Abstract:
:Chromosomal replication was studied by means of the BrdU-Höchst-Giemsa-technique in three minute T-cell leukemias with special regard to chromosome 15. In all the three leukemic cell lines the normally early replicating band 15 E was undetectable whereas late replication in this region is completely unaltered. Furthermore, R-banding, the structural homologue of early replication banding, remains unchanged. This observation is interpreted as a shift in the time point of replication during the S-phase of region 15 E, though the exact timing of replication of this region in tumor chromosomes remains unresolved.
journal_name
Chromosomajournal_title
Chromosomaauthors
Somssich IE,Spira J,Hameister H,Klein Gdoi
10.1007/BF00288676subject
Has Abstractpub_date
1982-01-01 00:00:00pages
197-208issue
2eissn
0009-5915issn
1432-0886journal_volume
86pub_type
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