Submicroscopic pathology of human and experimental hydrocephalic cerebral cortex.

abstract：:The qualitative analysis of changes in major nuclei (n. paranigralis left and right, n. interfascicularis) of the mesocorticolimbic system (ventral tegmental area-VTA) was carried out on 25 cases with Parkinson's disease (PD). The cellular depletion with insignificant gliosis without the presence of macrophages was fo...

journal_title：Folia neuropathologica

authors： Dymecki J,Lechowicz W,Bertrand E,Szpak GM

更新日期：1996-01-01 00:00:00

abstract：:The object of our report is the presentation of the morphological picture of cerebellar cortex malformation as a sequel of disturbed neuronal migration. In the disarranged tissue, cavities with a network of meningeal tissue and embedded pathological vessels were noted. The external granule cells did not form a proper ...

journal_title：Folia neuropathologica

authors： Laure-Kamionowska M,Taraszewska A,Maślińska D,Raczkowska B

更新日期：2006-01-01 00:00:00

abstract：:The pineal gland is an organ involved in regulation of homeostasis and body rhythms. It plays an important role in the growth foetuses and adaptation of newborns to new environmental conditions. The requirements of foetuses and newborns progressively change during development. The purpose of the study was to evaluate ...

journal_title：Folia neuropathologica

authors： Laure-Kamionowska M,Maślińska D,Deregowski K,Czichos E,Raczkowska B

更新日期：2003-01-01 00:00:00

abstract：:There is an increased risk of stroke in patients with HIV infection. One of the mechanisms is production of anticardiolipin (aCL) antibodies, induced by the virus. Many studies have documented a high incidence of aCL antibodies in patients with HIV infection and the increased risk of stroke, although there is no such ...

journal_title：Folia neuropathologica

authors： Gorczyca I,Stanek M,Podlasin B,Furmanek M,Pniewski J

更新日期：2005-01-01 00:00:00

abstract：:Globoid cell leukodystrophy (GLD, also known as Krabbe disease), whose pathophysiology is still not completely elucidated, is an inherited, metabolic, and neurodegenerative disease, caused by the deficiency of β-galactocerebrosidase (GALC) or in very rare cases by lack of active saposin A. We describe two patients, i...

journal_title：Folia neuropathologica

authors： Szymańska K,Ługowska A,Laure-Kamionowska M,Bekiesińska-Figatowska M,Gieruszczak-Białek D,Musielak M,Eichler S,Giese AK,Rolfs A

更新日期：2012-01-01 00:00:00

abstract：:In the present work, we investigated the effect of chronic haloperidol administration on the number of striatal neurons in guinea pigs. For this purpose, adult male guinea pigs were given daily injections of 1, 2 or 3 mg/kg of haloperidol for 6 weeks. After treatment, the animals were anesthetized via brief inhalation...

journal_title：Folia neuropathologica

authors： Altunkaynak BZ,Ozbek E,Aydin N,Aydin MD,Altunkaynak ME,Vuraler O,Unal B

更新日期：2011-01-01 00:00:00

abstract：:Metallothioneins (MT) are common proteins in animal tissues. These proteins take part in the homeostasis of the ions of the metals which are necessary for the proper metabolism of the organism (zinc, copper), biosynthesis regulation and zincprotein activity (for example the activity of the zinc-dependant transcription...

journal_title：Folia neuropathologica

authors： Floriańczyk B,Osuchowski J,Kaczmarczyk R,Starosławska E,Trojanowski T

更新日期：2005-01-01 00:00:00

abstract：:Neuroacanthocytosis is a rare disease of nervous system with multisystem pathology. This review presents clinical syndromes and morphological changes of sporadic and familial forms of neuroacanthocytosis and is illustrated by the case of a 27-year-old man. Progressive extrapyramidal syndrome appeared at the age of 22....

journal_title：Folia neuropathologica

authors： Rafałowska J,Drac H,Jamrozik Z

更新日期：1996-01-01 00:00:00

abstract：:Cerebellar degeneration belongs to indirect effects of malignancy on the nervous system. Although the involvement of immune system is accepted as a hypothesis of its pathology, the clinical observations of ineffective immunomodulatory therapy suggest complex pathomechanisms, which await elucidation. The aim of this st...

journal_title：Folia neuropathologica

authors： Michalak S,Wender M,Michalowska-Wender G,Kozubski W

更新日期：2010-01-01 00:00:00

abstract：:Granular osmiophilic material (GOM) is a pathognomonic feature of CADASIL that may be a consequence of pathological processes triggered by Notch3 mutations. Since knowledge of the effects of CADASIL-associated GOM deposits is important to understand the molecular pathogenesis of this disorder, we performed a thorough ...

journal_title：Folia neuropathologica

authors： Lewandowska E,Dziewulska D,Parys M,Pasennik E

更新日期：2011-01-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is a potent immunogen when administered locally and/or systemically. The peripheral immunization with LPS could contribute to the progression of neurological diseases because a strong link between neuroinflammation and dopaminergic degeneration has been found. The switch between the survival a...

journal_title：Folia neuropathologica

authors： Hernandez Baltazar D,Nadella R,Barrientos Bonilla A,Flores Martínez Y,Olguín A,Heman Bozadas P,Rovirosa Hernández M,Cibrián Llanderal I

更新日期：2020-01-01 00:00:00

abstract：:The present study examined the effect of DS exposure on median nerve development in rats during prenatal life. Pregnant female rats were divided into three groups: a control group, a saline group and a DS group. Offspring of these animals were divided into 2 subgroups: 4 weeks old and 20 weeks old. Nerve samples were ...

journal_title：Folia neuropathologica

authors： Ayrancı E,Altunkaynak BZ,Aktaş A,Rağbetli MÇ,Kaplan S

更新日期：2013-01-01 00:00:00

abstract：:Paralytic tremor (pt), a hereditary neurological disorder of rabbits, is a recessive, X-linked point mutation in exon 2 of the plp gene, responsible for substitution of 38 His by Glu in the PLP molecule. Pt genotype is expressed in a range of phenotypes, distinguished by the severity of neurological symptoms. Variable...

journal_title：Folia neuropathologica

authors： Sypecka J,Domańska-Janik K

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:Ischemic stroke remains one of the top ten causes of death in children. There is evidence for the role of pro-inflammatory cytokines, such as IL-6 and the -174G>C promoter polymorphism of the IL-6 gene, in the occurrence and outcome of stroke in adults. The aim of the present study was to determine a possibl...

journal_title：Folia neuropathologica

authors： Balcerzyk A,Nowak M,Kopyta I,Emich-Widera E,Pilarska E,Pienczk-Ręcławowicz K,Kaciński M,Wendorff J,Zak I

更新日期：2012-01-01 00:00:00

abstract：:Cortical biopsies of 13 patients with clinical diagnosis of congenital hydrocephalus, Arnold-Chiari malformation and hydrocephalus, and postmeningitis hydrocephalus were examined by transmission electron microscopy to study the damage of endothelial cells, basement membrane, astrocytic end-feet layer, and perivascular...

journal_title：Folia neuropathologica

authors： Castejón OJ

更新日期：2009-01-01 00:00:00

abstract：:The effect of transient, global cerebral ischemia on the distribution of endothelin (ET) in blood-brain barrier (BBB) in CA1 area of hippocampus long-time after ischemia was estimated using post-embedding immunogold technique. ET-like immunoreactivity as a gold particles was localized in all compartments of the blood-...

journal_title：Folia neuropathologica

authors： Gajkowska B,Mossakowski MJ

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The efficacy of tempol and its acyl derivative tempol-C8 as retinoprotective agents was compared in a rat model of NMDA-induced retinal ganglion cell (RGC) damage. MATERIAL AND METHODS:Tempol or tempol-C8 in different doses was administered intraperitoneally to 6 weeks old (pre-adolescent) and 9-10 weeks ol...

journal_title：Folia neuropathologica

authors： Fiedorowicz M,Rejdak R,Schuettauf F,Wozniak M,Grieb P,Thaler S

更新日期：2014-01-01 00:00:00

abstract：:Early reviews identified over 20 risk factors associated with Alzheimer's disease (AD) including age, familial inheritance, exposure to aluminium, traumatic brain injury (TBI), and associated co-morbidities such as vascular disease and infection. In the light of recent evidence, this review reconsiders these risk fact...

journal_title：Folia neuropathologica

authors： A Armstrong R

更新日期：2019-01-01 00:00:00

abstract：:The authors present a rare case of C-6 vertebral involvement in a 12-year-old boy with histiocytosis X. The patient presented with limitation in movements of neck and upper extremities. Computed tomography (CT) and magnetic resonance (MRI) imaging were used in the preoperative workup. Surgery was performed via an ante...

journal_title：Folia neuropathologica

authors： Salehpour F,Tubbs RS,Zarrintan S,Meshkini A,Hadidchi S,Pourfathi H,Azhough R,Fakhrjou A,Goodrich JT,Khaki AA

更新日期：2007-01-01 00:00:00

abstract：:A neuropathological analysis of 172 cases of AIDS in adults was carried out, to determine the occurrence and nature of the opportunistic infections of the central nervous system (CNS). The material comprised 155 cases of men, and 17 women. Mean age of patients was 38 years. Collection under study originated from the p...

journal_title：Folia neuropathologica

authors： Zelman IB,Mossakowski MJ

更新日期：1998-01-01 00:00:00

abstract：:Prion-like transmission of protein aggregates or amyloid in several neurodegenerative diseases, such as Parkinson's disease, Huntington's disease and Alzheimer's disease, in addition to the transmissible spongiform encephalopathies (or prion diseases), has been proposed recently. This is a controversial idea and, in t...

journal_title：Folia neuropathologica

authors： Hope J,Kirby L

更新日期：2012-01-01 00:00:00

abstract：:The inflammatory process is a nonspecific complex, stereotype, coordinated response of tissues to injury. This process involves vascular permeability, active migration of blood cells, and passage of plasma constituents into the injurious tissue. The molecules that mediate the initial events of inflammation are the adh...

journal_title：Folia neuropathologica

authors： Maślińska D,Gajewski M

更新日期：1998-01-01 00:00:00

abstract：INTRODUCTION:Transsphenoidal surgery is the treatment of choice in Cushing's disease (CD), although even late recurrences occur in some patients. Low expression of O-6-methylguanine-DNA methyltransferase (MGMT) has been linked to a high risk of relapse in pituitary tumours, but the evidence for corticotroph adenomas is...

journal_title：Folia neuropathologica

authors： Witek P,Maksymowicz M,Szamotulska K,Piaścik A,Wojciechowska-Luźniak A,Stasiewicz A,Witek J,Zieliński G

更新日期：2020-01-01 00:00:00

abstract：:Epithelioid schwannomas occur predominantly in relation to peripheral nerves and are associated with histological and clinical malignancy. However, a variant of the epithelioid schwannoma involving cranial nerves is extremely rare. In this study we report three cases of epithelioid schwannomas originating from the aco...

journal_title：Folia neuropathologica

authors： Kroh H,Matyja E,Marchel A

更新日期：2000-01-01 00:00:00

abstract：:Inherited neurodegenerative disorders are debilitating diseases that occur across different species, such as the domestic dog (Canis lupus familiaris), and many are caused by mutations in the same genes as corresponding human conditions. In the present study, we report an inherited neurodegenerative condition, term...