Morphological changes and selective loss of motoneurons in the lumbar part of the spinal cord in a rat model of familial amyotrophic lateral sclerosis (fALS).

abstract：INTRODUCTION:Transsphenoidal surgery is the treatment of choice in Cushing's disease (CD), although even late recurrences occur in some patients. Low expression of O-6-methylguanine-DNA methyltransferase (MGMT) has been linked to a high risk of relapse in pituitary tumours, but the evidence for corticotroph adenomas is...

journal_title：Folia neuropathologica

authors： Witek P,Maksymowicz M,Szamotulska K,Piaścik A,Wojciechowska-Luźniak A,Stasiewicz A,Witek J,Zieliński G

更新日期：2020-01-01 00:00:00

abstract：:Idiopathic hypertrophic pachymeningitis (IHPM) is a rare pathological state, with still unclear aetiopathogenesis. We present a case of a 63-year-old woman with cranial variety of that disease. The manifestations of the disease included headaches, paresis of VI, IX, X nerves and cerebellar ataxia. The disease was diag...

journal_title：Folia neuropathologica

authors： Rudnik A,Larysz D,Gamrot J,Rudnik A,Skorupa A,Bierzyńska-Macyszyn G,Bazowski P

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND STUDY PURPOSE:due to the fact that an interrelation between metastases of lung cancer to the brain and surroundings may influence the prognosis, we made attempts to answer the following questions: 1) how is the border between the tumour and its surroundings formed? 2) are there any differences in the gli...

journal_title：Folia neuropathologica

authors： Tabaka J,Nowacki P,Pankowski J

更新日期：2006-01-01 00:00:00

abstract：:We have determined the cellular concentration of thyroxine (T4) and triiodothyronine (T3) and the activities of two brain iodothyronine deiodinases, type II (5'-D2) and type III (5-D3), in two types of tissues --tumour (26) and non-tumour (5), derived either from human gliomas with various histological malignancies or...

journal_title：Folia neuropathologica

authors： Nauman P,Bonicki W,Michalik R,Warzecha A,Czernicki Z

更新日期：2004-01-01 00:00:00

abstract：:Myositis specific autoantibodies (MSA) are the most specific markers of idiopathic inflammatory myopathies (IIM). There is no evidence of presence MSA in patients with other neuromuscular or connective tissue diseases. We compared the frequency of MSA in two groups of IIM patients, one from Poland and one from North A...

journal_title：Folia neuropathologica

authors： Kowalska-Oledzka E,Stern LZ

更新日期：2000-01-01 00:00:00

abstract：:The Warburg micro syndrome (WARBM) is a genetically heterogeneous syndrome linked to at least 4 loci. At the clinical level, WARBM is characterized by microcephaly, microphthalmia, microcornea, congenital cataracts, corpus callosum hypoplasia, severe mental retardation, and hypogonadism. In some families additional cl...

journal_title：Folia neuropathologica

authors： Kabzińska D,Mierzewska H,Senderek J,Kochański A

更新日期：2016-01-01 00:00:00

abstract：:The analysis of qualitative changes in the locus coeruleus (LC) was performed on brains from 21 cases of Parkinson's disease. Eleven cases were selected for quantitative analysis of the loss of LC noradrenergic pigmented neurons. The qualitative studies revealed uneven dissemination of the noradrenergic cells loss of ...

journal_title：Folia neuropathologica

authors： Bertrand E,Lechowicz W,Szpak GM,Dymecki J

更新日期：1997-01-01 00:00:00

abstract：:Increased pineal calcifications and decreased pineal melatonin biosynthesis, both age related, support the notion of a pineal bio-organic timing mechanism. The role of calcification in the pathogenesis of pineal gland dysfunction remains unknown but the available data document that calcification is an organized, regul...

journal_title：Folia neuropathologica

authors： Maślińska D,Laure-Kamionowska M,Deręgowski K,Maśliński S

更新日期：2010-01-01 00:00:00

abstract：:The endothelial vacuolar and vesicular transports in traumatic human brain oedema have been reviewed and compared with experimental brain oedema in order to establish their role in both oedema formation and oedema resolution. Normal or "non-activated" and "activated" capillaries are found. The activated capillaries sh...

journal_title：Folia neuropathologica

authors： Castejón OJ

更新日期：2013-01-01 00:00:00

abstract：:The pineal gland is an organ involved in regulation of homeostasis and body rhythms. It plays an important role in the growth foetuses and adaptation of newborns to new environmental conditions. The requirements of foetuses and newborns progressively change during development. The purpose of the study was to evaluate ...

journal_title：Folia neuropathologica

authors： Laure-Kamionowska M,Maślińska D,Deregowski K,Czichos E,Raczkowska B

更新日期：2003-01-01 00:00:00

abstract：:The inflammatory process is a nonspecific complex, stereotype, coordinated response of tissues to injury. This process involves vascular permeability, active migration of blood cells, and passage of plasma constituents into the injurious tissue. The molecules that mediate the initial events of inflammation are the adh...

journal_title：Folia neuropathologica

authors： Maślińska D,Gajewski M

更新日期：1998-01-01 00:00:00

abstract：:The object of our report is the presentation of the morphological picture of cerebellar cortex malformation as a sequel of disturbed neuronal migration. In the disarranged tissue, cavities with a network of meningeal tissue and embedded pathological vessels were noted. The external granule cells did not form a proper ...

journal_title：Folia neuropathologica

authors： Laure-Kamionowska M,Taraszewska A,Maślińska D,Raczkowska B

更新日期：2006-01-01 00:00:00

abstract：:There is an increased risk of stroke in patients with HIV infection. One of the mechanisms is production of anticardiolipin (aCL) antibodies, induced by the virus. Many studies have documented a high incidence of aCL antibodies in patients with HIV infection and the increased risk of stroke, although there is no such ...

journal_title：Folia neuropathologica

authors： Gorczyca I,Stanek M,Podlasin B,Furmanek M,Pniewski J

更新日期：2005-01-01 00:00:00

abstract：:Forty human primary brain tumors: twelve protoplasmic, six gemistocytic, four fibrillary and ten anaplastic astrocytomas, eight glioblastomas were submitted for immunohistochemical and histochemical characterization of microglia in tumor tissue and in its surroundings. The following antibodies were used: GFAP, ferriti...

journal_title：Folia neuropathologica

authors： Wierzba-Bobrowicz T,Kuchna I,Matyja E

更新日期：1994-01-01 00:00:00

abstract：:Metallothioneins (MT) are common proteins in animal tissues. These proteins take part in the homeostasis of the ions of the metals which are necessary for the proper metabolism of the organism (zinc, copper), biosynthesis regulation and zincprotein activity (for example the activity of the zinc-dependant transcription...

journal_title：Folia neuropathologica

authors： Floriańczyk B,Osuchowski J,Kaczmarczyk R,Starosławska E,Trojanowski T

更新日期：2005-01-01 00:00:00

abstract：:The ultrastructural pathology of cerebral cortex in human hydrocephalus is reviewed and compared with experimental hydrocephalus. Nerve cells show moderate and severe swelling. The neighboring neuropil exhibits notable enlargement of extracellular space, synaptic plasticity and degeneration, damage of myelinated axons...

journal_title：Folia neuropathologica

authors： Castejón OJ

更新日期：2010-01-01 00:00:00

abstract：:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the NOTCH3 gene. Pathophysiologically, there seems to be multimerization of the extracellular domain of the protein with a possible gain of function on vascular smooth muscular cells. However,...

journal_title：Folia neuropathologica

authors： Erro R,Moccia M,Cervasio M,Penco S,De Caro Mdel B,Barone P

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:During human myogenesis and synaptogenesis, the first contact between multiaxonal nerve terminals and the primary myotube occurs at an early stage of gestation, then monoaxonal nerve terminals form and postsynaptic clusters of acetylcholine-receptor are modified and redistributed to the site of muscle-nerv...

journal_title：Folia neuropathologica

authors： Fidziańska A,Jędrzejowska M,Madej-Pilarczyk A,Bojakowski J

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Subependymal nodule (SEN) and subependymal giant cell astrocytoma (SEGA) are brain lesions frequently found in tuberous sclerosis (TS). As about 10-15% of SENs enlarge and transform into SEGAs, we examined here the possible mechanism of the phenomenon. MATERIAL AND METHODS:Using Western blot we studied 1 ...

journal_title：Folia neuropathologica

authors： Siedlecka M,Szlufik S,Grajkowska W,Roszkowski M,Jóźwiak J

更新日期：2015-01-01 00:00:00

abstract：:Angiocentric glioma (AG) is a newly-classified, very rare, WHO grade I central nervous system (CNS) lesion, occurring usually in children and young adults. Only 52 patients with AG have been reported so far, making it one of the rarest neuropathological entities. Hereby we present two new cases of AG in young subjects...

journal_title：Folia neuropathologica

authors： Adamek D,Siwek GP,Chrobak AA,Herman-Sucharska I,Kwiatkowski S,Morga R,Radwańska E,Urbanowicz B

更新日期：2016-01-01 00:00:00

abstract：:Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare transmissible disease caused by accumulation of pathological prion protein in the CNS. sCJD typically affects patients in their sixties. The median disease duration in sCJD (6 months) is shorter than in variant Creutzfeldt-Jakob disease (vCJD) (14 months). The clinic...

journal_title：Folia neuropathologica

authors： Krasnianski A,Meissner B,Heinemann U,Zerr I

更新日期：2004-01-01 00:00:00

abstract：:Neuronal and axonal degenerative changes in motor vagal neurons (DMNV) and sensory vagal neurons (nTS) in the medulla oblongata in newborns were studied. Material was taken from the autopsies of newborns, live and dead newborns, in different gestational weeks (aborted, immature, premature and mature). 46 cases were st...

journal_title：Folia neuropathologica

authors： Islami H,Shabani R,Shabani D,Dacaj R,Manxhuka S,Azemi M,Krasniqi S,Kurtishi I

更新日期：2011-01-01 00:00:00

abstract：:We present a case of rare orbital roof haemangioma infiltrating the medial and lateral walls of the orbit, zygomatic bone and lesser and greater wings of the sphenoid. The tumour was totally excised by the frontolateral approach, followed by craniofacial and orbital roof reconstruction. ...

journal_title：Folia neuropathologica

authors： Kolasa P,Januszalwasiak,Kordek R,Boroński K

更新日期：2001-01-01 00:00:00

abstract：:The aim of the study was to analyse in TEM the evolution of changes in structural elements of synaptic junctions of the cerebellar cortex in rats in valproate encephalopathy induced by chronic 12-month administration of sodium valproate - VPA (once daily intragastrically, in a dose of 200 mg/kg b.w.) and after withdra...

journal_title：Folia neuropathologica

authors： Sobaniec-Lotowska ME

更新日期：2002-01-01 00:00:00

abstract：:Electron microscopic immunocytochemical evaluation of localization and distribution of endothelins 1, 2 and 3 in the CA1 hippocampal sector in rats submitted to 10 min global cerebral ischemia was performed. The studies were done in different postischemic periods (10 min, 3, 6, 12 and 24 h) with postembedding immuno-g...

journal_title：Folia neuropathologica

authors： Gajkowska B,Mossakowski MJ

更新日期：1995-01-01 00:00:00

abstract：:The importance of chemokines seems to extend far beyond their well-known role as mediators of an inflammatory response. The most interesting hypothesis is that these molecules may influence the migration of progenitor cells during development. Primary sensory neurones have been shown to migrate towards RANTES in vitro...

journal_title：Folia neuropathologica

authors： Geppert AM

更新日期：2003-01-01 00:00:00

abstract：INTRODUCTION:Activated microglia produce neurotoxic factors, including pro-inflammatory cytokines and nitric oxide (NO), in response to neuronal destruction. Therapeutic suppression of microglial release of these factors by various approaches including hypothermia is considered to be neuroprotective after severe brain ...

journal_title：Folia neuropathologica

authors： Matsui T,Kida H,Iha T,Obara T,Nomura S,Fujimiya T,Suzuki M

更新日期：2014-01-01 00:00:00

abstract：:A neuropathological analysis of 172 cases of AIDS in adults was carried out, to determine the occurrence and nature of the opportunistic infections of the central nervous system (CNS). The material comprised 155 cases of men, and 17 women. Mean age of patients was 38 years. Collection under study originated from the p...

journal_title：Folia neuropathologica

authors： Zelman IB,Mossakowski MJ

更新日期：1998-01-01 00:00:00

abstract：:A fetal, cryopreserved ventral mesencephalic rat tissue was transplanted into striatum of healthy adult rats. A stereotactic apparatus was used for transplantation of solid tissue blocks. The survival of transplanted dopaminergic cells in rat striatum was evaluated by means of histological and immunocytochemical metho...

journal_title：Folia neuropathologica

authors： Kosno-Kruszewska E,Wierzba-Bobrowicz T,Ilnicki K,Lechowicz W,Dymecki J

更新日期：1996-01-01 00:00:00

abstract：:During embryogenesis, about 40% of genes are involved in the development of the central nervous system (CNS). The same genes support the integrity and function of brain cells in humans. Birth defects cause different changes in genetic material during embryogenesis. They may also be responsible for precocious death of ...

journal_title：Folia neuropathologica

authors： Schmidt-Sidor B,Mierzewska H,Turzyniecka M,Kowalewska-Kantecka B,Wierzba-Bobrowicz T,Lechowicz W

更新日期：2004-01-01 00:00:00