The use of positron emission tomography in the clinical assessment of epilepsy.

abstract：:Positron emission tomography (PET)/computed tomography (CT) is a rapidly expanding imaging modality, thanks to the availability of compact medical cyclotrons and automated chemistry synthesis modules for the production of PET radiopharmaceuticals. Despite the availability of many radiotracers, [(18)F]fluorodeoxyglucos...

journal_title：Seminars in nuclear medicine

authors： Vallabhajosula S,Solnes L,Vallabhajosula B

更新日期：2011-07-01 00:00:00

abstract：:The definition of tumor involved volumes in patients with head and neck cancer poses great challenges with the increasing use of highly conformal radiotherapy techniques eg, volumetric modulated arc therapy and intensity modulated proton therapy. The risk of underdosing the tumor might increase unless great care is ta...

journal_title：Seminars in nuclear medicine

authors： Jensen K,Al-Farra G,Dejanovic D,Eriksen JG,Loft A,Hansen CR,Pameijer FA,Zukauskaite R,Grau C

更新日期：2021-01-01 00:00:00

abstract：:Computer processing can improve the quality of scintigrams in several ways. It can increase the accuracy with which the image approximates the activity distribution by reversing degradation. It can selectively enhance normal or abnormal structures of interest. It can optimize the use of the display system presenting t...

journal_title：Seminars in nuclear medicine

authors： Pizer SM,Todd-Pokropek AE

更新日期：1978-04-01 00:00:00

abstract：:In epilepsy, a detailed history, blood chemistry, routine electroencephalography, and brain MRI are important for the diagnosis of seizure type or epilepsy syndrome for the decision of appropriate drug treatment. Although antiepileptic drugs are mostly successful for controlling epileptic seizures, 20%-30% patients ar...

journal_title：Seminars in nuclear medicine

authors： Ergün EL,Saygi S,Yalnizoglu D,Oguz KK,Erbas B

更新日期：2016-07-01 00:00:00

abstract：:Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are now more and more available for clinical use. PET/MR combines the unique features of MR including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as we...

journal_title：Seminars in nuclear medicine

authors： Sollini M,Berchiolli R,Kirienko M,Rossi A,Glaudemans AWJM,Slart R,Erba PA

更新日期：2018-05-01 00:00:00

abstract：:Although planar radionuclide techniques provide accurate, noninvasive measurements of myocardial perfusion and function that are of proven clinical value in the evaluation of the cardiac patient, they are limited by poor object contrast and superimposition of surrounding structures. Due to incomplete angular sampling ...

journal_title：Seminars in nuclear medicine

authors： Cerqueira MD,Harp GD,Ritchie JL

更新日期：1987-07-01 00:00:00

abstract：:Identification of patients with renovascular hypertension (RVH) among the larger group of patients with essential hypertension has been aided by a wide variety of in vitro and in vivo nuclear medicine procedures. The most valuable in vitro procedure remains the radioimmunoassay (RIA) for renin activity obtained from i...

journal_title：Seminars in nuclear medicine

authors： Fine EJ,Sarkar S

更新日期：1989-04-01 00:00:00

abstract：:The advantage of immunoscintigraphy over autologous leukocyte techniques in the imaging of infection is the simplicity of its use compared with techniques that require the isolation of autologous white blood cells. The advantage over 99mTc- or 111In-labeled nonspecific human immunoglobulin is the excellent target-to-b...

journal_title：Seminars in nuclear medicine

authors： Becker W,Goldenberg DM,Wolf F

更新日期：1994-04-01 00:00:00

abstract：:Concern about the spread of infections in the hospital setting has prompted regulatory agencies to mandate infection control standards. Each hospital department is required to have written policies and procedures which describe measures to prevent and control the spread of nosocomial infections (hospital acquired infe...

journal_title：Seminars in nuclear medicine

authors： Adams A,Egan A

更新日期：1988-10-01 00:00:00

abstract：:Due to the increasing life expectancy, the diagnosis of malignancy and treatment of elderly patients is becoming more common. Prostate cancer is particularly frequent in this setting. Many different approaches are now available, but some of them imply significant risks or collateral effects. In those patients an accur...

journal_title：Seminars in nuclear medicine

authors： Castellucci P,Nanni C,Ambrosini V

更新日期：2018-11-01 00:00:00

abstract：:Most of the components of the thrombotic and fibrinolytic systems have at some time been evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have been promising enough to emerge from investigational status to routine clinical use. New approaches are being explored, including improv...

journal_title：Seminars in nuclear medicine

authors： Knight LC

更新日期：1990-01-01 00:00:00

abstract：:Detection of acute myocardial infarction as an area of increased activity has intrigued investigators for some time. Initial attempts with 203Hg-chlormerodrin and 203Hg-fluorescein analogues were successful in man. More recently, however, successful imaging of the acute myocardial infarct has been achieved with severa...

journal_title：Seminars in nuclear medicine

authors： Holman BL,Davis MA,Hanson RN

更新日期：1977-01-01 00:00:00

abstract：:Several antineuroblastoma monoclonal antibodies (MoAbs) have been described and two have been used in radioimmunoimaging and radioimmunotherapy in patients. MoAb 3F8 is a murine IgG3 antibody specific for the ganglioside GD2. Radioiodine-labeled 3F8 has been shown to specifically target human neuroblastoma in patients...

journal_title：Seminars in nuclear medicine

authors： Miraldi F

更新日期：1989-10-01 00:00:00

abstract：:One of the major mechanisms of implementing the International Atomic Energy Agency's (IAEA) programs in nuclear medicine has been through coordinated research projects (CRPs). In recent years, the IAEA has initiated a new type of CRP, called Doctoral CRP, in an attempt to further improve the effectiveness of its progr...

journal_title：Seminars in nuclear medicine

authors： Padhy AK,Dondi M

更新日期：2008-03-01 00:00:00

abstract：:Autonomic innervation plays an important role in proper functioning of the cardiovascular system. Altered cardiac sympathetic function is present in a variety of diseases, and can be assessed with radionuclide imaging using sympathetic neurotransmitter analogues. The most studied adrenergic radiotracer is cardiac 123I...

journal_title：Seminars in nuclear medicine

authors： Wan N,Travin MI

更新日期：2020-07-01 00:00:00

abstract：:The high-level expression of somatostatin receptors (SSTR) on various tumor cells has provided the molecular basis for successful use of radiolabeled peptide analogues as tumor tracers in nuclear medicine. The vast majority of human tumors seem to overexpress one or the other of 5 distinct hSSTR subtype receptors. Whe...

journal_title：Seminars in nuclear medicine

authors： Virgolini I,Britton K,Buscombe J,Moncayo R,Paganelli G,Riva P

更新日期：2002-04-01 00:00:00

abstract：:Regional cerebral blood flow (rCBF) findings and their application to cerebrovascular disease are reviewed. Although the coupling of cerebral blood flow and metabolism are best studied with positron emission tomography, single-photon emission computed tomography measurements of rCBF can contribute to patient managemen...

journal_title：Seminars in nuclear medicine

authors： Hellman RS,Tikofsky RS

更新日期：1990-10-01 00:00:00

abstract：:Radioimmunotherapy is a promising new therapeutic option for the treatment of B-cell non-Hodgkin's lymphoma. Several monoclonal antibody and radionuclide conjugates, including I-131 tositumomab and Y-90 ibritumomab, have been investigated in clinical trials. Yttrium 90 ibritumomab tiuxetan (Zevalin; Biogen Idec Inc, C...

journal_title：Seminars in nuclear medicine

authors： Zimmer AM

更新日期：2004-01-01 00:00:00

abstract：:FDG-PET/CT has an established role in the initial staging of locally advanced cervical cancers, particularly in evaluation of nodal disease and distant metastases. It is common practice to perform FDG-PET/CT 3 months postcompletion of chemoradiotherapy as it can predict outcome and be used to tailor management, includ...

journal_title：Seminars in nuclear medicine

authors： Gandy N,Arshad MA,Park WE,Rockall AG,Barwick TD

更新日期：2019-11-01 00:00:00

abstract：:There seems little doubt that the ability to prepare antibodies with a unique specificity for surface tumor antigens will have a tremendous usefulness in the diagnostic and therapeutics of cancer. This usefulness will be wide-ranged when the antibodies are labeled with radioisotopes as tools for screening for primary ...

journal_title：Seminars in nuclear medicine

authors： Spar IL

更新日期：1976-10-01 00:00:00

abstract：:Radionuclide renal studies are particularly well suited to pediatrics as renal problems in children usually are part of a dynamic process which requires serial assessment. The absence of side-effects and the low radiation dose has added to their popularity in pediatrics. A number of different renal parameters can be e...

journal_title：Seminars in nuclear medicine

authors： Ash JM,Antico VF,Gilday DL,Houle S

更新日期：1982-10-01 00:00:00

abstract：:The diphosphonate bone scan is ideally suited to assess many global, focal or multifocal metabolic bone disorders and there remains a role for conventional bone scintigraphy in metabolic bone disorders at diagnosis, investigation of complications, and treatment response assessment. In contrast, the role of bone scinti...

journal_title：Seminars in nuclear medicine

authors： Cook GJ,Gnanasegaran G,Chua S

更新日期：2010-01-01 00:00:00

abstract：:The evaluation of primary brain tumor is challenging. Neuroimaging plays a significant role. At diagnosis, imaging is needed to establish a differential diagnosis, provide prognostic information, as well as direct biopsy. After the initial treatment, imaging is needed to distinguish recurrent disease from treatment-re...

journal_title：Seminars in nuclear medicine

authors： Chen W,Silverman DH

更新日期：2008-07-01 00:00:00

abstract：:The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s. Today, despite the many advances in imaging instrumentation, radiopharmaceuticals, and methodology over these years, cholescintigraphy still plays an important role in confirming or excl...

journal_title：Seminars in nuclear medicine

authors： Ziessman HA

更新日期：2003-10-01 00:00:00

abstract：:Prospective delineation of viable from nonviable myocardium in patients with coronary artery disease in an important factor in deciding whether a patient should be revascularized or treated medically. Two common techniques--single-photon emission computed tomography (SPECT) and positron-emission computed tomography (P...

journal_title：Seminars in nuclear medicine

authors： Saha GB,MacIntyre WJ,Brunken RC,Go RT,Raja S,Wong CO,Chen EQ

更新日期：1996-10-01 00:00:00

abstract：:According to SEER Cancer Statistics Review there are around 165,000 new prostate cancer cases estimated in 2018 accounting for 9.5% of all newly diagnosed cancers. Accurate staging of primary prostate cancer is important for therapy selection (local vs systemic). Recent developments in molecular imaging may significan...

journal_title：Seminars in nuclear medicine

authors： Pomykala KL,Farolfi A,Hadaschik B,Fendler WP,Herrmann K

更新日期：2019-07-01 00:00:00

abstract：:The radionuclide (99m)Tc-MDP bone scan is one of the most commonly performed nuclear medicine studies and helps in the diagnosis of different pathologies relating to the musculoskeletal system. With its increasing utility in clinical practice, it becomes more important to be aware of various limitations of this imagin...

journal_title：Seminars in nuclear medicine

authors： Agrawal K,Marafi F,Gnanasegaran G,Van der Wall H,Fogelman I

更新日期：2015-09-01 00:00:00

abstract：:In this work, the methods of the Prospective Investigation of Pulmonary Embolism Diagnosis III (PIOPED III) are described in detail. PIOPED III is a multicenter collaborative investigation sponsored by the National Heart, Lung and Blood Institute. The purpose is to determine the accuracy of gadolinium-enhanced magneti...

journal_title：Seminars in nuclear medicine

authors： Stein PD,Gottschalk A,Sostman HD,Chenevert TL,Fowler SE,Goodman LR,Hales CA,Hull RD,Kanal E,Leeper KV Jr,Nadich DP,Sak DJ,Tapson VF,Wakefield TW,Weg JG,Woodard PK

更新日期：2008-11-01 00:00:00

abstract：:Breast cancer is the most common cause of bone metastases in women. Imaging studies are useful to identify bone involvement and associated complications, for follow-up of disease spread and for the assessment of response to therapy. Bone scintigraphy with (99m)technetium-labeled diphosphonates is most widely used, due...

journal_title：Seminars in nuclear medicine

authors： Ben-Haim S,Israel O

更新日期：2009-11-01 00:00:00

abstract：:Radiation and concurrent chemoradiation are essential in the treatment of head and neck cancers because they allow a potentially curative organ preservation approach in a manner that greatly affects quality of life. Greater doses of radiation to areas of gross disease have invariably led to greater loco-regional contr...

journal_title：Seminars in nuclear medicine

authors： Ahn PH,Garg MK

更新日期：2008-03-01 00:00:00