Might prepatterned acetylcholine-receptor clusters on surface myotubes be a sign of neuromuscular-junction maturation failure?

abstract：:A contribution of B cells and autoantibodies has been demonstrated in MS leading to interest in the use of such autoantibodies as diagnostic or prognostic markers and as a basis for immunomodulatory therapy. ELISA and Western fail to detect reactivity against epitopes displayed by native antigens expressed on myelin s...

journal_title：Folia neuropathologica

authors： Jaśkiewicz E,Michałowska-Wender G,Pyszczek A,Wender M

更新日期：2010-01-01 00:00:00

abstract：:There is an increased risk of stroke in patients with HIV infection. One of the mechanisms is production of anticardiolipin (aCL) antibodies, induced by the virus. Many studies have documented a high incidence of aCL antibodies in patients with HIV infection and the increased risk of stroke, although there is no such ...

journal_title：Folia neuropathologica

authors： Gorczyca I,Stanek M,Podlasin B,Furmanek M,Pniewski J

更新日期：2005-01-01 00:00:00

abstract：:Epithelioid schwannomas occur predominantly in relation to peripheral nerves and are associated with histological and clinical malignancy. However, a variant of the epithelioid schwannoma involving cranial nerves is extremely rare. In this study we report three cases of epithelioid schwannomas originating from the aco...

journal_title：Folia neuropathologica

authors： Kroh H,Matyja E,Marchel A

更新日期：2000-01-01 00:00:00

abstract：:Granular osmiophilic material (GOM) is a pathognomonic feature of CADASIL that may be a consequence of pathological processes triggered by Notch3 mutations. Since knowledge of the effects of CADASIL-associated GOM deposits is important to understand the molecular pathogenesis of this disorder, we performed a thorough ...

journal_title：Folia neuropathologica

authors： Lewandowska E,Dziewulska D,Parys M,Pasennik E

更新日期：2011-01-01 00:00:00

abstract：:Telepathology is the diagnostic work of a pathologist at a distance. It includes specific application fields which require specific system solutions. These comprise: a. frozen section service; b. expert consultations; c. remote control measurements, and d. education and training. Applications but, in addition, all asp...

journal_title：Folia neuropathologica

authors： Kayser K,Beyer M,Blum S,Kayser G

更新日期：2000-01-01 00:00:00

abstract：:Forty human primary brain tumors: twelve protoplasmic, six gemistocytic, four fibrillary and ten anaplastic astrocytomas, eight glioblastomas were submitted for immunohistochemical and histochemical characterization of microglia in tumor tissue and in its surroundings. The following antibodies were used: GFAP, ferriti...

journal_title：Folia neuropathologica

authors： Wierzba-Bobrowicz T,Kuchna I,Matyja E

更新日期：1994-01-01 00:00:00

abstract：:Myositis specific autoantibodies (MSA) are the most specific markers of idiopathic inflammatory myopathies (IIM). There is no evidence of presence MSA in patients with other neuromuscular or connective tissue diseases. We compared the frequency of MSA in two groups of IIM patients, one from Poland and one from North A...

journal_title：Folia neuropathologica

authors： Kowalska-Oledzka E,Stern LZ

更新日期：2000-01-01 00:00:00

abstract：:We demonstrate an unusually intensive accumulation of prion protein (PrP) on neuronal membranes in hamsters infected with the Echigo-1 panencephalopathic strain of Creutzfeldt-Jakob disease. This stands in strong contrast with the poor vacuolation in this model. Several distinct patterns of PrP(TSE) deposit were obser...

journal_title：Folia neuropathologica

authors： Liberski PP,Hainfellner JA,Sikorska B,Mori S,Budka H

更新日期：2004-01-01 00:00:00

abstract：:The visual cortex undergoes age related changes that have been studied mainly in rats Maccaca Mulata, and human beings. Despite the fact that there is no extensive neuronal loss in aged brains, a lot of important pathological changes are found in the morphology of the neurons. The present study describes the morpholog...

journal_title：Folia neuropathologica

authors： Mavroudis I,Petrides F,Manani M,Theocharides C,Ciobica A,Padurariu M,Kiourexidou M,Njau S,Costa V,Baloyannis S

更新日期：2012-01-01 00:00:00

abstract：:The endothelial vacuolar and vesicular transports in traumatic human brain oedema have been reviewed and compared with experimental brain oedema in order to establish their role in both oedema formation and oedema resolution. Normal or "non-activated" and "activated" capillaries are found. The activated capillaries sh...

journal_title：Folia neuropathologica

authors： Castejón OJ

更新日期：2013-01-01 00:00:00

abstract：:The aim of our study was the estimation of the apoptosis process using in situ-end labelling of DNA breaks method on paraffin sections in 5 human cases of Alzheimer's disease (AD), 6 of Creutzfeldt-Jakob disease (CJD) and in 25 mice infected experimentally with the Fujisaki strain of CJD, killed sequentially at one-we...

journal_title：Folia neuropathologica

authors： Jesionek-Kupnicka D,Buczyński J,Kordek R,Sobów T,Kłoszewska I,Papierz W,Liberski PP

更新日期：1997-01-01 00:00:00

abstract：:Idiopathic hypertrophic pachymeningitis (IHPM) is a rare pathological state, with still unclear aetiopathogenesis. We present a case of a 63-year-old woman with cranial variety of that disease. The manifestations of the disease included headaches, paresis of VI, IX, X nerves and cerebellar ataxia. The disease was diag...

journal_title：Folia neuropathologica

authors： Rudnik A,Larysz D,Gamrot J,Rudnik A,Skorupa A,Bierzyńska-Macyszyn G,Bazowski P

更新日期：2007-01-01 00:00:00

abstract：:A case of 56-year-old male with sarcomatosis of leptomeninges as well as of the brain and spinal cord coexisting with Recklinghausen's neurofibromatosis is presented. Neurological and neurophysiological symptoms of the disease resembled those of amyotrophic lateral sclerosis (ALS). Patient died 7 months after onset of...

journal_title：Folia neuropathologica

authors： Słowiński J,Adamek D,Krygowska-Wajs A,Rudzińska M,Kałuza J

更新日期：1995-01-01 00:00:00

abstract：:The post-mortem neuropathological investigations were carried out on 20 female New Zealand rabbits. Two main types of changes were found: inflammatory, including meningeal and perivascular infiltrates, and thrombotic within the nervous tissue. The findings revealed that active process within the CNS persists at least ...

journal_title：Folia neuropathologica

authors： Nowacki P,Ronin-Walknowska E,Ossowicka-Stepińska J

更新日期：1999-01-01 00:00:00

abstract：:The analysis of qualitative changes in the locus coeruleus (LC) was performed on brains from 21 cases of Parkinson's disease. Eleven cases were selected for quantitative analysis of the loss of LC noradrenergic pigmented neurons. The qualitative studies revealed uneven dissemination of the noradrenergic cells loss of ...

journal_title：Folia neuropathologica

authors： Bertrand E,Lechowicz W,Szpak GM,Dymecki J

更新日期：1997-01-01 00:00:00

abstract：:We report the case of an 84-year-old male patient afflicted by cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) showing minimal symptoms of disease. The patient was diagnosed on the basis of ultrastructural and genetic examinations. Ultrastructurally, a typical vascu...

journal_title：Folia neuropathologica

authors： Lewandowska E,Felczak P,Buczek J,Gramza K,Rafałowska J

更新日期：2014-01-01 00:00:00

abstract：:The 'prion-like' transfer of pathogenic proteins may play a role in the pathogenesis of frontotemporal lobar degeneration (FTLD). Propagation of such proteins along anatomical pathways may give rise to specific spatial patterns of the 'signature' neuronal cytoplasmic inclusions (NCI) characteristic of these disorders....

journal_title：Folia neuropathologica

authors： A Armstrong R

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary, progressive ischemic disease of small vessels of the brain characterized by migraine with aura (MA), recurrent subcortical ischemic episodes, cognitive decline and psychiatric disorders. CA...

journal_title：Folia neuropathologica

authors： Dorszewska J,Kowalska M,Grzegorski T,Dziewulska D,Karmelita-Katulska K,Barciszewska AM,Prendecki M,Gorczyński W,Kozubski W

更新日期：2020-01-01 00:00:00

abstract：:The effect of transient, global cerebral ischemia on the distribution of endothelin (ET) in blood-brain barrier (BBB) in CA1 area of hippocampus long-time after ischemia was estimated using post-embedding immunogold technique. ET-like immunoreactivity as a gold particles was localized in all compartments of the blood-...

journal_title：Folia neuropathologica

authors： Gajkowska B,Mossakowski MJ

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The efficacy of tempol and its acyl derivative tempol-C8 as retinoprotective agents was compared in a rat model of NMDA-induced retinal ganglion cell (RGC) damage. MATERIAL AND METHODS:Tempol or tempol-C8 in different doses was administered intraperitoneally to 6 weeks old (pre-adolescent) and 9-10 weeks ol...

journal_title：Folia neuropathologica

authors： Fiedorowicz M,Rejdak R,Schuettauf F,Wozniak M,Grieb P,Thaler S

更新日期：2014-01-01 00:00:00

abstract：:A neuropathological analysis of 172 cases of AIDS in adults was carried out, to determine the occurrence and nature of the opportunistic infections of the central nervous system (CNS). The material comprised 155 cases of men, and 17 women. Mean age of patients was 38 years. Collection under study originated from the p...

journal_title：Folia neuropathologica

authors： Zelman IB,Mossakowski MJ

更新日期：1998-01-01 00:00:00

abstract：:Meningiomas are the most common primary extra-axial tumours of the central nervous system, however their metastatic spread beyond central nervous system is rare. Here we present the case of a 54-year-old male with anaplastic meningioma who, 1.5 years after initial diagnosis, developed a tumorous expansion in his left ...

journal_title：Folia neuropathologica

authors： Soukup J,Kasparova P,Vajda M,Ryska A

更新日期：2019-01-01 00:00:00

abstract：:The clinical and histological picture and immunocytochemical expression of some cytokines on infiltrates in the central nervous system of Lewis rats were studied in adult rats in the course of short-term therapy of acute experimental allergic encephalomyelitis with interferon beta 1a (IFN beta 1a). There was establish...

journal_title：Folia neuropathologica

authors： Wender M,Michalak S,Wygladalska-Jernas H

更新日期：2001-01-01 00:00:00

abstract：:Metallothioneins take part in the homeostasis of the ions of the metals which are necessary for the proper metabolism of the organism (zinc, copper), in biosynthesis regulation of the zinc-containing proteins and also in the detoxication of metals from the tissues. They also protect the tissue from the effects of free...

journal_title：Folia neuropathologica

authors： Floriańczyk B,Osuchowski J,Kaczmarczyk R,Trojanowski T,Stryjecka-Zimmer M

更新日期：2003-01-01 00:00:00

abstract：:Introduction: Mixed dementia (MixD) refers to a combination of definite Alzheimer's disease (AD) and vascular encephalopathy. The existence of a "pure" type of vascular dementia (VaD) is controversial. There is a need to find magnetic resonance imaging (MRI) characteristics allowing the distinction between V...