Sign language aphasia due to left occipital lesion in a deaf signer.

abstract：:We performed brain MRIs on 21 patients with CNS sarcoidosis. Brain CTs were performed in 18 of these. Parenchymal lesions were seen in 17 of 21 with MRI, compared with 9 of 18 with CT. MRI detected a greater number of parenchymal lesions in cases where both CT and MRI were positive, and some lesions appeared more exte...

journal_title：Neurology

authors： Miller DH,Kendall BE,Barter S,Johnson G,MacManus DG,Logsdail SJ,Ormerod IE,McDonald WI

更新日期：1988-03-01 00:00:00

abstract：:Functional decline for each decade at symptom onset and need for cane, walker, or wheelchair were assessed in 78 biopsy-proved patients with sporadic inclusion body myositis. Patients with disease onset between 40 and 59 years used a walker after 10.2 +/- 5.8 years, whereas those with disease onset between 60 and 79 y...

journal_title：Neurology

authors： Peng A,Koffman BM,Malley JD,Dalakas MC

更新日期：2000-07-25 00:00:00

abstract：OBJECTIVE:To evaluate possible abnormal increase in thalamic glutamate/glutamine levels for restless legs syndrome (RLS) indicating increased glutamatergic activity producing arousal that at night disrupts and shortens sleep. METHODS:(1)H MRS of the right thalamus was performed using a 1.5 T GE MRI scanner and the PRO...

journal_title：Neurology

authors： Allen RP,Barker PB,Horská A,Earley CJ

更新日期：2013-05-28 00:00:00

abstract：:A number of high-quality studies have recently been published that examine the association between neuropathic pain and health-related quality of life (HRQoL). The current review identified 52 such studies in patients with six neuropathic pain conditions associated with lesions of either the peripheral (postsurgical n...

journal_title：Neurology

authors： Jensen MP,Chodroff MJ,Dworkin RH

更新日期：2007-04-10 00:00:00

abstract：BACKGROUND:Treatment of aneurysmal subarachnoid hemorrhage (SAH) has changed substantially over the last 25 years but there is a lack of reliable population-based data on whether case-fatality or functional outcomes have improved. METHODS:We determined changes in the standardized incidence and outcome of SAH in the sa...

journal_title：Neurology

authors： Lovelock CE,Rinkel GJ,Rothwell PM

更新日期：2010-05-11 00:00:00

abstract：:The authors searched for mutations in CACNA1A in patients with episodic ataxia and describe the clinical spectrum in genetically defined patients. Eighteen families and nine sporadic cases of episodic ataxia were evaluated for mutations in CACNA1A. The families were first genotyped to check for linkage to the chromoso...

journal_title：Neurology

authors： Jen J,Kim GW,Baloh RW

更新日期：2004-01-13 00:00:00

abstract：:A 64-year-old man with diffuse atherosclerosis developed an organic mental syndrome, followed by hypothalamic symptoms. Autopsy showed an old large cystic infarct involving the left temporal lobe including the hippocampus, and atrophy of the ipsilateral fornix, mammillary body, hypothalamus, mammillothalamic tract, an...

journal_title：Neurology

authors： Torch WC,Hirano A,Solomon S

更新日期：1977-12-01 00:00:00

abstract：:Parenchymatous intracerebral hemorrhage (ICH) is a serious, infrequent complication of thrombolytic therapy for acute myocardial infarction. We studied the clinical and radiologic features, manner of presentation, associated factors, and temporal course in 23 patients with ICH associated with 150 mg or 100 mg recombin...

journal_title：Neurology

authors： Sloan MA,Price TR,Petito CK,Randall AM,Solomon RE,Terrin ML,Gore J,Collen D,Kleiman N,Feit F

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To investigate whether the presence of cerebral microbleeds, which present as focal lesions on imaging, is associated with a diffuse loss of white matter microstructural integrity in the brain. METHODS:In the prospective, population-based Rotterdam Scan Study, a total of 4,493 participants underwent brain MR...

journal_title：Neurology

authors： Akoudad S,de Groot M,Koudstaal PJ,van der Lugt A,Niessen WJ,Hofman A,Ikram MA,Vernooij MW

更新日期：2013-11-26 00:00:00

abstract：:Both mevalonic aciduria, characterized by psychomotor retardation, cerebellar ataxia, recurrent fever attacks, and death in early childhood, and hyper-immunoglobulin D (hyper-IgD) syndrome, with recurrent fever attacks without neurologic symptoms, are caused by a functional deficiency of mevalonate kinase. In a system...

journal_title：Neurology

authors： Simon A,Kremer HP,Wevers RA,Scheffer H,De Jong JG,Van Der Meer JW,Drenth JP

更新日期：2004-03-23 00:00:00

abstract：BACKGROUND:Ependymoma is a rare type of glioma, representing 5% of all CNS malignancies. Radiotherapy (RT) is commonly administered, but there is no standard chemotherapy. At recurrence, ependymoma is notoriously refractory to therapy and the prognosis is poor. In recurrent glioblastoma, encouraging responses with beva...

journal_title：Neurology

authors： Green RM,Cloughesy TF,Stupp R,DeAngelis LM,Woyshner EA,Ney DE,Lassman AB

更新日期：2009-11-17 00:00:00

abstract：:The "modified host protein" model of scrapie proposes that the transmissible agent is composed of the degradation-resistant protein, Sp33-37, and that clinical and pathologic signs result from neurotoxic accumulations of this protein. Sp33-37 is an abnormal, amyloidogenic isoform of the normally occurring cellular pro...

journal_title：Neurology

authors： Bendheim PE,Brown HR,Rudelli RD,Scala LJ,Goller NL,Wen GY,Kascsak RJ,Cashman NR,Bolton DC

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To investigate the lateralization and localization of ictal EEG in focal epilepsy. METHODS:A total of 486 ictal EEG of 72 patients with focal epilepsy arising from the mesial temporal, neocortical temporal, mesial frontal, dorsolateral frontal, parietal, and occipital regions were analyzed. RESULTS:Surface ...

journal_title：Neurology

authors： Foldvary N,Klem G,Hammel J,Bingaman W,Najm I,Lüders H

更新日期：2001-12-11 00:00:00

abstract：:We analyzed frozen brain specimens from three patients with subacute sclerosing panencephalitis (SSPE) for the presence of interleukin (IL)-1 beta, IL-2, IL-6, tumor necrosis factor (TNF), lymphotoxin (LT), and interferon (IFN)-gamma using immunocytochemical techniques. We detected these cytokines in SSPE brain lesion...

journal_title：Neurology

authors： Nagano I,Nakamura S,Yoshioka M,Onodera J,Kogure K,Itoyama Y

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To evaluate attention deficit in Alzheimer's disease (AD) and its relationship to attention deficits associated with aging and with medications altering alertness. METHODS:Ten patients with probable AD, 10 healthy old controls, and 15 young controls performed a covert orienting of spatial attention task. You...

journal_title：Neurology

authors： Oken BS,Kishiyama SS,Kaye JA,Howieson DB

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To update the 1997 American Academy of Neurology (AAN) practice parameter regarding sports concussion, focusing on 4 questions: 1) What factors increase/decrease concussion risk? 2) What diagnostic tools identify those with concussion and those at increased risk for severe/prolonged early impairments, neurolo...

journal_title：Neurology

authors： Giza CC,Kutcher JS,Ashwal S,Barth J,Getchius TS,Gioia GA,Gronseth GS,Guskiewicz K,Mandel S,Manley G,McKeag DB,Thurman DJ,Zafonte R

更新日期：2013-06-11 00:00:00

abstract：:Seronegative (SN) patients with myasthenia gravis (MG) have clinical and electrophysiologic features similar to those of seropositive (SP) patients, and they respond to the same therapeutic measures. However, because SN patients lack detectable (by standard radioimmunoassays) serum antibodies to acetylcholine receptor...

journal_title：Neurology

authors： Karni A,Zisman E,Katz-Levy Y,Paas-Rozner M,Dayan M,Brautbar C,Abramsky O,Sela M,Mozes E

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:To determine whether the CT angiography (CTA) spot sign marks bleeding complications during and after surgery for spontaneous intracerebral hemorrhage (ICH). METHODS:In a 2-center study of consecutive spontaneous ICH patients who underwent CTA followed by surgical hematoma evacuation, 2 experienced readers (...

journal_title：Neurology

authors： Brouwers HB,Raffeld MR,van Nieuwenhuizen KM,Falcone GJ,Ayres AM,McNamara KA,Schwab K,Romero JM,Velthuis BK,Viswanathan A,Greenberg SM,Ogilvy CS,van der Zwan A,Rinkel GJ,Goldstein JN,Klijn CJ,Rosand J

更新日期：2014-09-02 00:00:00

abstract：:We reviewed the clinical and laboratory features of 81 patients who had trigeminal sensory neuropathy (TSN) and a connective tissue disease (CTD). The neuropathy developed before the symptoms of CTD in 6/81 patients (7%), and in 38/81 patients (47%) TSN and CTD were diagnosed concurrently. The most frequently associat...

journal_title：Neurology

authors： Hagen NA,Stevens JC,Michet CJ Jr

更新日期：1990-06-01 00:00:00

abstract：:The motor effects of direct agonists which act selectively on certain dopamine receptors were studied in monkeys rendered hemiparkinsonian by unilateral intracarotid injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The D-2 dopamine agonist, LY 171555, but not the D-1 agonist, SKF 38393, reduced parkin...

journal_title：Neurology

authors： Barone P,Bankiewicz KS,Corsini GU,Kopin IJ,Chase TN

更新日期：1987-10-01 00:00:00

abstract：:Children with epilepsy have more behavioral and cognitive problems than children with other chronic illnesses and children in the general population. Risk factors are multiple, probably involving a combination of neurological, seizure, family, and child variables. Problems with attention and symptoms of depression occ...

journal_title：Neurology

authors： Dunn DW,Austin JK

更新日期：1999-01-01 00:00:00

abstract：:Impairment of object-bound movements of the hand performed under visual guidance ("optic ataxia") was a prominent sign in a patient with bilateral circumscribed infarctions in the posterior watershed territory. The sign was interpreted as resulting from defective integration of panoramic visual information with propri...

journal_title：Neurology

authors： Damasio AR,Benton AL

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Fragile X-associated tremor/ataxia syndrome (FXTAS) is a recently described, underrecognized neurodegenerative disorder of aging fragile X mental retardation 1 (FMR1) premutation carriers, particularly men. Core motor features are action tremor, gait ataxia, and parkinsonism. Carriers have expanded CGG repea...

journal_title：Neurology

authors： Leehey MA,Berry-Kravis E,Goetz CG,Zhang L,Hall DA,Li L,Rice CD,Lara R,Cogswell J,Reynolds A,Gane L,Jacquemont S,Tassone F,Grigsby J,Hagerman RJ,Hagerman PJ

更新日期：2008-04-15 00:00:00

abstract：:This review summarizes evidence, primarily from recent human studies, indirectly supporting a novel hypothesis: that the assessment of healthy individuals' responses to standardized noxious stimuli in a controlled laboratory environment has important implications for the later risk of developing a broad spectrum of ch...

journal_title：Neurology

authors： Edwards RR

更新日期：2005-08-09 00:00:00

abstract：OBJECTIVE:To characterize children with new-onset seizures presenting as status epilepticus at a tertiary care children's hospital. METHODS:Prospectively collected data were reviewed from a database derived from a mandated critical care pathway. A total of 1,382 patients presented with new-onset seizures between 2001 ...

journal_title：Neurology

authors： Singh RK,Stephens S,Berl MM,Chang T,Brown K,Vezina LG,Gaillard WD

更新日期：2010-02-23 00:00:00

abstract：:We studied 10 patients with transient global amnesia (TGA). Routine electroencephalograms (EEGs) were normal in six; two showed mild temporal lobe abnormalities, one had bitemporal delta activity with rare sharp waves, and one showed bioccipital rhythmic theta activity. Nasopharyngeal (NP) recordings were obtained in ...

journal_title：Neurology

authors： Rowan AJ,Protass LM

更新日期：1979-06-01 00:00:00

abstract：:In the Clinical/Scientific Note “CNS neutrophilic vasculitis in neuro-Sweet disease” by R. Charlson et al. (Neurology® 2015;85:829–830), there is an error in the discussion and the references. The last name of the first author of reference 2 should be Hisanaga, not Hisanga as originally published. The authors regret t...

journal_title：Neurology

authors：

更新日期：2015-11-17 00:00:00

abstract：OBJECTIVES:To test the hypothesis that neuropsychiatric symptomatology is predictive of the success of seizure control in patients newly treated with antiepileptic drugs (AEDs), and that this predictive value adds to that provided by other clinical, imaging, and genomic factors in a multivariate model. METHODS:One hun...

journal_title：Neurology

authors： Petrovski S,Szoeke CE,Jones NC,Salzberg MR,Sheffield LJ,Huggins RM,O'Brien TJ

更新日期：2010-09-14 00:00:00

abstract：:We previously reported a large Charcot-Marie-Tooth family not linked to the Duffy blood group marker, supporting the existence of genetic heterogeneity in this neuropathy. In order to investigate the possibility of another disease locus on chromosome 1, we analyzed this family further, using DNA polymorphisms of 6 gen...

journal_title：Neurology

authors： Raeymaekers P,De Jonghe P,Backhovens H,Wehnert A,De Winter G,Swerts L,Gheuens J,Martin JJ,Vandenberghe A,Van Broeckhoven C

更新日期：1989-06-01 00:00:00

abstract：:We performed an open-label study testing the effects of GM1 ganglioside on 10 Parkinson's disease (PD) patients. Patients received 1,000 mg of GM1 by IV infusion after the last of three baseline functional assessments. Patients then self-administered GM1 at a dose of 200 mg/d, by subcutaneous injection, for 18 weeks. ...

journal_title：Neurology

authors： Schneider JS,Roeltgen DP,Rothblat DS,Chapas-Crilly J,Seraydarian L,Rao J

更新日期：1995-06-01 00:00:00