A DNA-binding protein from E. coli isolation, characterization and its relationship with proteins H1 and B1.

abstract：:Leishmania donovani is an obligate intracellular parasite that infects macrophages of the vertebrate host resulting in visceral leishmaniasis in humans, a major public health problem worldwide. The molecular mechanisms involved in internalization of Leishmania are still poorly characterized. We report here that choles...

journal_title：Biochemical and biophysical research communications

authors： Tewary P,Veena K,Pucadyil TJ,Chattopadhyay A,Madhubala R

更新日期：2006-01-13 00:00:00

abstract：:Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that ...

journal_title：Biochemical and biophysical research communications

authors： Fu J,Xu X,Kang L,Zhou L,Wang S,Lu J,Cheng L,Fan Z,Yuan B,Tian P,Zheng X,Yu C,Ye Q,Lv Z

更新日期：2014-03-07 00:00:00

abstract：:A cDNA containing the entire coding sequence for the subunit protein of rat liver class theta glutathione S-transferase (GST) Yrs-Yrs was isolated from a rat liver lambda gt11 cDNA library. The cDNA, designated GST theta-1, consisted of 1,258 bp which had an open reading frame of 732 bp encoding a polypeptide of 244 a...

journal_title：Biochemical and biophysical research communications

authors： Ogura K,Nishiyama T,Okada T,Kajital J,Narihata H,Watabe T,Hiratsuka A,Watabe T

更新日期：1991-12-31 00:00:00

abstract：:The diagnostic significance of phosphoglycerate mutase (PGM) B-type isozyme activity capable of being inducible under hypoxia at the gene level as a serum marker for cerebral stroke was investigated. The normal level (mean +/- 2 SD) in human serum was determined to be 38 +/- 18 units/L. Within 2 h after the onset of c...

journal_title：Biochemical and biophysical research communications

authors： Hayashi T,Matuo Y

更新日期：2001-10-05 00:00:00

abstract：:Peptides of the protein transduction domain (PTD) mediate the introduction of passenger proteins into cells in vitro and in vivo, where the domains are positively charged. This unusual ability can be exploited for medical applications in protein therapeutics. Chondrocytes are embedded in a dense extracellular matrix, ...

journal_title：Biochemical and biophysical research communications

authors： Ozaki D,Sudo K,Asoh S,Yamagata K,Ito H,Ohta S

更新日期：2004-01-16 00:00:00

abstract：:A cDNA for tetrameric carbonyl reductase was cloned from a pig lung cDNA library. The cDNA had an open reading frame encoding a protein of 244 amino acid residues with a predicted monomer molecular weight of 25,985. The authenticity of the cDNA was confirmed by a perfect match of 80 amino acids determined from sequenc...

journal_title：Biochemical and biophysical research communications

authors： Nakanishi M,Deyashiki Y,Nakayama T,Sato K,Hara A

更新日期：1993-08-16 00:00:00

abstract：:1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3) increases the binding of transforming growth factor beta1(TGF beta1) via TGF beta receptors to the surface of human osteoblasts. The increase in TGF beta receptors induced by 1alpha,25(OH)2D3 is dependent on increases in TGF beta secretion induced by 1alpha,25(OH)2D3, s...

journal_title：Biochemical and biophysical research communications

authors： Nagel D,Kumar R

更新日期：2002-02-08 00:00:00

abstract：:It is now well established that PA is a potent biological response modifier, showing simultaneously antitumor, antitoxic, anticarcinogenic, antifungal, antiparasitic and immunomodulatory properties. Since PA is a foreign protein, it is quite logical to assume that it may be cleaved into smaller peptide fragments in vi...

journal_title：Biochemical and biophysical research communications

authors： Sinha P,Sengupta J,Ray PK

更新日期：1999-04-29 00:00:00

abstract：:Oleanolic acid (OA), a pentacyclic triterpene acid, is reported to have antitumor activities; however, the mechanism underlying its antitumorigenic effects is poorly understood. To further determine the mechanism of OA, we investigated the effects of OA on the release of nitric oxide (NO) and tumor necrosis factor-alp...

journal_title：Biochemical and biophysical research communications

authors： Choi CY,You HJ,Jeong HG

更新日期：2001-10-19 00:00:00

abstract：:We have used site-directed mutagenesis to investigate the requirement of cysteine residues in the extracellular domains of the human VIP 1 receptor for binding VIP. Cys37, Cys50, Cys63, Cys72, Cys86, Cys105 and Cys122 (N-terminal extracellular domain), Cys208 and Cys215 (second extracellular loop) and Cys288 (third ex...

journal_title：Biochemical and biophysical research communications

authors： Gaudin P,Couvineau A,Maoret JJ,Rouyer-Fessard C,Laburthe M

更新日期：1995-06-26 00:00:00

abstract：:Cancer stem cells (CSCs) are a small population of cells with stem cell-like properties found in tumors. CSCs are closely associated with tumor heterogeneity, which influences tumor progress, metastasis, and drug resistance. Here, we propose a concept to enhance efficacy of cancer therapy through CSC reprogramming int...

journal_title：Biochemical and biophysical research communications

authors： Lee KS,Choi JS,Cho YW

更新日期：2019-05-07 00:00:00

abstract：:Two novel neuropeptides, urechistachykinin I (H-Leu-Arg-Gln-Ser-Gln-Phe-Val-Gly-Ser-Arg-NH2) and urechistachykinin II (H-Ala-Ala-Gly-Met-Gly-Phe-Phe-Gly-Ala-Arg-NH2), were isolated from the ventral nerve cords of the echiuroid worm, Urechis unicinctus. These peptides showed a contractile action on the inner circular b...

journal_title：Biochemical and biophysical research communications

authors： Ikeda T,Minakata H,Nomoto K,Kubota I,Muneoka Y

更新日期：1993-04-15 00:00:00

abstract：:We have investigated the involvement of P-glycoprotein (P-gp)/caveolin-1 interaction in the regulation of brain endothelial cells (EC) migration and tubulogenesis. P-gp overexpression in MDCK-MDR cells was correlated with enhanced cell migration whereas treatment with P-gp inhibitors CsA or PSC833 reduced it. Transfec...

journal_title：Biochemical and biophysical research communications

authors： Barakat S,Turcotte S,Demeule M,Lachambre MP,Régina A,Baggetto LG,Béliveau R

更新日期：2008-08-01 00:00:00

abstract：:Dendritic cells (DCs) play an important role in vertebrate immunity, but little is known of the molecular events associated with their development from bone marrow (BM). This report describes induction of a signature protein marking BM commitment to DCs. Using a standard procedure, DCs were generated from BM by cultiv...

journal_title：Biochemical and biophysical research communications

authors： Al-Shaibi N,Ghosh SK

更新日期：2004-08-13 00:00:00

abstract：:Tissue transglutaminase (TGase 2) has been reported to have multiple functions in addition to its function as a biological adhesive. To identify its roles, we investigated the effects of TGase 2 on gelatinase activity. The MMP-9 activity of certain cell lines was significantly inhibited with retinoic acid treatment, a...

journal_title：Biochemical and biophysical research communications

authors： Ahn JS,Kim MK,Hahn JH,Park JH,Park KH,Cho BR,Park SB,Kim DJ

更新日期：2008-11-28 00:00:00

abstract：:We have previously shown that C-CAM1 cell adhesion molecule can suppress the growth of prostate cancer cells in vivo. In this study, we determined the minimal domain of C-CAM1 that is required for its tumor-suppressive activity. DU145 prostate cancer cells were infected with recombinant adenoviruses containing various...

journal_title：Biochemical and biophysical research communications

authors： Estrera VT,Luo W,Phan D,Earley K,Hixson DC,Lin SH

更新日期：1999-10-05 00:00:00

abstract：:CHFR has been implicated as a tumor suppressor in a multitude of cancers. It was originally identified as a major component of the antephase checkpoint. Recently, CHFR was reported to interact with MAD2, an important component of the spindle assembly checkpoint, where CHFR knockdown resulted in mislocalization of MAD2...

journal_title：Biochemical and biophysical research communications

authors： Keller JA,Petty EM

更新日期：2011-06-10 00:00:00

abstract：:In order to study the role of phosphatidylinositol-3-kinase (PI3K) in insulin action, we employed a specific inhibitor of PI3K, LY294002, and measured five biological functions of insulin in mouse 3T3 fibroblasts overexpressing human insulin receptors. LY294002 had no effect on tyrosine phosphorylation of both the ins...

journal_title：Biochemical and biophysical research communications

authors： Sanchez-Margálet V,Goldfine ID,Vlahos CJ,Sung CK

更新日期：1994-10-28 00:00:00

abstract：:Despite the mitochondria ubiquitous nature many of their components display divergences in their expression profile across different tissues. Using the bioinformatics-approach of guilt by association (GBA) we exploited these variations to predict the function of two so far poorly annotated genes: Coiled-coil-helix-coi...

journal_title：Biochemical and biophysical research communications

authors： Martherus RS,Sluiter W,Timmer ED,VanHerle SJ,Smeets HJ,Ayoubi TA

更新日期：2010-11-12 00:00:00

abstract：:The dopamine receptor D4 (DRD4) has received increasing research attention in behavioral science, psychiatry, and psychopharmacology. However, the number of available genetic markers for primates is still insufficient. We identified a novel variation/polymorphism in the second intron of DRD4 in humans based on the sur...

journal_title：Biochemical and biophysical research communications

authors： Shimada MK,Inoue-Murayama M,Ueda Y,Maejima M,Murayama Y,Takenaka O,Hayasaka I,Ito S

更新日期：2004-04-16 00:00:00

abstract：:The use of dry Bacillus subtilis spores as a biological dosimeter for the monitoring of solar UV-B (290-330 nm) radiation was described. Our field tests had supported the utility of this dosimeter as a reproducible and reliable sunlight dosimeter. ...

journal_title：Biochemical and biophysical research communications

authors： Wang TC

更新日期：1991-05-31 00:00:00

abstract：:Recent studies revealed dramatic changes in circadian clock genes' expression during the perinatal period. In this study, we characterized DNA methylation for three clock genes mPer1, mPer2, and mCry1 at their selected promoter regions during development. Results for the suprachiasmatic nucleus (SCN) and liver (at emb...

journal_title：Biochemical and biophysical research communications

authors： Ji Y,Qin Y,Shu H,Li X

更新日期：2010-01-22 00:00:00

abstract：:A procedure was developed for real-time measurement of the interaction between an archaeal TATA-binding protein (TBP) with stress-gene promoters from the archaeon Methanosarcina mazeii using surface plasmon resonance (SPR), the BIACORE 3000 equipment, and the SA (streptavidin) Sensor Chip. Measurements were based on t...

journal_title：Biochemical and biophysical research communications

authors： Conway de Macario E,Rudofsky UH,Macario AJ

更新日期：2002-11-15 00:00:00

abstract：:Cancer cell molecular mimicry of stem cells (SC) follows with enhanced proliferative and renewal capacities. In support, numerous mediators of SC self-renewal have been evinced to exhibit oncogenic potential. More and more researches showed that the embryonic stem cell self-renewal genes express in various cancer cell...

journal_title：Biochemical and biophysical research communications

authors： Deng L,Xiang X,Yang F,Xiao D,Liu K,Chen Z,Zhang R,Feng G

更新日期：2017-08-19 00:00:00

abstract：:Ligands of the glial cell line-derived neurotrophic factors (GDNF)-family are trophic factors for the development and survival of multiple cell types, however their effects on non-neuronal stem cells are unknown. We examined the action of neurturin on a candidate stem cell population isolated from adult skeletal muscl...

journal_title：Biochemical and biophysical research communications

authors： Vourc'h P,Lacar B,Mignon L,Lucas PA,Young HE,Chesselet MF

更新日期：2005-06-24 00:00:00

abstract：:Activation of the transcription factor NF-kappaB results in protection against apoptosis, and the chemotherapeutic agent 5-Fluorouracil (5-FU) exerts its cytotoxic effect through the induction of apoptosis. Thus, we examined whether 5-FU could induce apoptosis through the suppression of NF-kappaB activity. We found th...

journal_title：Biochemical and biophysical research communications

authors： Aota K,Azuma M,Yamashita T,Tamatani T,Motegi K,Ishimaru N,Hayashi Y,Sato M

更新日期：2000-07-14 00:00:00

abstract：:The characterization of a 20 kilodalton (20 kD) variant of rat growth hormone is reported. The 20 kD variant from rat pituitary gland extracts was identified on Western immunoblots of polyacrylamide gels. It was also shown that pituitary tissue maintained in culture secretes the 20 kD form. A rat growth hormone cDNA f...

journal_title：Biochemical and biophysical research communications

authors： Howland DS,Farrington MA,Taylor WD,Hymer WC

更新日期：1987-09-15 00:00:00

abstract：:The immunosuppressant FK506 inhibits thymocyte positive selection. Calcineurin, a FK506-sensitive Ca2+/calmodulin-dependent protein phosphatase, is presumed to be involved in this event without direct evidence. We have previously shown that moderate stimulation of CD4(+)CD8(+) thymocytes with a combination of the calc...

journal_title：Biochemical and biophysical research communications

authors： Kuwata T,Asada A,Ohoka Y,Mukai M,Miyaike M,Iwata M

更新日期：1998-06-18 00:00:00

abstract：:When human peripheral monocytes and rabbit peritoneal macrophages were incubated with hyaluronic acid, the media were found to contain interleukin-1 (IL-1) activity and to stimulate collagenase production by rabbit fibroblasts. A digestion of hyaluronic acid by testicular hyaluronidase decreased the IL-1 inducing acti...

journal_title：Biochemical and biophysical research communications

authors： Hiro D,Ito A,Matsuta K,Mori Y

更新日期：1986-10-30 00:00:00

abstract：:Murine interferon-alpha 1 and murine interferon-alpha 4 share 80% of their amino acids, yet the proteins differ considerably in their ability to protect mouse or hamster cells against viral infection. With the aim of localizing areas within these proteins which influence the biological response we have constructed hyb...

journal_title：Biochemical and biophysical research communications

authors： Zwarthoff EC,Gennissen A,Bosveld IJ,Trapman J,van Heuvel M

更新日期：1987-08-31 00:00:00