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Cell free translation of rat adrenal messenger RNA coding for an ACTH-induced protein.

Abstract：

:Protein markers induced by hormones are the necessary probes to study hormone regulation of gene expression. We have previously shown that ACTH was able to induce one of these markers in the cytosol of the rat adrenal: protein E (Dazord et al, Biochem. J., 176, 233-239, 1978). In this paper by using adrenal mRNA from control and in vivo ACTH treated rats as well as protein E antibodies, we show that: 1) ACTH affects both the amount of adrenal mRNA and its translational activity; 2) the translation of protein E is increased by the hormone; 3) protein E is the major translational product following ACTH treatment.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Langlois-Gallet D,Dazord A

doi

10.1016/0006-291x(84)90869-6

subject

Has Abstract

pub_date

1984-03-30 00:00:00

pages

975-81

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(84)90869-6

journal_volume

119

pub_type

杂志文章

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