Evaluation of myocardial perfusion and function by single photon emission computed tomography.

abstract：:Radioimmunotherapy is a form of targeted radionuclide therapy that uses a monoclonal antibody to deliver localized radiation. It is most appropriate for treatment of multiple tumor sites that cannot be readily excised surgically or irradiated using external beam radiation or brachytherapy. At present, 2 products, Bexx...

journal_title：Seminars in nuclear medicine

authors： Goldsmith SJ

更新日期：2010-03-01 00:00:00

abstract：:The basic principles of the use of radiation dosimetry in nuclear medicine are reviewed. The basic structure of the main mathematical equations are given and formal dosimetry systems are discussed. An extensive overview of the history and current status of anthropomorphic models (phantoms) is given. The sources and ma...

journal_title：Seminars in nuclear medicine

authors： Stabin M,Xu XG

更新日期：2014-05-01 00:00:00

abstract：:In this work, we provide preliminary data and a review of the literature regarding normal structural and functional changes that occur in the aging uterus, ovary, testicle, and prostate gland. It is expected that such knowledge will help physicians to distinguish physiologic changes from pathologic changes at an early...

journal_title：Seminars in nuclear medicine

authors： Well D,Yang H,Houseni M,Iruvuri S,Alzeair S,Sansovini M,Wintering N,Alavi A,Torigian DA

更新日期：2007-05-01 00:00:00

abstract：:The objective of this work is to compare the characteristics of various techniques for functional renal imaging, with a focus on nuclear medicine and magnetic resonance imaging. Even with low spatial resolution and rather poor signal-to-noise ratio, classical nuclear medicine has the advantage of linearity and good se...

journal_title：Seminars in nuclear medicine

authors： Durand E,Chaumet-Riffaud P,Grenier N

更新日期：2011-01-01 00:00:00

abstract：:Due to the increasing life expectancy, the diagnosis of malignancy and treatment of elderly patients is becoming more common. Prostate cancer is particularly frequent in this setting. Many different approaches are now available, but some of them imply significant risks or collateral effects. In those patients an accur...

journal_title：Seminars in nuclear medicine

authors： Castellucci P,Nanni C,Ambrosini V

更新日期：2018-11-01 00:00:00

abstract：:Over the past several decades, PET has emerged as critical to accurate staging and restaging of lymphomas. Nonetheless, a number of critical issues regarding its optimal use remain. Whereas risk-adapted strategies appear to improve the outcome of patients with Hodgkin lymphoma, results are less convincing in non-Hodgk...

journal_title：Seminars in nuclear medicine

authors： Cheson BD

更新日期：2018-01-01 00:00:00

abstract：:The advantage of immunoscintigraphy over autologous leukocyte techniques in the imaging of infection is the simplicity of its use compared with techniques that require the isolation of autologous white blood cells. The advantage over 99mTc- or 111In-labeled nonspecific human immunoglobulin is the excellent target-to-b...

journal_title：Seminars in nuclear medicine

authors： Becker W,Goldenberg DM,Wolf F

更新日期：1994-04-01 00:00:00

abstract：:In the 1980s, the (111)In-labeled somatostatin analog OctreoScan (Covidien, Hazelwood, MO) was developed for imaging of somatostatin receptor subtype 2 (sst(2)) overexpressing tumors. On the basis of this success, peptide receptor radionuclide therapy (PRRT) was developed using similar somatostatin analogs with differ...

journal_title：Seminars in nuclear medicine

authors： Pool SE,Krenning EP,Koning GA,van Eijck CH,Teunissen JJ,Kam B,Valkema R,Kwekkeboom DJ,de Jong M

更新日期：2010-05-01 00:00:00

abstract：:Rhenium-186 (tin)hydroxyethylidene diphosphonate (HEDP) is a new radiopharmaceutical that localizes in skeletal metastases in patients with advanced cancer. A single intravenous administration of approximately 34 mCi (1,258 MBq) resulted in significant improvement in pain in 33 of 43 evaluable patients (77%) following...

journal_title：Seminars in nuclear medicine

authors： Maxon HR 3rd,Thomas SR,Hertzberg VS,Schroder LE,Englaro EE,Samaratunga R,Scher HI,Moulton JS,Deutsch EA,Deutsch KF

更新日期：1992-01-01 00:00:00

abstract：:Most of the components of the thrombotic and fibrinolytic systems have at some time been evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have been promising enough to emerge from investigational status to routine clinical use. New approaches are being explored, including improv...

journal_title：Seminars in nuclear medicine

authors： Knight LC

更新日期：1990-01-01 00:00:00

abstract：:Recent advances in the efficient production of high purity radioiodine (123I) and new efficient radiolabeling techniques have allowed the development of new classes of cardiovascular radiopharmaceuticals. These include 123I-labeled fatty acids to assess myocardial metabolism, 123I-metaiodobenzylguanidine (MIBG) for my...

journal_title：Seminars in nuclear medicine

authors： Kulkarni PV,Corbett JR

更新日期：1990-04-01 00:00:00

abstract：:Detection of acute myocardial infarction as an area of increased activity has intrigued investigators for some time. Initial attempts with 203Hg-chlormerodrin and 203Hg-fluorescein analogues were successful in man. More recently, however, successful imaging of the acute myocardial infarct has been achieved with severa...

journal_title：Seminars in nuclear medicine

authors： Holman BL,Davis MA,Hanson RN

更新日期：1977-01-01 00:00:00

abstract：:The concept of brain death has gained importance in the past few decades to prevent futile attempts to sustain ventilation and blood circulation when the brain has lost all function and to procure beneficial tissues or life-saving organs for transplantation. However, differences remain among professional societies and...

journal_title：Seminars in nuclear medicine

authors： Sinha P,Conrad GR

更新日期：2012-01-01 00:00:00

abstract：:In epilepsy, a detailed history, blood chemistry, routine electroencephalography, and brain MRI are important for the diagnosis of seizure type or epilepsy syndrome for the decision of appropriate drug treatment. Although antiepileptic drugs are mostly successful for controlling epileptic seizures, 20%-30% patients ar...

journal_title：Seminars in nuclear medicine

authors： Ergün EL,Saygi S,Yalnizoglu D,Oguz KK,Erbas B

更新日期：2016-07-01 00:00:00

abstract：:The definition of tumor involved volumes in patients with head and neck cancer poses great challenges with the increasing use of highly conformal radiotherapy techniques eg, volumetric modulated arc therapy and intensity modulated proton therapy. The risk of underdosing the tumor might increase unless great care is ta...

journal_title：Seminars in nuclear medicine

authors： Jensen K,Al-Farra G,Dejanovic D,Eriksen JG,Loft A,Hansen CR,Pameijer FA,Zukauskaite R,Grau C

更新日期：2021-01-01 00:00:00

abstract：:Much efficacy is gained in clinical practice if a single agent can be used for both diagnosis and therapy, a practice termed theranostics. Metaiodobenzylguanidine (mIBG), a norepinephrine analogue with high sensitivity and specificity for neuroblastoma, is an exemplar of theranostics. The physiologic biodistribution o...

journal_title：Seminars in nuclear medicine

authors： Parisi MT,Eslamy H,Park JR,Shulkin BL,Yanik GA

更新日期：2016-05-01 00:00:00

abstract：:The American Board of Nuclear Medicine gave its first certifying examination in 1972 to 1,096 candidates. It was established with the support of the Society of Nuclear Medicine amid considerable conflict involving the American Board of Radiology, the American Board of Internal Medicine, and the American Board of Patho...

journal_title：Seminars in nuclear medicine

authors： Ross JF

更新日期：1996-07-01 00:00:00

abstract：:In the early 1970s, when Seminars in Nuclear Medicine started publication, little was known about the quality of reporting in biomedical journals. Senior scholars were invited to become scientific editors of journals based on their research credibility and stature. Their knowledge of journalology (publication science)...

journal_title：Seminars in nuclear medicine

authors： Wilson M,Moher D

更新日期：2019-03-01 00:00:00

abstract：:The best option for the treatment of end-stage renal disease is kidney transplantation. Prompt diagnosis and management of early posttransplantation complications is of utmost importance for graft survival. Biochemical markers, allograft biopsies, and imaging modalities are used for the timely recognition and manageme...

journal_title：Seminars in nuclear medicine

authors： Aktaş A

更新日期：2014-03-01 00:00:00

abstract：:One of the major mechanisms of implementing the International Atomic Energy Agency's (IAEA) programs in nuclear medicine has been through coordinated research projects (CRPs). In recent years, the IAEA has initiated a new type of CRP, called Doctoral CRP, in an attempt to further improve the effectiveness of its progr...

journal_title：Seminars in nuclear medicine

authors： Padhy AK,Dondi M

更新日期：2008-03-01 00:00:00

abstract：:Prospective delineation of viable from nonviable myocardium in patients with coronary artery disease in an important factor in deciding whether a patient should be revascularized or treated medically. Two common techniques--single-photon emission computed tomography (SPECT) and positron-emission computed tomography (P...

journal_title：Seminars in nuclear medicine

authors： Saha GB,MacIntyre WJ,Brunken RC,Go RT,Raja S,Wong CO,Chen EQ

更新日期：1996-10-01 00:00:00

abstract：:99mTc-PYP myocardial scintigrams represent a means to detect and localize acute myocardial necrosis. These scintigrams are expected to be abnormal with acute myocardial infarcts of at least 3 grams in weight if serial imaging is utilized and proper attention to technique is provided. Any etiology of myocardial necrosi...

journal_title：Seminars in nuclear medicine

authors： Willerson JT,Parkey RW,Bonte FJ,Lewis SE,Corbett J,Buja LM

更新日期：1980-01-01 00:00:00

abstract：:Mammographic screening of women age 40 and older can reduce breast cancer deaths by at least 30% to 40%. However, not all cancers are detected by mammography. Although a new supplementary modality for screening could, in theory, fill in this detection gap, such utilization must be based on rigorous demonstration of it...

journal_title：Seminars in nuclear medicine

authors： Feig SA

更新日期：1999-01-01 00:00:00

abstract：:Prostate cancer remains an important and growing health problem. Advances in imaging of prostate cancer may help to achieve earlier and more accurate diagnosis and treatment. We review the various strategies using reporter genes for molecular imaging of prostate cancer. These approaches are emerging as valuable tools ...

journal_title：Seminars in nuclear medicine

authors： Singh A,Massoud TF,Deroose C,Gambhir SS

更新日期：2008-01-01 00:00:00

abstract：:Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration ...

journal_title：Seminars in nuclear medicine

authors： Hofman MS,Hicks RJ

更新日期：2016-09-01 00:00:00

abstract：:Up to 25% of the diabetic population is at risk for developing a pedal ulcer. These ulcers serve as a portal of entry for osteomyelitis and overlie more than 90% of diabetic pedal osteomyelitis cases. The diagnosis of osteomyelitis often is overlooked, and imaging studies are an essential part of the evaluation. The m...

journal_title：Seminars in nuclear medicine

authors： Palestro CJ,Love C

更新日期：2009-01-01 00:00:00

abstract：:According to SEER Cancer Statistics Review there are around 165,000 new prostate cancer cases estimated in 2018 accounting for 9.5% of all newly diagnosed cancers. Accurate staging of primary prostate cancer is important for therapy selection (local vs systemic). Recent developments in molecular imaging may significan...

journal_title：Seminars in nuclear medicine

authors： Pomykala KL,Farolfi A,Hadaschik B,Fendler WP,Herrmann K

更新日期：2019-07-01 00:00:00

abstract：:Radionuclide angiocardiography and myocardial perfusion imaging with exercise are valuable methods to assess patients undergoing percutaneous transluminal coronary angioplasty. Successful angioplasty results in improvement in ventricular systolic and diastolic function and regional perfusion. Complications of angiopla...

journal_title：Seminars in nuclear medicine

authors： DePuey EG

更新日期：1991-04-01 00:00:00

abstract：:Radiation and concurrent chemoradiation are essential in the treatment of head and neck cancers because they allow a potentially curative organ preservation approach in a manner that greatly affects quality of life. Greater doses of radiation to areas of gross disease have invariably led to greater loco-regional contr...

journal_title：Seminars in nuclear medicine

authors： Ahn PH,Garg MK

更新日期：2008-03-01 00:00:00

abstract：:In the past 20 years there have been great advances in our understanding of the molecular genetics of gastrointestinal tumors. In general, cancers develop and proliferate due to: driver mutations or related alterations in the genome resulting in overactivity of oncogenes, underactivity of tumor suppressor genes allowi...

journal_title：Seminars in nuclear medicine

authors： Wahl RL

更新日期：2020-09-01 00:00:00