Abstract:
:The complete genome sequence of the Liaoning isolate of the Antheraea pernyi multinucleocapsid nucleopolyhedrovirus (AnpeMNPV) was determined. The viral genome size is 126,246 bp, relatively GC-rich (53.5% G+C), with 145 predicted open reading frames (ORFs) of more than 50 amino acids, accounting for more than 97% of the genome. 97% of the ORFs have predicted functions or homologues in other baculoviruses. There are six homologous repeat regions (hrs) and two bro homologues, which are associated with regions of genome instability. The virus lacks the p35 homologue but encodes two members of the inhibitors of apoptosis (iap) gene family. The presence of a gp64 homologue in the AnpeMNPV genome and results from gene parity plot and phylogenetic analysis using the 29 core baculovirus genes clearly classify AnpeMNPV as a group I NPV. The divergence of genome sequences in two geographical NPV isolates suggests of great genetic heterogeneity of baculovirus populations in nature.
journal_name
Virologyjournal_title
Virologyauthors
Fan Q,Li S,Wang L,Zhang B,Ye B,Zhao Z,Cui Ldoi
10.1016/j.virol.2007.04.027subject
Has Abstractpub_date
2007-09-30 00:00:00pages
304-15issue
2eissn
0042-6822issn
1096-0341pii
S0042-6822(07)00317-0journal_volume
366pub_type
杂志文章相关文献
VIROLOGY文献大全abstract::The human papillomavirus type 16 E1--E4 protein is expressed abundantly in cells supporting viral DNA amplification, but its expression is lost during malignant progression. In cell culture, 16E1--E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. Here, we ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2006.02.024
更新日期:2006-05-25 00:00:00
abstract::The glycoprotein (GP) of lymphocytic choriomeningitis virus (LCMV) serves as virus attachment protein to its receptor on host cells and is a key determinant for cell tropism, pathogenesis, and epidemiology of the virus. The GP of LCMV is posttranslationally cleaved by the subtilase SKI-1/S1P into two subunits, the per...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/s0042-6822(03)00421-5
更新日期:2003-09-15 00:00:00
abstract::Cauliflower mosaic virus (CaMV) strains CM1841 and W260 produced markedly different symptoms when inoculated onto turnips (Brassica campestris L. 'Just Right'). The CM1841 strain induced a mild degree of stunting of infected plants while strain W260 caused moderate to severe stunting. Although CM1841 was significantly...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(91)90898-l
更新日期:1991-04-01 00:00:00
abstract::The recent identification of a novel human coronavirus responsible of a SARS-like illness in the Middle-East a decade after the SARS pandemic, demonstrates that reemergence of a SARS-like coronavirus from an animal reservoir remains a credible threat. Because SARS is contracted by aerosolized contamination of the resp...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2014.01.002
更新日期:2014-03-01 00:00:00
abstract::Monoclonal antibodies (MAb) against an O1 Suisse isolate of FMDV were used to identify epitopes on the virus particle and to determine their relative function. Six major antigenic sites containing one or more epitopes were identified using competition ELISA. An epitope relationship is proposed consisting of a trypsin-...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(87)90294-7
更新日期:1987-04-01 00:00:00
abstract::Attempts to define the genetic determinants required for efficient growth of human immunodeficiency virus type 1 (HIV-1) in monocyte-macrophages were made by constructing chimeras between two infectious clones of HIV-1 (HXB2 and LW/C), which despite only minor differences in their DNA sequence have striking difference...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/s0042-6822(95)80082-4
更新日期:1995-01-10 00:00:00
abstract::The HSV-1 genome is composed of two unique regions (UL and US) flanked by inverted repeats. During the course of DNA replication the two unique regions UL and US invert relative to one another. In this report we present evidence that cleavage is not necessary for genomic inversion to occur. We isolated and characteriz...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1996.0668
更新日期:1996-12-15 00:00:00
abstract::Encephalitis is a rare, but serious complication from vaccination against smallpox using replication competent strains of vaccinia virus. In this report we describe mutants of vaccinia virus, containing N-terminal deletions of the vaccinia virus interferon resistance gene, E3L, that are attenuated for neuropathogenesi...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2005.01.006
更新日期:2005-03-15 00:00:00
abstract::West Nile virus (WNV) genome cyclization is mediated by two pairs of long-distance RNA/RNA interactions: the 5'CS/3'CSI (conserved sequence) and the 5'UAR/3'UAR (upstream AUG region) base pairings. Antisense peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs), designed to interfere with the 5'CS/3'CSI o...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2008.08.044
更新日期:2008-12-05 00:00:00
abstract::Sequences critical for the activity of the measles virus (MV) RNA polymerase in transcription and replication were analyzed using a MV genomic cDNA library containing overlapping clones encompassing the entire MV genome. Clones corresponding to the 3' and 5' ends of the MV genome were identified and sequenced, and the...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(88)90564-8
更新日期:1988-06-01 00:00:00
abstract::The second smallest subgenomic messenger RNA, mRNA5, of the coronavirus infectious bronchitis virus includes in its "5' unique region" two separate open reading frames (5a and 5b), whose coding function has not so far been established, and thus it may represent a dicistronic messenger RNA. We report here that two poly...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(92)90094-6
更新日期:1992-01-01 00:00:00
abstract::The protein content of vaccinia virus mature virions, purified by rate zonal and isopycnic centrifugations and solubilized by SDS or a solution of urea and thiourea, was determined by the accurate mass and time tag technology which uses both tandem mass spectrometry and Fourier transform-ion cyclotron resonance mass s...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2006.08.025
更新日期:2007-02-05 00:00:00
abstract::While the 2009 pandemic H1N1 virus has become established in the human population as a seasonal influenza virus, continued adaptation may alter viral virulence. Here, we passaged a 2009 pandemic H1N1 virus (A/Changchun/01/2009) in mice. Serial passage in mice generated viral variants with increased virulence. Adapted ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2015.09.014
更新日期:2015-12-01 00:00:00
abstract::Recently, we reported that in vitro and in vivo persistent infection of neurons by lymphocytic choriomeningitis virus (LCMV) downregulated GAP43 expression, a protein involved in neuronal plasticity associated with learning and memory. Here, we investigated the transcriptional and posttranscriptional events involved. ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1997.8458
更新日期:1997-04-14 00:00:00
abstract::A human B-lymphoid cell line, designated TG8, which does not express detectable levels of the EBV (Epstein-Barr virus)-associated nuclear antigen (EBNA), yet carries an average of one to two plasmid copies of the P3HR-1 EBV genome has been identified. TG8 can be superinfected by B95-8 EBV, resulting in up to 60-70% of...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90014-x
更新日期:1984-08-01 00:00:00
abstract::Infection of human helper T lymphocytes with the human immunodeficiency virus (HIV) results in a rapid induction of cytopathic effects and cell lysis. We isolated a variant of the human T-lymphoblastoid cell line, CEM, that is fully susceptible to HIV infection but resistant to virally induced cytopathic effects. Expo...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(87)90434-x
更新日期:1987-01-01 00:00:00
abstract::The antigenic structure of the VP4 protein of human rotavirus (HRV) strains Wa and ST3 was studied by using a panel of Wa- and ST3-derived VP4-specific neutralizing monoclonal antibodies (NMAbs) and NMAb-resistant variants. The VP4-coding genes from three Wa and three ST3 variants were sequenced. For Wa VP4, one homot...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/s0042-6822(95)80029-8
更新日期:1995-01-10 00:00:00
abstract::The emergence and re-emergence of Zika virus (ZIKV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas worldwide. Despite these burdens, antiviral therapies do not exist, and inhibitors of ZIKV are therefore urgently needed. To...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2020.04.009
更新日期:2020-07-01 00:00:00
abstract::The genome of the sigma rhabdovirus of Drosophila melanogaster consists of six genes in the order 3' N-2-3-4-G-L 5'. The nucleotide sequences of the N and of the fourth genes were determined from cDNA clones. Each gene contained a single long open reading frame encoding polypeptides with predicted MW of 50 and 25 kDa,...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1994.1177
更新日期:1994-04-01 00:00:00
abstract::The DNAs from the granulosis viruses of Plodia interpunctella and Pieris rapae were clearly distinguishable based on restriction endonuclease fragment patterns. By sizing single- and double-digestion products approximate molecular weights of 72 x 10(2) and 75 x 10(6), respectively, were estimated for the viral genomes...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(80)90357-8
更新日期:1980-07-30 00:00:00
abstract::We have quantitated replication of the RNA genomes of vesicular stomatitis virus (VSV) and its defective interfering (DI) particles in a BHK21 cell-free system into which nucleocapsids were introduced in varying amounts and ratios, with or without addition of purified virus polymerase components. The quantitative tran...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(89)90375-9
更新日期:1989-05-01 00:00:00
abstract::Infections of nonpermissive ( sup0 ) Escherichia coli by T1 phage with amber mutations in either gene 3.5 or gene 4 exhibit a variety of defective phenotypes, including premature arrest of T1 DNA synthesis, failure to make concatemeric DNA, formation of an abnormal DNA replication intermediate, failure to package phag...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90130-2
更新日期:1984-05-01 00:00:00
abstract::The monoclonal antibody 2D5 neutralized vaccinia virus by preventing penetration of the virus and reacting with VP23-29K. The conformation of the VP23-29K was maintained by a disulfide bond(s), and the 2D5mAb reacted stronger with the nonreduced 23-kDa form than with the reduced 29-kDa form. We selected several escape...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1996.0337
更新日期:1996-06-15 00:00:00
abstract::An insertion mutation in the pol gene of Moloney murine leukemia virus (M-MuLV) was found to render the virus temperature-sensitive for replication. A provirus containing a 12-bp insertion at the boundary between the reverse transcriptase (RT) and integrase (IN) domains induced the formation of mutant virions containi...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(89)90428-5
更新日期:1989-06-01 00:00:00
abstract::V-CATH, a cathepsin L-like cysteine protease encoded by the baculovirus Autographa californica M nucleopolyhedrovirus, has been shown to play an essential role in host liquefaction. Similar to cellular cathepsin L, V-CATH is synthesized as an inactive proenzyme and is activated by cleavage of the propeptide. Previous ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.2002.1378
更新日期:2002-05-10 00:00:00
abstract::Measles virus (MV) causes various responses including the induction of immune responses, transient immunosuppression and establishment of long-lasting immunity. To obtain a comprehensive view of the effects of MV infection on target cells, DNA microarray analyses of two different cell-types were performed. An epitheli...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2008.02.015
更新日期:2008-06-05 00:00:00
abstract::Monoclonal antibodies to avian sarcoma/leukosis virus-coded transforming, structural, and polymerase proteins have been developed. In this first communication, a monoclonal antibody to pp60src will be characterized. The antibody can bind to pp60src in radioimmunoassays, precipitates this antigen in protein kinase test...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90440-9
更新日期:1984-02-01 00:00:00
abstract::An analysis has been made of variants found in preparations of the common (U1) strain of tobacco mosaic virus (TMV) which had been obtained after the inoculum had been passaged through a necrotic local lesion. These lesions were induced with a minimal number of virions (3000 or 30,000) per inoculation point. The relat...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90097-7
更新日期:1984-01-15 00:00:00
abstract::Crystals of Cowpea mosaic virus displaying a high degree of order have been grown in two different forms. Hexagonal crystals, space group P6(1)22 or P6(5)22 with a = 450 A and c = 1038 A containing six virus particles per cell, have been grown in sodium citrate buffer at pH 4.9. Each particle has four nearest neighbor...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(80)90513-9
更新日期:1980-02-01 00:00:00
abstract::While trying to generate a site-directed deletion in the ORF63 latency-associated gene of varicella-zoster virus (VZV) Oka, we constructed a virus with an unexpected rearrangement. The virus has a small deletion in both copies of ORF63 and two copies of a cassette inserted between ORFs 64/65 and 68/69 containing (a) t...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2010.01.007
更新日期:2010-04-10 00:00:00