Activation of nit-1 nitrate reductase by W-formate dehydrogenase.

abstract：:Casein kinase II (CKII) activity in colorectal tumours was compared before and after heterotransplantation onto nude mice. The test revealed that the enzyme activity was about two-fold enhanced in the tumours isolated from the nude mice when compared to the respective primary tumours from which they were derived. Immu...

journal_title：Biochemical and biophysical research communications

authors： Seitz G,Münstermann U,Schneider HR,Issinger OG

更新日期：1989-08-30 00:00:00

abstract：:Reduction process of cucumber ascorbate oxidase with L-ascorbate was investigated in detail through absorption and electron paramagnetic resonance (EPR) spectra under anaerobic condition. One of the three type I coppers (the type I copper which is oxidized rapidly (Sakurai, T. et al. (1985) Biochem. Biophys. Res. Comm...

journal_title：Biochemical and biophysical research communications

authors： Sakurai T,Sawada S,Suzuki S,Nakahara A

更新日期：1986-03-13 00:00:00

abstract：:In order to study the role of phosphatidylinositol-3-kinase (PI3K) in insulin action, we employed a specific inhibitor of PI3K, LY294002, and measured five biological functions of insulin in mouse 3T3 fibroblasts overexpressing human insulin receptors. LY294002 had no effect on tyrosine phosphorylation of both the ins...

journal_title：Biochemical and biophysical research communications

authors： Sanchez-Margálet V,Goldfine ID,Vlahos CJ,Sung CK

更新日期：1994-10-28 00:00:00

abstract：:Oligodendrocytes (OLGs) are cells from the central nervous system that synthesize, assemble, and maintain myelin, the multilamellar membrane that surrounds axons and facilitates the fast conduction of nerve impulses. We have shown that OLGs initiate their myelinogenic phenotype upon adhesion to GRASP, a heparin-bindin...

journal_title：Biochemical and biophysical research communications

authors： Szuchet S,Plachetzki DC,Eaton KS

更新日期：2001-05-18 00:00:00

abstract：:Overexpression of AtNTRC (AtNTRC(OE)) in Arabidopsis thaliana led to a freezing and cold stress tolerance, whereas a knockout mutant (atntrc) showed a stress-sensitive phenotype. Biochemical analyses showed that the recombinant AtNTRC proteins exhibited a cryoprotective activity for malate dehydrogenase and lactic deh...

journal_title：Biochemical and biophysical research communications

authors： Moon JC,Lee S,Shin SY,Chae HB,Jung YJ,Jung HS,Lee KO,Lee JR,Lee SY

更新日期：2015-08-07 00:00:00

abstract：:The activation of c-jun N-terminal kinase (JNK) in pancreatic islets is associated with impaired function and viability, and JNK inhibitory peptides (JNKIs) are cytoprotective. In particular, l-isoforms of JNKIs were shown to improve islets viability, while the d-retroinverso isoform of JNKI (RI-JNKI), with a higher t...

journal_title：Biochemical and biophysical research communications

authors： Fornoni A,Cobianchi L,Sanabria NY,Pileggi A,Molano RD,Ichii H,Rosero S,Inverardi L,Ricordi C,Pastori RL

更新日期：2007-03-02 00:00:00

abstract：:Mutations of the GJB2 gene, encoding connexin 26, are the most common cause of hereditary congenital hearing loss in many countries and account for up to 50% of cases of autosomal-recessive non-syndromic deafness. By contrast, only a few GJB2 mutations have been reported to cause an autosomal-dominant form of non-synd...

journal_title：Biochemical and biophysical research communications

authors： Melchionda S,Bicego M,Marciano E,Franzè A,Morgutti M,Bortone G,Zelante L,Carella M,D'Andrea P

更新日期：2005-11-25 00:00:00

abstract：:We found citrulline-containing proteins in mouse peritoneal macrophages undergoing calcium ionophore-induced apoptosis. Such proteins were products of deimination of arginine residues catalyzed by endogenous peptidylarginine deiminase (EC 3.5.3.15) activated by calcium influx. Western blotting analyses of the extract ...

journal_title：Biochemical and biophysical research communications

authors： Asaga H,Yamada M,Senshu T

更新日期：1998-02-24 00:00:00

abstract：:Internal and environmental cues, including ambient temperature changes, regulate the timing of flowering in plants. Arabidopsis miR156 represses flowering and plays an important role in the regulation of temperature-responsive flowering. However, the molecular basis of miR156 processing at lower temperatures remains l...

journal_title：Biochemical and biophysical research communications

authors： Kim HE,Kim W,Lee AR,Jin S,Jun AR,Kim NK,Lee JH,Ahn JH

更新日期：2017-03-18 00:00:00

abstract：:The effects of compounds which bind in the DNA minor groove of A.T rich sequences, on bleomycin-catalyzed site-specific DNA cleavage were investigated by a DNA sequencing technique. Distamycin A enhanced bleomycin-catalyzed DNA cleavage in G.C rich sequences such as 5'-GGGGC-3' (under scoring; the cleaved nucleotide)....

journal_title：Biochemical and biophysical research communications

authors： Yamamoto K,Kawanishi S

更新日期：1992-02-28 00:00:00

abstract：:Methamphetamine induces several cardiac dysfunctions, which leads to arrhythmia, cardiac failure and sudden cardiac death. Although these cardiac alterations elicited by methamphetamine were thought to be due to an indirect action of methamphetamine, namely, an excessive catecholamine release from synaptic terminals, ...

journal_title：Biochemical and biophysical research communications

authors： Sugimoto K,Okamura K,Tanaka H,Takashima S,Ochi H,Yamamoto T,Matoba R

更新日期：2009-12-25 00:00:00

abstract：:Carbachol stimulated inositol trisphosphate (IP3) production and subsequent calcium mobilization in parotid cells are almost completely inhibited by neomycin. In contrast epinephrine stimulated IP3 production and calcium mobilization are much less sensitive to such inhibition. Since neomycin exerts its effects primari...

journal_title：Biochemical and biophysical research communications

authors： Kowatch MA,Roth GS

更新日期：1989-07-14 00:00:00

abstract：:Liposome-encapsulated clodronate (LEC) is a specific depletor of macrophages. Our study characterized the LEC depletory effects, given intrathecally, on spinal microglia and assessed its effects on initiation and maintenance of neuropathic pain. Measured by using the MTT assay, LEC treatment specifically inhibited cel...

journal_title：Biochemical and biophysical research communications

authors： Wang YR,Mao XF,Wu HY,Wang YX

更新日期：2018-05-15 00:00:00

abstract：:Mycobacterium tuberculosis, the causative agent of tuberculosis disease, is one among the deadliest pathogens in the world. Due to long treatment regimen, HIV co-infection, persistence of bacilli in latent form and development of XDR and TDR strains of Mtb, tuberculosis has posed serious concerns for managing the dise...

journal_title：Biochemical and biophysical research communications

authors： Gopalan A,Bhagavat R,Chandra N,Subbarao SH,Raja A,Bethunaickan R

更新日期：2018-02-12 00:00:00

abstract：:The objective of this study was to investigate the exact therapeutic effects of Verapamil on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the molecular mechanism involved, through using LPS-induced animal models as well as LPS-stimulated mouse primary peritoneal macrophages models. Our results demonstr...

journal_title：Biochemical and biophysical research communications

authors： Song Z,Li S,Zhang C,Yuan L,Han L,Liu Y

更新日期：2019-10-01 00:00:00

abstract：:Mutations of the glycogen branching enzyme gene, GBE1, result in glycogen storage disease (GSD) type IV, an autosomal recessive disorder having multiple clinical forms. One mutant allele of this gene, GBE1 c.1076A>C, has been reported in Ashkenazi Jewish cases of an adult-onset form of GSD type IV, adult polyglucosan ...

journal_title：Biochemical and biophysical research communications

authors： Hussain A,Armistead J,Gushulak L,Kruck C,Pind S,Triggs-Raine B,Natowicz MR

更新日期：2012-09-21 00:00:00

abstract：:Spinal and bulbar muscular atrophy (SBMA) is one of a group of human inherited neurodegenerative diseases caused by polyglutamine expansion. There is increasing evidence that generation of truncated proteins containing an expanded polyglutamine tract may be an important step in the pathogenesis of these disorders. We ...

journal_title：Biochemical and biophysical research communications

authors： Kobayashi Y,Miwa S,Merry DE,Kume A,Mei L,Doyu M,Sobue G

更新日期：1998-11-09 00:00:00

abstract：:Two polypeptides are involved in interleukin 2 binding: a low-affinity receptor of 55 kD (IL2-R alpha) and an intermediate affinity component of 75 kD (IL2-R beta). We describe the cloning by the Polymerase Chain Reaction of the coding region of IL2-R alpha from a human T-cell lymphoma cell line. One clone presented a...

journal_title：Biochemical and biophysical research communications

authors： Mercken L,Moras V,Hemon L,Lionne B,Bousseau A,Dautry-Varsat A,Collins M,Mayaux JF

更新日期：1991-11-14 00:00:00

abstract：:To gain further insight into the biochemical properties of the antibacterial hexetidine, isolated rat liver mitochondria were added with this drug and investigation made of certain features related to mitochondrial bioenergetics. Hexetidine was found to cause oxidation of intramitochondrial pyridine nucleotides and st...

journal_title：Biochemical and biophysical research communications

authors： D'Arcangelo G,Barile M,Passarella S,Quagliariello E

更新日期：1987-09-15 00:00:00

abstract：:While mutation of alpha-synuclein is a cause of autosomal-dominant Parkinson's disease (PD), it is still elusive as to how alpha-synuclein is involved in the pathogenesis of PD. Here, we show that dopamine-dependent accumulation of alpha-synuclein in cultured cells results in apoptosis. Furthermore, activation of insu...

journal_title：Biochemical and biophysical research communications

authors： Kao SY

更新日期：2009-07-31 00:00:00

abstract：:MicroRNAs are involved in cancer-related processes. The microRNA-21(miR-21) has been identified as the only miRNA over-expressed in a wide variety of cancers, including cervical cancer. However, the function of miR-21 is unknown in cervical carcinomas. In this study, we found that the inhibition of miR-21 in HeLa cerv...

journal_title：Biochemical and biophysical research communications

authors： Yao Q,Xu H,Zhang QQ,Zhou H,Qu LH

更新日期：2009-10-23 00:00:00

abstract：:The main transport mechanism of reabsorption of sodium bicarbonate and fluid in the renal proximal tubules involves Na(+)/H(+) exchanger 3 (NHE3), which is acutely and chronically downregulated by parathyroid hormone (PTH). Although PTH is known to exert an inhibitory effect on NHE3 expression and transcription, the m...

journal_title：Biochemical and biophysical research communications

authors： Neri EA,Bezerra CN,Queiroz-Leite GD,Polidoro JZ,Rebouças NA

更新日期：2015-06-12 00:00:00

abstract：:p66Shc plays a key role in oxidative stress-induced apoptosis. p66Shc gene expression is tissue-specific and controlled by promoter methylation. In T-cells p66Shc expression is induced by a variety of apoptotic stimuli. We have addressed the mechanisms regulating p66Shc expression in T-cells. We show that the increase...

journal_title：Biochemical and biophysical research communications

authors： Pezzicoli A,Ulivieri C,Capitani N,Ventura A,Pelicci P,Baldari CT

更新日期：2006-10-13 00:00:00

abstract：:X-linked juvenile retinoschisis (RS) is a bilateral vitreoretinal disorder with no known cure. The gene responsible for the disease was recently isolated by positional cloning methods and a spectrum of mutations has been described in families with RS pathology. In this report, we screened six sporadic cases of RS for ...

journal_title：Biochemical and biophysical research communications

authors： Hiraoka M,Trese MT,Shastry BS

更新日期：2000-02-16 00:00:00

abstract：:Angiogenesis is a key pathogenic event in hepatic fibrogenesis, which is mediated by activated hepatic stellate cells (HSCs). TNP-470 is a known anti-angiogenic agent in cancer, and in this study, we investigated the regulatory mechanisms of TNP-470 blockage of vascular endothelial growth factor (VEGF) synthesis in ac...

journal_title：Biochemical and biophysical research communications

authors： Wang YQ,Luk JM,Chu AC,Ikeda K,Man K,Kaneda K,Fan ST

更新日期：2006-03-03 00:00:00

abstract：:This report describes a relatively simple and reliable method for isolating adrenocortical mitochondria from rats in good, reasonably pure yield. These organelles, which heretofore have been unobtainable in isolated form from small laboratory animals, are now readily accessible. A high degree of mitochondrial purity i...

journal_title：Biochemical and biophysical research communications

authors： Solinas P,Fujioka H,Tandler B,Hoppel CL

更新日期：2012-10-12 00:00:00

abstract：:We have constructed a hybrid multicomponent dioxygenase gene cluster in which the bphA1 gene, coding for ISP alpha subunit of biphenyl dioxygenase from Pseudomonas pseudoalcaligenes KF707, has been replaced by the bedC1 gene encoding the corresponding subunit of benzene dioxygenase from P. putida ML2. Escherichia coli...

journal_title：Biochemical and biophysical research communications

authors： Tan HM,Cheong CM

更新日期：1994-10-28 00:00:00

abstract：:Endothelial cells line the inside of all blood vessels forming a structurally and functionally highly heterogenous population of cells. Here we describe the application of the differential RNA display technique to the analysis of the heterogeneity of endothelial cells. Multiple fragment cDNAs from quiescent resting an...

journal_title：Biochemical and biophysical research communications

authors： Kozian DH,Augustin HG

更新日期：1995-04-26 00:00:00

abstract：:The present study was performed to determine if interleukin-1 (IL-1) acts as a chemical messenger in the central nervous system (CNS) regulation of gastric secretion and ulcer formation, using male Wistar rats. The central injection of IL-1 dose-dependently inhibited gastric acid secretion in pylorus-ligated rats at 1...

journal_title：Biochemical and biophysical research communications

authors： Uehara A,Okumura T,Kitamori S,Takasugi Y,Namiki M

更新日期：1990-12-14 00:00:00

abstract：:The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, s...

journal_title：Biochemical and biophysical research communications

authors： Marcote MJ,González-Bosch C,Miralles VJ,Hernández-Yago J,Grisolía S

更新日期：1989-01-16 00:00:00