PTSD and obesity in younger and older veterans: Results from the mind your heart study.

Abstract:

:Posttraumatic stress disorder (PTSD) is increasingly recognized as a relatively common condition that is associated with poor health, including obesity. With a sizable proportion of the population approaching older adulthood, it is important to understand PTSD-health associations in the context of age. Participants were recruited from two Veterans Administration medical centers and included 380 patients age 60 and over and 365 under age 60. PTSD diagnosis was determined by the Clinician Administered PTSD Scale. BMI was trichotomized into normal/under (≤24.9), overweight (25.0-29.9), and obese (≥30.0). Models were run in the total sample, as well as stratified by age group, and adjusted for demographics, depression, antipsychotic medication use, and physical activity. Current PTSD was associated with greater likelihood of overweight and obesity in the total sample, and lifetime PTSD was associated with significantly increased odds of obesity. In the stratified models, current and lifetime PTSD were associated with increased likelihood of overweight and obesity in the older group only. Results suggest that PTSD is associated with risk for overweight and obesity, an effect that may be particularly strong in older adults. These findings support the importance of examining PTSD and potential health correlates across the life course.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Smith BN,Tyzik AL,Neylan TC,Cohen BE

doi

10.1016/j.psychres.2015.07.044

subject

Has Abstract

pub_date

2015-10-30 00:00:00

pages

895-900

issue

3

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(15)00501-6

journal_volume

229

pub_type

杂志文章
  • Platelet serotonin and serum cholesterol concentrations in suicidal and non-suicidal male patients with a first episode of psychosis.

    abstract::Suicidal behavior is a major health risk in psychiatric disorders, especially in schizophrenia, wherein up to 10% patients will commit suicide. However, the neurobiology of suicide is still unclear. Suicidality has been related to decreased central serotonergic (5-hydroxytryptamine, 5-HT) function and reduced choleste...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2006.08.012

    authors: Marcinko D,Pivac N,Martinac M,Jakovljević M,Mihaljević-Peles A,Muck-Seler D

    更新日期:2007-02-28 00:00:00

  • Negative affect predicts social functioning across schizophrenia and bipolar disorder: Findings from an integrated data analysis.

    abstract::Most people with a serious mental illness experience significant functional impairment despite ongoing pharmacological treatment. Thus, in order to improve outcomes, a better understanding of functional predictors is needed. This study examined negative affect, a construct comprised of negative emotional experience, a...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.06.031

    authors: Grove TB,Tso IF,Chun J,Mueller SA,Taylor SF,Ellingrod VL,McInnis MG,Deldin PJ

    更新日期:2016-09-30 00:00:00

  • Specificity of depression following an acute coronary syndrome to an adverse outcome extends over five years.

    abstract::Many studies have demonstrated that depression is associated with a worse cardiovascular outcome and increased risk of death in those experiencing an acute coronary syndrome (ACS). Recent studies have suggested, however, that any association is strongly influenced by the timing of the depression, with post-ACS depress...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2010.07.015

    authors: Parker G,Hyett M,Walsh W,Owen C,Brotchie H,Hadzi-Pavlovic D

    更新日期:2011-02-28 00:00:00

  • White matter abnormalities associated with disruptive behavior disorder in adolescents with and without attention-deficit/hyperactivity disorder.

    abstract::Disruptive behavior disorders (DBD) are among the most commonly diagnosed mental disorders in children and adolescents. Some important characteristics of DBD vary based on the presence or absence of comorbid attention-deficit/hyperactivity disorder (ADHD), which may affect the understanding of and treatment decision-m...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2012.01.005

    authors: Wang Y,Horst KK,Kronenberger WG,Hummer TA,Mosier KM,Kalnin AJ,Dunn DW,Mathews VP

    更新日期:2012-06-30 00:00:00

  • Experimentally induced aggressiveness in heroin-dependent patients treated with buprenorphine: comparison of patients receiving methadone and healthy subjects.

    abstract::Objective measures of experimentally induced aggressiveness were evaluated in heroin-dependent patients (HDP), 15 receiving buprenorphine (BUP) and 15 receiving methadone (METH) treatment. HDP were randomly assigned to BUP and METH groups. Fifteen healthy subjects (CONT) were included in the study as controls. During ...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2006.02.013

    authors: Gerra G,Zaimovic A,Raggi MA,Moi G,Branchi B,Moroni M,Brambilla F

    更新日期:2007-01-15 00:00:00

  • Genotype-phenotype relationship in female carriers of the premutation and full mutation of FMR-1.

    abstract::The present French-German cooperative study focuses on the genotype-phenotype relationship of mutations of the FMR-1 gene and psychiatric conditions in mothers with a full mutation in the FMR-1 gene of fra-X children (n=13), mothers with a premutation in the FMR-1 gene of fra-X children (n=61), as well as premutated s...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(98)00055-9

    authors: Franke P,Leboyer M,Gänsicke M,Weiffenbach O,Biancalana V,Cornillet-Lefebre P,Croquette MF,Froster U,Schwab SG,Poustka F,Hautzinger M,Maier W

    更新日期:1998-08-17 00:00:00

  • Olfactory identification deficits and associated response inhibition in obsessive-compulsive disorder: on the scent of the orbitofronto-striatal model.

    abstract::Olfactory identification ability implicates the integrity of the orbitofrontal cortex (OFC). The fronto-striatal circuits including the OFC have been involved in the neuropathology of Obsessive Compulsive Disorder (OCD). However, only a few studies have examined olfactory function in patients with OCD. The Brief Smell...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2013.05.032

    authors: Bersani G,Quartini A,Ratti F,Pagliuca G,Gallo A

    更新日期:2013-11-30 00:00:00

  • Proton magnetic resonance spectroscopy of late-life major depressive disorder.

    abstract::The primary goal of this study was to examine the biochemical abnormalities of late-life major depression by using 3-tesla (3-T) proton magnetic resonance spectroscopy ((1)H-MRS). The antidepressant effects on the biochemical abnormalities were investigated as well. Study participants were 27 elderly patients with maj...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2009.01.003

    authors: Chen CS,Chiang IC,Li CW,Lin WC,Lu CY,Hsieh TJ,Liu GC,Lin HF,Kuo YT

    更新日期:2009-06-30 00:00:00

  • Sensory physiology and catecholamines in schizophrenia and mania.

    abstract::Hypersensitivity to sensory stimulation is a prominent characteristic of both schizophrenia and mania. Neurophysiological recordings suggest a common deficit in a central neuronal sensory gating mechanism which regulates sensitivity to repeated auditory stimuli. Dopamine and norepinephrine are hypothesized to have maj...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(90)90099-q

    authors: Adler LE,Gerhardt GA,Franks R,Baker N,Nagamoto H,Drebing C,Freedman R

    更新日期:1990-03-01 00:00:00

  • Medial frontal gyrus alterations in schizophrenia: relationship with duration of illness and executive dysfunction.

    abstract::Executive functioning is consistently impaired in schizophrenia, and it has been associated with reduced gray matter volume in prefrontal areas. Abnormalities in prefrontal brain regions have also been related to the illness duration. The aim of the study was to investigate the effect of executive functioning decline ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2014.10.017

    authors: Frascarelli M,Tognin S,Mirigliani A,Parente F,Buzzanca A,Torti MC,Tinelli E,Caramia F,Di Fabio F,Biondi M,Fusar-Poli P

    更新日期:2015-02-28 00:00:00

  • Dependency and suicidality in addictive disorders.

    abstract::Excessive interpersonal dependency has been described in depression and addictive disorders. Moreover, excessive dependency and suicidality are linked in psychiatric subjects, but their relationships have not been studied in specific addictions. Separate samples of female anorectic patients (n=150), female bulimic pat...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2004.06.022

    authors: Loas G,Guilbaud O,Perez-Diaz F,Verrier A,Stephan P,Lang F,Bizouard P,Venisse JL,Corcos M,Flament MF,Jeammet P,Réseau Inserm no. 494013.

    更新日期:2005-11-15 00:00:00

  • Predicting dementia development in Parkinson's disease using Bayesian network classifiers.

    abstract::Parkinson's disease (PD) has broadly been associated with mild cognitive impairment (PDMCI) and dementia (PDD). Researchers have studied surrogate, neuroanatomic biomarkers provided by magnetic resonance imaging (MRI) that may help in the early diagnosis of this condition. In this article, four classification models (...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2012.06.001

    authors: Morales DA,Vives-Gilabert Y,Gómez-Ansón B,Bengoetxea E,Larrañaga P,Bielza C,Pagonabarraga J,Kulisevsky J,Corcuera-Solano I,Delfino M

    更新日期:2013-08-30 00:00:00

  • Between- and within-scanner variability in the CaliBrain study n-back cognitive task.

    abstract::Psychiatric neuroimaging techniques are likely to improve understanding of the brain in health and disease, but studies tend to be small, based in one imaging centre and of unclear generalisability. Multicentre studies have great appeal but face problems if functional magnetic resonance imaging (fMRI) data from differ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2010.08.010

    authors: Gradin V,Gountouna VE,Waiter G,Ahearn TS,Brennan D,Condon B,Marshall I,McGonigle DJ,Murray AD,Whalley H,Cavanagh J,Hadley D,Lymer K,McIntosh A,Moorhead TW,Job D,Wardlaw J,Lawrie SM,Steele JD

    更新日期:2010-11-30 00:00:00

  • Cerebral metabolic pattern in obsessive-compulsive disorder: altered intercorrelations between regional rates of glucose utilization.

    abstract::Correlations between normalized regional cerebral metabolic rates for glucose, determined by positron emission tomography with 18F-2-fluoro-2-deoxy-D-glucose, were used to investigate functional associations between pairs of brain regions in 18 adult patients with primary obsessive-compulsive disorder (OCD) of childho...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0925-4927(91)90014-h

    authors: Horwitz B,Swedo SE,Grady CL,Pietrini P,Schapiro MB,Rapoport JL,Rapoport SI

    更新日期:1991-12-01 00:00:00

  • Significant association between DRD3 gene body methylation and schizophrenia.

    abstract::The current study was the first one to reveal the contribution of DRD3 methylation to the risk of different (SCZ) subtypes. This study comprised a total of 30 paranoid (15 males and 15 females) and 29 undifferentiated (15 males and 14 females) SCZ patients and 26 age- and gender-matched controls. Our results showed a ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.08.032

    authors: Dai D,Cheng J,Zhou K,Lv Y,Zhuang Q,Zheng R,Zhang K,Jiang D,Gao S,Duan S

    更新日期:2014-12-30 00:00:00

  • History of parenting instability and lifetime suicidal behavior in people who inject drugs.

    abstract::Despite high rates of suicide in people who inject drugs, little is known about the risk factors for suicide related to childhood and family history in this population. We aimed to explore the relationship between the history of out-of-home care (OHC) and lifetime suicide attempts among people who inject opioids. Part...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2019.112493

    authors: Tabi K,Choi F,Mithani Z,Nikoo M,Jang K,Krausz M

    更新日期:2019-10-01 00:00:00

  • Tardive dyskinesia in schizophrenic patients: correlation with negative symptoms.

    abstract::The relationship between severity of tardive dyskinesia (TD) and the prominence of negative symptoms was assessed in 25 right-handed, medicated schizophrenic patients. TD was quantified using ultrasound detectors and frequency measurement techniques as well as with observer rating scales. Electromechanical studies rev...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(89)90042-5

    authors: Bartzokis G,Hill MA,Altshuler L,Cummings JL,Wirshing W,May PR

    更新日期:1989-05-01 00:00:00

  • Impact of childhood exposure to psychological trauma on the risk of psychiatric disorders and somatic discomfort: single vs. multiple types of psychological trauma.

    abstract::We examined whether childhood exposure to multiple types of potentially traumatic events (PTEs) relative to a single type of PTE is associated with a higher prevalence of psychiatric disorders and greater somatic discomfort in Korean adults. The Composite International Diagnostic Interview 2.1 (K-CIDI 2.1) was adminis...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.06.009

    authors: Park S,Hong JP,Bae JN,Cho SJ,Lee DW,Lee JY,Chang SM,Jeon HJ,Hahm BJ,Lee YM,Seong S,Cho MJ

    更新日期:2014-11-30 00:00:00

  • Association of lifestyle-related factors and psychological factors on quality of life in people with schizophrenia.

    abstract::In people with schizophrenia several factors are associated with poor quality of life (QoL), namely, lifestyle-related factors and psychological factors. However, there has been little research on the impact of these factors on QoL. Therefore, the relation between lifestyle-related factors, psychological factors, and ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.06.022

    authors: Costa R,Bastos T,Probst M,Seabra A,Abreu S,Vilhena E,Rosenbaum S,Ward PB,Corredeira R

    更新日期:2018-09-01 00:00:00

  • An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population.

    abstract::Major depression (MD) is a common psychiatric disorder and one of its most serious symptoms is suicidal ideation. Six polymorphisms in four genes related to the serotonin system, including the HTTLPR and HTTVNTR in the SLC6A4 gene, rs6295 in the HTR1A gene, rs11568817 and rs130058 in the HTR1B gene, and rs6313 in the ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2008.12.006

    authors: Wang S,Zhang K,Xu Y,Sun N,Shen Y,Xu Q

    更新日期:2009-12-30 00:00:00

  • Effect of moderate weight loss on prolactin secretion in normal female volunteers.

    abstract::Sleep-related prolactin secretion and prolactin responses to the infusion of low doses of the dopamine antagonist, metoclopramide, and thyrotropin-releasing hormone were measured in 11 female volunteers before and after undertaking a diet in which they lost a mean of 3.1 kg in weight in 3 weeks. No effect of weight lo...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(89)90030-9

    authors: Anderson IM,Crook WS,Gartside SE,Parry-Billings M,Newsholme EA,Cowen PJ

    更新日期:1989-08-01 00:00:00

  • Increased amygdala activation during automatic processing of facial emotion in schizophrenia.

    abstract::Schizophrenia patients show abnormalities in the processing of facial emotion. The amygdala is a central part of a brain network that is involved in the perception of facial emotions. Previous functional neuroimaging studies on the perception of facial emotion in schizophrenia have focused almost exclusively on contro...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2010.03.005

    authors: Rauch AV,Reker M,Ohrmann P,Pedersen A,Bauer J,Dannlowski U,Harding L,Koelkebeck K,Konrad C,Kugel H,Arolt V,Heindel W,Suslow T

    更新日期:2010-06-30 00:00:00

  • Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa.

    abstract::Individuals with anorexia nervosa (AN) and bulimia nervosa (BN) have alterations of measures of serotonin (5-HT) and dopamine (DA) function, which persist after long-term recovery and are associated with elevated harm avoidance (HA), a measure of anxiety and behavioral inhibition. Based on theories that 5-HT is an ave...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2012.06.010

    authors: Bailer UF,Frank GK,Price JC,Meltzer CC,Becker C,Mathis CA,Wagner A,Barbarich-Marsteller NC,Bloss CS,Putnam K,Schork NJ,Gamst A,Kaye WH

    更新日期:2013-02-28 00:00:00

  • Anxiety mediates the association between cannabis use and attenuated positive psychotic symptoms.

    abstract::Cannabis use has been associated with a continuum of psychotic experiences. However, it is unclear whether mood and anxiety symptoms account for increases in attenuated positive psychotic symptoms (APPS) among cannabis users. We predicted that depression and anxiety symptoms would mediate the relation between cannabis...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.03.040

    authors: Reeves LE,Anglin DM,Heimberg RG,Gibson LE,Fineberg AM,Maxwell SD,Kerns CM,Ellman LM

    更新日期:2014-08-15 00:00:00

  • Are predictors of future suicide attempts and the transition from suicidal ideation to suicide attempts shared or distinct: a 12-month prospective study among patients with depressive disorders.

    abstract::Our study aimed to examine the interplay between clinical and social predictors of future suicide attempt and the transition from suicidal ideation to suicide attempt in depressive disorders. Sixty-six Malaysian inpatients with a depressive disorder were assessed at index admission and within 1 year for suicide attemp...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.08.055

    authors: Chan LF,Shamsul AS,Maniam T

    更新日期:2014-12-30 00:00:00

  • Psychotic and nonpsychotic depressions: II. Platelet MAO activity, plasma catecholamines, cortisol, and specific symptoms.

    abstract::Preliminary data are presented on levels of plasma cortisol, dopamine (DA), epinephrine (EPI), and norepinephrine (NE) before and after dexamethasone in 22 depressed patients (of whom 4 were psychotic). Platelet monoamine oxidase (MAO) activity, determined in 19 of the depressed patients, was significantly higher in t...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(87)90007-2

    authors: Schatzberg AF,Rothschild AJ,Langlais PJ,Lerbinger JE,Schildkraut JJ,Cole JO

    更新日期:1987-02-01 00:00:00

  • Negative correlation between CSF lactate levels and MoCA scores in male Chinese subjects.

    abstract::Lactate is a product of glycolysis by astrocytes and can be generated as a primary metabolic energy source by neurons. Lactate plays multifunctional role in human brain energy metabolism and cognitive function. However, no direct evidence demonstrated the link between lactate and cognition in normal condition. In the ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.05.017

    authors: Wang H,Tan X,Xu J,Li H,Wang M,Chen S,Yang X,Liu Y,Wang F

    更新日期:2017-09-01 00:00:00

  • Light to moderate alcohol use is associated with increased cortical gray matter in middle-aged men: a voxel-based morphometric study.

    abstract::We examined the associations of current alcohol consumption with brain morphometric measures in a healthy, community-dwelling cohort. Cranial T1-weighted 3D-structural MRI scans were obtain in 383 adults (men=211) aged 60-64 years, randomly selected form the larger PATH Through Life study. Voxel-based morphometric ana...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2007.08.009

    authors: Sachdev PS,Chen X,Wen W,Anstey KJ

    更新日期:2008-05-30 00:00:00

  • Identification of young people in the early stages of psychosis: validation of a checklist for use in primary care.

    abstract::The study aims to establish the concordant validity of the Early Detection Primary Care Checklist (PCCL); a 20 item tool designed to help primary care practitioners identify young people in the early stages of psychosis. The checklist was completed by the referring practitioners of 176 young people referred to early d...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2012.07.040

    authors: French P,Owens J,Parker S,Dunn G

    更新日期:2012-12-30 00:00:00

  • Meaning in meaninglessness: The propensity to perceive meaningful patterns in coincident events and randomly arranged stimuli is linked to enhanced attention in early sensory processing.

    abstract::Perception of objectively independent events or stimuli as being significantly connected and the associated proneness to perceive meaningful patterns constitute part of the positive symptoms of schizophrenia, which are associated with altered attentional processes in lateralized speech perception. Since perceiving mea...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.07.043

    authors: Rominger C,Schulter G,Fink A,Weiss EM,Papousek I

    更新日期:2018-05-01 00:00:00