Acute effects of acetazolamide in hyperkalemic periodic paralysis.

Abstract:

:We studied the effect of acetazolamide on plasma potassium in normals and in two patients with hyperkalemic periodic paralysis. Administration of acetazolamide for 48 hours lowered mean plasma potassium in normals from 4.01 to 3.56 mEq per liter (p less than 0.001) and in the patients from 4.55 to 4.00 mEq per liter (p less than 0.001). This kaliopenic effect of acetazolamide may account for its therapeutic action in hyperkalemic periodic paralysis.

journal_name

Neurology

journal_title

Neurology

authors

Riggs JE,Griggs RC,Moxley RT 3rd,Lewis ED

doi

10.1212/wnl.31.6.725

subject

Has Abstract

pub_date

1981-06-01 00:00:00

pages

725-9

issue

6

eissn

0028-3878

issn

1526-632X

journal_volume

31

pub_type

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