Abstract:
:This study test the effects on autonomic nervous system (ANS) activity of two doses (0.25 mg/kg and 0.50 mg/kg) of dextroamphetamine in normal men. Skin conductance and heart rate were recorded during rest, tone presentation, and a reaction time task. Compared to placebo, dextroamphetamine increased both skin conductance and heart rate indices of arousal, slowed habituation, and reduced ANS responsivity selectively to more important vs. less important stimuli. The last result differs from previous findings on hyperactive and normal boys. The pattern of ANS effects closely resembles findings on drug-free schizophrenics, suggesting that it may be a matter for biologic changes occurring in amphetamine psychosis and spontaneous psychotic episodes.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Zahn TP,Rapoport JL,Thompson CLdoi
10.1016/0165-1781(81)90006-8subject
Has Abstractpub_date
1981-02-01 00:00:00pages
39-47issue
1eissn
0165-1781issn
1872-7123pii
0165-1781(81)90006-8journal_volume
4pub_type
临床试验,杂志文章abstract::Jumping to conclusions (JTC) is defined as a tendency to make decisions based on insufficient information. JTC has been reported in patients with psychosis, but the mechanisms of this cognitive bias remain unknown. The main aim of our study was to investigate the relationship between JTC and neuropsychological functio...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.01.035
更新日期:2019-03-01 00:00:00
abstract::We report the initial results of the first controlled double-blind trial of nimodipine, a calcium channel antagonist, in the acute and prophylactic treatment of patients with treatment-refractory affective dysregulation. Active drug nimodipine (A) was substituted for placebo (B) in 12 patients. Patients were studied i...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-1781(93)90066-p
更新日期:1993-12-01 00:00:00
abstract::This study examines the relationships between explicit and implicit self-esteem and self-referent memory biases in depression. We specifically tested the hypothesis that implicit self-esteem would influence depression-related memory biases via its association with explicit self-esteem. Self-esteem was assessed in pati...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.06.003
更新日期:2016-08-30 00:00:00
abstract::Traditional analyses and interpretation of controlled trials rely on measures of central tendency (e.g., mean findings for treatment versus control) to detect treatment effects. These trial designs therefore emphasize homogeneity of results, with variations within the experimental or control groups treated as error to...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.112520
更新日期:2020-01-01 00:00:00
abstract::Hypersensitivity to sensory stimulation is a prominent characteristic of both schizophrenia and mania. Neurophysiological recordings suggest a common deficit in a central neuronal sensory gating mechanism which regulates sensitivity to repeated auditory stimuli. Dopamine and norepinephrine are hypothesized to have maj...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(90)90099-q
更新日期:1990-03-01 00:00:00
abstract::The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to e...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.07.079
更新日期:2014-12-15 00:00:00
abstract::There is little evidence on the association between area-level social factors and schizophrenia in China. This study aimed to investigate the relationship between county-level social factors and schizophrenia in Chinese adults aged 18 years old and above. We obtained data from the Second China National Sample Survey o...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.057
更新日期:2019-01-01 00:00:00
abstract::Recent studies suggest a higher threshold number of self-injuries during the past year than the one proposed in the DSM-5 criteria for non-suicidal self-injury disorder (NSSID). Therefore, we aimed to test a validity of the frequency criterion in girls with conduct disorder (CD) based on psychopathology and the level ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.05.054
更新日期:2018-09-01 00:00:00
abstract::Twenty-one unmedicated, sequentially admitted psychiatric patients of either sex and four male healthy volunteers were given an intravenous injection of 2.5 mg morphine. Blood samples were drawn immediately before and at 30-minute intervals for 3 hours after the injection and assayed for cortisol. Morphine suppressed ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(85)90044-7
更新日期:1985-06-01 00:00:00
abstract::Absent lunula can progressively develop in a person who previously had a normal-sized lunula and can be associated with various systemic disorders. In this case-control study we hypothesised that absent lunula is associated with depression. The study comprised 332 depressive outpatients as well as 367 age- and sex-mat...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.08.011
更新日期:2013-01-30 00:00:00
abstract::The objectives of the present study were to describe the prescribing patterns for psychosocial therapies in routine clinical practice and to assess the impact of psychoeducation on symptoms and social autonomy of patients with schizophrenia. We used data from the nationwide French ESPASS observational cohort study inc...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.10.048
更新日期:2017-01-01 00:00:00
abstract::Several recent studies in animals and man indicate that corticosteroids may alter catecholaminergic activity in both the peripheral and central nervous systems. We administered 1 mg of the synthetic glucocorticoid, dexamethasone, to 12 drug-free healthy volunteers and measured plasma homovanillic acid (HVA) and 3-meth...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(85)90003-4
更新日期:1985-10-01 00:00:00
abstract::Increasing evidence implicates altered dopamine function in major affective illness. In the present study, growth hormone responses to the dopamine agonist apomorphine were not different for 14 male depressed patients and 16 healthy male volunteers. Baseline and post-apomorphine prolactin levels were lower for the dep...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90113-6
更新日期:1984-09-01 00:00:00
abstract::Trait anxiety, a personality dimension, has been characterized by functional consequences such as increased distractibility, attentional bias in favor of threat-related information and hyper-responsive amygdala. However, literature on the association between resting state brain functional connectivity, as studied usin...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.07.006
更新日期:2015-10-30 00:00:00
abstract::We conducted a retrospective chart-review study, examining predictors of the repetition of short-term self-harm (<1 month and <6 months) among the patients who were admitted to an emergency department in Japan following self-harm. A total of 405 patients were enrolled and were followed-up for a subsequent one year. Th...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.08.077
更新日期:2017-12-01 00:00:00
abstract::Klinefelter syndrome (47, XXY) is a sex chromosome aneuploidy associated with mild deficits in cognitive and language functions. Dysfunctions have also been reported in performance of tasks which examine executive functions. However, it is unclear whether the impaired performance is caused or accentuated by problems w...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.02.028
更新日期:2011-08-30 00:00:00
abstract::The PHQ-9 has been found to be reliable and valid, but with both a single and two-factor structure suggested in the literature. This measure has not yet been subject to psychometric investigation using Mokken scale analysis. Confirmatory Factor Analysis (CFA) and Mokken analysis were performed on retrospective data fr...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.12.048
更新日期:2019-01-01 00:00:00
abstract::We examined the prevalence of painful physical symptoms in patients with major depressive disorder (MDD), clinical correlations therewith, and associations between painful symptoms and depression severity, quality of life, and suicidality, in a clinical sample in Korea. A total of 414 psychiatric outpatients at least ...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2011.01.009
更新日期:2011-10-30 00:00:00
abstract::Voxel-based morphometry (VBM) is an objective whole-brain technique for characterizing regional cerebral volume and tissue concentration differences in structural magnetic resonance images. In the current study, we used VBM to examine possible cerebral gray matter abnormalities in patients with posttraumatic stress di...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2005.09.006
更新日期:2006-01-30 00:00:00
abstract::This study was designed to assess cognitive functioning in a clinical sample of adolescents with heterogeneous psychiatric diagnoses, with a specific focus on patients at clinical high risk (CHR) for psychosis. The sample comprised 22 patients identified at CHR for psychosis, 67 psychotic and 187 non-psychotic, non-CH...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.04.011
更新日期:2010-09-30 00:00:00
abstract::Recent magnetic resonance imaging (MRI) studies using diffusion tensor imaging (DTI) have suggested reduced fractional anisotropy (FA) in the white matter (WM) of the brain in patients with schizophrenia. We tried to examine whether such reduction in FA exists and whether such changes in FA progress in an age-dependen...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2006.09.004
更新日期:2007-02-28 00:00:00
abstract::Orexins have played a role in reward-seeking and addiction-related behavior. There are few reports in the literature on serum levels of orexins in patients with heroin use disorder (HUD) undergoing methadone maintenance treatment (MMT). The aim of this study was to investigate the serum levels of orexin A in HUD patie...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.010
更新日期:2018-06-01 00:00:00
abstract::The current study aimed to explore Israelis' state anxiety due to a Syrian-Israeli incident that occurred on February 10, 2018, when an Israeli F-16 fighter jet was shot down by Syrian air defense forces. In line with the "looming vulnerability" model which emphasizes the importance of the dynamic nature of psychologi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.10.072
更新日期:2018-12-01 00:00:00
abstract::The mineralocorticoid receptor (Nr3c2) has received increased attention as an important stress-related gene. Here, we sought to uncover candidate genes regulating the expression of Nr3c2. Using a genetical genomics approach, we identified a significant trans-regulated expression quantitative trait locus (eQTL) at Chro...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112760
更新日期:2020-01-07 00:00:00
abstract::A variable number of tandem repeats (VNTR) in the second intron of the serotonin transporter gene (STin2) has been studied in association with the susceptibility to affective disorders. Recently, it was reported that selective serotonin reuptake inhibitors were more effective in patients with major depressive disorder...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(02)00141-5
更新日期:2002-08-30 00:00:00
abstract::This descriptive study of 55 outpatients with unipolar major depression compared placebo responders (n = 21) and placebo nonresponders (n = 34) with respect to demographic, diagnostic, history of illness and symptomatic features of the current episode of depression. Placebo responders were significantly more likely to...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(86)90109-5
更新日期:1986-07-01 00:00:00
abstract::Childhood maltreatment history is a prevalent risk factor for substance use disorder and has lifelong adverse consequences on psychiatric wellbeing. The role of personality variations in determining childhood maltreatment-associated outcomes is poorly understood. This study sought to test neuroticism and agreeableness...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.07.010
更新日期:2018-10-01 00:00:00
abstract::The antipsychotic effects of dopamine D2 receptor antagonists (neuroleptics) and the psychotomimetic effects of dopamine agonists suggest that a defect of the D2 receptor gene might be a factor in the etiology of schizophrenia. Fifteen families that contained several members suffering from schizophrenia were tested fo...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(94)90111-2
更新日期:1994-08-01 00:00:00
abstract:UNLABELLED:Panic attacks occurring outside of Panic Disorder are not well-understood despite their inclusion as a diagnostic specifier in the Diagnostic and Statistical Manual for Mental Disorders (DSM-5). This study compares panic attacks in the context of Panic Disorder compared to social anxiety in terms of their sy...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.11.048
更新日期:2016-01-30 00:00:00
abstract::The impact of a single nucleotide polymorphism (SNP) in the CD24 gene on the risk and progression of multiple sclerosis (MS) was investigated in the Iranian population. Our data revealed that the susceptibility and the progression of MS in individuals with the CD24V/V genotype were greater than in those with the CD24A...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.01.002
更新日期:2009-12-30 00:00:00