Abstract:
:Polymer gel dosimetry aims to provide three-dimensional images of radiation therapy dose distributions in irradiated aqueous gels. The first gels required manufacture in an oxygen-free environment, but later the MAGIC formulation was introduced, which could be made in normal atmospheric conditions. Here we report our studies of the effects of variations in the composition of the MAGIC gel performed in order to optimize its performance over the useful dose range of 0 to 20 Gy. A new formulation (termed 'MAGIC-2') is comprised of 87% water, 4% methacrylic acid, 9% gelatin, 17.38 x 10(-6) M Cu(2+) and a molar ratio of ascorbic acid to [Cu(2+)] of 1000:1. MAGIC-2 has a dose-response slope-to-intercept ratio that is 78% greater than the original formulation and other more favorable properties.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Luci JJ,Whitney HM,Gore JCdoi
10.1088/0031-9155/52/10/N03subject
Has Abstractpub_date
2007-05-21 00:00:00pages
N241-8issue
10eissn
0031-9155issn
1361-6560pii
S0031-9155(07)32701-2journal_volume
52pub_type
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