Rhenium-186 hydroxyethylidene diphosphonate for the treatment of painful osseous metastases.

abstract：:In the past, T3 suppression testing was often required to confirm the presence of autonomous thyroid function in patients with borderline clinical and laboratory findings suggestive of hyperthyroidism or in euthyroid patients with the stigmata of Graves' disease. Similarly, TSH stimulation testing was used to document...

journal_title：Seminars in nuclear medicine

authors： Hurley JR,Becker DV

更新日期：1981-04-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:The concept of brain death has gained importance in the past few decades to prevent futile attempts to sustain ventilation and blood circulation when the brain has lost all function and to procure beneficial tissues or life-saving organs for transplantation. However, differences remain among professional societies and...

journal_title：Seminars in nuclear medicine

authors： Sinha P,Conrad GR

更新日期：2012-01-01 00:00:00

abstract：:Postsurgical bile leaks can be associated with significant morbidity and even mortality, if not identified and treated at an early phase. Hepatobiliary iminodiacetic acid (HIDA) scan is an important test for detection of bile leaks in the postoperative abdomen. However, the lack of anatomical details on planar images ...

journal_title：Seminars in nuclear medicine

authors： Matesan M,Bermo M,Cruite I,Shih CH,Elojeimy S,Behnia F,Lewis D,Vesselle H

更新日期：2017-11-01 00:00:00

abstract：:Prospective delineation of viable from nonviable myocardium in patients with coronary artery disease in an important factor in deciding whether a patient should be revascularized or treated medically. Two common techniques--single-photon emission computed tomography (SPECT) and positron-emission computed tomography (P...

journal_title：Seminars in nuclear medicine

authors： Saha GB,MacIntyre WJ,Brunken RC,Go RT,Raja S,Wong CO,Chen EQ

更新日期：1996-10-01 00:00:00

abstract：:Recently, the lung has received increasing attention as a metabolic organ. In this role, the lung modulates the composition of the arterial blood by several mechanisms: removing active substances from the plasma, releasing substances into the plasma, temporarily holding substances from circulation, and activating or i...

journal_title：Seminars in nuclear medicine

authors： Touya JJ,Rahimian J,Corbus HF,Grubbs DE,Savala KM,Glass EC,Bennett LR

更新日期：1986-10-01 00:00:00

abstract：:The radionuclide (99m)Tc-MDP bone scan is one of the most commonly performed nuclear medicine studies and helps in the diagnosis of different pathologies relating to the musculoskeletal system. With its increasing utility in clinical practice, it becomes more important to be aware of various limitations of this imagin...

journal_title：Seminars in nuclear medicine

authors： Agrawal K,Marafi F,Gnanasegaran G,Van der Wall H,Fogelman I

更新日期：2015-09-01 00:00:00

abstract：:In the early 1970s, when Seminars in Nuclear Medicine started publication, little was known about the quality of reporting in biomedical journals. Senior scholars were invited to become scientific editors of journals based on their research credibility and stature. Their knowledge of journalology (publication science)...

journal_title：Seminars in nuclear medicine

authors： Wilson M,Moher D

更新日期：2019-03-01 00:00:00

abstract：:Radioimmunotherapy is a form of targeted radionuclide therapy that uses a monoclonal antibody to deliver localized radiation. It is most appropriate for treatment of multiple tumor sites that cannot be readily excised surgically or irradiated using external beam radiation or brachytherapy. At present, 2 products, Bexx...

journal_title：Seminars in nuclear medicine

authors： Goldsmith SJ

更新日期：2010-03-01 00:00:00

abstract：:Much efficacy is gained in clinical practice if a single agent can be used for both diagnosis and therapy, a practice termed theranostics. Metaiodobenzylguanidine (mIBG), a norepinephrine analogue with high sensitivity and specificity for neuroblastoma, is an exemplar of theranostics. The physiologic biodistribution o...

journal_title：Seminars in nuclear medicine

authors： Parisi MT,Eslamy H,Park JR,Shulkin BL,Yanik GA

更新日期：2016-05-01 00:00:00

abstract：:Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigr...

journal_title：Seminars in nuclear medicine

authors： Mandell GA,Alexander MA,Harcke HT

更新日期：1993-10-01 00:00:00

abstract：:Suspecting and diagnosing venous thrombosis and pulmonary embolism remain major clinical problems. For a variety of reasons, including the patient's pre-existing cardiac and pulmonary status and the release of humoral mediators, pulmonary emboli evoke varied responses in different patients. Symptoms and signs of pulmo...

journal_title：Seminars in nuclear medicine

authors： Palevsky HI

更新日期：1991-10-01 00:00:00

abstract：:Molecular imaging has revolutionized clinical oncology by imaging-specific facets of cancer biology. Through noninvasive measurements of tumor physiology, targeted radiotracers can serve as biomarkers for disease characterization, prognosis, response assessment, and predicting long-term response/survival. In turn, the...

journal_title：Seminars in nuclear medicine

authors： Gillman JA,Pantel AR,Mankoff DA,Edmonds CE

更新日期：2020-11-01 00:00:00

abstract：:In the 1980s, the (111)In-labeled somatostatin analog OctreoScan (Covidien, Hazelwood, MO) was developed for imaging of somatostatin receptor subtype 2 (sst(2)) overexpressing tumors. On the basis of this success, peptide receptor radionuclide therapy (PRRT) was developed using similar somatostatin analogs with differ...

journal_title：Seminars in nuclear medicine

authors： Pool SE,Krenning EP,Koning GA,van Eijck CH,Teunissen JJ,Kam B,Valkema R,Kwekkeboom DJ,de Jong M

更新日期：2010-05-01 00:00:00

abstract：:Tc-99m pyrophosphate is the grandfather of infarct avid agents. Its value is its clinical availability and ease of use. However, its shortcomings are the delay of 2 to 3 days for reliable interpretation in nonreperfused myocardial infarction (MI) and the overarching bone activity. Antimyosin provides exquisite specifi...

journal_title：Seminars in nuclear medicine

authors： Khaw BA

更新日期：1999-07-01 00:00:00

abstract：:The results of quantitative analysis of planar thallium-201 stress scintigraphy are superior to those of visual analysis. The increased sensitivity for detection of coronary artery disease is associated with maintenance of specificity. Consequently, we believe that quantitative analysis is the state-of-the-art for pla...

journal_title：Seminars in nuclear medicine

authors： Wackers FJ,Fetterman RC,Mattera JA,Clements JP

更新日期：1985-01-01 00:00:00

abstract：:According to SEER Cancer Statistics Review there are around 165,000 new prostate cancer cases estimated in 2018 accounting for 9.5% of all newly diagnosed cancers. Accurate staging of primary prostate cancer is important for therapy selection (local vs systemic). Recent developments in molecular imaging may significan...

journal_title：Seminars in nuclear medicine

authors： Pomykala KL,Farolfi A,Hadaschik B,Fendler WP,Herrmann K

更新日期：2019-07-01 00:00:00

abstract：:There seems little doubt that the ability to prepare antibodies with a unique specificity for surface tumor antigens will have a tremendous usefulness in the diagnostic and therapeutics of cancer. This usefulness will be wide-ranged when the antibodies are labeled with radioisotopes as tools for screening for primary ...

journal_title：Seminars in nuclear medicine

authors： Spar IL

更新日期：1976-10-01 00:00:00

abstract：:Regional cerebral blood flow (rCBF) findings and their application to cerebrovascular disease are reviewed. Although the coupling of cerebral blood flow and metabolism are best studied with positron emission tomography, single-photon emission computed tomography measurements of rCBF can contribute to patient managemen...

journal_title：Seminars in nuclear medicine

authors： Hellman RS,Tikofsky RS

更新日期：1990-10-01 00:00:00

abstract：:The remarkable progress in immunologic techniques in the development of monoclonal antibodies offers the potential for powerful new tools for the detection of cardiovascular disorders, such as acute myocardial necrosis and acute deep venous thrombosis, in an accurate, safe, and noninvasive manner. Historically the use...

journal_title：Seminars in nuclear medicine

authors： Manspeaker P,Weisman HF,Schaible TF

更新日期：1993-04-01 00:00:00

abstract：:The short range and high linear energy transfer of α-particles offer the potential for efficient tumor killing while sparing normal bystander cells. Hematologic malignancies are ideally suited to targeted α-particle therapy (TAT) due to easy accessibility of malignant cells in blood, bone marrow, lymph nodes, and sple...

journal_title：Seminars in nuclear medicine

authors： Jurcic JG

更新日期：2020-03-01 00:00:00

abstract：:In this work, we provide preliminary data and a review of the literature regarding normal structural and functional changes that occur in the aging uterus, ovary, testicle, and prostate gland. It is expected that such knowledge will help physicians to distinguish physiologic changes from pathologic changes at an early...

journal_title：Seminars in nuclear medicine

authors： Well D,Yang H,Houseni M,Iruvuri S,Alzeair S,Sansovini M,Wintering N,Alavi A,Torigian DA

更新日期：2007-05-01 00:00:00

abstract：:The basic principles of the use of radiation dosimetry in nuclear medicine are reviewed. The basic structure of the main mathematical equations are given and formal dosimetry systems are discussed. An extensive overview of the history and current status of anthropomorphic models (phantoms) is given. The sources and ma...

journal_title：Seminars in nuclear medicine

authors： Stabin M,Xu XG

更新日期：2014-05-01 00:00:00

abstract：:Bone scintigraphy of the hands and wrists represents an important adjunct imaging technique that complements plain film radiographic examination. The use of the three-phase bone scan provides clinical information not only regarding osseous uptake but the blood flow and extravascular distribution of the radiotracer as ...

journal_title：Seminars in nuclear medicine

authors： Vande Streek P,Carretta RF,Weiland FL,Shelton DK

更新日期：1998-01-01 00:00:00

abstract：:The use of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in prostate cancer depends on the phase of the disease along the natural history of this prevalent malignancy in men. Incidental high FDG uptake in the prostate gland, although rare, should prompt further investigation with at least a meas...

journal_title：Seminars in nuclear medicine

authors： Jadvar H

更新日期：2016-11-01 00:00:00

abstract：:Nuclear dacryocystography is simple, relatively harmless method of evaluating patients suspected of having abnormalities of the nasolacrimal drainage system. A group of normal saline containing approximately 100 muCi of 99mTc-pertechnetate is placed on the conjunctiva near the lateral canthus, and serial scintigrams a...

journal_title：Seminars in nuclear medicine

authors： Brown M,El Gammal TA,Luxenberg MN,Eubig C

更新日期：1981-10-01 00:00:00

abstract：:Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...

journal_title：Seminars in nuclear medicine

authors： Hofman MS,Hicks RJ

更新日期：2016-09-01 00:00:00

abstract：:Positron emission tomography (PET) of local cerebral glucose utilization is highly sensitive in detecting epileptogenic regions that correspond to electrographic localization in patients with epilepsy. In medically refractory temporal lobe epilepsy for which surgical resection of the epileptogenic zone is a therapeuti...

journal_title：Seminars in nuclear medicine

authors： Chugani HT

更新日期：1992-10-01 00:00:00

abstract：:Depending on the iodine supply of an area, the incidence of thyroid cancer ranges between 4 and 12/100,000 per year. To detect thyroid cancer in an early stage, the assessment of thyroid nodules includes ultrasonography, ultrasonography-guided fine-needle aspiration biopsy, and conventional scintigraphic methods using...

journal_title：Seminars in nuclear medicine

authors： Lind P,Kohlfürst S

更新日期：2006-07-01 00:00:00

abstract：:Bone metastases are associated with increased morbidity and poor prognosis in castration-resistant prostate cancer. Since 2010, 5 systemic therapies for metastatic castration-resistant prostate cancer have been approved by the US Food and Drug Administration based on an improvement in overall survival, offering altern...

journal_title：Seminars in nuclear medicine

authors： Abi-Ghanem AS,McGrath MA,Jacene HA

更新日期：2015-01-01 00:00:00