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Sulfate transport in brush border membrane vesicles prepared from human placental syncytiotrophoblast.

Abstract：

:Isolated brush-border membrane vesicles prepared from human placenta are known to transport amino acids via a Na+-dependent mechanism akin to that found in gut and kidney vesicle preparations. We studied sulfate transport in placental vesicles and failed to identify any Na+-dependent uptake mechanism. Rather, uptake is a non-electrogenic process that is trans-stimulated by outwardly directed anion flux which is independent of cation. If anion exchange is tightly coupled in vivo, the net transfer of sulfate from mother to the growing fetus may be driven by the continuous flux of bicarbonate in the opposite direction.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Cole DE

doi

10.1016/0006-291x(84)90402-9

subject

Has Abstract

pub_date

1984-08-30 00:00:00

pages

223-9

issue

1

eissn

0006-291X

issn

1090-2104

pii

0006-291X(84)90402-9

journal_volume

123

pub_type

杂志文章

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