Voltage clamp analysis of ethanol effects on pacemaker currents of Aplysia neurons.

abstract：:The effects of adenosine on the voltage-sensitive delayed-rectifier K+ (IK) currents and hyperpolarization-activated cationic inward current (Ih) were studied in cultured frog melanotrophs using the whole-cell configuration of the patch-clamp technique. The A1 receptor agonist R-N6-phenylisopropyl-adenosine (R-PIA; 50...

journal_title：Brain research

authors： Mei YA,Soriani O,Castel H,Vaudry H,Cazin L

更新日期：1998-05-18 00:00:00

abstract：:The distribution of bFGF in mouse and rat retinas was established using an antibody generated against a rat specific bFGF sequence. The patterns established with this antibody were distinctly different in comparison to the immunostaining patterns using antibodies prepared against similar regions of bovine and human bF...

journal_title：Brain research

authors： Gao H,Hollyfield JG

更新日期：1992-07-10 00:00:00

abstract：:Our previous studies indicated that L-type calcium channel blocker diltiazem could potentiate pentobarbital-induced hypnosis through serotonergic system. In view of the important role of dorsal raphe nucleus (DRN) on the sleep regulation and the pharmacological actions of calcium channel blocker, we presumed that Ca(2...

journal_title：Brain research

authors： Cui SY,Cui XY,Zhang J,Wang ZJ,Yu B,Sheng ZF,Zhang XQ,Shi XL,Zhang YH

更新日期：2011-07-27 00:00:00

abstract：:Calcium-binding proteins play a critical role in vertebrate sensory cells, and some of them have been detected in mechanosensory and chemosensory cells of bony and cartilaginous fishes. In this study immunohistochemistry and Western blot were used to investigate the occurrence and the distribution of S100 protein and ...

journal_title：Brain research

authors： Germanà A,Paruta S,Germanà GP,Ochoa-Erena FJ,Montalbano G,Cobo J,Vega JA

更新日期：2007-08-08 00:00:00

abstract：:This study examines the role of catecholamines, cell bodies and fibers of passage within the subcoeruleus area (subLC) in the arginine vasopressin (AVP) response to splanchnic osmotic stimulation and hemorrhage. Bilateral chemical lesions were induced into the subLC, approximately 1 mm ventral to the locus coeruleus (...

journal_title：Brain research

authors： King MS,Baertschi AJ

更新日期：1992-05-15 00:00:00

abstract：:The present in vitro study was performed to characterize neurons within dorsal regions of the nucleus tractus solitarii (NTS), principally at the level of area postrema, and known to receive inputs predominantly from cardiovascular and respiratory afferents (i.e. cardiorespiratory NTS). This report describes 4 classes...

journal_title：Brain research

authors： Paton JF,Foster WR,Schwaber JS

更新日期：1993-02-26 00:00:00

abstract：:Recent studies suggest that both sex and cerebral hemisphere influence brain mechanisms associated with emotional memory. Here we used evoked potentials to examine the influence of sex and hemisphere on brain responses to emotional stimuli. Given that the P300 component of the event-related brain potential (ERP) is co...

journal_title：Brain research

authors： Gasbarri A,Arnone B,Pompili A,Pacitti F,Pacitti C,Cahill L

更新日期：2007-03-23 00:00:00

abstract：:Heme oxygenase-carbon monoxide-cGMP (HO-CO-cGMP) pathway has been reported to be involved in peripheral and spinal modulation of inflammatory pain. However, the involvement of this pathway in the modulation of acute painful stimulus in the absence of inflammation remains unknown. Thus, we evaluated the involvement of ...

journal_title：Brain research

authors： Carvalho PG,Branco LG,Panissi CR

更新日期：2011-04-18 00:00:00

abstract：:Antimitotic drugs used in the chemotherapeutic treatment of cancers induce undesirable but unavoidable side-effects from interruption of normal mitotic processes throughout the body. We have examined whether several such drugs capable of penetrating the blood-brain barrier - thioTEPA and 5-fluorouracil - influence the...

journal_title：Brain research

authors： Mignone RG,Weber ET

更新日期：2006-09-21 00:00:00

abstract：:The distribution of fast axonally transported proteins was studied by electron microscope radioautography in ciliary ganglia of chickens treated or not treated with acrylamide. At 3 h after the intracerebral injection of [3H]lysine, the preganglionic axons of the untreated chickens displayed few silver grains, mainly ...

journal_title：Brain research

authors： Chretien M,Patey G,Souyri F,Droz B

更新日期：1981-01-26 00:00:00

abstract：:Perceptual performance in persons with hearing loss, especially those using devices to restore hearing, is not fully predicted by traditional audiometric measurements designed to evaluate the status of peripheral function. The integrity of auditory brainstem synapses may vary with different forms of hearing loss, and ...

journal_title：Brain research

authors： McGuire B,Fiorillo B,Ryugo DK,Lauer AM

更新日期：2015-04-24 00:00:00

abstract：:The epileptogenic properties of the mast cell degranulating peptide (MCD) have been investigated in the CA3 region of the hippocampal slice preparation. Brief (3-5 min) bath application of MCD (0.5-2 microM) to CA3 hippocampal neurones produced an enhancement of the spontaneous synaptic activity and the appearance of ...

journal_title：Brain research

authors： Cherubini E,Neuman R,Rovira C,Ben Ari Y

更新日期：1988-03-29 00:00:00

abstract：:The localization of a GTP-binding protein (G(o)) in the cerebellar and cerebral cortex and hippocampus of the normal and reeler mutant mouse was immunohistochemically examined using affinity-purified antibody raised against the alpha subunit of G(o). Although the general distribution pattern of G(o)-immunoreactive pro...

journal_title：Brain research

authors： Terashima T,Katada T,Ichikawa R,Ui M,Inoue Y

更新日期：1993-01-22 00:00:00

abstract：:Substance P(SP), the heptapeptide SP and the stable analogue (p-Glu5-MePhe8-MeGly9) SP (DiMe-C7) induce a Ca2+-dependent release of Met5-enkephalin (MET) from slices of periaqueductal gray matter (PAG) and striatum of rats. The MET release from striatal slices is greater than that from PAG slices because of the higher...

journal_title：Brain research

authors： Del Río J,Naranjo JR,Yang HY,Costa E

更新日期：1983-11-21 00:00:00

abstract：BACKGROUND:Sex-specific trajectories in white matter development during adolescence may help explain cognitive and behavioral divergences between males and females. Knowledge of sex differences in typically developing adolescents can provide a basis for interpreting sexual dimorphisms in abilities and actions. METHOD:...

journal_title：Brain research

authors： Bava S,Boucquey V,Goldenberg D,Thayer RE,Ward M,Jacobus J,Tapert SF

更新日期：2011-02-23 00:00:00

abstract：:The postnatal development of soma size and cytochrome oxidase activity was examined in the perigeniculate nucleus (PGN) and reticular nucleus of the thalamus (RNT). Neurons in the PGN and RNT exhibited a rapid increase in soma size between 2 and 4 weeks of age. During this period of cell growth there is an increase in...

journal_title：Brain research

authors： Murakami DM,Condo GJ,Wilson PD

更新日期：1987-10-01 00:00:00

abstract：:By use of the push-pull perfusion technique, release of neuronal cholecystokinin-like immunoreactivity (CCK-LI) from hypothalamus of owl monkeys was investigated in relation to an intragastric meal. In overnight fasted, halothane-anesthetized owl monkeys, levels of CCK-LI in the hypothalamic push-pull perfusate were b...

journal_title：Brain research

authors： Schick RR,Reilly WM,Roddy DR,Yaksh TL,Go VL

更新日期：1987-08-18 00:00:00

abstract：:Following single injections of horseradish peroxidase (HRP) in the superior colliculus (SC) and [3H]proline in the striate cortex of rats, a close correspondence was observed in the topographical arrangements of extrastriate cortical fields of HRP retrograde label and of isotope anterograde label. These results suppor...

journal_title：Brain research

authors： Olavarria J,Van Sluyters RC

更新日期：1982-06-24 00:00:00

abstract：:The present study evaluated whether environmental enrichment-related effects on the development of stereotyped behavior in deer mice were associated with alterations in neuronal metabolic activity. Deer mice were reared under either enriched or standard housing conditions for 60 days following weaning. All mice were t...

journal_title：Brain research

authors： Turner CA,Yang MC,Lewis MH

更新日期：2002-05-31 00:00:00

abstract：:Electroconvulsive therapy (ECT) is widely used as a treatment for drug-resistant depression. The animal analogue of ECT is electroconvulsive shock (ECS) seizures. We have recently shown that repeated ECS seizures cause a long-lasting, perhaps permanent, enhancement in entorhinal-dentate evoked potentials in the rat. O...

journal_title：Brain research

authors： Gombos Z,Mendonça A,Racine RJ,Cottrell GA,Burnham WM

更新日期：1997-08-22 00:00:00

abstract：:The intercollicular pathway of the rat was studied using autoradiographic (ARG) and horseradish peroxidase (HRP) tracing techniques. The HRP experiments demonstrated that the cells of origin of the intertectal pathway were located primarily in the rostral stratum griseum intermediale ( SGI ), stratum album intermedium...

journal_title：Brain research

authors： Yamasaki DS,Krauthamer G,Rhoades RW

更新日期：1984-05-23 00:00:00

abstract：:Dravet syndrome (DS) is a genetic form of severe epilepsy often associated with mutation of the SCN1A gene encoding the voltage gated sodium channel Nav1.1. Typically refractive to conventional therapy, serotonin neurotransmission may be an innovative target for treatment. To further understand the role of serotonin i...

journal_title：Brain research

authors： Hatini PG,Commons KG

更新日期：2019-12-01 00:00:00

abstract：:Prairie voles (Microtus ochrogaster) are monogamous rodents that display high levels of affiliative behaviors, including pair-bonding, biparental care, and cooperative breeding. Species differences in basal cocaine- and amphetamine-regulated transcript (CART) mRNA and peptide expression have been found between prairie...

journal_title：Brain research

authors： Hostetler CM,Kowalczyk AS,Griffin LL,Bales KL

更新日期：2011-09-26 00:00:00

abstract：:Epileptiform activity induced by 4-AP in hippocampal area CA1 is characterised by short recurrent discharges. These are occasionally superimposed by slow field potential (fp) shifts. Simultaneous recordings of fps and [K(+)](o) in area CA1 and temporal cortex showed a slow fp shift in both regions, but associated rise...

journal_title：Brain research

authors： Breustedt J,Gloveli T,Heinemann U

更新日期：2002-11-22 00:00:00

abstract：:Dynamin-1 is a multi-domain GTPase that is crucial for the fission stage of synaptic vesicle recycling and vesicle trafficking. In this study, we constructed prokaryotic expression plasmids for the four functional domains of dynamin-1, which are pGEX-4T-2-PH, pGEX-4T-2-PRD, pGEX-4T-2-GED and pGEX-4T-2-GTPase. Glutathi...

journal_title：Brain research

authors： Zhang C,Omran AG,He F,Deng X,Wu L,Peng J,Yin F

更新日期：2014-01-16 00:00:00

abstract：:The endocannabinoid system is a promising therapeutic target in a wide variety of diseases. However, the non-desirable psychotropic effects of natural and synthetic cannabinoids have largely counteracted their clinical usefulness. These effects are mostly mediated by cannabinoid receptors of the CB(1) type, that exhib...

journal_title：Brain research

authors： Tolón RM,Núñez E,Pazos MR,Benito C,Castillo AI,Martínez-Orgado JA,Romero J

更新日期：2009-08-04 00:00:00

abstract：:Zinc ions seem to be important to several neurological functions and have been connected to the pathophysiology of epilepsy, neuronal cell death after seizure or stroke, and Alzheimer's disease. Both epilepsy and Alzheimer's disease are clinical conditions believed to involve the olfactory bulb. The mammalian olfactor...

journal_title：Brain research

authors： Mook Jo S,Kuk Kim Y,Wang Z,Danscher G

更新日期：2002-11-29 00:00:00

abstract：:The distribution of avian pancreatic polypeptide (APP)-like immunoreactivity (APP-IR) in the chicken retina was investigated by means of immunohistochemistry. The observation from frozen sections showed that APP-IR is localized in the stratified amacrine cells of the first sublayer. Examination of whole-mounts reveale...

journal_title：Brain research

authors： Katayama Y,Kiyama H,Arai Y,Tohyama M

更新日期：1984-09-17 00:00:00

abstract：:The present study gives a detailed description of the functional characteristics and of the topographic distribution of responses mediated through the climbing fiber (CF) pathway in the cerebellum of adult rats which have been repeatedly irradiated from birth so that the Purkinje cells (PCs) in the adult remained inne...

journal_title：Brain research

authors： Mariani J,Mulle C,Geoffroy B,Delhaye-Bouchaud N

更新日期：1987-09-22 00:00:00

abstract：:The lateral hypothalamus (LH) is a site of integration for control mechanisms of feeding behavior as it has extensive reciprocal connections with multiple intrahypothalamic and extrahypothalamic brain areas. Evidence suggests that blockade of ionotropric gamma-aminobutyric acid (GABA) receptors in the LH elicits eatin...

journal_title：Brain research

authors： Turenius CI,Charles JR,Tsai DH,Ebersole PL,Htut MH,Ngo PT,Lara RN,Stanley BG

更新日期：2009-08-04 00:00:00