Circulating human C-reactive protein binds very low density lipoproteins.

abstract：:IgA nephropathy (IgAN) is the most common primary glomerulonephritis, with various pathological phenotypes. Our previous study suggested that aberrant glycosylation of serum IgA1 was associated with different pathological phenotypes of IgAN, and substantial evidence indicated that deglycosylated IgA1 had an increased ...

journal_title：Clinical and experimental immunology

authors： Yan Y,Xu LX,Zhang JJ,Zhang Y,Zhao MH

更新日期：2006-04-01 00:00:00

abstract：:The technical details of a fixation procedure with formaldehyde which was applied in a direct membrane immunofluorescence technique to mononuclear cells from normal human blood are described. After separation of the cells with Ficoll--Isopaque according to Böyum (1963) they were washed and fixed with 0 . 04% formaldeh...

journal_title：Clinical and experimental immunology

authors： Schuit HR,Hijmans W,Asma GE

更新日期：1980-09-01 00:00:00

abstract：:The 20-kD homologous restriction factor (HRF20), which is identical to CD59, is a membrane-associated protein which inhibits the reaction of C9 to form membrane attack complex (MAC) of homologous complements. In various human glomerular diseases deposition of complement components is frequently seen and MAC is reporte...

journal_title：Clinical and experimental immunology

authors： Tamai H,Matsuo S,Fukatsu A,Nishikawa K,Sakamoto N,Yoshioka K,Okada N,Okada H

更新日期：1991-05-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an idiopathic systemic autoimmune disease. It is characterized by a triad of hallmarks: immune dysfunction, fibrosis and vasculopathy. Immune dysfunction in SSc is characterized by the activation and recruitment of immune cells and the production of autoantibodies and cytokines. How immune ...

journal_title：Clinical and experimental immunology

authors： Brown M,O'Reilly S

更新日期：2019-03-01 00:00:00

abstract：:Circulating immune complexes (CIC) were detected by a solid-phase radioassay in 34% of fifty-three insulin-dependent diabetics (IDD) as compared to 18% of forty-five non-insulin-dependent diabetics (NIDD) and 14% of 173 control subjects. In control subjects, the prevalence of CIC increased with age and was higher in m...

journal_title：Clinical and experimental immunology

authors： Delespesse G,Gausset P,Sarfati M,Dubi-Rucquoy M,Debisschop MJ,van Haelst L

更新日期：1980-04-01 00:00:00

abstract：:This study was performed to determine whether or not IL-18, formerly called IFN-gamma-inducing factor, is involved in the pathogeneses of allergic disorders. Peripheral blood mononuclear cells (PBMC) were obtained from patients with allergic bronchial asthma (BA), patients with atopic dermatitis (AD) and controls who ...

journal_title：Clinical and experimental immunology

authors： El-Mezzein RE,Matsumoto T,Nomiyama H,Miike T

更新日期：2001-11-01 00:00:00

abstract：:Whether differences in foetoplacental weight and post-implantation mortality in rodents are secondary to heterosis and inbreeding depression or antigenic differences between mother and foetus has been a continuing controversy. To determine whether non-specific depression or stimulation of the maternal immune system af...

journal_title：Clinical and experimental immunology

authors： Scott JR,Feldbush TL,Covault JM

更新日期：1977-12-01 00:00:00

abstract：:In view of its potent inhibitory capacity on immune cells in culture, we wished to determine the ability of transforming growth factor (TGF) beta 1 to down-regulate immune responses in vivo. Preliminary experiments suggested that, at the doses used, systemic injection of soluble TGF beta 1 could not affect bacterial-i...

journal_title：Clinical and experimental immunology

authors： Strassmann G,Bertolini DR,Eidelman O

更新日期：1991-12-01 00:00:00

abstract：:Anti-cardiolipin antibodies, oxidatively modified low-density lipoproteins (oxLDL) and circulating immune complexes are humoral factors that have been linked to vascular damage. To analyse their possible role in the vascular complications in type 1 diabetes mellitus, we investigated patients with and without vascular ...

journal_title：Clinical and experimental immunology

authors： Ahmed E,Nityanand S,Mustafa A,Brismar K,Lefvert AK

更新日期：1999-02-01 00:00:00

abstract：:Thirty-three patients with chronic hepatitis C/non-A, non-B were included in a randomized controlled study of interferon-alpha 2b (IFN-alpha 2b) treatment, 3 x 10(6) U three times weekly for 36 weeks. Using an immunoperoxidase technique, frozen liver biopsy specimens were examined with MoAbs for the presence of T help...

journal_title：Clinical and experimental immunology

authors： Wejstål R,Norkrans G,Weiland O,Schvarcz R,Fuchs D,Wachter H,Fryden A,Glaumann H

更新日期：1992-03-01 00:00:00

abstract：:Native type II collagens of rat, chick, bovine, human and murine origin have been used for immunization of male and female DBA/1 mice of different ages. The four heterologous collagens were able to induce arthritis in both male and female mice although the incidence of arthritis was higher in males. The onset of arthr...

journal_title：Clinical and experimental immunology

authors： Holmdahl R,Jansson L,Gullberg D,Rubin K,Forsberg PO,Klareskog L

更新日期：1985-12-01 00:00:00

abstract：:The lymphocyte activating properties of a membrane proteoglycan (MPG) extracted from a mutant non-encapsulated strain of Klebsiella pneumoniae (Kp) (biotype a I-145) were investigated. Kp MPG induced a strong proliferative response of BALB/c spleen cells and Peyer's patches cells. Thymidine incorporation was dose-rela...

journal_title：Clinical and experimental immunology

authors： Millet I,Lafont S,de Fraissinette A,Jeannin M,Revillard JP,Normier G,Dussourd d'Hinterland L

更新日期：1987-10-01 00:00:00

abstract：:T cells implicated in chronic inflammatory diseases such as RA respond weakly when stimulated in vitro with mitogen or antigen. The mechanism behind this hyporesponsiveness is unclear, but a depressed expression of the T cell receptor (TCR)-associated CD3zeta chain has been suggested. In the present work we describe a...

journal_title：Clinical and experimental immunology

authors： Berg L,Rönnelid J,Klareskog L,Bucht A

更新日期：2000-04-01 00:00:00

abstract：:Dipeptidyl peptidase IV (DPIV), a T cell enzyme, has been implicated in the regulation of lymphocyte proliferation in response to lectins and allogeneic cells. A sensitive fluorimetric assay has been established for the enzyme and used to investigate DPIV activity, kinetics and the subcellular localization in lymphocy...

journal_title：Clinical and experimental immunology

authors： Harland C,Shah T,Webster AD,Peters TJ

更新日期：1988-11-01 00:00:00

abstract：:Thyroid autoantigens require internalization and processing by antigen-presenting cells to induce immune responses. Besides pinocytosis, antigen uptake can be receptor-mediated. The mannose receptor (ManR) has a cysteine rich domain (CR) and eight carbohydrate recognition domains (CRD) that bind glycosylated proteins....

journal_title：Clinical and experimental immunology

authors： Chazenbalk GD,Pichurin PN,Guo J,Rapoport B,McLachlan SM

更新日期：2005-02-01 00:00:00

abstract：:We have previously demonstrated that immune platelet destruction observed in an AIDS-free HIV-infected patient was associated with the presence of a cross-reactive antibody recognizing both HIV-glycoprotein (gp)120 and platelet gpIIIa (CD61). We have now investigated the presence of such antibodies in other HIV-infect...

journal_title：Clinical and experimental immunology

authors： Bettaieb A,Oksenhendler E,Duedari N,Bierling P

更新日期：1996-01-01 00:00:00

abstract：:The kinetics and effects of in vivo spontaneous apoptosis and activation-induced cell death (AICD) upon CD4+ and CD8+ lymphocyte subsets and CD4 naive cell numbers were studied in HIV+ subjects with CD4 pretreatment values > 200/mm3, who were subsequently treated for 48 weeks with HAART alone or in combination with si...

journal_title：Clinical and experimental immunology

authors： Caggiari L,Zanussi S,Bortolin MT,D'andrea M,Nasti G,Simonelli C,Tirelli U,De Paoli P

更新日期：2000-04-01 00:00:00

abstract：:Cyclosporin A (Cy A) enhances immunoglobulin (Ig) production by EB virus stimulated peripheral blood lymphocytes from normal subjects with prior immunity to EB virus. In 11 normal adults, this enhancement of Ig production correlated with T cell-mediated cytotoxic regression. Cultures from normal healthy adults without...

journal_title：Clinical and experimental immunology

authors： Pereira RS,Gear AJ,Doré CJ,Webster AD

更新日期：1983-07-01 00:00:00

abstract：:Serum from 98 Thai adults infected with Plasmodium falciparum were examined for the presence of autoantibodies. Malarial containing antibodies sera were also revealed positive for anti-nuclear antibodies with fluorescence speckled pattern, anti-smooth muscle antibodies, anti-mitochondria antibodies and rheumatoid fact...

journal_title：Clinical and experimental immunology

authors： Boonpucknavig S,Ekapanyakul G

更新日期：1984-10-01 00:00:00

abstract：:Children receiving anti-leukaemic therapy often become susceptible to severe herpesvirus infection. To investigate specific immunity to herpes simplex virus (HSV) in patients with acute lymphoblastic leukaemia (ALL), in first remission and receiving maintenance chemotherapy, we measured their HSV specific T responder ...

journal_title：Clinical and experimental immunology

authors： Tellez PA,Odom L,Hayward AR

更新日期：1985-12-01 00:00:00

abstract：:The concept that during an immune challenge the release of glucocorticoids (GC) provides feedback inhibition on evolving immune responses has been drawn primarily from studies of autoimmune and/or inflammatory processes in animal models. The epidemic form of haemolytic uraemic syndrome (HUS) occurs secondary to infect...

journal_title：Clinical and experimental immunology

authors： Gómez SA,Fernández GC,Vanzulli S,Dran G,Rubel C,Berki T,Isturiz MA,Palermo MS

更新日期：2003-02-01 00:00:00

abstract：:The intestinal population of gamma delta T cell receptor (TCR)-bearing cells was characterized with regard to V delta and V gamma subtype expression. For this purpose, we utilized V gene-specific PCR of mRNA prepared from intestinal biopsies. Predominant expression of the V delta 1 subtype was demonstrated in the smal...

journal_title：Clinical and experimental immunology

authors： Bucht A,Söderström K,Esin S,Grunewald J,Hagelberg S,Magnusson I,Wigzell H,Grönberg A,Kiessling R

更新日期：1995-01-01 00:00:00

abstract：:The effects of surgery on the immune response (as measured by a variety of parameters) were examined in patients undergoing transurethral resection of the prostate (TURP) for benign disease. Two groups were assessed, one having the procedure performed under a general anaesthetic and the other under a spinal anaestheti...

journal_title：Clinical and experimental immunology

authors： Whelan P,Morris PJ

更新日期：1982-06-01 00:00:00

abstract：:We report here the characterization and fine specificity of a human monoclonal IgM lambda reacting with double stranded DNA. The purified IgM and its Fab fragment bind to DNA in the Farr or Crithidia lucilae assays as well as in an immunoenzymatic test. In the latter case, binding was inhibited by native DNA, by DNA a...

journal_title：Clinical and experimental immunology

authors： Fermand JP,Danon F,Brouet JC

更新日期：1985-02-01 00:00:00

abstract：:In vitro immunoglobulin (Ig) synthesis was evaluated in three young men having immunodeficiency with hyper-IgM. Patient and normal T and B cells were separated and cultured in various combinations. 35S-methionine incorporation into Ig was measured using immunoprecipitation, and Ig classes were determined by SDS-polyac...

journal_title：Clinical and experimental immunology

authors： Krantman HJ,Stiehm ER,Stevens RH,Saxon A,Seeger RC

更新日期：1980-04-01 00:00:00

abstract：:Young rats were not able to expel adult N. brasiliensis infections even when the worms were damaged by antibodies and the young rats were given all the cellular components (sensitized lymphocytes and bone marrow cells) shown to be necessary for the expulsion of antibody-damaged worms from adult rats. In contrast, most...

journal_title：Clinical and experimental immunology

authors： Love RJ,Ogilvie BM

更新日期：1975-07-01 00:00:00

abstract：:Previous studies of an experimental human immunoglobulin preparation for intravenous use, containing normal pooled IgM (IVIgM), have shown its beneficial therapeutic effect in experimental autoimmune diseases. The mechanisms of its immunomodulatory activity remain however, poorly understood. In the experiments reporte...

journal_title：Clinical and experimental immunology

authors： Vassilev T,Mihaylova N,Voynova E,Nikolova M,Kazatchkine M,Kaveri S

更新日期：2006-07-01 00:00:00

abstract：:Eight genetically different strains of mice were compared regarding the dissemination of Paracoccidioides brasiliensis to the lungs, liver and omentum/pancreas, DTH responses and specific antibody production at 16 weeks after intraperitoneal infection with Pb18, a virulent P. brasiliensis isolate. The degree of dissem...

journal_title：Clinical and experimental immunology

authors： Singer-Vermes LM,Sakamoto TN,Vaz CA,Calich VL

更新日期：1995-07-01 00:00:00

abstract：:Many cellular stresses and inflammatory stimuli can activate p38 mitogen-activated protein kinase (MAPK), a serine/threonine kinase in the MAPK family. The different stimuli act via different receptors or signalling pathways to induce phosphorylation of the cytosolic protein p47(phox), one subunit of the nicotinamide ...

journal_title：Clinical and experimental immunology

authors： Lu HW,He GN,Ma H,Wang JK

更新日期：2010-06-01 00:00:00

abstract：:Human peripheral blood lymphocytes injected intradermally into X-ray immunosuppressed mice were tested for angiogenesis-inducing capacity. Both T and B lymphocytes evoked angiogenesis of the same intensity. The total T cell population was fractionated into three subpopulations on the basis of their different affinitie...

journal_title：Clinical and experimental immunology

authors： Kamiński MJ,Nowacyk M,Skopińska-Rozewska E,Kamińska G,Bem W

更新日期：1981-11-01 00:00:00