beta-Adrenergic induction of tyrosine aminotransferase organ culture of fetal rat and fetal human liver.

abstract：:Estrogen-based hormone therapy (HT) in postmenopausal women may reduce the risk of Alzheimer's disease (AD), although HT remains controversial. One key concern with HT is the potential of adverse outcomes such as breast and uterine cancer. A promising strategy to maximize HT benefits and minimize HT risks is the use o...

journal_title：Endocrinology

authors： Carroll JC,Pike CJ

更新日期：2008-05-01 00:00:00

abstract：:Estrogens have been shown to have positive and negative effects on anxiety and depressive-like behaviors, perhaps explained by the existence of two distinct estrogen receptor (ER) systems, ERalpha and ERbeta. The ERbeta agonist, diarylpropionitrile (DPN) has been shown to have anxiolytic properties in rats. DPN exists...

journal_title：Endocrinology

authors： Weiser MJ,Wu TJ,Handa RJ

更新日期：2009-04-01 00:00:00

abstract：:The relationship between progesterone and prostaglandin (PG) secretion in the pseudopregnant rabbit corpus luteum was investigated using isolated in vitro perfused ovaries. Progesterone and PG secretion were measured on days 1, 11, and 18 of hCG-induced pseudopregnancy. The mean progesterone secretion increased signif...

journal_title：Endocrinology

authors： Dharmarajan AM,Sueoka K,Miyazaki T,Atlas SJ,Ghodgaonkar RB,Dubin NH,Zirkin BR,Wallach EE

更新日期：1989-03-01 00:00:00

abstract：:We have examined expression of the chicken PRL receptor (cPRLR) gene in different tissues of the chicken by Northern blot analysis. Most tissues examined (ovary, testis, oviduct, kidney, and fat) possess a prominent full-length (4.6-kb) cPRLR transcript. A larger (11.7-kb) transcript is also detected in ovary, oviduct...

journal_title：Endocrinology

authors： Mao JN,Burnside J,Li L,Tang J,Davolos C,Cogburn LA

更新日期：1999-03-01 00:00:00

abstract：:The expression of the lutropin receptor (LHR) in granulosa cells is a complex phenomenon under the hormonal control of FSH and estradiol. Using primary cultures of granulosa cells from immature female rats pretreated with diethylstilbestrol (a compound with estrogen-like activity), the role of FSH in LHR induction was...

journal_title：Endocrinology

authors： Chen S,Shi H,Liu X,Segaloff DL

更新日期：1999-05-01 00:00:00

abstract：:In a previous paper, we demonstrated that an inhibitory action of excess iodide on thyrotropin-induced thyroid hormone secretion occurs at a site subsequent to the generation of cyclic AMP. In the present study, however, we have found that thyroidal cyclic AMP formation induced by thyrotropin in vitro was markedly inh...

journal_title：Endocrinology

authors： Hashizume K,Akasu F,Takazawa K,Endo W,Onaya T

更新日期：1976-12-01 00:00:00

abstract：:In this study, the potential interactions between dihydrotestosterone (DHT), a survival factor, and transforming growth factor-beta (TGF-beta), an apoptotic inducer, were examined in a derivative of the hormone-sensitive prostate cancer cell line LNCAP: The LNCaP TGF-beta receptor II cells, engineered to express TGF-b...

journal_title：Endocrinology

authors： Bruckheimer EM,Kyprianou N

更新日期：2001-06-01 00:00:00

abstract：:The effects of pineal indole compounds on the response of the neonatal rat anterior pituitary gland to LH-releasing hormone (LHRH) were studied in organ culture. After 24 h of culture under control conditions, pituitary glands from 5-day-old female rats were routinely incubated for an additional 24 h with the test com...

journal_title：Endocrinology

authors： Martin JE,Engel JN,Klein DC

更新日期：1977-03-01 00:00:00

abstract：:The previously reported synchronous oscillations in plasma glucose and insulin levels have been further studied to determine whether the phenomenon can be attributed to cyclic secretion or degradation of the hormone. Plasma C-peptide concentrations were measured and found to cycle with the same period as plasma insuli...

journal_title：Endocrinology

authors： Koerker DJ,Goodner CJ,Hansen BW,Brown AC,Rubenstein AH

更新日期：1978-05-01 00:00:00

abstract：:Sex differences in vocal communication are prevalent in both the animals and humans. The mechanism(s) mediating gender differences in human language are unknown, although, sex hormones, principally androgens, play a central role in the development of vocalizations in a wide variety of animal species. The discovery of ...

journal_title：Endocrinology

authors： Bowers JM,Perez-Pouchoulen M,Roby CR,Ryan TE,McCarthy MM

更新日期：2014-12-01 00:00:00

abstract：:The placenta is the primary source of estrogens and progesterone during pregnancy. Because pregnant diabetic women are reported to have lower serum estrogen and higher progesterone levels than nondiabetic pregnant women, and placental insulin-like growth factor II (IGF-II) production may be elevated during diabetic pr...

journal_title：Endocrinology

authors： Nestler JE

更新日期：1990-11-01 00:00:00

abstract：:Thyroid cell growth and function are regulated by hormones and growth factors binding to cell surface receptors that are coupled via G proteins, Gs and Gq, to the adenylyl cyclase and phospholipase C signal transduction systems, respectively. Activating mutations of the TSH receptor and G alpha s have been documented ...

journal_title：Endocrinology

authors： Zeiger MA,Saji M,Gusev Y,Westra WH,Takiyama Y,Dooley WC,Kohn LD,Levine MA

更新日期：1997-08-01 00:00:00

abstract：:The amount and sources of T3 associated with high affinity, low capacity cellular nuclear receptors in brown adipose tissue (BAT) have been estimated by in vivo pulse-labeling techniques. Maximal binding capacity was measured by in vivo saturation analysis. Nuclear receptor occupancy at endogenous levels of T3 and T4 ...

journal_title：Endocrinology

authors： Bianco AC,Silva JE

更新日期：1987-01-01 00:00:00

abstract：:We studied the effect of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) activation on serum concentrations and tissue expression of resistin, adiponectin, and adiponectin receptor-1 and -2 (AdipoR1 and AdipoR2) mRNA in normal mice and mice with insulin resistance induced by lipogenic, simple-carbohydrat...

journal_title：Endocrinology

authors： Haluzik MM,Lacinova Z,Dolinkova M,Haluzikova D,Housa D,Horinek A,Vernerova Z,Kumstyrova T,Haluzik M

更新日期：2006-09-01 00:00:00

abstract：:The rate-limiting event for combination of hCG alpha- and beta-subunits in JAR choriocarcinoma cells is the rate of disulfide bond formation in the beta-subunit. This is accompanied by a conformational change that produces a combination-competent form of the beta-subunit. The combination reaction, however, is incomple...

journal_title：Endocrinology

authors： Beebe JS,Huth JR,Ruddon RW

更新日期：1990-01-01 00:00:00

abstract：:Clinical studies indicate alternate-day, intermittent fasting (IMF) protocols result in meaningful weight loss in obese individuals. To further understand the mechanisms sustaining weight loss by IMF, we investigated the metabolic and neural alterations of IMF in obese mice. Male C57/BL6 mice were fed a high-fat diet ...

journal_title：Endocrinology

authors： Gotthardt JD,Verpeut JL,Yeomans BL,Yang JA,Yasrebi A,Roepke TA,Bello NT

更新日期：2016-02-01 00:00:00

abstract：:The monocarboxylate transporter Mct10 (Slc16a10; T-type amino acid transporter) facilitates the cellular transport of thyroid hormone (TH) and shows an overlapping expression with the well-established TH transporter Mct8. Because Mct8 deficiency is associated with distinct tissue-specific alterations in TH transport a...

journal_title：Endocrinology

authors： Müller J,Mayerl S,Visser TJ,Darras VM,Boelen A,Frappart L,Mariotta L,Verrey F,Heuer H

更新日期：2014-01-01 00:00:00

abstract：:The biosynthesis of various hypothalamic neuropeptides has been previously reported in anterior pituitary cells but not in intermediate lobe cells. We have recently demonstrated the occurrence of two somatostatin isoforms in the frog brain, namely somatostatin-14 (SS1) and [Pro(2),Met(13)]somatostatin-14 (SS2). In the...

journal_title：Endocrinology

authors： Tostivint H,Vieau D,Chartrel N,Boutelet I,Galas L,Fournier A,Lihrmann I,Vaudry H

更新日期：2002-09-01 00:00:00

abstract：:The concentration of biologically active LH in rhesus monkey (Macaca mulatta) serum was measured by a highly sensitive bioassay based upon testosterone production by dispersed rat interstitial cells. The sensitivity of the in vitro bioassay was equal to or higher than that of radioimmunoassay, with detection limits of...

journal_title：Endocrinology

authors： Dufau ML,Hodgen GD,Goodman AL,Catt KJ

更新日期：1977-06-01 00:00:00

abstract：:T4-binding globulin (TBG), the principal carrier of thyroid hormone in serum, is a glycoprotein containing 20% carbohydrate. The importance of the carbohydrate moiety has been previously studied by enzymatic deglycosylation, which showed that deglycosylated TBG retains its original immunological an T4-binding properti...

journal_title：Endocrinology

authors： Murata Y,Magner JA,Refetoff S

更新日期：1986-04-01 00:00:00

abstract：:Deciduomal reactions in response to artificial stimuli were induced on the tube-ligated uterine horns of unilateral pregnant hamsters. Serum progesterone levels were determined, and the changes of estrogen and progesterone receptors (ER and PR, respectively) were simultaneously studied in the deciduoma. After stimulat...

journal_title：Endocrinology

authors： Chen TJ,Hwang TC,Huang CC,Jow GM,Yu JY

更新日期：1989-07-01 00:00:00

abstract：:A biologically active form of the epidermal growth factor (EGF) precursor has been detected in human fluids and secretions. The secreted protein identified in human urine and milk has an apparent molecular mass of 160-170 kilodaltons and exhibits an affinity for the glycosaminoglycan heparin. More importantly, the sec...

journal_title：Endocrinology

authors： Mroczkowski B,Reich M

更新日期：1993-01-01 00:00:00

abstract：:The expression of the proopiomelanocortin (POMC) gene by normal lung and thyroid was examined by measurement of the content of ACTH, beta-lipotropin (beta LPH), and beta-endorphin (beta EP) in porcine lung and thyroid tissue. Acid extracts of normal porcine lung and thyroid tissue each contained appreciable amounts of...

journal_title：Endocrinology

authors： Clements JA,Funder JW,Tracy K,Morgan FJ,Campbell DJ,Lewis P,Hearn MT

更新日期：1982-12-01 00:00:00

abstract：:GH3 rat pituitary cells have L-type voltage-gated calcium channels, and both the rate of uptake of 45Ca2+ and the concentration of intracellular free calcium ion ([Ca2+]i) are increased by depolarization with high potassium. Cells incubated for several days with 10 nM epidermal growth factor (EGF) responded to depolar...

journal_title：Endocrinology

authors： Hinkle PM,Nelson EJ,Haymes AA

更新日期：1993-07-01 00:00:00

abstract：:Complementary DNA-encoding proteins with high homology to steroidogenic acute regulatory proteins (StAR) of mammals were cloned from rainbow trout head kidney and a mixture of several brook trout tissues. A cDNA encoding an MLN64 homolog was also cloned from brook trout. The C-terminal domains of rainbow trout StAR an...

journal_title：Endocrinology

authors： Kusakabe M,Todo T,McQuillan HJ,Goetz FW,Young G

更新日期：2002-06-01 00:00:00

abstract：:PTH stimulates synthesis and secretion of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] in renal proximal tubule cells through activation of the protein kinase-A (PKA) or the protein kinase-C (PKC) signaling pathway. The relative contribution of the two transducing systems was explored using PTH fragments with selective act...

journal_title：Endocrinology

authors： Janulis M,Wong MS,Favus MJ

更新日期：1993-08-01 00:00:00

abstract：:Estrogens are crucial for growth and function of the female genital tract. Recently, we showed that induction of uterine epithelial proliferation by estradiol is a paracrine event requiring an estrogen receptor-positive stroma. Growth factors [such as EGF (epidermal growth factor) ligands] are likely paracrine mediato...

journal_title：Endocrinology

authors： Hom YK,Young P,Wiesen JF,Miettinen PJ,Derynck R,Werb Z,Cunha GR

更新日期：1998-03-01 00:00:00

abstract：:The mechanisms underlying the glucose dependence of arginine vasopressin (AVP)-stimulated insulin secretion were examined in a hamster insulin-secreting cell line (HIT cells). At 1.67 mM glucose, 100 nM AVP stimulated biphasic changes in free cytosolic Ca2+ ([Ca2+]i) and insulin secretion. The initial spike of [Ca2+]i...

journal_title：Endocrinology

authors： Lu M,Soltoff SP,Yaney GC,Boyd AE 3rd

更新日期：1993-05-01 00:00:00

abstract：:C-type natriuretic peptide (CNP), found in endothelial cells, chondrocytes, and neurons, binds its cognate transmembrane receptor, natriuretic peptide receptor-B (NPR-B/GC-B), and stimulates the synthesis of the intracellular signaling molecule, cGMP. The known physiologic consequences of this binding event are vasore...

journal_title：Endocrinology

authors： Abbey SE,Potter LR

更新日期：2003-01-01 00:00:00

abstract：:Dopamine D2 receptor agonists are commonly used in the control of PRL-secreting adenomas, and the sensitivity of dopamine agonists during long term therapy is exquisite. However, the molecular mechanisms responsible for the maintenance of this cellular sensitivity to dopamine agonists remain poorly understood. In the ...

journal_title：Endocrinology

authors： Ng GY,Varghese G,Chung HT,Trogadis J,Seeman P,O'Dowd BF,George SR

更新日期：1997-10-01 00:00:00