In vivo micro-CT lung imaging via a computer-controlled intermittent iso-pressure breath hold (IIBH) technique.

abstract：:Radiochromic leuco crystal violet (LCV) micelle gel dosimeters are promising three-dimensional radiation dosimeters because of their spatial stability and suitability for optical readout. The effects of surfactant type and surfactant concentration on dose sensitivity of LCV micelle gels are tested, demonstrating that ...

journal_title：Physics in medicine and biology

authors： Nasr AT,Alexander K,Schreiner LJ,McAuley KB

更新日期：2015-06-21 00:00:00

abstract：:We have measured the bulk optical properties of healthy female breast tissues in vivo in the parallel plate, transmission geometry. Fifty-two volunteers were measured. Blood volume and blood oxygen saturation were derived from the optical property data using a novel method that employed a priori spectral information t...

journal_title：Physics in medicine and biology

authors： Durduran T,Choe R,Culver JP,Zubkov L,Holboke MJ,Giammarco J,Chance B,Yodh AG

更新日期：2002-08-21 00:00:00

abstract：:This paper investigates cone-beam tomography for a wide class of x-ray source trajectories called saddles. In particular, a mathematical analysis of the number of intersections between a saddle and an arbitrary plane is given. This analysis demonstrates that axially truncated cone-beam projections acquired along a sad...

journal_title：Physics in medicine and biology

authors： Pack JD,Noo F,Kudo H

更新日期：2004-06-07 00:00:00

abstract：BACKGROUND:During transcranial electrical stimulation (tES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), current density concentration around the electrode edges that is predicted by simplistic skin models does not match experimental observations of ...

journal_title：Physics in medicine and biology

authors： Khadka N,Bikson M

更新日期：2020-09-11 00:00:00

abstract：:Fluorescence molecular tomography (FMT) is widely used in preclinical oncology research. FMT is the only imaging technique able to provide 3D distribution of fluorescent probes within thick highly scattering media. However, its integration into clinical medicine has been hampered by its low spatial resolution caused b...

journal_title：Physics in medicine and biology

authors： Nouizi F,Kwong TC,Ruiz J,Cho J,Chan YW,Ikemura K,Erkol H,Sampathkumaran U,Gulsen G

更新日期：2019-01-22 00:00:00

abstract：:Stroke lesion volume is a key radiologic measurement in assessing prognosis of acute ischemic stroke (AIS) patients. The aim of this paper is to develop an automated segmentation method for accurately segmenting follow-up ischemic and hemorrhagic lesion from multislice non-contrast CT (NCCT) volumes of AIS patients. T...

journal_title：Physics in medicine and biology

authors： Kuang H,Menon BK,Qiu W

更新日期：2020-11-05 00:00:00

abstract：:A Monte Carlo computer program has been developed for the computation of integral radiation dose to the breast in xeromammography. The results are given in terms of the integral dose per unit area of the breast per unit incident exposure. The calculations have been made for monoenergetic incident photons and the resul...

journal_title：Physics in medicine and biology

authors： Dance DR

更新日期：1980-01-01 00:00:00

abstract：:The University of Washington (UW) Clinical Neutron Therapy System (CNTS) has been used to treat over 3300 patients. Treatment planning for these patients is currently performed using an MV x-ray model in Pinnacle® adapted to fit measurements of fast neutron output factors, wedge factors, depth-dose and lateral profile...

journal_title：Physics in medicine and biology

authors： Moffitt GB,Wootton LS,Hårdemark B,Sandison GA,Laramore GE,Parvathaneni U,Stewart RD

更新日期：2020-08-31 00:00:00

abstract：:Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provi...

journal_title：Physics in medicine and biology

authors： Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JG

更新日期：2000-10-01 00:00:00

abstract：:Determination of the cardiorespiratory phase of the heart has numerous applications during cardiac imaging. In this article we propose a novel view-angle independent near-real time cardiorespiratory motion gating and coronary sinus (CS) catheter tracking technique for x-ray fluoroscopy images that are used to guide ca...

journal_title：Physics in medicine and biology

authors： Panayiotou M,Rhode KS,King AP,Ma Y,Cooklin M,O'Neill M,Gill J,Rinaldi CA,Housden RJ

更新日期：2015-10-21 00:00:00

abstract：:The inadequate visibility of microcalcifications-small calcium deposits that cue radiologists to early stages of cancer-is a major limitation in current designs of dedicated breast computed tomography (bCT). This limitation has previously been attributed to the constituent components, spatial resolution, and utilized ...

journal_title：Physics in medicine and biology

authors： Ghazi P

更新日期：2020-12-04 00:00:00

abstract：:Many applications of electroporation, especially those utilizing electrofusion and in-vivo electroporation, involve cell environments that include close cell-to-cell proximity and a wide range of target cell size. It is important to understand how this kind of environment may alter optimum electroporation electrical p...

journal_title：Physics in medicine and biology

authors： Gaynor PT,Bodger PS

更新日期：2006-06-21 00:00:00

abstract：:While megavoltage cone-beam computed tomography (CBCT) using an electronic portal imaging device (EPID) provides many advantages over kilovoltage (kV) CBCT, clinical adoption is limited by its high doses. Multi-layer imager (MLI) EPIDs increase DQE(0) while maintaining high resolution. However, even well-designed, hig...

journal_title：Physics in medicine and biology

authors： Hu YH,Rottmann J,Fueglistaller R,Myronakis M,Wang A,Huber P,Shedlock D,Morf D,Baturin P,Star-Lack J,Berbeco R

更新日期：2018-01-30 00:00:00

abstract：:Although radionuclide therapy has been around for a long time, this modality of cancer treatment has been limited mainly to the use of [32P]-phosphate and [131I]-sodium iodide. The last few years, however, have seen an increased interest in this area due to new developments of radionuclides and carrier molecules that ...

journal_title：Physics in medicine and biology

authors： Zweit J

更新日期：1996-10-01 00:00:00

abstract：:A Monte Carlo computational model of a fluoroscopic imaging chain was used for deriving optimal technique factors for paediatric fluoroscopy. The optimal technique was defined as the one that minimizes the absorbed dose (or dose rate) in the patient with a constraint of constant image quality. Image quality was assess...

journal_title：Physics in medicine and biology

authors： Tapiovaara MJ,Sandborg M,Dance DR

更新日期：1999-02-01 00:00:00

abstract：:We have developed an impedance magnetocardiogram (IMCG) system to detect the change of magnetic field corresponding to changes in blood volume in the heart. A low magnetic field from the electrical activity of the human heart--the so-called magnetocardiogram (MCG)--can be simultaneously detected by using this system. ...

journal_title：Physics in medicine and biology

authors： Kandori A,Miyashita T,Suzuki D,Yokosawa K,Tsukada K

更新日期：2001-02-01 00:00:00

abstract：:Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of ...

journal_title：Physics in medicine and biology

authors： Modgil D,La Riviére PJ

更新日期：2010-12-07 00:00:00

abstract：:We propose a method to compensate for six degree-of-freedom rigid motion in helical CT of the head. The method is demonstrated in simulations and in helical scans performed on a 16-slice CT scanner. Scans of a Hoffman brain phantom were acquired while an optical motion tracking system recorded the motion of the bed an...

journal_title：Physics in medicine and biology

authors： Kim JH,Nuyts J,Kyme A,Kuncic Z,Fulton R

更新日期：2015-03-07 00:00:00

abstract：:Multileaf collimator (MLC) calibration and quality control is a time-consuming procedure typically involving the processing, scanning and analysis of films to measure leaf and collimator positions. Faster and more reliable calibration procedures are required for these tasks, especially with the introduction of intensi...

journal_title：Physics in medicine and biology

authors： Baker SJ,Budgell GJ,MacKay RI

更新日期：2005-04-07 00:00:00

abstract：:The purpose of this work is to develop and test a method to estimate the relative and absolute absorbed radiation dose from axial and spiral CT scans using a Monte Carlo approach. Initial testing was done in phantoms and preliminary results were obtained from a standard mathematical anthropomorphic model (MIRD V) and ...

journal_title：Physics in medicine and biology

authors： Jarry G,DeMarco JJ,Beifuss U,Cagnon CH,McNitt-Gray MF

更新日期：2003-08-21 00:00:00

abstract：:Large blood vessels can produce steep temperature gradients in heated tissues leading to inadequate tissue temperatures during hyperthermia. This paper utilizes a finite difference scheme to solve the basic equations of heat transfer and fluid flow to model blood vessel cooling. Unlike previous formulations, heat tran...

journal_title：Physics in medicine and biology

authors： Kolios MC,Sherar MD,Hunt JW

更新日期：1995-04-01 00:00:00

abstract：:Radiotherapy and particle therapy treatment planning require accurate knowledge of the electron density and elemental composition of the tissues in the beam path to predict the local dose deposition. We describe a method for the analysis of dual energy computed tomography (DECT) images that provides the electron densi...

journal_title：Physics in medicine and biology

authors： van Abbema JK,van Goethem MJ,Greuter MJ,van der Schaaf A,Brandenburg S,van der Graaf ER

更新日期：2015-05-07 00:00:00

abstract：:Simultaneous dual-radionuclide myocardial perfusion/innervation SPECT imaging can provide important information about the mismatch between scar tissue and denervated regions. The Siemens IQ-SPECT system developed for cardiac imaging uses a multifocal SMARTZOOM collimator to achieve a four-fold sensitivity for the card...

journal_title：Physics in medicine and biology

authors： Du Y,Bhattacharya M,Frey EC

更新日期：2014-06-07 00:00:00

abstract：:MRI-guided prostate biopsy in conventional closed-bore scanners requires transferring the patient outside the bore during needle insertion due to the constrained in-bore space, causing a safety hazard and limiting image feedback. To address this issue, we present our custom-made in-bore setup and software to support M...

journal_title：Physics in medicine and biology

authors： Tokuda J,Tuncali K,Iordachita I,Song SE,Fedorov A,Oguro S,Lasso A,Fennessy FM,Tempany CM,Hata N

更新日期：2012-09-21 00:00:00

abstract：:Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

journal_title：Physics in medicine and biology

authors： Wong JT,Molloi S

更新日期：2008-07-21 00:00:00

abstract：:In this paper, we present simulation studies for the second-generation MRI compatible SPECT system, MRC-SPECT-II, based on an inverted compound eye (ICE) gamma camera concept. The MRC-SPECT-II system consists of a total of 1536 independent micro-pinhole-camera-elements (MCEs) distributed in a ring with an inner diamet...

journal_title：Physics in medicine and biology

authors： Lai X,Meng LJ

更新日期：2018-02-12 00:00:00

abstract：:Models of the electrical properties of biological tissue have been the subject of many studies. These models have sought to explain aspects of the dielectric dispersion of tissue. This paper develops a mathematical model of the complex permittivity of tissue as a function of frequency f, in the range 10(4) < f < 10(7)...

journal_title：Physics in medicine and biology

authors： Smye SW,Evans CJ,Robinson MP,Sleeman BD

更新日期：2007-12-07 00:00:00

abstract：:Doxorubicin (Dox) is a well-established chemotherapeutic agent, however it has limited efficacy in treating brain malignancies due to the presence of the blood-brain barrier (BBB). Recent preclinical studies have demonstrated that focused ultrasound induced BBB disruption (BBBD) enables efficient delivery of Dox to th...

journal_title：Physics in medicine and biology

authors： Nhan T,Burgess A,Lilge L,Hynynen K

更新日期：2014-10-21 00:00:00

abstract：:Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be ...

journal_title：Physics in medicine and biology

authors： Flach B,Brehm M,Sawall S,Kachelrieß M

更新日期：2014-12-21 00:00:00

abstract：:The purpose of this study is to develop a new global mammographic image feature analysis based computer-aided detection (CAD) scheme and evaluate its performance in detecting positive screening mammography examinations. A dataset that includes images acquired from 1896 full-field digital mammography (FFDM) screening e...

journal_title：Physics in medicine and biology

authors： Tan M,Qian W,Pu J,Liu H,Zheng B

更新日期：2015-06-07 00:00:00