Abstract：
:Epileptiform activity induced by 4-AP in hippocampal area CA1 is characterised by short recurrent discharges. These are occasionally superimposed by slow field potential (fp) shifts. Simultaneous recordings of fps and [K(+)](o) in area CA1 and temporal cortex showed a slow fp shift in both regions, but associated rises in [K(+)](o) occurred only in the cortex. Slow fps in area CA1 persisted after disruption of the perforant path, but were abolished after removal of the adjacent cortex from the hippocampus. These findings suggest that slow fps in CA1 can represent far field effects of seizure like events generated in neighbouring cortex.
journal_name
Brain Resjournal_title
Brain researchauthors
Breustedt J,Gloveli T,Heinemann Udoi
10.1016/s0006-8993(02)03541-2subject
Has Abstractpub_date
2002-11-22 00:00:00pages
173-7issue
1eissn
0006-8993issn
1872-6240pii
S0006899302035412journal_volume
956pub_type
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