Abstract：
:Twenty-one unmedicated, sequentially admitted psychiatric patients of either sex and four male healthy volunteers were given an intravenous injection of 2.5 mg morphine. Blood samples were drawn immediately before and at 30-minute intervals for 3 hours after the injection and assayed for cortisol. Morphine suppressed cortisol secretion. Early resumption of cortisol secretion (escape) was more frequent in patients with a diagnosis of major depressive disorder and with abnormal dexamethasone suppression test results. The sensitivity of this infusion paradigm for the diagnosis of major depressive disorder was 40%, and the specificity was 82%. The implications of these findings for the pathophysiology of depression are discussed.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Zis AP,Haskett RF,Albala AA,Carroll BJ,Lohr NEdoi
10.1016/0165-1781(85)90044-7subject
Has Abstractpub_date
1985-06-01 00:00:00pages
91-5issue
2eissn
0165-1781issn
1872-7123pii
0165-1781(85)90044-7journal_volume
15pub_type
杂志文章abstract：:Ictal heart rate (HR) and postictal suppression in ictal EEG are believed to be predictive of the therapeutic efficacy of eletroconvulsive therapy (ECT) for depression. However, regarding ictal peak HR, previous studies investigated ictal HR on only one or two occasions during the course of ECT. We prospectively exami...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.05.007
更新日期：2011-02-28 00:00:00
abstract：:The main aim of this study was to investigate serum levels of adiponectin in adult patients with attention deficit hyperactivity disorder (ADHD). The second objective was to examine the effects of rare missense mutations in T-cadherin, an adiponectin receptor encoded by the ADHD candidate gene CDH13, on serum adiponec...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.01.025
更新日期：2014-04-30 00:00:00
abstract：:The legal status of service users admitted to psychiatric wards is not synonymous with the level of coercion that they can perceive during the admission. This study aimed to identify and describe the proportion of individuals who were admitted voluntarily but experienced levels of perceived coercion comparable to thos...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.10.016
更新日期：2014-01-30 00:00:00
abstract：:We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and th...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.02.012
更新日期：2008-10-30 00:00:00
abstract：:We investigated a combination of three classification algorithms, namely the modified maximum uncertainty linear discriminant analysis (mMLDA), the centroid method, and the average linkage, with three types of features extracted from three-dimensional T1-weighted magnetic resonance (MR) brain images, specifically MR i...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2015.03.004
更新日期：2015-06-30 00:00:00
abstract：:Disruptive behavior disorders (DBD) are among the most commonly diagnosed mental disorders in children and adolescents. Some important characteristics of DBD vary based on the presence or absence of comorbid attention-deficit/hyperactivity disorder (ADHD), which may affect the understanding of and treatment decision-m...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2012.01.005
更新日期：2012-06-30 00:00:00
abstract：:Posttraumatic stress disorder (PTSD) is increasingly recognized as a relatively common condition that is associated with poor health, including obesity. With a sizable proportion of the population approaching older adulthood, it is important to understand PTSD-health associations in the context of age. Participants we...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.07.044
更新日期：2015-10-30 00:00:00
abstract：:Recent work has suggested that anxiety restricts working memory capacity, which may underlie a wide range of cognitive symptoms in anxiety. However, previous literature on the anxiety-visual working memory association yielded mixed results, with some studies demonstrating an anxiety-related increase in visual working ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.10.018
更新日期：2018-12-01 00:00:00
abstract：:We examined the impact of a mental health awareness campaign on public attitudes. The campaign was embedded in the project psychenet - Hamburg Network for Mental Health. Beliefs and attitudes were examined before and after specific awareness measures in Hamburg (intervention region) and Munich (control region). Analys...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.01.029
更新日期：2016-03-30 00:00:00
abstract：:An epidemiological survey on anorexia nervosa was performed in Japanese hospitals in 1985 and 1992 using a questionnaire. The reported number of patients with anorexia nervosa was 2391 from 732 institutions. From these data, the total number of anorexia nervosa patients treated in 1985 in Japanese hospitals was estima...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(96)02988-5
更新日期：1996-04-16 00:00:00
abstract：:First-episode psychosis typically emerges during late adolescence or young adulthood, interrupting achievement of crucial educational, occupational, and social milestones. Recovery-oriented approaches to treatment may be particularly applicable to this critical phase of the illness, but more research is needed on the ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.05.039
更新日期：2011-10-30 00:00:00
abstract：BACKGROUND:High suicide attempt (SA) rates have been reported in first-episode psychosis (FEP) patients, particularly during the first year after the illness onset. Despite previous studies establishing several risk factors for suicidal behaviour in FEP, premorbid personality and social cognition have not been sufficie...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.05.050
更新日期：2017-10-01 00:00:00
abstract：:The symptom scores on the Schedule for Affective Disorders and Schizophrenia (SADS) of 21 unipolar and 12 bipolar depressive patients diagnosed with Research Diagnostic Criteria (RDC) were correlated with the monoamine metabolites homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol (MHPG), and 5-hydroxyindoleacet...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(80)90038-4
更新日期：1980-10-01 00:00:00
abstract：OBJECTIVE:Paliperidone, a second-generation antipsychotic, has been found to have minimal hepatotoxicity in patients with schizophrenia. However, long-term hepatic outcome in patients with schizophrenia and viral hepatitis remains unclear. METHODS:Data obtained from the Taiwan National Health Insurance Research Databa...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112597
更新日期：2019-11-01 00:00:00
abstract：:Past studies suggest that phenylthiocarbamide (PTC) taste status is related to vulnerability to depression, such that those sensitive to PTC are more vulnerable. We questioned this, reasoning that those insensitive to PTC may be more vulnerable (because they may have lower hedonic tone and higher risk for alcohol abus...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2003.12.020
更新日期：2004-04-15 00:00:00
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journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/s0165-1781(03)00063-5
更新日期：2003-05-01 00:00:00
abstract：:It has been suggested that reversal learning deficits might be an endophenotype of OCD. To investigate this hypothesis, we administered a probabilistic reversal learning task (ProbRev) to OCD patients, their unaffected first-degree relatives, and healthy controls. Although the relatives had a performance in between OC...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.03.001
更新日期：2017-06-01 00:00:00
abstract：:The aim of this study was to gain a better understanding of schizophrenia patients' strategic use of learning time allocation during encoding, and determine whether they are able to use their monitoring and previous performances to adapt their learning behavior efficiently. Schizophrenia is considered to be a patholog...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.07.036
更新日期：2012-01-30 00:00:00
abstract：:Firefighters represent a unique, vulnerable population at high risk for alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) symptomatology due to the high rates of occupational exposure to traumatic events. To inform specialized alcohol use interventions for firefighters, it is important to understand ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112633
更新日期：2019-12-01 00:00:00
abstract：:Genetic and environmental architecture of psychotic and obsessive symptoms are not completely elucidated. This study estimated for these symptoms (i) the genetic and environmental components, (ii) the within-individual association, and (iii) the extent to which this association originates from common genetic and envir...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.12.002
更新日期：2011-07-30 00:00:00
abstract：:The PHQ-9 has been found to be reliable and valid, but with both a single and two-factor structure suggested in the literature. This measure has not yet been subject to psychometric investigation using Mokken scale analysis. Confirmatory Factor Analysis (CFA) and Mokken analysis were performed on retrospective data fr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.12.048
更新日期：2019-01-01 00:00:00
abstract：:The primary goal of this study was to examine the biochemical abnormalities of late-life major depression by using 3-tesla (3-T) proton magnetic resonance spectroscopy ((1)H-MRS). The antidepressant effects on the biochemical abnormalities were investigated as well. Study participants were 27 elderly patients with maj...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2009.01.003
更新日期：2009-06-30 00:00:00
abstract：:Individuals who differ markedly by sleep chronotype, i.e., morning-type or evening-type also differ on a number of psychological, behavioral, and biological variables. Among several other psychological functions, dissociation may also lead to disruption and alteration of consciousness, which may facilitate dream-like ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.06.059
更新日期：2017-10-01 00:00:00
abstract：:The astonishing 20 fold growth of the yearly published psychiatric research literature over the past four decades has been paralleled and facilitated by the internet application of electronic publishing. This personal history highlights the decade by decade 1978-2018 augmentation and erosion of this interelationship f...
journal_title：Psychiatry research
pub_type： 历史文章,杂志文章
doi：10.1016/j.psychres.2019.01.071
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:This study aims to establish if adult patients with major depressive disorder (MDD) and childhood Attention Deficit/Hyperactivity disorder (ADHD) symptoms would be more frequently within the bipolar spectrum than depressed patients without childhood ADHD. METHODS:This study was carried out in outpatients re...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.12.055
更新日期：2017-03-01 00:00:00
abstract：:The aim of this study was to investigate the impact of lifetime posttraumatic stress disorder (PTSD), dissociation and a history of childhood trauma on quality of life (QoL) among men with alcohol dependency. A consecutive series of alcohol-dependent men (N=156) admitted to an inpatient treatment unit were screened us...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.07.004
更新日期：2011-03-30 00:00:00
abstract：:Affiliated stigma often refers to internalized stigma among family members of stigmatized individuals. This study aimed to investigate the relationship between affiliate stigma and quality of life (QOL) among primary caregivers of individuals with mental illness undergoing treatment at the Institute of Mental Health, ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.044
更新日期：2018-07-01 00:00:00
abstract：:The centrally active muscarinic agonist RS-86 elicited a dose-dependent anergic-anhedonic syndrome in a double-blind dose-response study in one healthy volunteer. At 4 and 5 mg, RS-86 induced escape from cortisol suppression by dexamethasone parallel to an increase in prolactin. The time course, as well as the absence...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/0165-1781(88)90103-5
更新日期：1988-09-01 00:00:00
abstract：:The association of seven GDNF tag SNPs with depression, heroin dependence (HD) and schizophrenia was evaluated in Chinese. An increased risk of HD and depression was associated with rs2910709 T/T genotype and rs884344 C allele, respectively, suggesting GDNF is a novel susceptibility gene for depression and HD. ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.08.025
更新日期：2013-12-30 00:00:00
abstract：:Concentrations of plasma norepinephrine (NE) and plasma-3-methoxy-4-hydroxyphenylglycol (MHPG), blood pressure, and heart rate were measured on 2 days in 25 depressed patients and 25 controls. Comparisons were made between patients and controls, and also between days for both groups, to determine the short-term stabil...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(86)90093-4
更新日期：1986-09-01 00:00:00
