET/MR combines the unique features of MR including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as we...

journal_title：Seminars in nuclear medicine

authors： Sollini M,Berchiolli R,Kirienko M,Rossi A,Glaudemans AWJM,Slart R,Erba PA

更新日期：2018-05-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:Long-awaited results from randomized clinical trials designed to test the validity of sentinel lymph node biopsy (SLNB) as replacement of axillary lymph node dissection (ALND) in management of early breast cancer have recently been published. All the trials conclude SLNB has survival rates comparable to those of ALND ...

journal_title：Seminars in nuclear medicine

authors： Moncayo VM,Aarsvold JN,Grant SF,Bartley SC,Alazraki NP

更新日期：2013-07-01 00:00:00

abstract：:Identification of patients with renovascular hypertension (RVH) among the larger group of patients with essential hypertension has been aided by a wide variety of in vitro and in vivo nuclear medicine procedures. The most valuable in vitro procedure remains the radioimmunoassay (RIA) for renin activity obtained from i...

journal_title：Seminars in nuclear medicine

authors： Fine EJ,Sarkar S

更新日期：1989-04-01 00:00:00

abstract：:Radioimmunotherapy is a promising new therapeutic option for the treatment of B-cell non-Hodgkin's lymphoma. Several monoclonal antibody and radionuclide conjugates, including I-131 tositumomab and Y-90 ibritumomab, have been investigated in clinical trials. Yttrium 90 ibritumomab tiuxetan (Zevalin; Biogen Idec Inc, C...

journal_title：Seminars in nuclear medicine

authors： Zimmer AM

更新日期：2004-01-01 00:00:00

abstract：:Prospective delineation of viable from nonviable myocardium in patients with coronary artery disease in an important factor in deciding whether a patient should be revascularized or treated medically. Two common techniques--single-photon emission computed tomography (SPECT) and positron-emission computed tomography (P...

journal_title：Seminars in nuclear medicine

authors： Saha GB,MacIntyre WJ,Brunken RC,Go RT,Raja S,Wong CO,Chen EQ

更新日期：1996-10-01 00:00:00

abstract：:Radioimmunotherapy is a form of targeted radionuclide therapy that uses a monoclonal antibody to deliver localized radiation. It is most appropriate for treatment of multiple tumor sites that cannot be readily excised surgically or irradiated using external beam radiation or brachytherapy. At present, 2 products, Bexx...

journal_title：Seminars in nuclear medicine

authors： Goldsmith SJ

更新日期：2010-03-01 00:00:00

abstract：:Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...

journal_title：Seminars in nuclear medicine

authors： Hofman MS,Hicks RJ

更新日期：2016-09-01 00:00:00

abstract：:The definition of tumor involved volumes in patients with head and neck cancer poses great challenges with the increasing use of highly conformal radiotherapy techniques eg, volumetric modulated arc therapy and intensity modulated proton therapy. The risk of underdosing the tumor might increase unless great care is ta...

journal_title：Seminars in nuclear medicine

authors： Jensen K,Al-Farra G,Dejanovic D,Eriksen JG,Loft A,Hansen CR,Pameijer FA,Zukauskaite R,Grau C

更新日期：2021-01-01 00:00:00

abstract：:Graft infection following prosthetic vascular reconstruction is an uncommon but severe complication. The clinical presentation is often subtle and nonspecific and may occur long after surgery. Although defining a prosthetic vascular graft infection can be difficult, early diagnosis and treatment are essential for the ...

journal_title：Seminars in nuclear medicine

authors： Keidar Z,Nitecki S

更新日期：2013-09-01 00:00:00

abstract：:The radionuclide bone scan is one of the most commonly performed pediatric nuclear medicine procedures. Bone scintigraphy is used as the diagnostic procedure of choice for diagnosis of bone and soft-tissue infection and can aid in the diagnosis of occult trauma without radiographic findings. There is a complimentary r...

journal_title：Seminars in nuclear medicine

authors： Nadel HR

更新日期：2007-09-01 00:00:00

abstract：:Positron emission tomography (PET) of local cerebral glucose utilization is highly sensitive in detecting epileptogenic regions that correspond to electrographic localization in patients with epilepsy. In medically refractory temporal lobe epilepsy for which surgical resection of the epileptogenic zone is a therapeuti...

journal_title：Seminars in nuclear medicine

authors： Chugani HT

更新日期：1992-10-01 00:00:00

abstract：:Rhenium-186 (tin)hydroxyethylidene diphosphonate (HEDP) is a new radiopharmaceutical that localizes in skeletal metastases in patients with advanced cancer. A single intravenous administration of approximately 34 mCi (1,258 MBq) resulted in significant improvement in pain in 33 of 43 evaluable patients (77%) following...

journal_title：Seminars in nuclear medicine

authors： Maxon HR 3rd,Thomas SR,Hertzberg VS,Schroder LE,Englaro EE,Samaratunga R,Scher HI,Moulton JS,Deutsch EA,Deutsch KF

更新日期：1992-01-01 00:00:00

abstract：:Vital blue dyes were used to show the feasibility and accuracy of intraoperative lymphatic mapping of the sentinel node (SN) in patients with melanoma, breast cancer, and other solid tumors. Surgeons who have successfully completed an adequate number of cases of intraoperative mapping and sentinel lymph node dissectio...

journal_title：Seminars in nuclear medicine

authors： Bostick PJ,Giuliano AE

更新日期：2000-01-01 00:00:00

abstract：:Uneven distribution of ventilation, or ventilation heterogeneity, has been observed in asthma for over 60 years using multiple breath nitrogen washout (MBNW) studies. Ventilation heterogeneity has been known to predict airway hyperresponsiveness (the ability of the airways to constrict too easily and by too much) in a...

journal_title：Seminars in nuclear medicine

authors： Farrow C,King G

更新日期：2019-01-01 00:00:00

abstract：:The convenience of (18)F-fluoride imaging is undeniable both because of its favorable tracer and because of its technical characteristics, including high image quality and short examination times leading to increased patient comfort. Depending on the activity administered, the radiation dose to patients is about compa...

journal_title：Seminars in nuclear medicine

authors： Fischer DR

更新日期：2013-11-01 00:00:00

abstract：:FDG-PET/CT has an established role in the initial staging of locally advanced cervical cancers, particularly in evaluation of nodal disease and distant metastases. It is common practice to perform FDG-PET/CT 3 months postcompletion of chemoradiotherapy as it can predict outcome and be used to tailor management, includ...

journal_title：Seminars in nuclear medicine

authors： Gandy N,Arshad MA,Park WE,Rockall AG,Barwick TD

更新日期：2019-11-01 00:00:00

abstract：:Nuclear medicine imaging techniques continue to play a unique role in the evaluation of hepatic masses. Although many useful radiodiagnostic agents are available, the predominant nuclear medicine study used to evaluate hepatic masses in this decade is technetium-labeled red blood cell "blood-pool" scintigraphy. Hepati...

journal_title：Seminars in nuclear medicine

authors： Middleton ML

更新日期：1996-01-01 00:00:00

abstract：:Radiolabeling of red cells and their clinical and research application in nuclear medicine constitute an area of continued interest and steady growth during the past two decades. Significant advances have been made so that at the present time, radiolabels with sufficient in vitro and in vivo stability are available fo...

journal_title：Seminars in nuclear medicine

authors： Srivastava SC,Chervu LR

更新日期：1984-04-01 00:00:00

abstract：:Positron emission tomography (PET) scanning has been a powerful research tool since its inception. Changes in the marketplace that have allowed PET to move into the clinical environment include the commercial availability of appropriate radiopharmaceuticals, reimbursement of procedures by insurance companies, and incr...

journal_title：Seminars in nuclear medicine

authors： Lissak RJ

更新日期：2000-10-01 00:00:00

abstract：:Neurochemical imaging is one of the most established "molecular" imaging techniques. There have been tremendous efforts expended to develop radioligands specific to each neurochemical system. Investigational applications of neurochemical imaging in dementing disorders are extensive. Cholinergic, dopaminergic, and sero...

journal_title：Seminars in nuclear medicine

authors： Minoshima S,Frey KA,Cross DJ,Kuhl DE

更新日期：2004-01-01 00:00:00

abstract：:This review describes general concepts with regard to radiopharmaceuticals for diagnostic or therapeutic applications that help to understand the specific challenges encountered during the design, (radio)synthesis, in vitro and in vivo evaluation and clinical translation of novel radiopharmaceuticals. The design of a ...

journal_title：Seminars in nuclear medicine

authors： Vermeulen K,Vandamme M,Bormans G,Cleeren F

更新日期：2019-09-01 00:00:00