Abstract:
:Recently, the kinetics of fast axonal transport of a single type of organelle, the serotonergic storage vesicle, was described in an identified axon of Aplysia using a pulsing technique combined with intracellular injection of [3H]serotonin. Here we extended the single axon studies by analyzing the movement of pulses of [3H]glycoprotein, following injection into the giant Aplysia cell, R2, of the amino sugar [3H]N-acetylgalactosamine. This glycoprotein precursor has been shown to label several organelles in this neuron. [3H]Glycoprotein is found to move in the axon of R2 at 2 rates of fast transport, 174 and 105 mm per day at room temperature. We suggest that the 2 rates reflect movements of 2 different types of organelle.
journal_name
Brain Resjournal_title
Brain researchauthors
Goldberg DJ,Ambron RTdoi
10.1016/0006-8993(81)91006-4subject
Has Abstractpub_date
1981-12-21 00:00:00pages
445-55issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(81)91006-4journal_volume
229pub_type
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