Abstract:
:Positron emission tomography (PET) scanning has been a powerful research tool since its inception. Changes in the marketplace that have allowed PET to move into the clinical environment include the commercial availability of appropriate radiopharmaceuticals, reimbursement of procedures by insurance companies, and increasing awareness of physicians of the benefits of PET. Facilities that are interested in clinical PET need to develop a process to purchase equipment with an appropriate business plan. This is necessary to assure financial viability and to convince hospital administrators of the viability. The creation of a successful PET program requires an understanding of all aspects relating to a center. The process begins with reviewing the mission statement of the facility. The next step is to prepare the feasibility study, which includes reviewing the existing marketplace and determining the volume, level of referring physicians' interest, and availability of radiopharmaceuticals. Finally, an appropriate pro forma needs to be constructed to facilitate the final decision concerning the potential financial viability of such an endeavor.
journal_name
Semin Nucl Medjournal_title
Seminars in nuclear medicineauthors
Lissak RJdoi
10.1053/snuc.2000.9544subject
Has Abstractpub_date
2000-10-01 00:00:00pages
299-305issue
4eissn
0001-2998issn
1558-4623pii
S0001-2998(00)80030-6journal_volume
30pub_type
杂志文章abstract::The use of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in prostate cancer depends on the phase of the disease along the natural history of this prevalent malignancy in men. Incidental high FDG uptake in the prostate gland, although rare, should prompt further investigation with at least a meas...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2016.07.004
更新日期:2016-11-01 00:00:00
abstract::Computer processing can improve the quality of scintigrams in several ways. It can increase the accuracy with which the image approximates the activity distribution by reversing degradation. It can selectively enhance normal or abnormal structures of interest. It can optimize the use of the display system presenting t...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(78)80036-1
更新日期:1978-04-01 00:00:00
abstract::When serious infections are suspected, patients are often treated empirically with broad-spectrum antibiotics while awaiting results that provide information on the bacterial class and species causing the infection, as well as drug susceptibilities. For deep-seated infections, these traditional diagnostic techniques o...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2017.11.003
更新日期:2018-03-01 00:00:00
abstract::Nuclear medicine procedures, including Ga-67 and labeled leucocyte SPECT/CT as well as PET/CT using 18F-FDG and recently Ga-68 tracers, have found extensive applications in the assessment of infectious and inflammatory processes in general and in soft tissues in particular. Recent published data focus on summarizing t...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2019.07.005
更新日期:2020-01-01 00:00:00
abstract::Positron emission tomography (PET) using the radiotracer 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) can image cellular proliferation in human cancers in vivo. FLT uptake has been shown to correlate with pathology-based proliferation measurements, including the Ki-67 score, in a variety of human cancers. Unlike pathology...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2007.08.001
更新日期:2007-11-01 00:00:00
abstract::Radiation and concurrent chemoradiation are essential in the treatment of head and neck cancers because they allow a potentially curative organ preservation approach in a manner that greatly affects quality of life. Greater doses of radiation to areas of gross disease have invariably led to greater loco-regional contr...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2007.11.002
更新日期:2008-03-01 00:00:00
abstract::The role of labeled tracers in radioimmunoassay procedures (RIA) and the advantages of the iodine-labeled antigens over 14C or tritium-labeled antigens are discussed. Different methods of labeling with iodine isotopes are presented. The ease with which microgram amounts of hormonal proteins are tagged, achieving high...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(75)80030-4
更新日期:1975-04-01 00:00:00
abstract::Heart transplantation is an effective and life-saving therapy for patients with end-stage heart disease. Cardiac allograft vasculopathy (CAV) is a frequent complication after heart transplantation and a leading cause of graft failure and death. The diffuse involvement of the coronary macro- and microvasculature in CAV...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2020.12.010
更新日期:2021-01-19 00:00:00
abstract::The diphosphonate bone scan is ideally suited to assess many global, focal or multifocal metabolic bone disorders and there remains a role for conventional bone scintigraphy in metabolic bone disorders at diagnosis, investigation of complications, and treatment response assessment. In contrast, the role of bone scinti...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2009.08.002
更新日期:2010-01-01 00:00:00
abstract::The introduction of in vivo imaging of Aβ-amyloid (Αβ) pathology more than a decade ago, transformed the assessment of Alzheimer disease (AD) allowing the evaluation of Aβ deposition over time by providing highly accurate, reliable, and reproducible quantitative statements of regional or global Aβ burden in the brain ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2016.09.006
更新日期:2017-01-01 00:00:00
abstract::Epilepsy is the most common serious brain disorder in children, occurring in all parts of the world and within every stratum of the population. Through its effects, it exerts a significant physical, psychological, economic, and social toll on children and their caregivers. Historically, the surgical treatment of epile...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2012.06.005
更新日期:2012-11-01 00:00:00
abstract::New software methods that incorporate iterative reconstruction, resolution recovery, and noise compensation now provide the ability to maintain or improve myocardial perfusion SPECT image quality with conventional sodium iodide cameras. Despite lower image counting statistics associated with significantly decreased in...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2014.04.001
更新日期:2014-07-01 00:00:00
abstract::Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigr...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80112-6
更新日期:1993-10-01 00:00:00
abstract::Suspecting and diagnosing venous thrombosis and pulmonary embolism remain major clinical problems. For a variety of reasons, including the patient's pre-existing cardiac and pulmonary status and the release of humoral mediators, pulmonary emboli evoke varied responses in different patients. Symptoms and signs of pulmo...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80131-x
更新日期:1991-10-01 00:00:00
abstract::FDG is a tracer for visualizing glucose metabolism. PET/CT using FDG is widely used for the diagnosis of cancer, because glycolysis is elevated in cancer cells. Similarly, active inflammatory tissue also exhibits elevated glucose metabolism because of glycolysis in activated macrophages and proliferating fibroblasts. ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2017.02.005
更新日期:2017-07-01 00:00:00
abstract::In the 1980s, the (111)In-labeled somatostatin analog OctreoScan (Covidien, Hazelwood, MO) was developed for imaging of somatostatin receptor subtype 2 (sst(2)) overexpressing tumors. On the basis of this success, peptide receptor radionuclide therapy (PRRT) was developed using similar somatostatin analogs with differ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2009.12.001
更新日期:2010-05-01 00:00:00
abstract::Heart failure presents a significant problem in industrialized countries, with a high prevalence, morbidity, and mortality, where it is most frequently caused by coronary artery disease. Revascularization in patients with symptomatic heart failure has been associated with improved cardiovascular outcomes. Predictors o...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2014.07.003
更新日期:2014-09-01 00:00:00
abstract::The basic principles of the use of radiation dosimetry in nuclear medicine are reviewed. The basic structure of the main mathematical equations are given and formal dosimetry systems are discussed. An extensive overview of the history and current status of anthropomorphic models (phantoms) is given. The sources and ma...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2014.03.008
更新日期:2014-05-01 00:00:00
abstract::We describe our all-digital, filmless, department of nuclear medicine, which has been fully operational for 3 years. The approach to the design and implementation of a nuclear medicine picture archiving and communication system (PACS) is discussed, as well as enhancements found to be necessary or desirable during our ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(05)80031-5
更新日期:1990-07-01 00:00:00
abstract::Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are now more and more available for clinical use. PET/MR combines the unique features of MR including excellent soft tissue contrast, diffusion-weighted imaging, dynamic contrast-enhanced imaging, fMRI and other specialized sequences as we...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2018.02.003
更新日期:2018-05-01 00:00:00
abstract::Prostate cancer remains an important and growing health problem. Advances in imaging of prostate cancer may help to achieve earlier and more accurate diagnosis and treatment. We review the various strategies using reporter genes for molecular imaging of prostate cancer. These approaches are emerging as valuable tools ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2007.09.002
更新日期:2008-01-01 00:00:00
abstract::Graft infection following prosthetic vascular reconstruction is an uncommon but severe complication. The clinical presentation is often subtle and nonspecific and may occur long after surgery. Although defining a prosthetic vascular graft infection can be difficult, early diagnosis and treatment are essential for the ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2013.04.004
更新日期:2013-09-01 00:00:00
abstract::The remarkable progress in immunologic techniques in the development of monoclonal antibodies offers the potential for powerful new tools for the detection of cardiovascular disorders, such as acute myocardial necrosis and acute deep venous thrombosis, in an accurate, safe, and noninvasive manner. Historically the use...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(05)80094-7
更新日期:1993-04-01 00:00:00
abstract::Most positron emission tomography (PET) imaging studies in head and neck cancer are performed using the radiotracer 18-fluorodeoxyglucose ((18)FDG). PET with FDG has become a standard clinical imaging modality in patients with head and neck cancer. It contributes valuable information in localizing a primary tumor in p...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2004.03.004
更新日期:2004-07-01 00:00:00
abstract::The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s. Today, despite the many advances in imaging instrumentation, radiopharmaceuticals, and methodology over these years, cholescintigraphy still plays an important role in confirming or excl...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1016/s0001-2998(03)00032-1
更新日期:2003-10-01 00:00:00
abstract::More than 7 million stress perfusion studies are performed in the United States annually, 44% with pharmacological vasodilator stress agents. Both adenosine and dipyridamole are nonselective coronary vasodilators that are commonly used for stress perfusion imaging. These agents are safe and provide an effective means ...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2008.12.003
更新日期:2009-05-01 00:00:00
abstract::Although electronic imaging was performed in the early 1950s in nuclear medicine, it was the introduction of computed tomography in 1972 that caused a revolution in medical imaging in that it marked the beginning of the inevitable transformation to digital imaging. This transformation is now more or less complete. Whi...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章,评审
doi:10.1053/j.semnuclmed.2018.11.010
更新日期:2019-03-01 00:00:00
abstract::The American Board of Nuclear Medicine gave its first certifying examination in 1972 to 1,096 candidates. It was established with the support of the Society of Nuclear Medicine amid considerable conflict involving the American Board of Radiology, the American Board of Internal Medicine, and the American Board of Patho...
journal_title:Seminars in nuclear medicine
pub_type: 历史文章,杂志文章
doi:10.1016/s0001-2998(96)80024-9
更新日期:1996-07-01 00:00:00
abstract::This review is directed at the clinically useful highlights of ultrasound and radionuclide testing in adults with coronary and valvular heart disease, intracardiac shunts, and hypertrophic and congestive cardiomyopathies. As a clinical toto, the radionuclide procedures are currently more useful than ultrasound examina...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(80)80031-6
更新日期:1980-01-01 00:00:00
abstract::Recently, the lung has received increasing attention as a metabolic organ. In this role, the lung modulates the composition of the arterial blood by several mechanisms: removing active substances from the plasma, releasing substances into the plasma, temporarily holding substances from circulation, and activating or i...
journal_title:Seminars in nuclear medicine
pub_type: 杂志文章
doi:10.1016/s0001-2998(86)80016-2
更新日期:1986-10-01 00:00:00