Arm-diaphragm synkinesis: electrodiagnostic studies of aberrant regeneration of phrenic motor neurons.

abstract：:We developed a method for the detection of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) carriers. The method is based on the quantitative analysis of the products of standard multiplex polymerase chain reaction (PCR) from 18 different exons of the dystrophin gene, and is designated "QM-PCR." W...

journal_title：Neurology

authors： Ioannou P,Christopoulos G,Panayides K,Kleanthous M,Middleton L

更新日期：1992-09-01 00:00:00

abstract：:We tested the effect of bovine cortex phosphatidylserine (BC-PS), a membrane phospholipid known to inhibit the release of the cytokine tumor necrosis factor (TNF), in SJL/J mice sensitized for adoptively transferred experimental autoimmune encephalomyelitis (EAE). Control, sensitized mice developed severe clinical and...

journal_title：Neurology

authors： Monastra G,Cross AH,Bruni A,Raine CS

更新日期：1993-01-01 00:00:00

abstract：:To learn if limb-kinetic apraxia (LKA) is associated with Parkinson disease (PD), participants with PD (on medications) and control subjects performed finger tapping (FT), measuring movement speed, and performed coin rotation (CR), measuring precise coordinated but independent finger movements and speed. There were no...

journal_title：Neurology

authors： Quencer K,Okun MS,Crucian G,Fernandez HH,Skidmore F,Heilman KM

更新日期：2007-01-09 00:00:00

abstract：:We evaluated four formulas for estimating the intra-blood-brain barrier (IBBB) synthesis of IgG in a computer model of two types of BBB damage and in 1,629 consecutively received pairs of CSF and serum. These four formulas were the IgG synthesis rate (SR), IgG(loc) (ie, local), IgG index, and IgG extended index. Resul...

journal_title：Neurology

authors： Peter JB,Bowman RL

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:To explore the inflammatory processes in the pathogenesis of psychiatric symptoms and the prognostic value of psychiatric comorbidities in multiple sclerosis (MS). METHODS:Four hundred five patients with relapsing-remitting (RR) MS underwent psychiatric evaluation by means of Beck Depression Inventory II (BD...

journal_title：Neurology

authors： Rossi S,Studer V,Motta C,Polidoro S,Perugini J,Macchiarulo G,Giovannetti AM,Pareja-Gutierrez L,Calò A,Colonna I,Furlan R,Martino G,Centonze D

更新日期：2017-09-26 00:00:00

abstract：OBJECTIVE:To examine the association of change in body mass index (BMI) with risk of Alzheimer disease (AD). METHODS:Nine hundred eighteen older Catholic clergy participating in the Religious Orders Study without dementia at baseline were studied. Outcome measures were the clinical diagnosis of AD and change in cognit...

journal_title：Neurology

authors： Buchman AS,Wilson RS,Bienias JL,Shah RC,Evans DA,Bennett DA

更新日期：2005-09-27 00:00:00

abstract：OBJECTIVE:Among the rare causes of myelopathies is primary intramedullary spinal cord lymphoma (PISCL). As PISCL is often underrecognized, delaying appropriate treatment, we sought to describe its presentation, imaging characteristics, and outcomes. METHODS:Mayo Clinic medical records, lymphoma database, and autopsies...

journal_title：Neurology

authors： Flanagan EP,O'Neill BP,Porter AB,Lanzino G,Haberman TM,Keegan BM

更新日期：2011-08-23 00:00:00

abstract：OBJECTIVE:To describe the clinical characteristics and clinical-anatomic correlations of homonymous hemianopia (HH). BACKGROUND:Homonymous hemianopia impairs visual function and frequently precludes driving. Most knowledge of HH is based on relatively few cases with clinical-anatomic correlations. METHODS:The authors...

journal_title：Neurology

authors： Zhang X,Kedar S,Lynn MJ,Newman NJ,Biousse V

更新日期：2006-03-28 00:00:00

abstract：:Using a 1.5-tesla GE Signa MR scanner, we imaged the brains of 14 right-handed Tourette's syndrome (TS) patients (11 men, three women), aged 18 to 49 years, who had minimal lifetime neuroleptic exposure. We also studied an equal number of normal controls individually matched for age, sex, and handedness and group-matc...

journal_title：Neurology

authors： Peterson B,Riddle MA,Cohen DJ,Katz LD,Smith JC,Hardin MT,Leckman JF

更新日期：1993-05-01 00:00:00

abstract：:The authors studied the association of an exon 4 (E4*epsilon2/3/4) and three promoter polymorphisms of APOE with disease course and severity stratified by gender in 221 patients with multiple sclerosis from two overlapping population-based prevalence cohorts. Women carriers of the E4*epsilon2 allele took longer to att...

journal_title：Neurology

authors： Kantarci OH,Hebrink DD,Achenbach SJ,Pittock SJ,Altintas A,Schaefer-Klein JL,Atkinson EJ,De Andrade M,McMurray CT,Rodriguez M,Weinshenker BG

更新日期：2004-03-09 00:00:00

abstract：:We describe a patient who presented with unilateral abdominal herniation due to weakness of abdominal musculature, associated with extensive syringomyelia. Electromyographic evidence of focal denervation and reinnervation was present in the weak muscles consistent with anterior horn cell loss. We compare these unusual...

journal_title：Neurology

authors： Coleman RJ,Ingram DA

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To investigate the presenting characteristics of new-onset afebrile seizures in infants (age 1-24 months) and the yield of neuroimaging. METHODS:Prospective data were obtained from a standardized evaluation and management plan mandated by a critical care pathway. A total of 317 infants presented with new-ons...

journal_title：Neurology

authors： Hsieh DT,Chang T,Tsuchida TN,Vezina LG,Vanderver A,Siedel J,Brown K,Berl MM,Stephens S,Zeitchick A,Gaillard WD

更新日期：2010-01-12 00:00:00

abstract：OBJECTIVE:To assess resting cerebral blood flow (CBF) in the whole-brain and cerebral white matter (WM) and gray matter (GM) of adults with Fabry disease (FD), using arterial spin labeling (ASL) MRI, and to investigate CBF correlations with WM hyperintensity (WMH) volume and the circulating biomarker lyso-Gb3. METHODS...

journal_title：Neurology

authors： Phyu P,Merwick A,Davagnanam I,Bolsover F,Jichi F,Wheeler-Kingshott C,Golay X,Hughes D,Cipolotti L,Murphy E,Lachmann RH,Werring DJ

更新日期：2018-04-17 00:00:00

abstract：:This update to the American Academy of Neurology's 1998 position statement endeavors to provide guidance for the consistent ethical conduct and review of neurologic research involving human participants. It does so by outlining a widely used ethical framework of 7 principles derived from the foundational documents of ...

journal_title：Neurology

authors： Tolchin B,Conwit R,Epstein LG,Russell JA,Ethics, Law, and Humanities Committee, a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society.

更新日期：2020-04-14 00:00:00

abstract：OBJECTIVE:To identify modifying factors that preserve functional independence among individuals at high dementia risk. METHODS:Health and Retirement Study participants aged 65 years or older without baseline activities of daily living (ADL) limitations (n = 4,922) were interviewed biennially for up to 12 years. Dement...

journal_title：Neurology

authors： Rist PM,Capistrant BD,Wu Q,Marden JR,Glymour MM

更新日期：2014-04-29 00:00:00

abstract：:The clinical and electroencephalographic (EEG) effects of sodium valproate were studied in four patients by means of serial 24-hour EEG recordings and simultaneous hourly determinations of serum drug concentrations. The patients all had frequent clinical seizures and generalized spike-wave discharges. Valproate appear...

journal_title：Neurology

authors： Rowan AJ,Binnie CD,de Beer-Pawlikowski NK,Goedhart DM,Gutter T,van der Geest P,Meinardi H,Meijer JW

更新日期：1979-11-01 00:00:00

abstract：OBJECTIVE:To report the incidence of prion disease in the United States. METHODS:Prion disease decedents were retrospectively identified from the US national multiple cause-of-death data for 2003-2015 and matched with decedents in the National Prion Disease Pathology Surveillance Center (NPDPSC) database through compa...

journal_title：Neurology

authors： Maddox RA,Person MK,Blevins JE,Abrams JY,Appleby BS,Schonberger LB,Belay ED

更新日期：2020-01-14 00:00:00

abstract：:Dysfunction of NADH: ubiquinone oxidoreductase (complex I) of the mitochondrial electron transport chain has been linked to the pathogenesis of Parkinson's disease. While simple assays of complex I activity are unlikely to be useful in the preclinical detection of Parkinson's disease, other more sophisticated physical...

journal_title：Neurology

authors： Parker WD Jr

更新日期：1991-05-01 00:00:00

abstract：:We report the clinical and pathologic features of a patient with peripheral neuropathy that was the first clinical expression of cholesterol emboli syndrome (CES). Biopsy of skeletal muscle and peripheral nerve revealed cholesterol clefts in lumens of small arteries, necrotizing arteritis, and severe degeneration of p...

journal_title：Neurology

authors： Bendixen BH,Younger DS,Hair LS,Gutierrez C,Meyers ML,Homma S,Jaffe IA

更新日期：1992-02-01 00:00:00

abstract：:Over the past 5 years, and especially within the last year, there has been a rapid expansion of vagus nerve stimulation (VNS)-related preclinical research, as well as clinical studies in indications other than epilepsy. The research advances in understanding VNS are occurring in the midst of a blossoming of other form...

journal_title：Neurology

authors： George MS,Nahas Z,Bohning DE,Kozel FA,Anderson B,Chae JH,Lomarev M,Denslow S,Li X,Mu C

更新日期：2002-09-24 00:00:00

abstract：:We prospectively evaluated 84 consecutive adult patients with chronic liver disease before and after liver transplantation to define the type and frequency of post-transplant neurologic complications, and to assess possible pretransplant and operative variables associated with in-hospital CNS complications. There were...

journal_title：Neurology

authors： Pujol A,Graus F,Rimola A,Beltrán J,Garcia-Valdecasas JC,Navasa M,Grande L,Galofré J,Visa J,Rodés J

更新日期：1994-07-01 00:00:00

abstract：:There are multiple difficulties in evaluating new treatments for multiple sclerosis (MS). The clinical diagnosis is imprecise, and the correlation between lesion and clinical dysfunction is incomplete. The neurologic evaluation is complex and lacks full precision. The course of MS is complex and has limited predictabi...

journal_title：Neurology

authors： Brown JR

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Collagen abnormalities of skin have been reported among patients with ALS. However, little is known concerning glycosaminoglycans of the skin in ALS. Our objective was to clarify morphologic and biochemical findings of skin glycosaminoglycans among patients with ALS. METHODS:We performed morph...

journal_title：Neurology

authors： Ono S,Imai T,Aso A,Yamano T,Shimizu N,Nagao K

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Biomarker levels in blood after traumatic brain injury (TBI) may offer diagnostic and prognostic tools in addition to clinical indices. This study aims to validate glial fibrillary acidic protein (GFAP) and S100B concentrations in blood as outcome predictors of TBI using cutoff levels of 1.5 μg/L for GFAP an...

journal_title：Neurology

authors： Vos PE,Jacobs B,Andriessen TM,Lamers KJ,Borm GF,Beems T,Edwards M,Rosmalen CF,Vissers JL

更新日期：2010-11-16 00:00:00

abstract：OBJECTIVE:To compare nondemented patients with Parkinson's disease (PD) with and without REM sleep behavior disorder (RBD) to healthy controls on quantitative EEG characteristics for both wakefulness and REM sleep. METHODS:Fifteen patients with PD (7 patients with polysomnographic-confirmed RBD [PD-RBD] and 8 patients...

journal_title：Neurology

authors： Gagnon JF,Fantini ML,Bédard MA,Petit D,Carrier J,Rompré S,Décary A,Panisset M,Montplaisir J

更新日期：2004-02-10 00:00:00

abstract：OBJECTIVE:To determine the efficacy of acetyl-l-carnitine (ALCAR) on the rate of decline in early-onset AD patients. METHODS:A 1-year, multicenter, double-blind, placebo-controlled, randomized trial was conducted. Subjects were 45 to 65 years old, with a diagnosis of probable AD according to National Institute of Neur...

journal_title：Neurology

authors： Thal LJ,Calvani M,Amato A,Carta A

更新日期：2000-09-26 00:00:00

abstract：OBJECTIVE:To determine the diagnostic value of high-resolution ultrasound (HRUS) for detection of chronic inflammatory demyelinating polyneuropathy (CIDP), Lewis-Sumner syndrome (LSS), and multifocal motor neuropathy (MMN). METHODS:Between January 2013 and January 2015, we enrolled 75 consecutive treatment-naive patie...

journal_title：Neurology

authors： Goedee HS,van der Pol WL,van Asseldonk JH,Franssen H,Notermans NC,Vrancken AJ,van Es MA,Nikolakopoulos S,Visser LH,van den Berg LH

更新日期：2017-01-10 00:00:00

abstract：:We studied the effect of acetazolamide on plasma potassium in normals and in two patients with hyperkalemic periodic paralysis. Administration of acetazolamide for 48 hours lowered mean plasma potassium in normals from 4.01 to 3.56 mEq per liter (p less than 0.001) and in the patients from 4.55 to 4.00 mEq per liter (...

journal_title：Neurology

authors： Riggs JE,Griggs RC,Moxley RT 3rd,Lewis ED

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVE:We aimed to compare survival in the multiple sclerosis (MS) population with a matched cohort from the general population, and to evaluate the association of comorbidity with survival in both populations. METHODS:Using population-based administrative data, we identified 5,797 persons with MS and 28,807 contro...

journal_title：Neurology

authors： Marrie RA,Elliott L,Marriott J,Cossoy M,Blanchard J,Leung S,Yu N

更新日期：2015-07-21 00:00:00

abstract：OBJECTIVE:Alzheimer disease (AD) risk factors are present throughout the lifespan. This randomized controlled trial evaluated the effectiveness of various online education strategies concerning AD risk reduction and brain health in younger populations. METHOD:High school and college students were recruited via social ...

journal_title：Neurology

authors： Saif N,Niotis K,Dominguez M,Hodes JF,Woodbury M,Amini Y,Sadek G,Scheyer O,Caesar E,Hristov H,Knowlton N,Lee P,McInnis M,Isaacson RS

更新日期：2020-10-20 00:00:00