当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Molecular cloning and amino acid sequencing of rat liver class theta glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols.

Molecular cloning and amino acid sequencing of rat liver class theta glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols.

Abstract：

:A cDNA containing the entire coding sequence for the subunit protein of rat liver class theta glutathione S-transferase (GST) Yrs-Yrs was isolated from a rat liver lambda gt11 cDNA library. The cDNA, designated GST theta-1, consisted of 1,258 bp which had an open reading frame of 732 bp encoding a polypeptide of 244 amino acid (AA) residues, including the leading AA Met to be removed on expression. The authenticity of the cDNA structure was supported by matching its deduced AA sequence with N-termini of Yrs and peptides obtained thereof by tryptic digestion as well as by CNBr cleavage. The deduced AA sequence of the subunit Yrs (M.W. 27,311) had only a weak homology (19-23%) with those of rat liver classes alpha, mu, and pi GST isozymes. Thus, the first evidence for the molecular cloning of the class theta GST was provided.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Ogura K,Nishiyama T,Okada T,Kajital J,Narihata H,Watabe T,Hiratsuka A,Watabe T

doi

10.1016/0006-291x(91)92079-y

subject

Has Abstract

pub_date

1991-12-31 00:00:00

pages

1294-300

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(91)92079-Y

journal_volume

181

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Comparative gene expression in the symbiotic and aposymbiotic Aiptasia pulchella by expressed sequence tag analysis.

    abstract：:Intracellular symbiotic relationships are prevalent between cnidarians, such as corals and sea anemones, and the photosynthetic dinoflagellate symbionts. However, there is little understanding about how the genes express when the symbiotic relationship is set up. To characterize genes involved in this association, the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.03.191

    authors： Kuo J,Chen MC,Lin CH,Fang LS

    更新日期：2004-05-21 00:00:00

  • Nerve growth factor mRNA in brain: localization by in situ hybridization.

    abstract：:Nerve Growth Factor is a 118 amino acid polypeptide that plays an important role in the differentiation and survival of neurons. The recent discovery that a mRNA that encodes beta Nerve Growth Factor is present in brain suggests that the Nerve Growth Factor gene may not only regulate gene expression of peripheral but ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(86)80569-1

    authors： Rennert PD,Heinrich G

    更新日期：1986-07-31 00:00:00

  • Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor.

    abstract：:A cDNA clone of an alpha subunit of the human GABA-A receptor has been isolated. The human clone (pCLL800) contains 1055 nucleotides in an open reading frame and 260 nucleotides in the 5' non-coding region. The 351 amino acid sequence of this human alpha subunit shows 97% homology with its bovine counterpart. Hybridiz...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80949-5

    authors： Garrett KM,Duman RS,Saito N,Blume AJ,Vitek MP,Tallman JF

    更新日期：1988-10-31 00:00:00

  • CPuORF correlates with miRNA responsive elements on protein evolutionary rates.

    abstract：:miRNA is increasingly being recognized as a key regulator of metabolism in animals. A wealth of evidence has suggested that miRNA mainly binds 3' UTR of mRNA and modulates the cell activities via repressing the mRNA translation. However, as the translation initiates at 5' UTR, cis elements like upstream open reading f...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.08.050

    authors： Hu W,Wang T,Yang Y,Zheng S

    更新日期：2014-09-12 00:00:00

  • Of mice and men: from early NMR studies of the heart to physiological genomics.

    abstract：:Just before I became an editor of Biochemical and Biophysical Research Communications in 1977 we published our first paper in this same journal on the study of tiny perfused rat hearts by (31)P NMR. In this article I trace the development of this in vivo NMR approach from the study of small rat and mouse hearts to hum...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1006/bbrc.1999.1890

    authors： Radda GK

    更新日期：1999-12-29 00:00:00

  • AMPK activation by pterostilbene contributes to suppression of hepatic gluconeogenic gene expression and glucose production in H4IIE cells.

    abstract：:Pterostilbene, a bioactive component of blueberries and grapes, shows structural similarity to resveratrol, and exhibits antioxidant, anti-inflammatory, anti-cancer, hypoglycemic, and cholesterol lowering effects. Recent evidence indicates that pterostilbene is an agonist of the nuclear receptor, peroxisome proliferat...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.03.035

    authors： Ren G,Rimando AM,Mathews ST

    更新日期：2018-04-06 00:00:00

  • Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa.

    abstract：:Recent studies from our laboratory demonstrated that Egr-1 is upregulated in the rat duodenal mucosa during cysteamine-induced duodenal ulceration and that antisense egr-1 oligonucleotide aggravates the duodenal ulcers. This study was aimed to determine the effects of cysteamine on redox-sensitive Egr-1 transcriptiona...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.08.092

    authors： Khomenko T,Deng X,Jadus MR,Szabo S

    更新日期：2003-10-03 00:00:00

  • Neddylation promotes protein translocation between the cytoplasm and nucleus.

    abstract：:Neddylation is an ubiquitin-like modification of proteins that affects the activity, stability and protein-protein interaction of its substrates. Apart from its role as a promoter for Cullin ring E3 ligase to positively regulate the ubiquitylation process, other functional studies about neddylation are still lacking. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.07.012

    authors： Li S,Fang W,Cui Y,Shi H,Chen J,Li L,Zhang L,Zhang X

    更新日期：2020-09-03 00:00:00

  • Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells.

    abstract：:Wnt/beta-catenin signaling plays an important role not only in cancer, but also in cancer stem cells. In this study, we found that beta-catenin and OCT-4 was highly expressed in cisplatin (DDP) selected A549 cells. Stimulating A549 cells with lithium chloride (LiCl) resulted in accumulation of beta-catenin and up-regu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.01.028

    authors： Teng Y,Wang X,Wang Y,Ma D

    更新日期：2010-02-12 00:00:00

  • Ethanol increases apolipoprotein B mRNA editing in rat primary hepatocytes and McArdle cells.

    abstract：:Apolipoprotein B (apoB) mRNA editing involves a site-specific cytidine to uridine transition catalyzed by the cytidine deaminase, APOBEC-1, in the context of and regulated by a multi-protein-containing editosome. ApoB mRNA editing in vivo is subject to tissue specific, developmental and metabolic regulation. We demons...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.9647

    authors： Van Mater D,Sowden MP,Cianci J,Sparks JD,Sparks CE,Ballatori N,Smith HC

    更新日期：1998-11-18 00:00:00

  • Demonstration of a 1-3 disulfide bond in a synthetic nonapeptide derived from the signal sequence and N-terminus of human gamma-interferon.

    abstract：:The nonapeptide Cys-Tyr-Cys-Gln-Asp-Pro-Tyr-Val-Lys was prepared by solid-phase peptide synthesis under oxidizing conditions. Fast atom bombardment mass spectrometric analysis of the untreated molecule produced an ion consistent with a structure involving an intramolecular disulfide bond between Cys(1) and Cys(3). Mas...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80325-5

    authors： Pramanik B,Tsarbopoulos A,Labdon JE,Czarniecki M,Nagabhushan TL,Trotta PP

    更新日期：1988-12-15 00:00:00

  • Functional synergism of Human Defensin 5 and Human Defensin 6.

    abstract：:The gut epithelium is critically involved in maintaining intestinal immune homeostasis. Acting as a physical barrier, it separates the intestinal microflora from cells of the immune system. In addition to its barrier function, the intestinal epithelium expresses defensins, natural, endogenous antimicrobial peptides. I...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.10.035

    authors： Zhao A,Lu W,de Leeuw E

    更新日期：2015-11-27 00:00:00

  • TTX resistivity of Na+ channel in newt retinal neuron.

    abstract：:We examined voltage-dependent, TTX-resistant Na+ channels of newt retina (nRNaCh) electrophysiologically. IC50-TTX value of nRNaCh is more than 20 microM. We determined partial cDNA sequences of nRNaCh restricted to TTX binding sites (SS2 regions of all four repeats). While the amino acid sequences of SS2 regions of r...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7696

    authors： Kaneko Y,Matsumoto G,Hanyu Y

    更新日期：1997-11-26 00:00:00

  • Transcriptional activation of EGFR by HOXB5 and its role in breast cancer cell invasion.

    abstract：:HOX genes are transcription factors that play important roles in body patterning and many cellular processes during embryonic, fetal, and adult development. Given their important function in normal tissues, it is reasonable to assume that abnormal expression of HOX genes in adults could lead to serious diseases such a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.08.071

    authors： Lee JY,Kim JM,Jeong DS,Kim MH

    更新日期：2018-09-18 00:00:00

  • Bortezomib sensitizes human glioblastoma cells to induction of apoptosis by type I interferons through NOXA expression and Mcl-1 cleavage.

    abstract：:Glioblastomas are highly invasive and aggressive primary brain tumors. Type I interferons have significant, pleiotropic anticancer activity. However, through various pathways many cancers become interferon-resistant, limiting interferon's clinical utility. In this study, we demonstrated that the proteasomal inhibitor ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.07.080

    authors： Wang R,Davidoff AM,Pfeffer LM

    更新日期：2016-09-09 00:00:00

  • Characterization of fibrillation process of alpha-synuclein at the initial stage.

    abstract：:alpha-Synuclein is the major component of the filamentous Lewy bodies and Lewy-related neurites, neuropathological hallmarks of Parkinson's disease. Although numerous studies on alpha-synuclein fibrillation have been reported, the molecular mechanisms of aggregation and fibrillation at the initial stage are still uncl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.02.127

    authors： Tashiro M,Kojima M,Kihara H,Kasai K,Kamiyoshihara T,Uéda K,Shimotakahara S

    更新日期：2008-05-09 00:00:00

  • Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association.

    abstract：:Despite the mitochondria ubiquitous nature many of their components display divergences in their expression profile across different tissues. Using the bioinformatics-approach of guilt by association (GBA) we exploited these variations to predict the function of two so far poorly annotated genes: Coiled-coil-helix-coi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.09.109

    authors： Martherus RS,Sluiter W,Timmer ED,VanHerle SJ,Smeets HJ,Ayoubi TA

    更新日期：2010-11-12 00:00:00

  • Induction of histidine decarboxylase in rat basophilic leukemia cells by interferon and prevention of its effect in coincubation with ADP-ribosyltransferase inhibitors.

    abstract：:Treatment of rat basophilic leukemia cell line (2H3) with interferon-alpha significantly increased intracellular histamine levels. On the other hand, the histidine content was decreased reciprocally by interferon in a dose-dependent manner. Concomitantly, the activity of histidine decarboxylase, the enzyme responsible...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(89)80181-0

    authors： Kito T,Kubota M,Takimoto T,Akiyama Y,Heike T,Mikawa H

    更新日期：1989-01-16 00:00:00

  • Interaction of DNA hairpin loops and a complementary strand by a triplet of base pairs.

    abstract：:Hypothesis of non-enzymatic recognition of primordial tRNA and mRNA precursors is experimentally approached. DNA hairpins containing a different number of deoxyguanosine residues in the loop are analyzed for their binding ability to a chemically fixed single-strand of oligo(dC). In presence of small Mg2+ concentration...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80971-9

    authors： Baumann U,Frank R,Blöcker H

    更新日期：1988-12-30 00:00:00

  • Characteristics of alpha-adrenoceptors in two human colorectal cancer cell lines.

    abstract：:The DiFi and HT-29 human colorectal cancer cell lines were characterized and compared with respect to binding properties of alpha adrenoceptors present on the cell surface. Both cell lines possessed alpha-1 and alpha-2 adrenoceptors of high affinity; however, DiFi cells were rich in alpha-1 adrenoceptors, whereas HT-2...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80972-6

    authors： Agrawal DK,Wildrick DM,Boman BM

    更新日期：1992-05-29 00:00:00

  • Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif.

    abstract：:Groucho is a protein implicated in Notch signaling and involved in segmentation and neural development in Drosophila. Groucho forms transcription complexes with the basic helix-loop-helix proteins encoded by the hairy/Enhancer of split ("hairy-like") gene family. These interactions are mediated by the carboxyl-termina...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.0959

    authors： Grbavec D,Stifani S

    更新日期：1996-06-25 00:00:00

  • The yeast Pdr5p multidrug transporter: how does it recognize so many substrates?

    abstract：:Multidrug transporters are of considerable importance because they present problems in the treatment of infectious disease and cancer. A central issue is the ability of efflux pumps to recognize an astounding array of structurally diverse compounds. The yeast Pdr5p efflux pump, which is a member of the ATP-binding cas...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/j.bbrc.2007.02.011

    authors： Golin J,Ambudkar SV,May L

    更新日期：2007-04-27 00:00:00

  • Aberrant expression of SIRT3 is conversely correlated with the progression and prognosis of human gastric cancer.

    abstract：:SIRT3 is a NAD(+)-dependent histone deacetylaseand and plays a critical role in various human carcinomas. However, its precise role in the pathogenesis of gastric cancer (GC) is still unclear. Western blot and Real-Time PCR were used to detect the protein and mRNA level of SIRT3 in freshly collected samples from GC pa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.11.068

    authors： Yang B,Fu X,Shao L,Ding Y,Zeng D

    更新日期：2014-01-03 00:00:00

  • Effect of boric acid solution on cartilage metabolism.

    abstract：:Pelvic cartilage of chick embryo was used to demonstrate that presence of boron in culture medium decreases synthesis of proteoglycans, collagen and total proteins but on the other hand increases the release of these macromolecules. However, when glucose concentration in culture medium is brought to 22mM, the synthesi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.6621

    authors： Benderdour M,Hess K,Gadet MD,Dousset B,Nabet P,Belleville F

    更新日期：1997-05-08 00:00:00

  • Bacterial DNA methylation and gene transfer efficiency.

    abstract：:The necessary amplification step in bacteria of any plasmid currently used in DNA immunization or gene therapy introduces modification in the nucleotide sequence of plasmid DNA used in gene transfer. These changes affect the adenine and the internal cytosine in respectively all of the GATC and CC(A/T)GG sequences. The...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3603

    authors： Allamane S,Jourdes P,Ratel D,Vicat JM,Dupré I,Lainé M,Berger F,Benabid AL,Wion D

    更新日期：2000-10-05 00:00:00

  • Hypothalamic gene expression in long-term fasted rats: relationship with body fat.

    abstract：:Many hypothalamic neuropeptides are involved in the regulation of energy homeostasis and feeding behavior. We have investigated whether and to what extent neuropeptide Y (NPY), agouti-related protein (AGRP), melanin-concentrating hormone (MCH), and prepro-orexin (prepro-OX) as well as pro-opiomelanocortin (POMC) and c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)00481-9

    authors： Bertile F,Oudart H,Criscuolo F,Maho YL,Raclot T

    更新日期：2003-04-18 00:00:00

  • Affinity purification of HIV-1 and HIV-2 proteases from recombinant E. coli strains using pepstatin-agarose.

    abstract：:A procedure is described which employs pepstatin-agarose for the affinity purification of either HIV-1 or HIV-2 protease from two similar recombinant E. coli constructs that were developed for the expression of these enzymes. HIV-2 protease was routinely expressed at much higher levels than the HIV-1 enzyme and pepsta...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)91356-w

    authors： Rittenhouse J,Turon MC,Helfrich RJ,Albrecht KS,Weigl D,Simmer RL,Mordini F,Erickson J,Kohlbrenner WE

    更新日期：1990-08-31 00:00:00

  • Novel azacyclic ureas that are potent inhibitors of HIV-1 protease.

    abstract：:A series of novel, azacyclic ureas which are highly potent inhibitors of the HIV-1 protease (IC50 = 4.1 to < 0.5 nM) were synthesized. Aqueous solubilities of this series of compounds were improved by incorporating polar functional groups at the P1' P2 and P2' positions. These compounds also possess good anti-viral ac...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.1191

    authors： Sham HL,Zhao C,Marsh KC,Betebenner DA,Lin S,Rosenbrook W Jr,Herrin T,Li L,Madigan D,Vasavanonda S,Molla A,Saldivar A,McDonald E,Wideburg NE,Kempf D,Norbeck DW,Plattner JJ

    更新日期：1996-08-14 00:00:00

  • Curative and protective effects of L-arginine on carbon tetrachloride-induced hepatotoxicity in mice.

    abstract：:L-arginine may aid in the liver detoxification and may benefit in the treatment of liver disorders such as liver injury. The present study was to investigate the possible protective and curative effects of L-arginine on carbon tetrachloride (CCl(4)) induced hepatotoxicity. Mice received a single dose of CCl(4). L-argi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.05.102

    authors： Saad EA

    更新日期：2012-06-22 00:00:00

  • Bcl-2 protects against Abeta(25-35)-induced oxidative PC12 cell death by potentiation of antioxidant capacity.

    abstract：:A substantial body of data indicates that reactive oxygen intermediates (ROIs) are implicated in pathogenesis of diverse human diseases. Oxidative stress induced by ROIs often causes cell death via apoptosis that is regulated by a plenty of functional genes and their protein products. Bcl-2 is one such protein that bl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.06.035

    authors： Jang JH,Surh YJ

    更新日期：2004-07-30 00:00:00