Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32).

abstract：:Adult T-cell leukemia (ATL) is a fatal malignancy of CD4+ T cells infected with human T-cell leukemia virus type 1 (HTLV-1). ATL cells often exhibit random gross chromosomal rearrangements that are associated with the induction and improper repair of double-stranded DNA breaks (DSBs). The viral oncoprotein Tax has bee...

journal_title：Journal of virology

authors： Rushing AW,Hoang K,Polakowski N,Lemasson I

更新日期：2018-07-17 00:00:00

abstract：:The reovirus core particle is a molecular machine that mediates synthesis, capping, and export of the viral plus strand RNA transcripts. Its assembly and structure-function relationships remain to be well understood. Following the lead of previous studies with other Reoviridae family members, most notably orbiviruses ...

journal_title：Journal of virology

authors： Kim J,Zhang X,Centonze VE,Bowman VD,Noble S,Baker TS,Nibert ML

更新日期：2002-12-01 00:00:00

abstract：:Adenovirus E1B 55K protein cooperates with E1A gene products to induce cell transformation. E1B 55K mediates its effects by binding to and inhibiting the transcriptional activation and growth-suppression functions of the tumor suppressor p53. Previous studies in vivo have suggested that E1B 55K has an active role in r...

journal_title：Journal of virology

authors： Martin ME,Berk AJ

更新日期：1998-04-01 00:00:00

abstract：:Transcription of herpesviral late genes is stimulated after the onset of viral DNA replication but otherwise restricted. Late gene expression in gammaherpesviruses requires the coordination of six early viral proteins, termed viral transactivation factors (vTFs). Here, we mapped the organization of this protein comple...

journal_title：Journal of virology

authors： Davis ZH,Hesser CR,Park J,Glaunsinger BA

更新日期：2015-10-14 00:00:00

abstract：:Nucleotide sequence analysis of two simian virus 40 early mutants dl1263 and dl1265, which lack a DNA segment around map positions 0.21 and 0.18, respectively (C. Cole, T. Landers, S. Goff, S. MAnteuil-Brutlag, and P. Berg, J. Virol. 24:277--294, 1977), revealed in-phase deletions of 33 nucleotide pairs for dl1263 and...

journal_title：Journal of virology

authors： Van Heuverswyn H,Cole C,Berg P,Fiers W

更新日期：1979-06-01 00:00:00

abstract：:Redirecting the tropism of viral vectors enables specific transduction of selected cells by direct administration of vectors. We previously developed targeting lentiviral vectors by pseudotyping with modified Sindbis virus envelope proteins. These modified Sindbis virus envelope proteins have mutations in their origin...

journal_title：Journal of virology

authors： Morizono K,Ku A,Xie Y,Harui A,Kung SK,Roth MD,Lee B,Chen IS

更新日期：2010-07-01 00:00:00

abstract：:We describe initial genetic and structural characterizations of HK97, a temperate bacteriophage of Escherichia coli. We isolated 28 amber mutants, characterized them with respect to what phage-related structures they make, and mapped many of them to restriction fragments of genomic DNA. Sodium dodecyl sulfate-polyacry...

journal_title：Journal of virology

authors： Popa MP,McKelvey TA,Hempel J,Hendrix RW

更新日期：1991-06-01 00:00:00

abstract：:The Kansas strain of bovine parainfluenza virus type 3 (BPIV3) is 100- to 1,000-fold restricted in replication in the respiratory tracts of nonhuman primates compared to human PIV3 (HPIV3), an important pathogen of infants and young children. BPIV3 is also restricted in replication in human infants and children, yet i...

journal_title：Journal of virology

authors： Skiadopoulos MH,Schmidt AC,Riggs JM,Surman SR,Elkins WR,St Claire M,Collins PL,Murphy BR

更新日期：2003-01-01 00:00:00

abstract：:The use of endocytic pathways by viral glycoproteins is thought to play various functions during viral infection. We previously showed in transfection assays that herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) is transported from the cell surface back to the trans-Golgi network (TGN) and that two motifs of gB...

journal_title：Journal of virology

authors： Beitia Ortiz de Zarate I,Cantero-Aguilar L,Longo M,Berlioz-Torrent C,Rozenberg F

更新日期：2007-12-01 00:00:00

abstract：:All presently available replication-competent proviral clones of human immunodeficiency virus type 1 (HIV-1) are derived from cell culture-amplified virus. Since tissue culture is highly selective for viral strains with an in vitro growth advantage, such clones may not be representative of the biologically relevant vi...

journal_title：Journal of virology

authors： Li Y,Kappes JC,Conway JA,Price RW,Shaw GM,Hahn BH

更新日期：1991-08-01 00:00:00

abstract：:Kinetic analysis showed that the Ki values and the Ki/Km ratios for mutated, recombinant M184V human immunodeficiency virus type 1 reverse transcriptase (RT) for (-)2'-dideoxy-3'-thiacytidine triphosphate (3TCTP) were 35-fold higher than the equivalent values for wild-type RT but only about twice as high as the equiva...

journal_title：Journal of virology

authors： Quan Y,Gu Z,Li X,Li Z,Morrow CD,Wainberg MA

更新日期：1996-08-01 00:00:00

abstract：:Adenovirus type 35 (Ad35) is a group B adenovirus that has been isolated primarily from patients with acquired immunodeficiency syndrome and other immunodeficiency disorders. We have studied the interaction of this unique adenovirus with the immune system by analyzing Ad35 early viral proteins in infected HeLa cells. ...

journal_title：Journal of virology

authors： Flomenberg PR,Chen M,Horwitz MS

更新日期：1987-12-01 00:00:00

abstract：:The key role of the mitochondria in the regulation of cellular Ca2+ led to a study of mitochondrial Ca2+ uptake during the infection of chicken embryo cells with Semliki Forest virus. Mitochondrial Ca2+ uptake was stimulated during the first 5 h of infection but declined later in infection. The early stimulation sugge...

journal_title：Journal of virology

authors： Peterhans E,Haenggeli E,Wild P,Wyler R

更新日期：1979-01-01 00:00:00

abstract：:Borna disease virus infection is diagnosed by the presence of serum antibodies reactive with the major viral proteins, p40 and p23. Although p40 and p23 are unrelated in amino acid sequence structure, cross-reactive antibodies are described. Protein fragments and synthetic peptides were analyzed to characterize the sp...

journal_title：Journal of virology

authors： Kliche S,Stitz L,Mangalam H,Shi L,Binz T,Niemann H,Briese T,Lipkin WI

更新日期：1996-11-01 00:00:00

abstract：:A rapid assay for retroviral reverse transcriptase activity released into the culture medium by infected cells was developed. With the assay, 4,000 clonally infected cell lines could be tested in a few hours. We have adapted the assay for use as a screen for the detection of spontaneous viral mutants. Mutants of Molon...

journal_title：Journal of virology

authors： Goff S,Traktman P,Baltimore D

更新日期：1981-04-01 00:00:00

abstract：:N6-adenosine methylation (m6A) is the most common posttranscriptional RNA modification in mammalian cells. We found that most transcripts encoded by the Kaposi's sarcoma-associated herpesvirus (KSHV) genome undergo m6A modification. The levels of m6A-modified mRNAs increased substantially upon stimulation for lytic re...

journal_title：Journal of virology

authors： Ye F,Chen ER,Nilsen TW

更新日期：2017-07-27 00:00:00

abstract：:The Borna disease virus (BDV) is the prototype member of the Bornaviridae, and it replicates in the cell nucleus. The BDV p24P and p40N proteins carry nuclear localization signals (NLS) and are found in the nuclei of infected cells. The BDV p10 protein does not have an NLS, but it binds with P and/or N and is transloc...

journal_title：Journal of virology

authors： Malik TH,Kishi M,Lai PK

更新日期：2000-04-01 00:00:00

abstract：:Adenoviral RNA sequences synthesized in nuclei isolated during the late phase of productive infection comprise, besides virus-associated, VA, RNA, five major species, ranging in size from approximately 13S to 55S. The latter RNA species is of the length predicted if the major transcriptional unit expressed during the ...

journal_title：Journal of virology

authors： Yang VW,Flint SJ

更新日期：1979-11-01 00:00:00

abstract：UNLABELLED:During HIV-1 assembly, the Gag viral proteins are targeted and assemble at the inner leaflet of the cell plasma membrane. This process could modulate the cortical actin cytoskeleton, located underneath the plasma membrane, since actin dynamics are able to promote localized membrane reorganization. In additio...

journal_title：Journal of virology

authors： Thomas A,Mariani-Floderer C,López-Huertas MR,Gros N,Hamard-Péron E,Favard C,Ohlmann T,Alcamí J,Muriaux D

更新日期：2015-08-01 00:00:00

abstract：:Coxsackievirus B3 (CVB3) is an enterovirus in the family Picornaviridae that is significant to human health, being associated with myocarditis, aseptic meningitis, and pancreatitis, among other conditions. In addition to humans, Sichuan snub-nosed monkeys can be infected and killed by CVB3. Here, we report the first c...

journal_title：Journal of virology

authors： He W,Lu H,Zhao K,Song D,Gai X,Gao F

更新日期：2012-12-01 00:00:00

abstract：:We have previously shown that the herpes simplex virus immediate-early regulatory protein ICP27 acts posttranscriptionally to affect mRNA processing (R. M. Sandri-Goldin and G. E. Mendoza, Genes Dev. 6:848-863, 1992). Specifically, in the presence of ICP27, spliced target mRNAs were decreased 5- to 10-fold in transfec...

journal_title：Journal of virology

authors： Hardwicke MA,Sandri-Goldin RM

更新日期：1994-08-01 00:00:00

abstract：:A series of recombinant molecules were constructed which direct the expression of the easily assayed gene chloramphenicol acetyltransferase. We have used these recombinants to show that the 73/72-base-pair tandem repeat unit from the Moloney murine sarcoma virus long terminal repeat shares a number of properties with ...

journal_title：Journal of virology

authors： Laimins LA,Gruss P,Pozzatti R,Khoury G

更新日期：1984-01-01 00:00:00

abstract：:The nucleotide sequences of the termini of the mature pseudorabies virus genome and of the junction between these termini in concatemeric DNA were compared. To ensure conservation of unmodified 5' and 3' termini, the end fragments obtained directly (uncloned) from mature viral DNA were sequenced. The sequence obtained...

journal_title：Journal of virology

authors： Harper L,Demarchi J,Ben-Porat T

更新日期：1986-12-01 00:00:00

abstract：:The Nef proteins of human immunodeficiency virus and simian immunodeficiency virus (SIV) bind the AP-1 and AP-2 clathrin adaptors to downmodulate the expression of CD4 and CD28 by recruiting them to sites of AP-2 clathrin-dependent endocytosis. Additionally, SIV Nef directly binds the CD3-zeta subunit of the CD3 compl...

journal_title：Journal of virology

authors： Swigut T,Greenberg M,Skowronski J

更新日期：2003-07-01 00:00:00

abstract：:Through their hemagglutinin-neuraminidase glycoprotein, parainfluenza viruses bind to sialic acid-containing glycoconjugates to initiate infection. Although the virus-receptor interaction is a key factor of infection, the exact nature of the receptors that human parainfluenza viruses recognize has not been determined....

journal_title：Journal of virology

authors： Suzuki T,Portner A,Scroggs RA,Uchikawa M,Koyama N,Matsuo K,Suzuki Y,Takimoto T

更新日期：2001-05-01 00:00:00

abstract：:Previously we have described a stepwise, energy-dependent pathway for human immunodeficiency virus type 1 (HIV-1) capsid assembly in a cell-free system. In this pathway, Gag polypeptides utilize the cellular factor HP68 and assemble into immature capsids by way of assembly intermediates that have defined biochemical c...

journal_title：Journal of virology

authors： Dooher JE,Lingappa JR

更新日期：2004-02-01 00:00:00

abstract：:We previously described that type B retrovirus-like particles released from the human mammary carcinoma cell line T47D are pseudotypes and package retroviral RNA of different origins (W. Seifarth, H. Skladny, F. Krieg-Schneider, A. Reichert, R. Hehlmann, and C. Leib-Mösch, J. Virol. 69:6408-6416, 1995). One preferenti...

journal_title：Journal of virology

authors： Seifarth W,Baust C,Murr A,Skladny H,Krieg-Schneider F,Blusch J,Werner T,Hehlmann R,Leib-Mösch C

更新日期：1998-10-01 00:00:00

abstract：:Circoviruses are small, nonenveloped icosahedral animal viruses characterized by circular single-stranded DNA genomes. Their genomes are the smallest possessed by animal viruses. Infections with circoviruses, which can lead to economically important diseases, frequently result in virus-induced damage to lymphoid tissu...

journal_title：Journal of virology

authors： Crowther RA,Berriman JA,Curran WL,Allan GM,Todd D

更新日期：2003-12-01 00:00:00

abstract：:The pregenomic RNA (pgRNA) of hepatitis B virus (HBV) serves as the messenger for both core and P proteins, with the downstream P gene translated by ribosomal leaky scanning. HBV replication begins with packaging of the pgRNA and P protein into core protein particles, followed by conversion of RNA into DNA. Genotype G...

journal_title：Journal of virology

authors： Gutelius D,Li J,Wands J,Tong S

更新日期：2011-12-01 00:00:00

abstract：:Infection of newborn Lewis rats with Borna disease virus (neonatal Borna disease [NBD]) results in cerebellar damage without the cellular inflammation associated with infections in later life. Purkinje cell (PC) damage has been reported for several models of early-life viral infection, including NBD; however, the time...

journal_title：Journal of virology

authors： Williams BL,Yaddanapudi K,Hornig M,Lipkin WI

更新日期：2007-03-01 00:00:00