Abstract:
:This paper evaluates results of a survey of electrostimulation models of myelinated nerve. Participants were asked to determine thresholds of excitation for 18 cases involving different characteristics of the neuron, the stimulation waveform, and the electrode arrangement. Responses were received from 7 investigators using 10 models. Excitation thresholds differed significantly among these models. For example, with a 2 ms monophasic stimulus pulse and an electrode/fiber distance of 1 cm, thresholds from the least to greatest value differed by a factor of 8.3; with a 5 μs pulse, thresholds differed by the factor 3.8. Significant differences in reported simulations point to the need for experimental validation. Additional efforts are needed to develop computational models for unmyelinated C-fibers, A-delta fibers, CNS neurons, and CNS Synapses.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Reilly JPdoi
10.1088/0031-9155/61/12/4346subject
Has Abstractpub_date
2016-06-21 00:00:00pages
4346-63issue
12eissn
0031-9155issn
1361-6560journal_volume
61pub_type
杂志文章abstract::The prompt-gamma neutron activation facility at Brookhaven National Laboratory was upgraded to improve both the precision and accuracy of its in vivo determinations of total body nitrogen. The upgrade, guided by Monte Carlo simulations, involved elongating and modifying the source collimator and its shielding, reposit...
journal_title:Physics in medicine and biology
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journal_title:Physics in medicine and biology
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journal_title:Physics in medicine and biology
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journal_title:Physics in medicine and biology
pub_type: 临床试验,杂志文章
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